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DK366889A - Peptidderivat - Google Patents

Peptidderivat Download PDF

Info

Publication number
DK366889A
DK366889A DK366889A DK366889A DK366889A DK 366889 A DK366889 A DK 366889A DK 366889 A DK366889 A DK 366889A DK 366889 A DK366889 A DK 366889A DK 366889 A DK366889 A DK 366889A
Authority
DK
Denmark
Prior art keywords
peptide
ferm
chem
substance
production
Prior art date
Application number
DK366889A
Other languages
Danish (da)
English (en)
Other versions
DK366889D0 (da
Inventor
Masakuni Okuhara
Toshio Goto
Yasuhiro Hori
Takashi Fujita
Hirotsugu Ueda
Nobuharu Shigematsu
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10641100&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK366889(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Publication of DK366889D0 publication Critical patent/DK366889D0/da
Publication of DK366889A publication Critical patent/DK366889A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/101—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Reinforced Plastic Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
DK366889A 1988-07-26 1989-07-25 Peptidderivat DK366889A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888817743A GB8817743D0 (en) 1988-07-26 1988-07-26 Fr901228 substance & preparation thereof

Publications (2)

Publication Number Publication Date
DK366889D0 DK366889D0 (da) 1989-07-25
DK366889A true DK366889A (da) 1990-01-27

Family

ID=10641100

Family Applications (1)

Application Number Title Priority Date Filing Date
DK366889A DK366889A (da) 1988-07-26 1989-07-25 Peptidderivat

Country Status (16)

Country Link
US (1) US4977138A (zh)
EP (1) EP0352646B1 (zh)
JP (1) JPH0764872B2 (zh)
CN (1) CN1040054A (zh)
AT (1) ATE94561T1 (zh)
AU (1) AU3829089A (zh)
CA (1) CA1335083C (zh)
DE (1) DE68909139T2 (zh)
DK (1) DK366889A (zh)
ES (1) ES2058411T3 (zh)
FI (1) FI893359L (zh)
GB (1) GB8817743D0 (zh)
HU (1) HU211514A9 (zh)
IL (1) IL90949A0 (zh)
NO (1) NO893021L (zh)
ZA (1) ZA895121B (zh)

Families Citing this family (55)

