DK384385A - Bicycliske forbindelser - Google Patents

Bicycliske forbindelser Download PDF

Info

Publication number: DK384385A
Authority: DK; Denmark
Prior art keywords: bicyclic; relations; bicyclic relations
Prior art date: 1984-08-24

Application number

DK384385A

Other languages

English (en)

Other versions

DK384385D0 (da

Inventor

Cedric Herbert Hassall

Geoffrey Lawton

Sally Redshaw

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-08-24

Filing date

1985-08-23

Publication date

1986-02-25

1984-08-24 Priority claimed from GB848421493A external-priority patent/GB8421493D0/en

1985-08-23 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

1985-08-23 Publication of DK384385D0 publication Critical patent/DK384385D0/da

1986-02-25 Publication of DK384385A publication Critical patent/DK384385A/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/04—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having less than three double bonds between ring members or between ring members and non-ring members

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Peptides Or Proteins (AREA)

DK384385A 1984-08-24 1985-08-23 Bicycliske forbindelser DK384385A (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB848421493A GB8421493D0 (en)	1984-08-24	1984-08-24	Bicyclic compounds
GB858513541A GB8513541D0 (en)	1984-08-24	1985-05-29	Bicyclic compounds

Publications (2)

Publication Number	Publication Date
DK384385D0 DK384385D0 (da)	1985-08-23
DK384385A true DK384385A (da)	1986-02-25

Family

ID=26288155

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK384385A DK384385A (da)	1984-08-24	1985-08-23	Bicycliske forbindelser

Country Status (14)

