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DK3115370T3 - Biologisk aktive peptider - Google Patents

Biologisk aktive peptider Download PDF

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Publication number
DK3115370T3
DK3115370T3 DK16172509.8T DK16172509T DK3115370T3 DK 3115370 T3 DK3115370 T3 DK 3115370T3 DK 16172509 T DK16172509 T DK 16172509T DK 3115370 T3 DK3115370 T3 DK 3115370T3
Authority
DK
Denmark
Prior art keywords
biologically active
active peptides
peptides
biologically
active
Prior art date
Application number
DK16172509.8T
Other languages
English (en)
Inventor
Friedrich Scheiflinger
Michael Dockal
Original Assignee
Baxalta GmbH
Baxalta Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxalta GmbH, Baxalta Inc filed Critical Baxalta GmbH
Application granted granted Critical
Publication of DK3115370T3 publication Critical patent/DK3115370T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745Blood coagulation or fibrinolysis factors
    • C07K14/755Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64Cyclic peptides containing only normal peptide links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
DK16172509.8T 2008-04-17 2009-04-16 Biologisk aktive peptider DK3115370T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US932608P 2008-04-17 2008-04-17
US11305508P 2008-11-10 2008-11-10
EP09743243.9A EP2279200B1 (en) 2008-04-17 2009-04-16 Biologically active peptides

Publications (1)

Publication Number Publication Date
DK3115370T3 true DK3115370T3 (da) 2019-07-29

Family

ID=40887122

Family Applications (2)

Application Number Title Priority Date Filing Date
DK16172509.8T DK3115370T3 (da) 2008-04-17 2009-04-16 Biologisk aktive peptider
DK09743243.9T DK2279200T3 (da) 2008-04-17 2009-04-16 Biologisk aktive peptider

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK09743243.9T DK2279200T3 (da) 2008-04-17 2009-04-16 Biologisk aktive peptider

Country Status (19)

Country Link
US (6) US8563688B2 (da)
EP (2) EP2279200B1 (da)
JP (3) JP6038452B2 (da)
KR (2) KR101434712B1 (da)
CN (2) CN102007140B (da)
AR (1) AR071478A1 (da)
AU (1) AU2009244635B2 (da)
BR (1) BRPI0911203A2 (da)
CA (1) CA2721694C (da)
DK (2) DK3115370T3 (da)
ES (2) ES2739676T3 (da)
HK (1) HK1223946A1 (da)
MX (1) MX2010011397A (da)
NZ (1) NZ588200A (da)
PL (1) PL2279200T3 (da)
PT (1) PT2279200T (da)
SG (2) SG10201809286XA (da)
TW (2) TWI541020B (da)
WO (1) WO2009137256A1 (da)