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US5130414A (en) * 1989-11-30 1992-07-14 Arizona Board Of Regents, A Body Corporate Of Arizona State University Isolation and structural elucidation of the cyclic peptide hymenistatin 1
JPH06247964A (ja) * 1993-02-22 1994-09-06 Snow Brand Milk Prod Co Ltd 新規生理活性物質ｈｓ−１及びその製造方法
HUP9904074A3 (en) * 1996-11-22 2001-10-29 Pioneer Hi Bred Int Moniliformin detoxification compositions and methods
CN1173990C (zh) 1999-01-13 2004-11-03 山之内制药株式会社 缩肽化合物
ATE353663T1 (de) * 1999-12-08 2007-03-15 Cyclacel Pharmaceuticals Inc Verwendung von depsipeptide und deren analoge als immunosuppressiva zur behandlung von infektionskrankheiten, autoimmunerkrankungen, allergien und hyperproliferativer hautkrankheiten
US6828302B1 (en) 1999-12-08 2004-12-07 Xcyte Therapies, Inc. Therapeutic uses of depsipeptides and congeners thereof
EP1302476B1 (en) * 2000-07-17 2009-03-11 Astellas Pharma Inc. Reduced fk228 and use thereof
WO2002020817A1 (en) * 2000-09-01 2002-03-14 Fujisawa Pharmaceutical Co., Ltd. A method of producing fr901228
WO2003015810A1 (en) * 2001-08-21 2003-02-27 Fujisawa Pharmaceutical Co., Ltd. Medicinal use of histone deacetylase inhibitor and method of evaluating antitumor effect thereof
US20040132643A1 (en) * 2002-01-09 2004-07-08 Fojo Antonio Tito Histone deacelylase inhibitors in diagnosis and treatment of thyroid neoplasms
CN1649645A (zh) * 2002-04-05 2005-08-03 藤泽药品工业株式会社 用于治疗肾癌的缩酚肽
US20080233562A1 (en) * 2003-02-19 2008-09-25 Astellas Pharma Inc. Method of Estimating Antitumor Effect of Histone Deacetylase Inhibitor
SI2238982T1 (sl) * 2003-06-27 2013-01-31 Astellas Pharma Inc. Terapevtsko sredstvo za mehkotkivni sarkom
ATE471740T1 (de) 2003-09-25 2010-07-15 Astellas Pharma Inc Antitumorales mittel mit einem histon-deacetylase-hemmer und einem topoisomerase-ii-hemmer
WO2005058298A2 (en) * 2003-12-10 2005-06-30 Wisconsin Alumni Research Foundation Fk228 analogs and their use as hdac-inhibitors
US20050187148A1 (en) * 2004-02-25 2005-08-25 Yoshinori Naoe Antitumor agent
US7951780B2 (en) * 2004-02-25 2011-05-31 Astellas Pharma Inc. Antitumor agent
WO2005115149A2 (en) * 2004-05-20 2005-12-08 Dow Agrosciences Llc Insectidal activity of a cyclic peptide
US20060106049A1 (en) * 2004-11-17 2006-05-18 The University Of Chicago Histone deacetylase inhibitors and methods of use
GB0511266D0 (en) * 2005-06-02 2005-07-13 Trust Chemical compounds
JP2009519224A (ja) * 2005-11-18 2009-05-14 グロスター ファーマシューティカルズ， インコーポレイテッド Ｈｄａｃインヒビターｆｋ２２８の代謝産物誘導体
EP2012801A4 (en) * 2006-04-24 2009-08-05 Gloucester Pharmaceuticals Inc GEMCITABINE COMBINATION THERAPY
US8957027B2 (en) 2006-06-08 2015-02-17 Celgene Corporation Deacetylase inhibitor therapy
US8691534B2 (en) * 2006-12-29 2014-04-08 Celgene Corporation Preparation of romidepsin
US20100093610A1 (en) 2006-12-29 2010-04-15 Vrolijk Nicholas H Romidepsin-based treatments for cancer
US8148102B2 (en) * 2007-02-08 2012-04-03 Uwm Research Foundation, Inc. Sequences for FK228 biosynthesis and methods of synthesizing FK228 and FK228 analogs
US20110060021A1 (en) * 2009-08-19 2011-03-10 Yiqiang Cheng Histone deacetylase inhibitors and uses thereof
AR080234A1 (es) * 2010-02-25 2012-03-21 Marrone Bio Innovations Inc Cepa bacteriana aislada del genero burkholderia y metabolitos pesticidas del mismo
AU2011279303B2 (en) 2010-07-12 2015-07-16 Celgene Corporation Romidepsin solid forms and uses thereof
US8859502B2 (en) 2010-09-13 2014-10-14 Celgene Corporation Therapy for MLL-rearranged leukemia
AU2012301466B2 (en) * 2011-08-27 2015-07-23 Marrone Bio Innovations, Inc. Isolated bacterial strain of the genus Burkholderia and pesticidal metabolites therefrom-formulations and uses
CN104114182A (zh) 2011-09-23 2014-10-22 细胞基因公司 罗米地辛和5-阿扎胞苷在治疗淋巴瘤中的应用
WO2013049093A1 (en) 2011-09-26 2013-04-04 Celgene Corporation Combination therapy for chemoresistant cancers
US9963482B2 (en) 2011-09-30 2018-05-08 Tohoku University Phosphatidylinositol-3-kinase inhibitor and pharmaceutical composition
WO2013085902A1 (en) 2011-12-05 2013-06-13 The University Of Texas M.D. Combination therapy methods for treating an inflammatory breast cancer
US20130184225A1 (en) * 2012-01-12 2013-07-18 Lianfeng Huang Romidepsin formulations and uses thereof
AU2013202506B2 (en) 2012-09-07 2015-06-18 Celgene Corporation Resistance biomarkers for hdac inhibitors
AU2013202507B9 (en) 2012-11-14 2015-08-13 Celgene Corporation Inhibition of drug resistant cancer cells
CN103877010B (zh) * 2012-12-21 2018-06-01 正大天晴药业集团股份有限公司 一种罗米地辛溶液的制备方法
US9006462B2 (en) 2013-02-28 2015-04-14 Dermira, Inc. Glycopyrrolate salts
US8558008B2 (en) 2013-02-28 2013-10-15 Dermira, Inc. Crystalline glycopyrrolate tosylate
KR102377252B1 (ko) 2013-02-28 2022-03-22 저니 메디컬 코퍼레이션 글리코피롤레이트 염
CN103173390B (zh) * 2013-03-16 2014-09-10 浙江海正药业股份有限公司 一种紫色杆菌菌株及其应用
CN104072589B (zh) * 2013-03-29 2017-09-22 浙江海正药业股份有限公司 抗肿瘤三硫化合物及其制备方法与应用
CN104450837B (zh) * 2013-09-18 2019-01-01 上海医药工业研究院 一种用于生产罗米地辛的方法及发酵培养基
CN104447950A (zh) * 2013-09-18 2015-03-25 上海医药工业研究院 一种罗米地辛的分离纯化方法
NZ630311A (en) 2013-12-27 2016-03-31 Celgene Corp Romidepsin formulations and uses thereof
US10294276B2 (en) * 2014-03-04 2019-05-21 Concord Biotech Limited Process for isolation of romidepsin from fermentation broth and preparation of crystals of romidepsin
CN104894195B (zh) * 2014-03-07 2018-11-13 上海医药工业研究院 一种提高fk228产量的发酵培养基
CN104262456B (zh) * 2014-09-11 2018-01-09 浙江海正药业股份有限公司 一种罗米地辛的新晶型及其制备方法和用途
JP6980534B2 (ja) 2015-06-25 2021-12-15 ザ チルドレンズ メディカル センター コーポレーション 造血幹細胞の増大、富化、および維持に関する方法および組成物
WO2017068596A1 (en) * 2015-10-20 2017-04-27 Msn Laboratories Private Limited An improved process for the preparation of (1s, 4s, 7z, 10s, 16e, 21r)- 7-ethylidene-4,21-bis(1-methylethyl)-2-oxa-12,13-dithia-5, 8, 20, 23- tetraazabicyclo[8.7.6]tricos-16-ene-3, 6, 9, 19, 22-pentone
EP4049665B1 (en) 2016-03-15 2025-03-12 The Children's Medical Center Corporation Methods and compositions relating to hematopoietic stem cell expansion
WO2020123242A1 (en) 2018-12-14 2020-06-18 Pioneer Hi-Bred International, Inc. Biologicals and their use in plants
EP3902908A4 (en) * 2018-12-24 2024-01-03 Pro Farm Group, Inc. A method for increasing romidepsin production from fermentation broth

