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DK445078A - Fremgangsmaade til fremstilling af 4,5-dihydro-2-alkoxycarbonylamino-5-carbocyklisk arylimidazoler og derivater deraf - Google Patents

Fremgangsmaade til fremstilling af 4,5-dihydro-2-alkoxycarbonylamino-5-carbocyklisk arylimidazoler og derivater deraf

Info

Publication number
DK445078A
DK445078A DK445078A DK445078A DK445078A DK 445078 A DK445078 A DK 445078A DK 445078 A DK445078 A DK 445078A DK 445078 A DK445078 A DK 445078A DK 445078 A DK445078 A DK 445078A
Authority
DK
Denmark
Prior art keywords
alcoxycarbonylamino
arylimidazoles
carbocyclic
dihydro
derivatives
Prior art date
Application number
DK445078A
Other languages
English (en)
Inventor
C A Dvorak
C C Beard
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of DK445078A publication Critical patent/DK445078A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44Nitrogen atoms not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/24Y being a hetero atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/63Esters of sulfonic acids
    • C07C309/64Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms
    • C07C309/69Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms of a carbon skeleton substituted by nitrogen atoms, not being part of nitro or nitroso groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/58Radicals substituted by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK445078A 1977-10-07 1978-10-06 Fremgangsmaade til fremstilling af 4,5-dihydro-2-alkoxycarbonylamino-5-carbocyklisk arylimidazoler og derivater deraf DK445078A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/840,336 US4172204A (en) 1977-10-07 1977-10-07 Method for preparing 4,5-dihydro-2-alkoxycarbonylamino-5-carbocyclic aryl imidazoles and intermediates thereof

Publications (1)

Publication Number Publication Date
DK445078A true DK445078A (da) 1979-04-08

Family

ID=25282075

Family Applications (1)

Application Number Title Priority Date Filing Date
DK445078A DK445078A (da) 1977-10-07 1978-10-06 Fremgangsmaade til fremstilling af 4,5-dihydro-2-alkoxycarbonylamino-5-carbocyklisk arylimidazoler og derivater deraf

Country Status (9)

Country Link
US (1) US4172204A (da)
EP (1) EP0001500A1 (da)
JP (1) JPS5461178A (da)
DK (1) DK445078A (da)
ES (1) ES474035A1 (da)
FI (1) FI783033A7 (da)
IL (1) IL55676A0 (da)
IT (1) IT7869316A0 (da)
PL (1) PL210061A1 (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4709094A (en) * 1986-07-10 1987-11-24 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon Sigma brain receptor ligands and their use
US5312840A (en) * 1986-07-10 1994-05-17 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education Substituted guanidines having high binding to the sigma receptor and the use thereof
US5385946A (en) * 1986-07-10 1995-01-31 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon Method for treating hypertension with disubstituted granidine compounds
PT96930B (pt) 1990-03-02 1998-06-30 Univ Oregon Metodo para a utilizacao de guanidinas tri- e tetra-substituidas como antagonistas de amino-acidos excitadores
US5262568A (en) * 1990-03-02 1993-11-16 State Of Oregon Tri- and tetra-substituted guanidines and their use as excitatory amino acid antagonists
JPH05508836A (ja) * 1990-05-25 1993-12-09 オレゴン州 シグマ受容体に対して高い結合性を有する置換グアニジンおよびその使用
IE20030530A1 (en) * 1991-02-08 2003-10-01 Cambridge Neuroscience Inc Guanidines and derivatives
US5741661A (en) * 1991-02-08 1998-04-21 Cambridge Neuroscience, Inc. Substituted guanidines and derivatives thereof as modulators of neurotransmitter release and novel methodology for identifying neurotransmitter release blockers
US5847006A (en) * 1991-02-08 1998-12-08 Cambridge Neuroscience, Inc. Therapeutic guanidines
WO1994027591A1 (en) * 1993-05-27 1994-12-08 Cambridge Neuroscience, Inc. Therapeutic substituted guanidines
EP0739200A4 (en) * 1993-11-23 1997-12-17 Cambridge Neuroscience Inc SUBSTITUTED GUANIDINES FOR THERAPEUTIC USE
JPH09509156A (ja) 1994-02-03 1997-09-16 ケンブリッジ・ニューロサイエンス・インコーポレーテッド 治療用グアニジン類
US6143791A (en) * 1994-02-03 2000-11-07 Cambridge Neuroscience, Inc. Therapeutic guanidines
US6787569B1 (en) 1994-02-03 2004-09-07 Cambridge Neuroscience, Inc. Therapeutic guanidines
US7351743B1 (en) 1994-02-03 2008-04-01 Wyeth Therapeutic guanidines

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL38933A0 (en) * 1971-03-17 1972-05-30 Ciba Geigy Ag New carbamates,their manufacture and their use in plant protection
DE2149245A1 (de) 1971-10-02 1973-04-05 Riedel De Haen Ag 4-phenylimidazolderivate
US4080335A (en) * 1975-07-28 1978-03-21 Beecham Group Limited Anorexic chromans
US4088771A (en) * 1976-07-26 1978-05-09 Syntex (U.S.A.) Inc. 1-Lower alkyl-4,5-dihydro-5-phenyl-2-lower alkoxy carbonylaminoimidazoles and substituted phenyl derivatives thereof
US4110463A (en) * 1977-06-03 1978-08-29 Syntex (U.S.A.) Inc. Imidazole-2-carbamates

Also Published As

Publication number Publication date
FI783033A7 (fi) 1979-04-08
US4172204A (en) 1979-10-23
PL210061A1 (da) 1980-01-14
JPS5461178A (en) 1979-05-17
IT7869316A0 (it) 1978-10-05
IL55676A0 (en) 1978-12-17
EP0001500A1 (en) 1979-04-18
ES474035A1 (es) 1979-05-01

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