DK472186D0 - Pyrido (2,3-d) pyrimidin derivater - Google Patents

Pyrido (2,3-d) pyrimidin derivater

Info

Publication number: DK472186D0
Authority: DK; Denmark
Prior art keywords: pyrido; pyrimidin; benzoyl; hydroxy; amino
Prior art date: 1985-03-08

Application number

DK472186A

Other languages

English (en)

Other versions

DK472186A (da

DK168666B1 (da

Inventor

Edward C Taylor

George Peter Beardsley

Peter J Harrington

Stephen R Fletcher

Original Assignee

Univ Princeton

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-03-08

Filing date

1986-10-02

Publication date

1986-10-02

1986-10-02 Application filed by Univ Princeton filed Critical Univ Princeton

1986-10-02 Publication of DK472186D0 publication Critical patent/DK472186D0/da

1986-12-19 Publication of DK472186A publication Critical patent/DK472186A/da

1994-05-16 Application granted granted Critical

1994-05-16 Publication of DK168666B1 publication Critical patent/DK168666B1/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Cosmetics (AREA)

DK472186A 1985-03-08 1986-10-02 5,6,7,8-tetrahydropyrido[2,3-d]pyrimidinderivater, fremgangsmåde til deres fremstilling samt farmaceutiske præparater indeholdende disse DK168666B1 (da)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US70962285A	1985-03-08	1985-03-08
US70962285		1985-03-08
US8600368		1986-02-24
PCT/US1986/000368 WO1986005181A1 (en)	1985-03-08	1986-02-24	PYRIDO AD2,3-d BDPYRIMIDIN DERIVATIVES

Publications (3)

Publication Number	Publication Date
DK472186D0 true DK472186D0 (da)	1986-10-02
DK472186A DK472186A (da)	1986-12-19
DK168666B1 DK168666B1 (da)	1994-05-16

Family

ID=24850641

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK472186A DK168666B1 (da)	1985-03-08	1986-10-02	5,6,7,8-tetrahydropyrido[2,3-d]pyrimidinderivater, fremgangsmåde til deres fremstilling samt farmaceutiske præparater indeholdende disse

Country Status (22)