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986006065A1 (en) * 1985-04-18 1986-10-23 Pfizer Inc. Transformation product of thiosporamicin
EP0253245B1 (en) * 1986-07-08 1992-10-14 Takeda Chemical Industries, Ltd. Biologically active peptides tan-866
US4777160A (en) * 1986-09-18 1988-10-11 Bristol-Myers BU-2867T peptide antibiotics

Also Published As

Publication number Publication date
NO893021L (no) 1990-01-29
IL90949A0 (en) 1990-02-09
JPH0764872B2 (ja) 1995-07-12
DK366889D0 (da) 1989-07-25
ZA895121B (en) 1990-08-29
FI893359A0 (fi) 1989-07-11
ES2058411T3 (es) 1994-11-01
EP0352646B1 (en) 1993-09-15
ATE94561T1 (de) 1993-10-15
HU211514A9 (en) 1995-11-28
NO893021D0 (no) 1989-07-25
US4977138A (en) 1990-12-11
DE68909139T2 (de) 1994-02-10
AU3829089A (en) 1990-02-01
GB8817743D0 (en) 1988-09-01
CN1040054A (zh) 1990-02-28
FI893359A7 (fi) 1990-01-27
DE68909139D1 (de) 1993-10-21
EP0352646A3 (en) 1990-10-31
EP0352646A2 (en) 1990-01-31
FI893359L (fi) 1990-01-27
JPH0285296A (ja) 1990-03-26
CA1335083C (en) 1995-04-04

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