DK455789D0 - Polypeptid - Google Patents
PolypeptidInfo
- Publication number
- DK455789D0 DK455789D0 DK455789A DK455789A DK455789D0 DK 455789 D0 DK455789 D0 DK 455789D0 DK 455789 A DK455789 A DK 455789A DK 455789 A DK455789 A DK 455789A DK 455789 D0 DK455789 D0 DK 455789D0
- Authority
- DK
- Denmark
- Prior art keywords
- sod
- variants
- pct
- recombinant
- amino acid
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
- 102100027186 Extracellular superoxide dismutase [Cu-Zn] Human genes 0.000 abstract 8
- 108700001268 Extracellular superoxide dismutase [Cu-Zn] Proteins 0.000 abstract 8
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 3
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 abstract 1
- 108020004511 Recombinant DNA Proteins 0.000 abstract 1
- OUUQCZGPVNCOIJ-UHFFFAOYSA-M Superoxide Chemical compound [O-][O] OUUQCZGPVNCOIJ-UHFFFAOYSA-M 0.000 abstract 1
- 102000019197 Superoxide Dismutase Human genes 0.000 abstract 1
- 108010012715 Superoxide dismutase Proteins 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 210000004899 c-terminal region Anatomy 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 229960002897 heparin Drugs 0.000 abstract 1
- 229920000669 heparin Polymers 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000002035 prolonged effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0089—Oxidoreductases (1.) acting on superoxide as acceptor (1.15)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Materials For Medical Uses (AREA)
Priority Applications (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK455789A DK455789D0 (da) | 1989-09-15 | 1989-09-15 | Polypeptid |
| IL95701A IL95701A0 (en) | 1989-09-15 | 1990-09-14 | Polypeptide having superoxide dismutating property |
| AT90914512T ATE146219T1 (de) | 1989-09-15 | 1990-09-17 | Polypeptid |
| EP90914512A EP0593435B1 (en) | 1989-09-15 | 1990-09-17 | A polypeptide |
| AU64441/90A AU6444190A (en) | 1989-09-15 | 1990-09-17 | A polypeptide |
| US07/856,077 US5366729A (en) | 1989-09-15 | 1990-09-17 | Non-glycosylated variants of extracellular superoxide dismutase (EC-SOD) |
| DE69029406T DE69029406D1 (en) | 1989-09-15 | 1990-09-17 | Polypeptid |
| PCT/DK1990/000238 WO1991004315A1 (en) | 1989-09-15 | 1990-09-17 | A polypeptide |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK455789A DK455789D0 (da) | 1989-09-15 | 1989-09-15 | Polypeptid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK455789D0 true DK455789D0 (da) | 1989-09-15 |
Family
ID=8134617
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK455789A DK455789D0 (da) | 1989-09-15 | 1989-09-15 | Polypeptid |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US5366729A (da) |
| EP (1) | EP0593435B1 (da) |
| AT (1) | ATE146219T1 (da) |
| AU (1) | AU6444190A (da) |
| DE (1) | DE69029406D1 (da) |
| DK (1) | DK455789D0 (da) |
| WO (1) | WO1991004315A1 (da) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5843641A (en) * | 1993-02-26 | 1998-12-01 | Massachusetts Institute Of Technology | Methods for the daignosis, of familial amyotrophic lateral sclerosis |
| EP0627486A1 (en) * | 1993-06-04 | 1994-12-07 | N.V. Innogenetics S.A. | New extracellular superoxide dismutase, a process for preparing the same and compositions containing the same |
| DK75393D0 (da) * | 1993-06-24 | 1993-06-24 | Symbicom Ab | Production of protein |
| US6127356A (en) | 1993-10-15 | 2000-10-03 | Duke University | Oxidant scavengers |
| US5994339A (en) * | 1993-10-15 | 1999-11-30 | University Of Alabama At Birmingham Research Foundation | Oxidant scavengers |
| US5747026A (en) * | 1993-10-15 | 1998-05-05 | University Of Alabama At Birmingham Research Foundation | Antioxidants |
| WO1996009053A1 (en) * | 1994-09-20 | 1996-03-28 | Duke University | Oxidoreductase activity of manganic porphyrins |
| JPH08208511A (ja) * | 1995-01-31 | 1996-08-13 | Samu Kenkyusho:Kk | 抗運動ニューロン疾患剤 |
| DE69635304T2 (de) * | 1995-06-07 | 2006-07-20 | Duke University | Faenger fuer oxidantien |
| AU769217B2 (en) * | 1995-06-07 | 2004-01-22 | Duke University | Oxidant scavengers |
| JP2001521939A (ja) | 1997-11-03 | 2001-11-13 | デューク・ユニバーシティー | 置換されたポルフィリン類 |
| ATE311206T1 (de) | 1998-04-24 | 2005-12-15 | Univ Duke | Substituierte porphyrine |
| US6190658B1 (en) | 1998-05-08 | 2001-02-20 | Webb-Waring Institute For Biomedical Research | Genetically modified manganese superoxide dismutase for treating oxidative damage |
| NZ513164A (en) | 1999-01-25 | 2006-03-31 | Nat Jewish Med & Res Center | Substituted porphyrins |
| FR2805821B1 (fr) * | 2000-03-01 | 2004-01-16 | Diatos | Sequences d'acides amines facilitant la penetration d'une substance d'interet a l'interieur des cellules et/ou des noyaux cellulaires |
