[go: up one dir, main page]

DK436981A - Fremgangsmaade til fremstilling af 25-hydroxy26,26,26,27,27,27,-hexafluor-cholecalciferol og mellemprodukter herved - Google Patents

Fremgangsmaade til fremstilling af 25-hydroxy26,26,26,27,27,27,-hexafluor-cholecalciferol og mellemprodukter herved

Info

Publication number
DK436981A
DK436981A DK436981A DK436981A DK436981A DK 436981 A DK436981 A DK 436981A DK 436981 A DK436981 A DK 436981A DK 436981 A DK436981 A DK 436981A DK 436981 A DK436981 A DK 436981A
Authority
DK
Denmark
Prior art keywords
hydroxy26
hexafluor
cholecalciferol
intermediates
preparing
Prior art date
Application number
DK436981A
Other languages
English (en)
Inventor
H F Deluca
Y Tanaka
N Ikekawa
Y Kobayashi
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Publication of DK436981A publication Critical patent/DK436981A/da
Priority to DK375484A priority Critical patent/DK375484A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
DK436981A 1980-02-04 1981-10-02 Fremgangsmaade til fremstilling af 25-hydroxy26,26,26,27,27,27,-hexafluor-cholecalciferol og mellemprodukter herved DK436981A (da)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DK375484A DK375484A (da) 1980-02-04 1984-08-02 3-hydroxy-26,26,26,27,27,27-hexafluor-cholest-5-en-25-ol-forbindelserog fremgangsmaade til fremstilling deraf

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/118,149 US4248791A (en) 1980-02-04 1980-02-04 25-Hydroxy-26,26,26,27,27,27-hexafluorocholecalciferol
PCT/US1981/000035 WO1981002298A1 (en) 1980-02-04 1981-01-13 Ciferol 25-hydroxy-26,26,26,27,27,27-hexafluorocholecalciferol

Publications (1)

Publication Number Publication Date
DK436981A true DK436981A (da) 1981-10-02

Family

ID=22376765

Family Applications (1)

Application Number Title Priority Date Filing Date
DK436981A DK436981A (da) 1980-02-04 1981-10-02 Fremgangsmaade til fremstilling af 25-hydroxy26,26,26,27,27,27,-hexafluor-cholecalciferol og mellemprodukter herved

Country Status (12)

Country Link
US (1) US4248791A (da)
AU (1) AU544294B2 (da)
BE (1) BE887344A (da)
CH (2) CH652725A5 (da)
DK (1) DK436981A (da)
FR (1) FR2477145B1 (da)
GB (2) GB2068382B (da)
IE (1) IE50815B1 (da)
IL (1) IL61930A (da)
IT (1) IT1194789B (da)
NZ (1) NZ196039A (da)
WO (1) WO1981002298A1 (da)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4248791A (en) * 1980-02-04 1981-02-03 Wisconsin Alumni Research Foundation 25-Hydroxy-26,26,26,27,27,27-hexafluorocholecalciferol
US4358406A (en) * 1981-07-27 1982-11-09 Wisconsin Alumni Research Foundation 26,26,26,27,27,27-Hexafluoro-1α,25-dihydroxycholecalciferol and process for preparing same
US4411833A (en) * 1982-05-26 1983-10-25 Wisconsin Alumni Research Foundation Method for preparing 26,26,26,27,27,27-hexafluoro-1α,25-dihydroxycholesterol
JPS59500864A (ja) * 1982-05-26 1984-05-17 ウイスコンシン　アラムナイ　リサ−チ　フオンデ−シヨン ２６，２６．２６，２７．２７，２７―ヘキサフルオロ―１α，２５―ジヒドロキシコレステロール化合物及びその製造方法
US4613594A (en) * 1984-11-16 1986-09-23 Hoffmann-La Roche Inc. Fluorinated vitamin D3 compounds
ZA859138B (en) * 1984-12-19 1986-08-27 Hoffmann La Roche Cholecalciferol derivatives
EP0205025A1 (en) * 1985-05-27 1986-12-17 Sumitomo Pharmaceuticals Company, Limited Fluorine derivatives of vitamin D3 and cell differentiation-inducing agents containing the same as an active ingredient
JPH0764804B2 (ja) * 1986-04-25 1995-07-12 住友製薬株式会社 活性型ビタミンｄ３のフッ素誘導体
CA1314872C (en) 1986-04-25 1993-03-23 Toshio Nishizawa Fluorine derivatives of vitamin d _and process for producing the same
US4853378A (en) * 1986-10-20 1989-08-01 Sumitomo Chemical Company, Limited Fluorine derivatives of vitamin D3 and process for producing the same
JPS63196556A (ja) * 1987-02-10 1988-08-15 Taisho Pharmaceut Co Ltd 含フツ素ビタミンｄ誘導体
JPH0737476B2 (ja) * 1991-01-17 1995-04-26 ウイスコンシン アラムナイ リサーチ フオンデーシヨン ２６，２６，２６，２７，２７，２７−ヘキサフルオロ−１α，２５−ジヒドロキシコレステロール
EP0684827A1 (en) * 1993-02-19 1995-12-06 Wisconsin Alumni Research Foundation USE OF 26,26,26,27,27,27-HEXAFLUORO-1$g(a),25-DIHYDROXYCHOLECALCIFEROL FOR THE TREATMENT OF CALCIUM METABOLISM DISORDERS
US5428029A (en) * 1993-11-24 1995-06-27 Hoffmann-La Roche Inc. Vitamin D3 fluorinated analogs
CN102341110B (zh) * 2009-01-27 2017-04-12 博格有限责任公司 用于减轻与化疗有关的副作用的维生素d3及其类似物
CN105663146B (zh) 2009-08-14 2020-09-11 博格有限责任公司 用于治疗脱发的维生素d3及其类似物
AU2010300539B9 (en) * 2009-10-02 2018-07-19 Wisconsin Alumni Research Foundation 1-desoxy-2-methylene-19-nor-vitamin D analogs and their uses
SG11201509715UA (en) 2013-05-29 2015-12-30 Berg Llc Preventing or mitigating chemotherapy induced alopecia using vitamin d
GB2581656A (en) * 2017-11-17 2020-08-26 Piraee Mahmood Combinations of lanosterol or 25-hydroxycholesterol including derivatives thereof useful in the treatment of lens disorders

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4069321A (en) * 1975-10-14 1978-01-17 Merck & Co., Inc. Blocked cholecalciferol and dihydrotachysterol 3 derivatives
US4196133A (en) * 1979-03-05 1980-04-01 Wisconsin Alumni Research Foundation 24,24-Difluoro-25-hydroxycholecalciferol
US4248791A (en) * 1980-02-04 1981-02-03 Wisconsin Alumni Research Foundation 25-Hydroxy-26,26,26,27,27,27-hexafluorocholecalciferol

Also Published As

Publication number Publication date
NZ196039A (en) 1983-07-15
GB2082586A (en) 1982-03-10
IT1194789B (it) 1988-09-28
BE887344A (fr) 1981-06-01
US4248791A (en) 1981-02-03
WO1981002298A1 (en) 1981-08-20
CH651295A5 (de) 1985-09-13
AU544294B2 (en) 1985-05-23
FR2477145A1 (fr) 1981-09-04
IE810196L (en) 1981-08-04
AU6684681A (en) 1981-08-13
IE50815B1 (en) 1986-07-23
IL61930A0 (en) 1981-02-27
CH652725A5 (de) 1985-11-29
IL61930A (en) 1984-11-30
GB2068382A (en) 1981-08-12
GB2082586B (en) 1983-10-05
FR2477145B1 (fr) 1985-09-20
GB2068382B (en) 1984-02-29
IT8119459A0 (it) 1981-02-02

Similar Documents

Publication Publication Date Title
DK516182A (da) Fremgangsmaade til fremstilling af 3-hydroxy-ml-236b derivater, betegnet m-4 og m-4'
DK280182A (da) Fremgangsmaade til fremstilling af n-aryl-piperazinalkanamider
DK217782A (da) Tastatur og fremgangsmaade til fremstilling af dette
DK529479A (da) Fremgangsmaade og apparat til stoerkning af metal
DK436981A (da) Fremgangsmaade til fremstilling af 25-hydroxy26,26,26,27,27,27,-hexafluor-cholecalciferol og mellemprodukter herved
DK143491D0 (da) Fremgangsmaade til fremstilling af 3-oen-phenylacetylaminopiperidinaa-2,6-dion
DK32684D0 (da) Fremgangsmade til fremstilling af 26,26,26,27,27,27-hexafluorlalfa,25-dihydroxycholesterol og mellemprodukter til brug herfor
DK215490A (da) Fremgangsmaade til fremstilling af 10-substituerede 1,8-dihydroxy-9-anthroner
DK25580A (da) Fremgangsmaade til fremstilling af 2-substituerede trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1h-pyrido (4,3-b) indoler og mellemprodukter heraf
DK379985D0 (da) Fremgangsmaade til fremstilling af 6-chlor-n-methyl-2,3,4,5-tetrahydro-lh-benzazepin
DK370781A (da) Fremgangsmaade til fremstilling af 3,4-bis-phenyl-1,2,4-triazoler
DK157855C (da) Fremgangsmaade til fremstilling af 2,3-dichlor-5-trichlormethylpyridin
DK159158C (da) Fremgangsmaade til fremstilling af penicillanoyloxy-methylpenicillanat-1,1,1',1'-tetraoxid
DK159681A (da) Fremgangsmaade til fremstilling af 4,5-diaryl-alfa-(polyfluoralkyl)-1h-pyrrol-2-methanaminer
DK115581A (da) Fremgangsmaade til fremstilling af pyrimidylquinazoliner
DK370582A (da) Fremgangsmaade til fremstilling af 2-beta-d-ribofuranosylthiazol-4-carboxamid
DK350280A (da) Fremgangsmaade til fremstilling af 4,5-diaryl-alfapolyfluoralkyl-1h-pyrrol-2-methanoler og 1-(4,5-diaryl-1h-pyrrol-2-yl)-polyfluoralkanoner
DK316981A (da) Fremgangsmaade til fremstilling af pentapeptider
DK154207C (da) Fremgangsmaade til fremstilling af 1,8-dihydroxy-10-acyl-9-anthroner
DK283381A (da) Fremgangsmaade til fremstilling af 1,2,4-triazinylthiomethyl-3-cephem-sulfoxid
DK274882A (da) Fremgangsmaade til fremstilling af 4alfa,5alfa-epoxy-3,20-dioxopregnen-2alfa,16alfa-dicarbonitril og mellemprodukt herved
DK188881A (da) Fremgangsmaade til fremstilling af 2-guanidinthiazol-derivater
DK449881A (da) Fremgangsmaade til fremstilling af moroxydinphenoxyisobutyrater
DK127182A (da) Fremgangsmaade til fremstilling af 1,1-dioxopenicillanoyloxymethyl-6-(2-phenylacetamido)penicillanater og mellemprodukter herved
DK513580A (da) Fremgangsmaade til fremstilling af 4,5-diaryl-alfa (polyhalogenalkyl)-1h-imidazol-2-methanoler