[go: up one dir, main page]

DK361483D0 - Gaerhybridvektorer samt deres anvendelse ved fremstilling af polypeptider - Google Patents

Gaerhybridvektorer samt deres anvendelse ved fremstilling af polypeptider

Info

Publication number
DK361483D0
DK361483D0 DK3614/83A DK361483A DK361483D0 DK 361483 D0 DK361483 D0 DK 361483D0 DK 3614/83 A DK3614/83 A DK 3614/83A DK 361483 A DK361483 A DK 361483A DK 361483 D0 DK361483 D0 DK 361483D0
Authority
DK
Denmark
Prior art keywords
hybrid vectors
yeast
promoter
preparing polypeptides
year hybrid
Prior art date
Application number
DK3614/83A
Other languages
English (en)
Other versions
DK361483A (da
DK174905B1 (da
Inventor
Albert Hinnen
Bernd Meyhack
Francois Meyer
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB838315145A external-priority patent/GB8315145D0/en
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of DK361483D0 publication Critical patent/DK361483D0/da
Publication of DK361483A publication Critical patent/DK361483A/da
Application granted granted Critical
Publication of DK174905B1 publication Critical patent/DK174905B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/56—IFN-alpha
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/036—Fusion polypeptide containing a localisation/targetting motif targeting to the medium outside of the cell, e.g. type III secretion
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Biomedical Technology (AREA)
  • Communicable Diseases (AREA)
  • Toxicology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Physics & Mathematics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Alcoholic Beverages (AREA)
DK198303614A 1982-08-09 1983-08-08 DNA-sekvens og fremgangsmåde til den fremstilling, gærhybridvektorer og Saccharomyces cerevisiae indeholdende sekvensen henholdsvis vektoren og fremgangsmåder til deres fremstilling samt deres anvendelse ved fremstilling af polypeptider DK174905B1 (da)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB8222883 1982-08-09
GB8222883 1982-08-09
GB8237026 1982-12-31
GB8237026 1982-12-31
GB838315145A GB8315145D0 (en) 1982-08-09 1983-06-02 Yeast hybrid vectors
GB8315145 1983-06-02

Publications (3)

Publication Number Publication Date
DK361483D0 true DK361483D0 (da) 1983-08-08
DK361483A DK361483A (da) 1984-02-10
DK174905B1 DK174905B1 (da) 2004-02-16

Family

ID=27261693

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198303614A DK174905B1 (da) 1982-08-09 1983-08-08 DNA-sekvens og fremgangsmåde til den fremstilling, gærhybridvektorer og Saccharomyces cerevisiae indeholdende sekvensen henholdsvis vektoren og fremgangsmåder til deres fremstilling samt deres anvendelse ved fremstilling af polypeptider

Country Status (20)