Country	Link
EP (1)	EP0215063B1 (da)
JP (2)	JPH0822860B2 (da)
KR (1)	KR940002952B1 (da)
CN (1)	CN1016174B (da)
AT (1)	ATE96790T1 (da)
AU (1)	AU578813B2 (da)
CA (1)	CA1276637C (da)
DE (1)	DE3689250T2 (da)
DK (1)	DK168666B1 (da)
EG (1)	EG18371A (da)
ES (2)	ES8704167A1 (da)
GR (1)	GR860592B (da)
HU (1)	HU196202B (da)
IE (1)	IE63653B1 (da)
IL (1)	IL78059A (da)
MX (1)	MX9203357A (da)
NZ (1)	NZ215404A (da)
PH (1)	PH23136A (da)
PT (1)	PT82149B (da)
SU (1)	SU1676449A3 (da)
WO (1)	WO1986005181A1 (da)
ZA (1)	ZA861235B (da)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ219971A (en) *	1986-06-06	1989-08-29	Univ Princeton	Tetrahydropyrido (2,3-d pyrimidine derivatives and pharmaceutical compositions
IE60038B1 (en) *	1986-06-30	1994-05-18	Univ Princeton	4(3H)-oxo-5, 6, 7, 8-tetrahydropyrido-[2, 3-d]pyrimidine derivatives
US4818819A (en) *	1986-10-20	1989-04-04	The Trustees Of Princeton University	Process for the preparation of fused pyridine compounds
GB8702758D0 (en) *	1987-02-06	1987-03-11	Wellcome Found	Treatment of disease
AU598093B2 (en) *	1987-02-07	1990-06-14	Wellcome Foundation Limited, The	Pyridopyrimidines, methods for their preparation and pharmaceutical formulations thereof
EP0305667A3 (en) *	1987-09-03	1989-10-25	American Cyanamid Company	Improved process for producing 5,10-dideaza-(5,6,7,8)-tetrahydrofolic acid
US4895946A (en) *	1987-10-26	1990-01-23	The Trustees Of Princeton University	Process for the preparation of fused pyridine compounds
US4889859A (en) *	1988-02-05	1989-12-26	The Trustees Of Princeton University	Pyrido[2,3-d]pyrimidine derivatives
DK172753B1 (da) *	1988-05-25	1999-06-28	Lilly Co Eli	N-(5,6,7,8-tetrahydropyrido[2,3--d]pyrimidin-6-yl-alkanoyl)-glutaminsyrederivater, deres anvendelse, farmaceutiske præparat
JPH03173890A (ja) *	1989-09-21	1991-07-29	Takeda Chem Ind Ltd	ピロロ［２，３―ｄ］ピリミジン誘導体，その製造法，用途及び中間体
CA2066898A1 (en) *	1991-04-29	1992-10-30	Chuan Shih	Pharmaceutical compounds
WO1993022312A1 (en) *	1992-04-29	1993-11-11	Sri International	Deazaaminopterins for treatment of inflammation
US5196424A (en) *	1992-03-24	1993-03-23	Eli Lilly And Company	N-[2-amino-4-substituted[[(pyrrollo or pyrido)[2,3-d]pyrimidinyl]-alkyl]benzoyl]-L-glutamic acids
WO1993020075A1 (en) *	1992-04-01	1993-10-14	The University Of Sydney	8-substituted-n5-deazapterins as antifolates
ZA932731B (en) *	1992-04-23	1994-10-19	Lilly Co Eli	Method of treating gar-transformylase-dependent tumors
US5594139A (en) *	1993-01-29	1997-01-14	Agouron Pharmaceuticals, Inc.	Processes for preparing antiproliferative garft-inhibiting compounds
NZ261497A (en) *	1993-01-29	1997-06-24	Agouron Pharma	2-[4-[2-(2-amino-4-oxo-3h-pyrido[5,4-b]n-hetring)-ring containing hydrocarbyl chain]-amido]-pentanedioic acid
RU2136686C1 (ru) *	1994-07-28	1999-09-10	Агурон Фармасьютикалз, Инк.	Производные глутаминовой кислоты (варианты), фармацевтическая композиция, способ ингибирования роста и пролиферации клеток, производные тиофенкарбоновой кислоты (варианты)
CN1053448C (zh) *	1994-07-28	2000-06-14	阿格罗尼制药公司	用作抗增殖药物及garft抑制剂的化合物
US5831100A (en) *	1995-06-07	1998-11-03	Agouron Pharmaceuticals, Inc.	Syntheses of optically pure compounds useful as GARFT inhibitors and their intermediates
NZ515598A (en)	1999-05-24	2004-05-28	Sankyo Co	Synergistic medicinal compositions containing anti-Fas antibody and a compound having a folate antagonistic activity or a dihydrofolate reductase inhibiting activity
EP2349274B1 (en)	2008-09-17	2025-04-09	Endocyte, Inc.	Folate receptor binding conjugates of antifolates
CN116333411B (zh) *	2023-05-29	2023-08-11	石家庄启宏新材料制品有限公司	一种阻燃eva保温材料及其制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4512992A (en) *	1980-06-13	1985-04-23	Burroughs Wellcome Co.	Treatment with dialkoxy pyridopyrimidine compounds
US4526964A (en) *	1982-01-11	1985-07-02	Southern Research Institute	2,4-Diamino-6-(hydroxymethyl)pyrido[2,3-d]pyrimidine
US4431805A (en) *	1981-09-25	1984-02-14	Southern Research Institute	Pyrido[2,3-d]-pyrimidines
US4536575A (en) *	1982-01-11	1985-08-20	Southern Research Institute	2-Amino-4(3H)-oxopyrido[2,3-d]pyrimidino
US4460591A (en) *	1982-08-26	1984-07-17	Sri International	8,10-Dideazaminopterins
US4532241A (en) *	1982-08-26	1985-07-30	Sri International	8,10-Dideazaminopterins
US4432981A (en) *	1982-11-05	1984-02-21	Sterling Drug Inc.	2-(Pyridinyl or hydroxyphenyl)-8-substituted pyrido[2,3-d]pyrimidin-5(8H)-ones
EP0166726B1 (en) *	1983-12-27	1988-11-17	Sri International	10-ethyl-8,10-dideazaminopterins

