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DK464288D0 - Carbamoylpyrrolidonderivater - Google Patents

Carbamoylpyrrolidonderivater

Info

Publication number
DK464288D0
DK464288D0 DK464288A DK464288A DK464288D0 DK 464288 D0 DK464288 D0 DK 464288D0 DK 464288 A DK464288 A DK 464288A DK 464288 A DK464288 A DK 464288A DK 464288 D0 DK464288 D0 DK 464288D0
Authority
DK
Denmark
Prior art keywords
methoxy
halogen
methyl group
phenyl
optionally substituted
Prior art date
Application number
DK464288A
Other languages
English (en)
Other versions
DK464288A (da
Inventor
Hiromu Matsumura
Toshisada Yano
Akira Matsushita
Masami Eigyo
Original Assignee
Shionogi & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi & Co filed Critical Shionogi & Co
Publication of DK464288D0 publication Critical patent/DK464288D0/da
Publication of DK464288A publication Critical patent/DK464288A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
    • C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK464288A 1987-08-19 1988-08-18 Carbamoylpyrrolidonderivater DK464288A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP20595687 1987-08-19

Publications (2)

Publication Number Publication Date
DK464288D0 true DK464288D0 (da) 1988-08-18
DK464288A DK464288A (da) 1989-02-20

Family

ID=16515486

Family Applications (1)

Application Number Title Priority Date Filing Date
DK464288A DK464288A (da) 1987-08-19 1988-08-18 Carbamoylpyrrolidonderivater

Country Status (9)

Country Link
US (2) US4977167A (da)
EP (1) EP0304330B1 (da)
KR (1) KR900006990B1 (da)
AT (1) ATE103592T1 (da)
AU (1) AU612170B2 (da)
CA (1) CA1305148C (da)
DE (1) DE3888756T2 (da)
DK (1) DK464288A (da)
ES (1) ES2061663T3 (da)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5229402A (en) * 1988-04-15 1993-07-20 Taiho Pharmaceutical Company, Ltd. Carbamoyl-2-pyrrolidinone compounds
JP2803882B2 (ja) * 1990-02-20 1998-09-24 日清製粉株式会社 １―フエノキシカルボニル―２―ピロリジノン誘導体
US5149817A (en) * 1990-03-05 1992-09-22 Shionogi & Co., Ltd. Teirahydropyridine derivatives
US5243051A (en) * 1990-03-05 1993-09-07 Shionigi & Co., Ltd. Tetrahydropyridine derivatives
JP2807577B2 (ja) * 1990-06-15 1998-10-08 エーザイ株式会社 環状アミド誘導体
ZA918221B (en) * 1990-10-23 1992-06-24 Akzo Nv 4-(4-or 6-(trifluoromethyl-2-pyridinyl))-1-piperazinyl-alkyl substituted lactams
JP3038032B2 (ja) * 1991-03-25 2000-05-08 日清製粉株式会社 血小板凝集抑制薬
US5153316A (en) * 1991-06-04 1992-10-06 Crouse Gary D Intermediates for herbicidal phenylimidazolones
CA2100641A1 (en) * 1992-07-23 1994-01-24 Hiromu Matsumura Novel piperidine derivatives and process for preparation thereof
FR2703354B1 (fr) * 1993-03-31 1995-06-30 Lafon Labor Derives de 1, 2, 5, 6-tetrahydropyridine, leur procede de preparation et leurs applications en therapeutique.
JP3719612B2 (ja) * 1993-06-14 2005-11-24 塩野義製薬株式会社 ヘテロ環を含有する尿素誘導体
EP0937065A1 (en) * 1996-10-31 1999-08-25 Novo Nordisk A/S Constrained somatostatin agonists and antagonists
SE0004780D0 (sv) 2000-12-22 2000-12-22 Jordanian Pharmaceutical Mfg & Novel compunds
ATE445838T1 (de) 2001-07-25 2009-10-15 Raptor Pharmaceutical Inc Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
US6727277B1 (en) 2002-11-12 2004-04-27 Kansas State University Research Foundation Compounds affecting cholesterol absorption
CA2789097C (en) 2005-04-28 2017-02-21 Proteus Digital Health, Inc. Pharma-informatics system
JP2010503710A (ja) 2006-09-18 2010-02-04 ラプトール ファーマシューティカル インコーポレイテッド 受容体関連タンパク質（ｒａｐ）結合体の投与による肝障害の処置
NZ616673A (en) 2009-02-20 2014-08-29 To Bbb Holding B V Glutathione-based drug delivery system
ES2942923T3 (es) 2009-05-06 2023-06-07 Laboratory Skin Care Inc Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas
CA2764038A1 (en) 2009-05-29 2010-12-02 The Trustees Of Columiba University In The City Of New York Modulation of phospholipase d for the treatment of neurodegenerative disorders
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
ES2734268T3 (es) * 2012-10-11 2019-12-05 Southern Res Inst Derivados de urea y amida de aminoalquilpiperazinas y uso de los mismos
CN103360337B (zh) * 2013-07-11 2016-04-27 浙江海蓝化工集团有限公司 一种2-巯基-5-甲基-1,3,4-噻二唑的制备方法
US20170267706A1 (en) * 2014-08-19 2017-09-21 Straitmark Holding Ag Method for the synthesis of heterocyclic hydrogen phosphine oxide
EP3506983B1 (en) * 2016-09-01 2021-08-25 Mebias Discovery, Inc. Substituted urea-derivatives for the treatment of pain
US11014905B2 (en) * 2017-03-13 2021-05-25 Sumitomo Dainippon Pharma Co., Ltd. 2,6-disubstituted pyridine derivative