Country Link
EP (1) EP0100561B1 (da)
JP (2) JPH0653073B2 (da)
AT (1) ATE43636T1 (da)
AU (1) AU566348B2 (da)
CA (1) CA1341381C (da)
CY (1) CY1451A (da)
DD (1) DD218118A5 (da)
DE (1) DE3379960D1 (da)
DK (1) DK174905B1 (da)
ES (3) ES8505724A1 (da)
FI (1) FI80720C (da)
GB (1) GB2125047B (da)
GR (1) GR78924B (da)
HK (1) HK90688A (da)
HU (1) HU204095B (da)
IE (1) IE55598B1 (da)
NO (1) NO172548C (da)
NZ (1) NZ205178A (da)
PH (1) PH25617A (da)
PT (1) PT77167B (da)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2125047B (en) * 1982-08-09 1986-02-19 Ciba Geigy Ag Yeast hybrid vectors and their use for the production of polypeptides
DE3381619D1 (de) * 1982-08-16 1990-07-05 Chemo Sero Therapeut Res Inst Pendelvektor.
JPS5936699A (ja) * 1982-08-20 1984-02-28 Chemo Sero Therapeut Res Inst シヤトルベクタ−
JPS5931799A (ja) * 1982-08-16 1984-02-20 Science & Tech Agency Ｂ型肝炎ウイルス遺伝子を組込んだ組換えプラスミド
AU584580B2 (en) * 1982-09-08 1989-06-01 Smith Kline - Rit Hepatitis B virus vaccine
JPS5974988A (ja) * 1982-10-20 1984-04-27 Suntory Ltd 酵母の誘導発現型プラスミドベクタ−およびその利用方法
ZA843275B (en) * 1983-05-05 1984-12-24 Hoffmann La Roche Novel vectors for interferon expression
FI86746C (fi) * 1983-11-21 1992-10-12 Ciba Geigy Ag Foerfarande foer framstaellning av maensklig vaevnads-plasminogenaktivator (tpa) med hjaelp av saccharomyces cerevisiae -jaest och i foerfarandet anvaenda hybridvektorer
JPS60248181A (ja) * 1984-05-23 1985-12-07 Shiseido Co Ltd 酵母発現ベクタ−
AU600885B2 (en) * 1984-05-25 1990-08-30 Zymogenetics Inc. Stable DNA constructs
US5723292A (en) * 1984-05-25 1998-03-03 Zymogenetics, Inc. Stable DNA constructs
GB8415186D0 (en) * 1984-06-14 1984-07-18 Ciba Geigy Ag Polypeptides
JPS61502795A (ja) * 1984-07-09 1986-12-04 レモント，ジェフリ−・エフ 酵母クロ−ニング　ビ−クル
JPS61502655A (ja) * 1984-07-09 1986-11-20 インテグレ−テッド・ジェネティックス・インコ−ポレ−テッド 酵母クロ−ニングビヒクル
JPS61503002A (ja) * 1984-07-31 1986-12-25 アプライド・リサーチ・システムズ・エイアールエス・ホールディング・ナムローゼ・フェンノートシャップ 酵母クロ−ニングベクタ−
JPS61103895A (ja) * 1984-10-26 1986-05-22 Green Cross Corp:The ＨＢｓＡｇの精製方法
US5336609A (en) * 1984-12-06 1994-08-09 Labofina, S.A. Transformed yeasts for producing lysozyme, plasmids used for this transformation, method of producing lysozyme
EP0194006B1 (en) * 1985-02-01 1992-04-29 Imperial Chemical Industries Plc Analogous interferon polypeptides, process for their preparation and pharmaceutical compositions containing them
GB8521496D0 (en) * 1985-08-29 1985-10-02 Ciba Geigy Ag Repressible yeast promoters
JPS62151183A (ja) * 1985-09-18 1987-07-06 Green Cross Corp:The 酵母プロモ−タ−及び異種蛋白質の製造方法
EP0216573B1 (en) * 1985-09-18 1990-11-22 Green Cross Corporation Yeast promoter and method of producing heterologous proteins
GB8530631D0 (en) 1985-12-12 1986-01-22 Ciba Geigy Ag Thrombin inhibitors
GB2188049B (en) * 1986-03-15 1990-09-05 Ciba Geigy Ag Insecticidal proteinaceous substance
EP0240224A3 (en) * 1986-03-31 1989-02-01 Interferon Sciences, Inc. An alpha interferon analogue
US4857467A (en) * 1986-07-23 1989-08-15 Phillips Petroleum Company Carbon and energy source markers for transformation of strains of the genes Pichia
DE3789413T2 (de) 1986-10-03 1994-07-28 Ciba Geigy Ag Lymphokin-ähnliche Peptide.
US5013652A (en) * 1986-10-14 1991-05-07 Genex Corporation Composite yeast vectors
US5180667A (en) * 1988-03-07 1993-01-19 Ciba-Geigy Corporation Genes encoding eglin C mutants
DE58907373D1 (de) * 1988-03-07 1994-05-11 Ciba Geigy Modifizierte Proteine.
DE68928124T2 (de) 1988-09-02 1997-10-16 Chiron Corp., Emeryville, Calif. Makrophagenabgeleiteter entzündungsmediator(mip-2)
JPH02145193A (ja) * 1988-11-19 1990-06-04 Lotte Confectionery Co Ltd 遺伝子の組換えによる酵母でのヒト・アルファ・インターフェロンの製造方法
AU648214B2 (en) * 1991-12-31 1994-04-14 Lucky Limited Recombinant gene coding for human alpha interferon and expression vector thereof, etc.
DE69434492T2 (de) 1993-03-10 2006-07-13 Smithkline Beecham Corp. Phosphodiesterase des menschlichen gehirns
US6500645B1 (en) 1994-06-17 2002-12-31 Novo Nordisk A/S N-terminally extended proteins expressed in yeast
DE60335497D1 (de) 2002-09-13 2011-02-03 Cornell Res Foundation Inc Ergillus-phytasen
DE102005030552B4 (de) * 2005-06-22 2009-05-28 Eucodis Bioscience Selektion von Phosphatase-Aktivität
CN102059495A (zh) * 2010-11-06 2011-05-18 中国长江航运集团宜昌船厂 一种船体框架胎模及加工方法
CN105821078A (zh) 2010-12-09 2016-08-03 巴斯德研究所 用于获得高产量重组蛋白表达的基于mgmt的方法
WO2013059507A1 (en) 2011-10-20 2013-04-25 University Of Iowa Research Foundation N-demethyase genes and uses thereof
BR112014013745B1 (pt) 2011-12-09 2022-06-14 Institut Pasteur Método de teste in vitro, kit de detecção e seu uso, método in vitro de diagnóstico, método de fabricação de kit, e teste de imunosseleção multiplex
US20150184166A1 (en) 2012-06-15 2015-07-02 Uinversity of Iowa Research Foundation Caffeine responsive promoters and regulatory genes
WO2022049409A1 (en) 2020-09-02 2022-03-10 Sia Terragen Express diagnosticum for sars-cov-2