1986
- 1986-02-19 ZA ZA861235A patent/ZA861235B/xx unknown
- 1986-02-24 WO PCT/US1986/000368 patent/WO1986005181A1/en not_active Ceased
- 1986-02-24 AU AU55108/86A patent/AU578813B2/en not_active Ceased
- 1986-02-24 HU HU862011A patent/HU196202B/hu not_active IP Right Cessation
- 1986-02-24 EP EP86901675A patent/EP0215063B1/en not_active Expired - Lifetime
- 1986-02-24 DE DE86901675T patent/DE3689250T2/de not_active Expired - Fee Related
- 1986-02-24 JP JP61501296A patent/JPH0822860B2/ja not_active Expired - Fee Related
- 1986-02-24 KR KR1019860700771A patent/KR940002952B1/ko not_active Expired - Fee Related
- 1986-02-24 AT AT86901675T patent/ATE96790T1/de not_active IP Right Cessation
- 1986-03-03 GR GR860592A patent/GR860592B/el unknown
- 1986-03-03 IE IE56186A patent/IE63653B1/en not_active IP Right Cessation
- 1986-03-05 ES ES552684A patent/ES8704167A1/es not_active Expired
- 1986-03-06 IL IL78059A patent/IL78059A/xx unknown
- 1986-03-06 EG EG107/86A patent/EG18371A/xx active
- 1986-03-06 PT PT82149A patent/PT82149B/pt not_active IP Right Cessation
- 1986-03-07 CA CA000503509A patent/CA1276637C/en not_active Expired - Lifetime
- 1986-03-07 PH PH33489A patent/PH23136A/en unknown
- 1986-03-07 NZ NZ215404A patent/NZ215404A/xx unknown
- 1986-03-08 CN CN86101475A patent/CN1016174B/zh not_active Expired
- 1986-10-02 DK DK472186A patent/DK168666B1/da not_active IP Right Cessation
- 1986-10-31 ES ES557174A patent/ES8801268A1/es not_active Expired
- 1986-11-03 SU SU864028461A patent/SU1676449A3/ru active
1992
- 1992-06-25 MX MX9203357A patent/MX9203357A/es unknown
1995
- 1995-09-05 JP JP7228382A patent/JPH08193084A/ja active Pending

Also Published As

Publication number	Publication date
CN86101475A (zh)	1987-01-21
DK472186A (da)	1986-12-19
ATE96790T1 (de)	1993-11-15
GR860592B (en)	1986-06-26
DK168666B1 (da)	1994-05-16
EG18371A (en)	1993-04-30
WO1986005181A1 (en)	1986-09-12
IL78059A (en)	1989-06-30
ZA861235B (en)	1986-10-29
JPH08193084A (ja)	1996-07-30
AU578813B2 (en)	1988-11-03
EP0215063A1 (en)	1987-03-25
ES8801268A1 (es)	1987-12-16
PH23136A (en)	1989-05-11
HU196202B (en)	1988-10-28
MX9203357A (es)	1992-07-01
NZ215404A (en)	1990-03-27
JPS62502535A (ja)	1987-10-01
AU5510886A (en)	1986-09-24
PT82149B (pt)	1988-04-21
EP0215063B1 (en)	1993-11-03
IL78059A0 (en)	1986-07-31
HUT41785A (en)	1987-05-28
CN1016174B (zh)	1992-04-08
ES557174A0 (es)	1987-12-16
EP0215063A4 (en)	1987-11-23
SU1676449A3 (ru)	1991-09-07
DE3689250D1 (de)	1993-12-09
KR940002952B1 (ko)	1994-04-09
IE63653B1 (en)	1995-05-31
CA1276637C (en)	1990-11-20
KR870700067A (ko)	1987-02-28
ES552684A0 (es)	1987-03-16
JPH0822860B2 (ja)	1996-03-06
ES8704167A1 (es)	1987-03-16
PT82149A (en)	1986-04-01
DE3689250T2 (de)	1994-03-03
IE860561L (en)	1986-09-08