Country	Link
US (4)	US4692438A (da)
EP (1)	EP0172552A3 (da)
AU (1)	AU583843B2 (da)
CS (1)	CS255893B2 (da)
DK (1)	DK384385A (da)
ES (3)	ES8700258A1 (da)
FI (1)	FI853174A7 (da)
HU (1)	HU193446B (da)
IL (1)	IL76133A (da)
MC (1)	MC1694A1 (da)
NO (1)	NO161914C (da)
NZ (1)	NZ213130A (da)
PH (1)	PH21749A (da)
PT (1)	PT81015B (da)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4692438A (en) *	1984-08-24	1987-09-08	Hoffmann-La Roche Inc.	Pyridazo-diazepines, diazocines, and -triazepines having anti-hypertensive activity
ZW11586A1 (en) *	1985-07-01	1987-12-30	Hoffmann La Roche	Bicyclic compounds
GB8629875D0 (en) *	1986-12-15	1987-01-28	Hoffmann La Roche	Pyridazodiazepine derivatives
US5430145A (en) *	1990-10-18	1995-07-04	Merrell Dow Pharmaceuticals Inc.	Mercaptoacetylamide derivatives useful as inhibitors of enkephalinase and ace
US5308841A (en) *	1990-12-21	1994-05-03	Merrell Dow Pharmaceuticals Inc.	Amino and nitro containing tricyclic compounds useful as inhibitors of ACE
EP0534363B1 (en) *	1991-09-27	1997-07-09	Merrell Pharmaceuticals Inc.	Novel 2-substituted indane-2-mercaptoacetylamide derivatives useful as inhibitors of enkephalinase and ace
US5455242A (en) *	1991-09-27	1995-10-03	Merrell Dow Pharmaceuticals Inc.	Carboxyalkyl tricyclic derivatives useful as inhibitors of enkephalinase and ace
US5457196A (en) *	1991-09-27	1995-10-10	Merrell Dow Pharmaceuticals Inc.	2-substituted indane-2-carboxyalkyl derivatives useful as inhibitors of enkephalinase and ACE
EP0625987B1 (en) *	1992-02-14	1998-04-01	Merrell Pharmaceuticals Inc.	Aminoacetylmercaptoacetylamide derivatives useful as inhibitors of enkephalinase and ace
AU669364B2 (en) *	1992-05-15	1996-06-06	Merrell Pharmaceuticals Inc.	Novel mercaptoacetylamido pyridazo(1,2)pyridazine, pyrazolo(1,2)pyridazine, pyridazo(1,2-a)(1,2)diazepine and pyrazolo(1,2-a)(1,2)diazepine derivatives useful as inhibitors of enkephalinase and ace
US5420271A (en) *	1992-08-24	1995-05-30	Merrell Dow Pharmaceuticals, Inc.	2-substituted indane-2-mercaptoacetylamide tricyclic derivatives useful as inhibitors of enkephalinase
NZ256589A (en) *	1992-10-30	1996-05-28	Merrell Dow Pharma	Condensed azepine analogues and medicaments (where a is c, o or s and b is o or s)
WO1994022440A1 (en) *	1993-03-29	1994-10-13	Smithkline Beecham Corporation	Bicyclic compounds which inhibit platelet aggregation
ATE209205T1 (de) *	1994-02-14	2001-12-15	Merrell Pharma Inc	Indan-2-mercaptoacetylamid disulfidderivate als enkephalinase inhibitoren
US5530013A (en) *	1994-02-14	1996-06-25	American Home Products Corporation	Venlafaxine in the inducement of cognition enhancement
FI963169A7 (fi) *	1994-02-14	1996-08-13	Merrell Pharma Inc	Enkefalinaasin ja ACE:n inhibittoreina käyttökelpoisia uusia merkaptoa setyyliamido-1,3,4,5-tetrahydrobents/c/-atsepin-3-onidisulfidijohdanna isia
CA2183320C (en) *	1994-02-14	1999-10-26	Gary A. Flynn	Novel mercaptoacetylamide disulfide derivatives useful as inhibitors of enkephalinase and ace
CN1142831A (zh) *	1994-02-14	1997-02-12	默里尔药物公司	用作脑啡肽酶和ace抑制剂的新的2-取代的1，2-二氢化茚-2-巯基乙酰胺二硫化物衍生物
US5484783A (en) *	1994-03-24	1996-01-16	Merrell Dow Pharmaceuticals Inc.	Hypocholesterolemic, antiatherosclerotic and hypotriglyceridemic mercaptoacetylamide and benzazapine derivatives
NZ282565A (en) *	1994-03-24	1999-11-29	Merrell Pharma Inc	Condensed mercaptoacetylamidedisulphidebenzazepines used in treating elevated cholesterol levels, atherosclerosis, and hypotriglyceridemia
CA2184696C (en) *	1994-03-24	2001-01-02	Gary A. Flynn	Hypocholesterolemic, antiatherosclerotic and hypotriglyceridemic aminoacetylmercapto derivatives
US6703500B2 (en)	1998-08-19	2004-03-09	Vertex Pharmaceuticals, Incorporated	Method of preparing bicyclic intermediates from piperazic acid or an ester thereof useful in the manufacture of caspase inhibitors
US6559304B1 (en) *	1998-08-19	2003-05-06	Vertex Pharmaceuticals Incorporated	Method for synthesizing caspase inhibitors
US6177565B1 (en) *	1998-08-19	2001-01-23	Vertex Pharmaceuticals Inc.	Process for synthesizing piperazic acid
NZ520998A (en)	2000-05-04	2004-11-26	Vertex Pharma	Asymmetric synthesis of piperazic acid and derivatives thereof
GB0119305D0 (en)	2001-04-12	2001-10-03	Aventis Pharma Gmbh	Mercaptoacetylamide derivatives,a process for their preparation and their use
WO2010010427A1 (en) *	2008-07-25	2010-01-28	Chuluun Enkhbold	A method of solid fuel beneficiation and transportation to thermoelectric power stations
EP2513116B1 (en)	2009-12-16	2015-08-19	Hetero Research Foundation	Polymorphs of darunavir
ES2595235T3 (es)	2010-05-20	2016-12-28	Hetero Research Foundation	Sal clorhidrato cristalina de darunavir

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4308094A (en) *	1977-02-02	1981-12-29	Sanyo Electric Co., Ltd.	Diaphragm for speaker and method of producing same
IL60617A0 (en) *	1979-07-23	1980-09-16	Sparamedica Ag	Triazolopyridazine derivative,their preparation and pharmaceutical compositions containing them
DE3062972D1 (en) *	1979-09-19	1983-06-09	Hoffmann La Roche	Pyridazopyridazine derivatives, processes for their preparation and pharmaceutical compositions containing these pyridazopyridazine derivatives
EP0042100A1 (de) *	1980-06-13	1981-12-23	F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft	Pyrazolopyridazin-Derivate, Zwischenprodukte und Verfahren zu deren Herstellung, sowie diese enthaltende Arzneimittel
GB2128984B (en) *	1982-05-12	1985-05-22	Hoffmann La Roche	Diaza-bicyclic compounds
US4692438A (en) *	1984-08-24	1987-09-08	Hoffmann-La Roche Inc.	Pyridazo-diazepines, diazocines, and -triazepines having anti-hypertensive activity