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2458585A1 (fr) * 1979-06-07 1981-01-02 Pasteur Institut Procede de production de proteines par expression des genes correspondants dans des micro-organismes et vecteurs susceptibles d'etre mis en oeuvre dans de tels procedes
AU546577B2 (en) * 1980-02-25 1985-09-05 Trustees Of Columbia University, The Use of eucaryotic promoter sequences in the production of proteinaceous materials
IL63270A0 (en) * 1980-08-05 1981-10-30 Univ Leland Stanford Junior Eukaryotic autonomously replicating segment
IL63035A (en) * 1980-09-09 1985-05-31 Univ California Dnas capable of replication and stable mitotic maintenance in a host eukaryote,their preparation and eukaryotic cells comprising them
NZ199722A (en) * 1981-02-25 1985-12-13 Genentech Inc Dna transfer vector for expression of exogenous polypeptide in yeast;transformed yeast strain
US4615974A (en) * 1981-08-25 1986-10-07 Celltech Limited Yeast expression vectors
NZ201705A (en) * 1981-08-31 1986-03-14 Genentech Inc Recombinant dna method for production of hepatitis b surface antigen in yeast
GB2125047B (en) * 1982-08-09 1986-02-19 Ciba Geigy Ag Yeast hybrid vectors and their use for the production of polypeptides
JPS5931799A (ja) * 1982-08-16 1984-02-20 Science & Tech Agency Ｂ型肝炎ウイルス遺伝子を組込んだ組換えプラスミド