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TWI541020B (zh) * 2008-04-17 2016-07-11 巴克斯歐塔公司 生物活性胜肽
JP2013502458A (ja) 2009-08-24 2013-01-24 アムニクス オペレーティング インコーポレイテッド 凝固第vii因子組成物ならびにそれを製造および使用する方法
WO2012012444A2 (en) 2010-07-19 2012-01-26 Dolby Laboratories Licensing Corporation Enhancement methods for sampled and multiplexed image and video data
PL2717898T3 (pl) 2011-06-10 2019-06-28 Bioverativ Therapeutics Inc. Związki o działaniu prokoagulacyjnym i sposoby ich stosowania
PT3564260T (pt) 2012-02-15 2023-01-18 Bioverativ Therapeutics Inc Composições de fator viii e métodos de produção e utilização das mesmas
CA2864126A1 (en) 2012-02-15 2013-08-22 Biogen Idec Ma Inc. Recombinant factor viii proteins
CA2915389C (en) * 2013-06-11 2019-06-04 Cj Cheiljedang Corporation L-isoleucine-producing corynebacterium glutamicum strain and method of producing l-isoleucine therefrom
WO2015023894A1 (en) 2013-08-14 2015-02-19 Biogen Idec Ma Inc. Recombinant factor viii proteins
TWI667255B (zh) 2013-08-14 2019-08-01 美商生物化學醫療公司 因子viii-xten融合物及其用途
WO2015070014A1 (en) 2013-11-08 2015-05-14 Biogen Idec Ma Inc. Procoagulant fusion compound
US9321812B2 (en) 2014-03-28 2016-04-26 Perle Bioscience Insulin independence among patients with diabetes utilizing an optimized hamster REG3 gamma peptide
JP6484468B2 (ja) * 2014-06-03 2019-03-13 AvanStrate株式会社 ガラス板製造方法およびガラス板製造装置
GB201410507D0 (en) * 2014-06-12 2014-07-30 Univ Bath Drug delivery enhancement agents
EA201890423A1 (ru) 2015-08-03 2018-07-31 Биовератив Терапьютикс Инк. Слитые белки фактора ix, способы их получения и применения
AU2017336440B2 (en) 2016-09-28 2022-06-02 Cohbar, Inc. Therapeutic MOTS-c related peptides
JP7748175B2 (ja) 2016-12-02 2025-10-02 バイオベラティブ セラピューティクス インコーポレイテッド キメラ凝固因子を使用して血友病性関節症を処置する方法
BR112019015569A2 (pt) 2017-01-31 2020-03-17 Bioverativ Therapeutics Inc. Proteínas de fusão do fator ix e métodos para a sua produção e uso
CN112512555A (zh) 2018-05-18 2021-03-16 比奥维拉迪维治疗股份有限公司 治疗血友病a的方法

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US4447356A (en) * 1981-04-17 1984-05-08 Olivera Baldomero M Conotoxins
IT1190891B (it) 1982-06-24 1988-02-24 Anic Spa Metodo per la sintesi in fase solida di polipeptidi retroinvertiti
US5122614A (en) 1989-04-19 1992-06-16 Enzon, Inc. Active carbonates of polyalkylene oxides for modification of polypeptides
US5093317A (en) * 1989-06-05 1992-03-03 Cephalon, Inc. Treating disorders by application of insulin-like growth factor
JPH0725794B2 (ja) * 1990-03-23 1995-03-22 呉羽化学工業株式会社 新規なペプチド
US5595732A (en) 1991-03-25 1997-01-21 Hoffmann-La Roche Inc. Polyethylene-protein conjugates
US6037452A (en) 1992-04-10 2000-03-14 Alpha Therapeutic Corporation Poly(alkylene oxide)-Factor VIII or Factor IX conjugate
DK0693924T4 (da) 1993-02-22 2008-08-04 Abraxis Bioscience Inc Fremgangsmåde til (in vivo) levering af biologiske materialer og sammensætninger, der er egnede dertil
US5439686A (en) 1993-02-22 1995-08-08 Vivorx Pharmaceuticals, Inc. Methods for in vivo delivery of substantially water insoluble pharmacologically active agents and compositions useful therefor
AU711935B2 (en) * 1994-12-30 1999-10-21 Seminis Vegetable Seeds, Inc. Papaya ringspot virus replicase gene
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US7279548B2 (en) * 1996-04-03 2007-10-09 Cytogen Corporation Identification and isolation of novel polypeptides having WW domains and methods of using same
US6197526B1 (en) 1999-01-04 2001-03-06 Dyax Corp. Polypeptides for binding human factor VIII and fragments of human factor VIII
US6624289B1 (en) 1999-06-16 2003-09-23 Saint Louis University Region of factor IXa protease domain that interacts with factor VIIIa and methods therefor
US7109170B2 (en) 1999-06-16 2006-09-19 Saint Louis University Region of factor IXa protease domain that interacts with factor VIIIa and methods therefor
JP2003503426A (ja) 1999-07-02 2003-01-28 ジェネンテック・インコーポレーテッド FVIIaアンタゴニスト
AT411997B (de) 1999-09-14 2004-08-26 Baxter Ag Faktor ix/faktor ixa aktivierende antikörper und antikörper-derivate
AU2065801A (en) * 1999-12-06 2001-06-12 Panacea Pharmaceuticals, Llc Passive desensitization
US20020197266A1 (en) * 2000-02-08 2002-12-26 Waldemar Debinski Immunotherapy using interleukin 13 receptor subunit alpha 2
AU2002256518B2 (en) * 2001-05-11 2007-07-19 Research Development Foundation Inhibitors of receptor activator of NF-kappaB and uses thereof
FR2830865B1 (fr) * 2001-10-17 2004-10-22 Centre Nat Rech Scient Leurres peptidiques pour la preparation de medicaments destines a la prevention ou au traitement des pathologies auto-immunes, ou des troubles lies a l'apparition d'anticorps diriges contre des proteines exogenes
US20060204503A1 (en) * 2005-01-31 2006-09-14 Biogen Idec Ma Inc. Treatment of cancer using antibodies to polypeptides differentially expressed in human lung tumors
CA2632714A1 (en) * 2005-12-07 2007-06-14 Technische Universitaet Muenchen Small peptidic and peptido-mimetic affinity ligands for factor viii and factor viii-like proteins
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TWI541020B (zh) * 2008-04-17 2016-07-11 巴克斯歐塔公司 生物活性胜肽