| US8003595B2 (en) | 2000-03-01 | 2011-08-23 | Cellectis | Amino acid sequences facilitating penetration of a substance of interest into cells and/or cell nuclei |
| EP1392328B1 (en) * | 2001-01-19 | 2009-08-12 | National Jewish Medical and Research Center | Medicament for protection in radiotherapy |
| FI20010898A0 (fi) * | 2001-04-30 | 2001-04-30 | Ylae Herttuala Seppo | Ekstrasellulaarinen superoksididismutaasi (EC-SOD) geeniterapia restenoosoin ehkäisemiseksi |
| FI116851B (fi) | 2001-05-03 | 2006-03-15 | Fit Biotech Oyj Plc | Ilmentämisvektori, sen käyttöjä ja menetelmä sen valmistamiseksi sekä sitä sisältäviä tuotteita |
| WO2002098431A1 (en) | 2001-06-01 | 2002-12-12 | National Jewish Medical And Research Center | Oxidant scavengers for treatment of diabetes or use in transplantation or induction of immune tolerance |
| WO2002100293A2 (en) * | 2001-06-13 | 2002-12-19 | Webb-Waring Institute For Biomedical Research | A diagnostic and prognostic method for evaluating ocular inflammation and oxidative stress and the treatment of the same |
| WO2003103680A1 (en) * | 2002-06-07 | 2003-12-18 | Duke University | Substituted porphyrins |
| BRPI0413521A (pt) | 2003-08-14 | 2006-10-10 | Diatos | seqüências de aminoácidos que facilitam a penetração de uma substáncia de interesse nas células e/ou no núcleos celulares |
| US8318803B2 (en) * | 2003-10-31 | 2012-11-27 | Tae-Yoon Kim | EC SOD and use thereof |
| EP1692187B1 (en) * | 2003-10-31 | 2012-06-27 | Tae-Yoon Kim | EC SOD and cell transducing EC SOD and use thereof |
| US7332159B2 (en) | 2004-09-30 | 2008-02-19 | Board Of Regents Of The University Of Nebraska | Method and composition for inhibiting reperfusion injury in the brain |
| ES2600469T3 (es) | 2008-05-23 | 2017-02-09 | National Jewish Health | Un compuesto para su uso en el tratamiento de lesiones asociadas con la exposición al gas fosgeno o al gas de cloro |
| US8465413B2 (en) | 2010-11-25 | 2013-06-18 | Coloplast A/S | Method of treating Peyronie's disease |
| WO2019195387A1 (en) * | 2018-04-03 | 2019-10-10 | Cornell University | Gene therapy for oxidative stress |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK145950C (da) * | 1979-05-17 | 1983-09-26 | Forenede Bryggerier As | Fremgangsmaade til isolering af cu,zn-superoxid-dismutase fra vandige oploesninger indeholdende dette enzym sammen med ledsagende proteiner |
| US4530901A (en) * | 1980-01-08 | 1985-07-23 | Biogen N.V. | Recombinant DNA molecules and their use in producing human interferon-like polypeptides |
| JPS5729285A (en) * | 1980-07-30 | 1982-02-17 | Takeda Chem Ind Ltd | Superoxide dismutase and its preparation |
| US4738927A (en) * | 1982-03-31 | 1988-04-19 | Ajinomoto Co. Inc. | Gene coded for interleukin-2 polypeptide, recombinant DNA carrying the said gene, a living cell line possessing the recombinant DNA, and method for producing interleukin-2 using the said cell |
| IT1150598B (it) * | 1982-12-14 | 1986-12-17 | Ines Bianchi | Procedimento per la purificazione della superossidodismutasi mediante cromatografia di affinita' |
| DE3485284D1 (de) * | 1983-10-03 | 1992-01-02 | Chiron Corp | Klonieren von superoxid-dismutase und expression in mikroorganismen. |
| US4742004A (en) * | 1984-08-27 | 1988-05-03 | Bio-Technology General Corp. | Method for producing enzymatically active eucaryotic sod in bacteria |
| JPS61111690A (ja) * | 1984-11-06 | 1986-05-29 | Ube Ind Ltd | 組換えｄｎａおよびその用途 |
| EP0213628A3 (en) * | 1985-09-03 | 1988-09-21 | Yeda Research And Development Company, Ltd. | Expression of superoxide dismutase in eukaryotic cells |
| DK402785D0 (da) * | 1985-09-03 | 1985-09-03 | Syn Tek Ab | Fremgangsmaade til fremstilling af et enzym |
| CA1289092C (en) * | 1987-01-15 | 1991-09-17 | Robert A. Hallewell | Thermostable human cu/zn superoxide dismutase muteins |
| DE69027383T2 (de) * | 1989-03-06 | 1996-11-14 | Masayasu Inoue | Neue superoxyd-dismutase |
-
1989
- 1989-09-15 DK DK455789A patent/DK455789D0/da not_active Application Discontinuation
-
1990
- 1990-09-17 WO PCT/DK1990/000238 patent/WO1991004315A1/en not_active Ceased
- 1990-09-17 AU AU64441/90A patent/AU6444190A/en not_active Abandoned
- 1990-09-17 US US07/856,077 patent/US5366729A/en not_active Expired - Fee Related
- 1990-09-17 AT AT90914512T patent/ATE146219T1/de not_active IP Right Cessation
- 1990-09-17 DE DE69029406T patent/DE69029406D1/de not_active Expired - Lifetime
- 1990-09-17 EP EP90914512A patent/EP0593435B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| WO1991004315A1 (en) | 1991-04-04 |
| EP0593435A1 (en) | 1994-04-27 |
| ATE146219T1 (de) | 1996-12-15 |
| DE69029406D1 (en) | 1997-01-23 |
| US5366729A (en) | 1994-11-22 |
| AU6444190A (en) | 1991-04-18 |
| EP0593435B1 (en) | 1996-12-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHS | Application shelved for other reasons than non-payment |