Also Published As

Publication number Publication date
GR78924B (da) 1984-10-02
EP0100561B1 (en) 1989-05-31
JPH0515379A (ja) 1993-01-26
NO172548B (no) 1993-04-26
FI80720B (fi) 1990-03-30
ES524816A0 (es) 1985-06-01
PT77167B (en) 1986-03-20
ES8505724A1 (es) 1985-06-01
DE3379960D1 (en) 1989-07-06
FI80720C (fi) 1990-07-10
GB2125047A (en) 1984-02-29
EP0100561A1 (en) 1984-02-15
AU1768283A (en) 1984-02-16
JPH0653073B2 (ja) 1994-07-20
NO832848L (no) 1984-02-10
PH25617A (en) 1991-08-08
DK361483A (da) 1984-02-10
GB8319099D0 (en) 1983-08-17
JPH0813277B2 (ja) 1996-02-14
ATE43636T1 (de) 1989-06-15
PT77167A (en) 1983-09-01
IE55598B1 (en) 1990-11-21
ES8607026A1 (es) 1986-05-16
ES540881A0 (es) 1986-05-16
ES8607391A1 (es) 1986-05-16
FI832825A0 (fi) 1983-08-05
HU204095B (en) 1991-11-28
NZ205178A (en) 1986-09-10
JPS5948082A (ja) 1984-03-19
AU566348B2 (en) 1987-10-15
HK90688A (en) 1988-11-18
CA1341381C (en) 2002-08-06
NO172548C (no) 1993-08-04
GB2125047B (en) 1986-02-19
DD218118A5 (de) 1985-01-30
CY1451A (en) 1989-03-10
DK174905B1 (da) 2004-02-16
FI832825L (fi) 1984-02-10
IE831860L (en) 1984-02-09
ES540880A0 (es) 1986-05-16

Similar Documents

Publication Publication Date Title
DK361483A (da) Gaerhybridvektorer samt deres anvendelse ved fremstilling af polypeptider
BR8206068A (pt) Composicoes de materia,polipeptideo,sequencia de dna,veiculo de expressao replicavel,microorganismo ou cultura celular,plasmideo,extrato de cultura celular,cultura de celulas transformantes,uso de interferon imune humano maduro,processo de expressao de um gene,processo para producao de um polipeptideo,processo para producao de um veiculo de expressao,e produto obtido por tais processos
EG19101A (en) Process for preparing of expression of human proapolipoprotein A.1.
BR8200191A (pt) Celula viva renina preprorrenina prorrenina processo para obter expressao de preporrenina prorrenina e renina gene de prorrenina preprorrenina e renina e coli material dna recombinador saccharomyces cerevisiae polipetidio processo para exprimir um gene
YU44186B (en) Process for obtaining recombinant dnk molecules
ATE192500T1 (de) Rekombinante viren vektoren zur expression in muskelzellen
EP0483115A3 (en) Regulatory region for heterologous gene expression in yeast
DK163937B (da) Strukturelt gen, som koder for autentisk humant serumalbumin til ekspression i en ikke-human vaert, fremgangsmaade til fremstilling deraf, rekombinant-dna-molekyle indeholdende genet, vaertsorganisme transformeret dermed og fremgangsmaade til fremstilling af autentisk humant serumalbumin
DE69028499D1 (de) Neues Verfahren zur Produktion von nichtfusioniertem Protein in E. coli
EP0395706A4 (en) Production of gonorrheal pi proteins and vaccines
ATE82985T1 (de) Strukturelles phosphoprotein (pp 150) des menschlichen cytomegalovirus, seine herstellung und verwendung.
EP0222279A3 (en) Production of active proteins containing cystine residues
AU7949991A (en) Cloned n-methylhydantoinase
EP0072541A3 (en) Human leukocyte interferons, process for their microbial production, intermediates therefor and compositions containing them
GR3020035T3 (en) Mammalian cell derived autonomously replicating sequence DNA fragments having affinity to DNA binding proteins
ATE87977T1 (de) Herstellung menschlichen somatomedins c.
AU1321988A (en) The cloning of malaria-specific dna sequences: isolation of the gene for the 140 kd protein
DE3853590D1 (de) Rinder granulocyt-makrophagenkolonie stimulierender faktor.
EP0323838A3 (de) Expressionsvektor und Verfahren zur regulierbaren Herstellung von Proteinen in Eukaryonten

Legal Events

Date Code Title Description
PUP Patent expired