DK473184A - Azetidioner - Google Patents

Azetidioner Download PDF

Info

Publication number: DK473184A
Authority: DK; Denmark
Prior art keywords: azetidions
Prior art date: 1983-10-03

Application number

DK473184A

Other languages

English (en)

Other versions

DK473184D0 (da

Inventor

Robert Zahler

William H Koster

William A Slusarchyk

Original Assignee

Squibb & Sons Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-10-03

Filing date

1984-10-02

Publication date

1985-04-04

1984-10-02 Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc

1984-10-02 Publication of DK473184D0 publication Critical patent/DK473184D0/da

1985-04-04 Publication of DK473184A publication Critical patent/DK473184A/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C07D205/085—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK473184A 1983-10-03 1984-10-02 Azetidioner DK473184A (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US53871983A	1983-10-03	1983-10-03
US06/599,841 US4576749A (en)	1983-10-03	1984-04-13	3-Acylamino-1-carboxymethylaminocarbonyl-2-azetidinones

Publications (2)

Publication Number	Publication Date
DK473184D0 DK473184D0 (da)	1984-10-02
DK473184A true DK473184A (da)	1985-04-04

Family

ID=27065905

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK473184A DK473184A (da)	1983-10-03	1984-10-02	Azetidioner

Country Status (5)

Country	Link
US (1)	US4576749A (da)
EP (1)	EP0138407A1 (da)
AU (1)	AU575848B2 (da)
CA (1)	CA1253146A (da)
DK (1)	DK473184A (da)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5229381A (en) *	1983-12-01	1993-07-20	Merck & Co., Inc.	Substituted azetidinones as anti-inflammatory and antidegenerative agents
US5229510A (en) *	1983-12-01	1993-07-20	Merck & Co., Inc.	β-lactams useful in determining the amount of elastase in a clinical sample
US5100880A (en) *	1991-03-20	1992-03-31	Merck & Co., Inc.	Novel betalactam elastase inhibitors containing phosphorous acid derivatives at the 4-position of the 2-azetidinone
US5104862A (en) *	1991-03-20	1992-04-14	Merck & Co., Inc.	Bethalactam elastase inhibitors containing phosphorous acid derivatives at the 4-position of the 2-azetidinone
US5348953A (en) *	1991-06-25	1994-09-20	Merck & Co., Inc.	Substituted azetidinones as anti-inflammatory and antidegenerative agents
JPH08502752A (ja) *	1992-10-27	1996-03-26	メルクエンドカンパニーインコーポレーテッド	抗炎症剤及び抗変性剤としての新規の置換アゼチジノン
US5591737A (en) *	1992-12-17	1997-01-07	Merck & Co., Inc.	Substituted azetidinones as anti-inflammatory and antidegenerative agents
US5631365A (en)	1993-09-21	1997-05-20	Schering Corporation	Hydroxy-substituted azetidinone compounds useful as hypocholesterolemic agents
US5747485A (en) *	1995-04-13	1998-05-05	Merck & Co., Inc.	Substituted azetidiones as anti-inflammatory and antidegenerative agents
US5883247A (en) *	1996-06-10	1999-03-16	Hoffmann-La Roche Inc.	Preparation of cephem and isooxacephem derivatives
US5741926A (en) *	1997-02-12	1998-04-21	Shaman Pharmaceuticals, Inc.	Aniline derivatives having antihyperglycemic activity
WO2000063703A1 (en)	1999-04-16	2000-10-26	Schering Corporation	Use of azetidinone compounds
US6982251B2 (en) *	2000-12-20	2006-01-03	Schering Corporation	Substituted 2-azetidinones useful as hypocholesterolemic agents
ATE369851T1 (de) *	2001-01-26	2007-09-15	Schering Corp	Kombinationen von gallensäuresequestriermitteln und hemmern der sterolabsorption zur behandlung von kardiovaskulären indikationen
TW200840563A (en) *	2001-01-26	2008-10-16	Schering Corp	Combinations of nicotinic acid and derivatives thereof and sterol absorption inhibitor(S) and treatments for vascular indications
IL156445A0 (en) *	2001-01-26	2004-01-04	Schering Corp	Combinations of peroxisome proliferator-activated receptor (ppar) activator(s) and sterol absorption inhibitor(s) and treatments for vascular indications
BR0206644A (pt) *	2001-01-26	2004-02-25	Schering Corp	Combinações de inibidor(es) de absorção de esteróis com agente(s) cardiovascular(es) para o tratamento de condições vasculares
SI1355644T1 (sl) *	2001-01-26	2006-10-31	Schering Corp	Uporaba substituiranih azetidinonskih spojin za zdravljenje sitosterolemije
US20060287254A1 (en) *	2001-01-26	2006-12-21	Schering Corporation	Use of substituted azetidinone compounds for the treatment of sitosterolemia
US7071181B2 (en) *	2001-01-26	2006-07-04	Schering Corporation	Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors
KR20040025890A (ko) *	2001-01-26	2004-03-26	쉐링 코포레이션	혈관성 질환을 치료하기 위한 스테롤 흡수 억제제와 혈액조절제의 조합물
US20030013699A1 (en) *	2001-05-25	2003-01-16	Davis Harry R.	Methods for treating alzheimer's disease and/or regulating levels of amyloid beta peptides in a subject
DK1427409T3 (da) *	2001-09-21	2009-01-12	Schering Corp	Fremgangsmåde til behandling eller forhindring af vaskulær inflammation under brug af en eller flere sterolabssorptionsinhibitorer
US7053080B2 (en) *	2001-09-21	2006-05-30	Schering Corporation	Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors
DK1429756T3 (da) *	2001-09-21	2007-03-19	Schering Corp	Behandling af xanthoma med azetidinonderivater som sterolabsorptionsinhibitorer
US20030119808A1 (en) *	2001-09-21	2003-06-26	Schering Corporation	Methods of treating or preventing cardiovascular conditions while preventing or minimizing muscular degeneration side effects
US7056906B2 (en) *	2001-09-21	2006-06-06	Schering Corporation	Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women
US6610845B1 (en)	2002-01-04	2003-08-26	Orchid Chemicals & Pharmaceuticals Limited, India	Thioester derivatives of thiazolyl acetic acid and their use in the preparation of cephalosporin compounds
US20040092499A1 (en) *	2002-11-06	2004-05-13	Schering Corporation	Methods and therapeutic combinations for the treatment of autoimmune disorders
WO2004081002A1 (en)	2003-03-07	2004-09-23	Schering Corporation	Substituted azetidinone compounds, formulations and uses thereof for the treatment of hypercholesterolemia
US7067509B2 (en) *	2003-03-07	2006-06-27	Neurocrine Biosciences, Inc.	Melanin-concentrating hormone receptor antagonists and compositions and methods related thereto
CN1756755A (zh) *	2003-03-07	2006-04-05	先灵公司	取代的2－吖丁啶酮化合物、其制剂及其治疗高胆甾醇血症的用途
ATE418551T1 (de) *	2003-03-07	2009-01-15	Schering Corp	Substituierte azetidinon-derivate, deren pharmazeutische formulierungen und deren verwendung zur behandlung von hypercholesterolemia
US7459442B2 (en) *	2003-03-07	2008-12-02	Schering Corporation	Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
WO2005046797A2 (en) *	2003-11-05	2005-05-26	Schering Corporation	Combinations of lipid modulating agents and substituted azetidinones and treatments for vascular conditions