Publication	Publication Date	Title
DK472186D0 (da)	1986-10-02	Pyrido (2,3-d) pyrimidin derivater
CA2031890A1 (en)	1991-06-12	N-(pyrrolo[2,3-d]pyrimidin-3-ylacyl)-glutamic acid derivatives
FI943948A7 (fi)	1994-08-26	Heterosykliset hiilihappojohdannaiset
FI961739L (fi)	1996-04-22	Amiinisuoloja klavulaanihapon valmistamiseksi
FI944305L (fi)	1994-09-16	Pyrido(2,3-d)pyrimidiinijohdannaiset fosfodiesteraasi-inhibiittoreina
DE68911159D1 (de)	1994-01-20	Pyrido[2,3-d]pyrimidinderivate.
IL74645A0 (en)	1985-06-30	Furan,thiophene and pyrrole derivatives and their preparation
DE59510879D1 (de)	2004-04-29	Koordinatenmessung an Werkstücken mit Korrekturen von Beschleunigungen
ES2003828A6 (es)	1988-11-16	Mejoras introducidas en el objeto de la patente principal n 552684 por un procedimiento para la obtencion de derivados 4 1 (5,6,7,8-tetrahidropirido(2,3-d)pirimidin-6-il-alquil-2 benzoil de acido l-glutamico
AU1835988A (en)	1988-09-15	New derivatives of substituted pyridine-3-carboxylic acid and use thereof
FI941712A0 (fi)	1994-04-13	Heterosykliset iminobismetyleenibisfosfonihappojohdannaiset
HUT40127A (en)	1986-11-28	Process for preparing new pyrido/2,3-d/pyrimidine derivatives and pharmaceutical compositions containing thereof
ES2113851T3 (es)	1998-05-16	Sales cristalinas estables y muy hidrosolubles antivirales de 2',3'-didesoxiinoxina monohidrato, 2',3'-didesoxi-2',3'-didehidrotimidina monohidrato y 2',3'-didesoxi-2'-fluoroinosina hemihidrato.
JPS5323993A (en)	1978-03-06	7-(n-substituted-2-phenylglycineamido)-3-substituted-3-cephem-4-caroxyli acids
AU581834B2 (en)	1989-03-02	5-chloro-5-triazolo``4,3-A``pyridine-7-carboxylic acids, useful as antiallergic agents
KR890023417U (ko)	1989-12-02	표적지의 수신용 콘트롤러의 회토접속장치
GB2179657B (en)	1989-08-09	Ethoxylated amino derivatives useful as levelling agents
ITMI920855V0 (it)	1992-09-25	Strumento per il rilevamento di sagome piane
GR861008B (en)	1986-08-11	Proccess for the preparation of heterocyclic amide derivatives
NO903994D0 (no)	1990-09-13	Fremgangsmaate for fremstilling av 5-aroyl-1,2-dihydro-3h-pyrrolo-(1,2-a)-pyrrol-1-carboxylsyrer og alkylestere og salter derav.
IT8953523V0 (it)	1989-12-06	Dispositivo di raccordo perfezionato per l'alimentazione di un iniettore
GB8522081D0 (en)	1985-10-09	Pyrido(1 2-a)pyrimidine derivatives
BR1101026A (pt)	2000-08-01	Derivados de ácido n-(5,6,7,8-tetraidropirido[2,3-d]pirimidin-6-iletil-tienil e furilcarbonil) glutâmico

Legal Events

Date	Code	Title	Description
1994-05-16	B1	Patent granted (law 1993)
2005-10-03	PBP	Patent lapsed	Country of ref document: DK