1985
- 1985-08-12 US US06/764,372 patent/US4692438A/en not_active Expired - Fee Related
- 1985-08-15 CS CS855928A patent/CS255893B2/cs unknown
- 1985-08-16 NZ NZ213130A patent/NZ213130A/en unknown
- 1985-08-19 AU AU46415/85A patent/AU583843B2/en not_active Ceased
- 1985-08-19 FI FI853174A patent/FI853174A7/fi not_active Application Discontinuation
- 1985-08-19 IL IL76133A patent/IL76133A/xx unknown
- 1985-08-19 EP EP85110370A patent/EP0172552A3/de not_active Withdrawn
- 1985-08-21 HU HU853187A patent/HU193446B/hu not_active IP Right Cessation
- 1985-08-21 MC MC851791A patent/MC1694A1/fr unknown
- 1985-08-21 PH PH32671A patent/PH21749A/en unknown
- 1985-08-23 NO NO853336A patent/NO161914C/no unknown
- 1985-08-23 DK DK384385A patent/DK384385A/da not_active Application Discontinuation
- 1985-08-23 PT PT81015A patent/PT81015B/pt unknown
- 1985-08-23 ES ES546360A patent/ES8700258A1/es not_active Expired
1986
- 1986-02-17 ES ES552397A patent/ES8705443A1/es not_active Expired
- 1986-02-17 ES ES552398A patent/ES8705444A1/es not_active Expired
1987
- 1987-05-11 US US07/048,172 patent/US4785093A/en not_active Expired - Fee Related
- 1987-06-15 US US07/062,033 patent/US4762924A/en not_active Expired - Fee Related
1988
- 1988-07-12 US US07/217,805 patent/US4826980A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
ES8705444A1 (es)	1987-05-01
US4785093A (en)	1988-11-15
NO161914B (no)	1989-07-03
IL76133A (en)	1989-12-15
NO853336L (no)	1986-02-25
HU193446B (en)	1987-10-28
NZ213130A (en)	1988-05-30
HUT38644A (en)	1986-06-30
AU4641585A (en)	1986-02-27
ES552397A0 (es)	1987-05-01
US4692438A (en)	1987-09-08
MC1694A1 (fr)	1986-07-18
PH21749A (en)	1988-02-18
US4762924A (en)	1988-08-09
CS255893B2 (en)	1988-03-15
EP0172552A2 (de)	1986-02-26
US4826980A (en)	1989-05-02
ES8705443A1 (es)	1987-05-01
FI853174L (fi)	1986-02-25
CS592885A2 (en)	1987-07-16
EP0172552A3 (de)	1989-01-11
PT81015B (en)	1987-08-24
PT81015A (en)	1985-09-01
ES552398A0 (es)	1987-05-01
ES546360A0 (es)	1986-10-01
ES8700258A1 (es)	1986-10-01
FI853174A7 (fi)	1986-02-25
AU583843B2 (en)	1989-05-11
FI853174A0 (fi)	1985-08-19
DK384385D0 (da)	1985-08-23
NO161914C (no)	1989-10-11
IL76133A0 (en)	1985-12-31

Publication	Publication Date	Title
DK384385D0 (da)	1985-08-23	Bicycliske forbindelser
DK499485D0 (da)	1985-10-30	Forbindelser
DK424685A (da)	1986-03-21	Forbindelser
AT380762B (de)	1986-07-10	Hoergeraet
AT379929B (de)	1986-03-10	Hoergeraet
ATA98284A (de)	1991-06-15	Schalplatte
SE455355B (sv)	1988-07-04	Tryckstromstellare
AT386724B (de)	1988-10-10	Haecksler
ATA135485A (de)	1990-07-15	Maishaecksler
DK284486A (da)	1986-12-20	Bicycliske forbindelser
ATA237384A (de)	1989-03-15	Maehwerk
DK297386D0 (da)	1986-06-24	Bicycliske forbindelser
ATE36715T1 (de)	1988-09-15	7-d-mandelamido-3-(1-sulfomethyltetrazol-5us840229
ATA45484A (de)	1985-05-15	Kimme
AT389296B (de)	1989-11-10	Elektrokoagulator
BR8402733A (pt)	1986-01-07	Divisoria
NO862632D0 (no)	1986-06-30	Bicykliske forbindelser.
DK521885D0 (da)	1985-11-12	Saerlig fremgangsmaade
ES280124Y (es)	1985-06-16	Conjunto de tapon-precinto
AR231237A1 (es)	1984-10-31	Calzado-patin
BR6401828U (pt)	1986-06-10	Panquequeira
BR8400079A (pt)	1984-06-12	Trefina
BR6400357U (pt)	1985-07-09	Moto-bomba
BR6400397U (pt)	1985-10-29	Isqueiro-cinzeiro
BR6400601U (pt)	1985-11-26	Fotocheque

Legal Events

Date	Code	Title	Description
1991-04-22	AHB	Application shelved due to non-payment