Also Published As

Publication number Publication date
US20120077749A1 (en) 2012-03-29
NZ588200A (en) 2012-11-30
TW200944226A (en) 2009-11-01
US20190225648A1 (en) 2019-07-25
PL2279200T3 (pl) 2017-08-31
AU2009244635A1 (en) 2009-11-12
US8563688B2 (en) 2013-10-22
US10287319B2 (en) 2019-05-14
DK2279200T3 (da) 2016-08-22
US20150038676A1 (en) 2015-02-05
ES2594706T3 (es) 2016-12-22
JP2014074052A (ja) 2014-04-24
CA2721694C (en) 2018-11-06
US20160060295A1 (en) 2016-03-03
US9598464B2 (en) 2017-03-21
CN105524163A (zh) 2016-04-27
JP5977223B2 (ja) 2016-08-24
KR20130112959A (ko) 2013-10-14
EP2279200A1 (en) 2011-02-02
TW201443085A (zh) 2014-11-16
TWI541020B (zh) 2016-07-11
ES2739676T3 (es) 2020-02-03
CN102007140A (zh) 2011-04-06
SG10201809286XA (en) 2018-11-29
HK1223946A1 (zh) 2017-08-11
US20100022445A1 (en) 2010-01-28
JP2011518179A (ja) 2011-06-23
TWI573806B (zh) 2017-03-11
JP2017019797A (ja) 2017-01-26
MX2010011397A (es) 2010-11-12
KR101606248B1 (ko) 2016-03-24
KR101434712B1 (ko) 2014-10-01
CN102007140B (zh) 2016-02-24
AR071478A1 (es) 2010-06-23
BRPI0911203A2 (pt) 2016-07-05
US8822638B2 (en) 2014-09-02
US10822376B2 (en) 2020-11-03
HK1154255A1 (zh) 2012-04-13
CA2721694A1 (en) 2009-11-12
EP3115370A1 (en) 2017-01-11
SG10201608071YA (en) 2016-11-29
US9206234B2 (en) 2015-12-08
WO2009137256A1 (en) 2009-11-12
EP2279200B1 (en) 2016-07-13
KR20110005873A (ko) 2011-01-19
AU2009244635B2 (en) 2012-04-19
PT2279200T (pt) 2016-10-12
US20170174724A1 (en) 2017-06-22
EP3115370B1 (en) 2019-06-26
JP6038452B2 (ja) 2016-12-07

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