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2829146A (en) * 1956-07-30 1958-04-01 Monsanto Chemicals Pyrrolidine compounds
IT1045043B (it) * 1975-08-13 1980-04-21 Isf Spa Derivati pirrolidinici
BE864269A (fr) * 1977-03-03 1978-06-16 Parke Davis & Co Nouveaux n-(aminoalkyl substitue)-2-oxo-1-pyrrolidine-acetamides et procedes pour les produire
CU21107A3 (es) * 1978-02-10 1988-02-01 Hoffmann La Roche Pyrrolidines derivatives
EP0089900B1 (en) * 1982-03-24 1985-12-27 Prodes S.A. New n-((2-oxo-1-pyrrolidinyl)acetyl)piperazines, the methods of producing such new compounds and their salts as well as pharmaceutical preparations for therapeutic use containing these compounds or salts
DE3420193A1 (de) * 1984-05-30 1985-12-05 Boehringer Ingelheim KG, 6507 Ingelheim Neue substituierte pyrrolidinone, verfahren zu ihrer herstellung und arzneimittel
IT1224168B (it) * 1986-08-01 1990-09-26 Finanziaria R F Spa Ora Finanz Derivati del pirrolidin-2-one ad attivita' nootropa
US4791112A (en) * 1987-02-02 1988-12-13 The Boc Group, Inc. N-heterocyclic-N-(4-piperidyl)amides and pharmaceutical compositions and methods employing such compounds

Also Published As

Publication number Publication date
AU2104388A (en) 1989-03-23
CA1305148C (en) 1992-07-14
EP0304330B1 (en) 1994-03-30
DE3888756T2 (de) 1994-07-14
DK464288A (da) 1989-02-20
ES2061663T3 (es) 1994-12-16
KR890003742A (ko) 1989-04-17
US4977167A (en) 1990-12-11
EP0304330A1 (en) 1989-02-22
US5120733A (en) 1992-06-09
KR900006990B1 (ko) 1990-09-25
DE3888756D1 (de) 1994-05-05
ATE103592T1 (de) 1994-04-15
AU612170B2 (en) 1991-07-04

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment