DK4058437T3 - Matrix-metalloproteinase-(MMP)-inhibitorer og fremgangsmåder til anvendelse heraf - Google Patents
Matrix-metalloproteinase-(MMP)-inhibitorer og fremgangsmåder til anvendelse heraf Download PDFInfo
- Publication number
- DK4058437T3 DK4058437T3 DK20886710.1T DK20886710T DK4058437T3 DK 4058437 T3 DK4058437 T3 DK 4058437T3 DK 20886710 T DK20886710 T DK 20886710T DK 4058437 T3 DK4058437 T3 DK 4058437T3
- Authority
- DK
- Denmark
- Prior art keywords
- mmp
- inhibitors
- methods
- same
- matrix metalloproteinase
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/24—Metalloendopeptidases (3.4.24)
- C12Y304/24065—Macrophage elastase (3.4.24.65), i.e. metalloelastase
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962935358P | 2019-11-14 | 2019-11-14 | |
| PCT/US2020/060387 WO2021097190A1 (en) | 2019-11-14 | 2020-11-13 | Matrix metalloproteinase (mmp) inhibitors and methods of use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK4058437T3 true DK4058437T3 (da) | 2025-01-20 |
Family
ID=75912339
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK20886710.1T DK4058437T3 (da) | 2019-11-14 | 2020-11-13 | Matrix-metalloproteinase-(MMP)-inhibitorer og fremgangsmåder til anvendelse heraf |
Country Status (16)
| Country | Link |
|---|---|
| US (3) | US20230014855A1 (da) |
| EP (1) | EP4058437B9 (da) |
| JP (1) | JP7653986B2 (da) |
| KR (1) | KR20220100933A (da) |
| CN (1) | CN115667227B (da) |
| AU (1) | AU2020381485B2 (da) |
| BR (1) | BR112022009131A2 (da) |
| CA (1) | CA3158234A1 (da) |
| DK (1) | DK4058437T3 (da) |
| ES (1) | ES3009421T3 (da) |
| FI (1) | FI4058437T3 (da) |
| HU (1) | HUE069818T2 (da) |
| PL (1) | PL4058437T3 (da) |
| PT (1) | PT4058437T (da) |
| TW (1) | TW202132282A (da) |
| WO (1) | WO2021097190A1 (da) |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE0100902D0 (sv) * | 2001-03-15 | 2001-03-15 | Astrazeneca Ab | Compounds |
| GB0221246D0 (en) * | 2002-09-13 | 2002-10-23 | Astrazeneca Ab | Compounds |
| US7041693B2 (en) * | 2002-10-04 | 2006-05-09 | Bristol-Myers Squibb Company | Hydantoin derivatives as inhibitors of matrix metalloproteinases and/or TNF-α converting enzyme (TACE) |
| KR20070032787A (ko) * | 2004-07-16 | 2007-03-22 | 쉐링 코포레이션 | 염증 질환 치료용 히단토인 유도체 |
| JP5042833B2 (ja) * | 2004-08-19 | 2012-10-03 | クエスト ファーマシューティカル サーヴィシーズ | マクロファージエラスターゼの阻害剤としての５−［３−（４−ベンジルオキシフェニルチオ）−フラ−２−イル］−イミダゾリジン−２，４−ジオン及び類似体 |
| CN101528691B (zh) | 2006-08-22 | 2014-11-26 | 兰贝克赛实验室有限公司 | 基质金属蛋白酶抑制剂 |
| NZ751777A (en) | 2016-08-19 | 2020-08-28 | Foresee Pharmaceuticals Co Ltd | Pharmaceutical composition and methods of uses |
| CN119462623A (zh) * | 2018-05-15 | 2025-02-18 | 逸达生物科技美国公司 | 基质金属蛋白酶（mmp）抑制剂及其应用方法 |
-
2020
- 2020-11-13 DK DK20886710.1T patent/DK4058437T3/da active
- 2020-11-13 HU HUE20886710A patent/HUE069818T2/hu unknown
- 2020-11-13 US US17/755,983 patent/US20230014855A1/en active Pending
- 2020-11-13 EP EP20886710.1A patent/EP4058437B9/en active Active
- 2020-11-13 JP JP2022528560A patent/JP7653986B2/ja active Active
- 2020-11-13 FI FIEP20886710.1T patent/FI4058437T3/fi active
- 2020-11-13 PT PT208867101T patent/PT4058437T/pt unknown
- 2020-11-13 AU AU2020381485A patent/AU2020381485B2/en active Active
- 2020-11-13 CN CN202080092693.5A patent/CN115667227B/zh active Active
- 2020-11-13 PL PL20886710.1T patent/PL4058437T3/pl unknown
- 2020-11-13 US US17/097,314 patent/US11673884B2/en active Active
- 2020-11-13 CA CA3158234A patent/CA3158234A1/en active Pending
- 2020-11-13 ES ES20886710T patent/ES3009421T3/es active Active
- 2020-11-13 KR KR1020227019948A patent/KR20220100933A/ko active Pending
- 2020-11-13 BR BR112022009131A patent/BR112022009131A2/pt unknown
- 2020-11-13 WO PCT/US2020/060387 patent/WO2021097190A1/en not_active Ceased
- 2020-11-16 TW TW109139957A patent/TW202132282A/zh unknown
-
2023
- 2023-04-28 US US18/309,031 patent/US12503460B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US12503460B2 (en) | 2025-12-23 |
| US20230014855A1 (en) | 2023-01-19 |
| TW202132282A (zh) | 2021-09-01 |
| HUE069818T2 (hu) | 2025-04-28 |
| AU2020381485A8 (en) | 2022-07-14 |
| JP2023502093A (ja) | 2023-01-20 |
| CA3158234A1 (en) | 2021-05-20 |
| WO2021097190A1 (en) | 2021-05-20 |
| ES3009421T3 (en) | 2025-03-26 |
| PT4058437T (pt) | 2025-02-10 |
| AU2020381485A1 (en) | 2022-06-16 |
| CN115667227A (zh) | 2023-01-31 |
| EP4058437A4 (en) | 2023-11-22 |
| KR20220100933A (ko) | 2022-07-18 |
| EP4058437A1 (en) | 2022-09-21 |
| JP7653986B2 (ja) | 2025-03-31 |
| US11673884B2 (en) | 2023-06-13 |
| EP4058437B1 (en) | 2024-10-16 |
| FI4058437T3 (fi) | 2025-01-21 |
| BR112022009131A2 (pt) | 2022-07-26 |
| CN115667227B (zh) | 2024-11-01 |
| EP4058437B9 (en) | 2025-01-15 |
| US20230365543A1 (en) | 2023-11-16 |
| US20210171509A1 (en) | 2021-06-10 |
| PL4058437T3 (pl) | 2025-05-05 |
| AU2020381485B2 (en) | 2025-08-14 |
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