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ199981A (en) *	1981-04-09	1985-08-16	Squibb & Sons Inc	2-oxo-1-(((substituted sulphonyl)amino)carbonyl)azetidines
CA1272726C (en) *	1982-01-04	1990-08-14		2-oxo-1-(aminocarbonylaminosulfonyl- aminocarbonyl)azetidines
US4939253A (en) *	1982-08-04	1990-07-03	E. R. Squibb & Sons, Inc.	2-oxoazetidin-1-yloxy acetic acids and analogs
CA1204746A (en) *	1982-08-19	1986-05-20	Hoffmann-La Roche Limited	.beta. LACTAMS

1984
- 1984-04-13 US US06/599,841 patent/US4576749A/en not_active Expired - Lifetime
- 1984-09-06 AU AU32781/84A patent/AU575848B2/en not_active Ceased
- 1984-09-14 CA CA000463205A patent/CA1253146A/en not_active Expired
- 1984-09-19 EP EP84306391A patent/EP0138407A1/en not_active Withdrawn
- 1984-10-02 DK DK473184A patent/DK473184A/da not_active Application Discontinuation

Also Published As

Publication number	Publication date
DK473184D0 (da)	1984-10-02
AU575848B2 (en)	1988-08-11
AU3278184A (en)	1985-04-18
EP0138407A1 (en)	1985-04-24
US4576749A (en)	1986-03-18
CA1253146A (en)	1989-04-25

Publication	Publication Date	Title
FI830256A0 (fi)	1983-01-26	Silplaot
DK473184D0 (da)	1984-10-02	Azetidioner
BR8400004A (pt)	1984-07-31	Retroprojetor
BR8400003A (pt)	1984-07-31	Retroprojetor
ATA343284A (de)	1991-10-15	Raffrollo
BR8400552A (pt)	1984-09-18	Toca-fitas
ATA454783A (de)	1984-07-15	Lusterbehang
ATA95483A (de)	1985-05-15	Waelzmuehle
ATA86284A (de)	1988-06-15	Loipenspursetzgeraet
AT386759B (de)	1988-10-10	Schlagmuehle
DK571984D0 (da)	1984-11-30	Skovhoester
BR8405756A (pt)	1985-02-20	Artropodicidas
ATA97784A (de)	1987-07-15	Geraeuschgedaempftes schienenrad
ATA312084A (de)	1990-07-15	Bandsaatschar
DD219060A3 (de)	1985-02-20	Absorptionswaermepumpe
DD232186A5 (de)	1986-01-22	Schaedlingsbekaempfungsmittel
DD253926A3 (de)	1988-02-10	Bohrlocherweiterer
FI830519A0 (fi)	1983-02-16	Dubbelviraformare
BR8304310A (pt)	1985-03-19	Peteca
BR8306841A (pt)	1985-07-16	Pentaoubos
BR6301363U (pt)	1985-04-30	Potenciostato-galvanostato
BR8306904A (pt)	1985-07-23	Metanizador
BR8307309A (pt)	1985-08-06	Fiodentalizador
BR8306637A (pt)	1985-07-09	Motodinamico
BR8304824A (pt)	1985-04-09	Divisoria

Legal Events

Date	Code	Title	Description
1991-09-09	AHS	Application shelved for other reasons than non-payment