DK3019166T3 - A Pharmaceutical Combination for the Treatment of Melanoma - Google Patents
A Pharmaceutical Combination for the Treatment of Melanoma Download PDFInfo
- Publication number
- DK3019166T3 DK3019166T3 DK14822283.9T DK14822283T DK3019166T3 DK 3019166 T3 DK3019166 T3 DK 3019166T3 DK 14822283 T DK14822283 T DK 14822283T DK 3019166 T3 DK3019166 T3 DK 3019166T3
- Authority
- DK
- Denmark
- Prior art keywords
- melanoma
- treatment
- pharmaceutical combination
- pharmaceutical
- combination
- Prior art date
Links
- 201000001441 melanoma Diseases 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361845749P | 2013-07-12 | 2013-07-12 | |
| PCT/IB2014/063022 WO2015004636A1 (en) | 2013-07-12 | 2014-07-11 | A pharmaceutical combination for the treatment of melanoma |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3019166T3 true DK3019166T3 (da) | 2019-07-29 |
Family
ID=52279411
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK14822283.9T DK3019166T3 (da) | 2013-07-12 | 2014-07-11 | A Pharmaceutical Combination for the Treatment of Melanoma |
Country Status (12)
| Country | Link |
|---|---|
| US (4) | US11007174B2 (da) |
| EP (1) | EP3019166B1 (da) |
| JP (5) | JP6568060B2 (da) |
| CN (3) | CN105530931B (da) |
| AR (1) | AR096892A1 (da) |
| AU (1) | AU2014288857B2 (da) |
| CA (1) | CA2917742C (da) |
| DK (1) | DK3019166T3 (da) |
| ES (1) | ES2733929T3 (da) |
| IL (1) | IL243572B (da) |
| TW (4) | TWI839690B (da) |
| WO (1) | WO2015004636A1 (da) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3019166B1 (en) | 2013-07-12 | 2019-05-08 | Piramal Enterprises Limited | A pharmaceutical combination for the treatment of melanoma |
| CN108135896A (zh) * | 2015-06-05 | 2018-06-08 | 伊利诺伊大学董事会 | Pac-1联合疗法 |
| EP4272735B1 (en) * | 2015-06-30 | 2025-06-18 | Genentech, Inc. | Immediate-release tablets containing a drug and processes for forming the tablets |
| AU2017232496B2 (en) * | 2016-03-16 | 2022-11-24 | Dicerna Pharmaceuticals, Inc. | Compositions and methods for the treatment of a beta-catenin-associated disease or disorder |
| JP7300394B2 (ja) | 2017-01-17 | 2023-06-29 | ヘパリジェニックス ゲーエムベーハー | 肝再生の促進又は肝細胞死の低減もしくは予防のためのプロテインキナーゼ阻害 |
| CN116036278B (zh) * | 2017-05-16 | 2024-12-17 | 生物医学谷探索股份有限公司 | 用于治疗具有非典型braf突变的癌症的组合物和方法 |
| EP3710433A4 (en) | 2017-11-17 | 2022-01-12 | The Board of Trustees of the University of Illinois | CANCER THERAPY BY REMOVAL OF DOUBLE MEK SIGNALING |
| CN107827726B (zh) * | 2017-11-28 | 2020-09-15 | 辽宁中医药大学 | 马齿苋中化合物Oleracone E及其提取分离方法 |
| CN108591464B (zh) * | 2018-06-28 | 2020-06-23 | 宁波奥克斯高科技有限公司 | 一种气体绝缘开关柜用密封结构 |
| CN113329749B (zh) * | 2018-10-05 | 2025-02-11 | 伊利诺伊大学董事会 | 用于治疗葡萄膜黑色素瘤的联合疗法 |
| WO2020210760A1 (en) * | 2019-04-11 | 2020-10-15 | Mei Pharma, Inc. | Voruciclib poly morphs and methods of making and using thereof |
| CN115551509A (zh) * | 2020-05-12 | 2022-12-30 | 诺华股份有限公司 | 包含craf抑制剂的治疗组合 |
| CN112168821B (zh) * | 2020-11-09 | 2022-10-14 | 中南大学湘雅医院 | 一种治疗维罗非尼耐药的黑色素瘤的联合用药物及其应用 |
| CN117043159A (zh) * | 2020-11-19 | 2023-11-10 | 梅制药公司 | Kras突变型癌症的治疗 |
| EP4247806A4 (en) * | 2020-11-19 | 2024-11-13 | MEI Pharma, Inc. | TREATMENT OF KRAS-MUTANT CANCERS |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IN164232B (da) | 1986-04-11 | 1989-02-04 | Hoechst India | |
| USH1427H (en) | 1988-04-06 | 1995-04-04 | Briet; Phillipe | Substituted flavonoid compounds, their salts, their manufacture and their use in combination with interleukin-2 |
| US5116954A (en) | 1988-04-06 | 1992-05-26 | Lipha, Lyonnaise Industrielle Pharmaceutique | Pharmaceutically useful flavonoic compounds containing at least one substituent on the benzopyranone ring moiety |
| US5284856A (en) | 1988-10-28 | 1994-02-08 | Hoechst Aktiengesellschaft | Oncogene-encoded kinases inhibition using 4-H-1-benzopyran-4-one derivatives |
| US5723313A (en) | 1995-09-27 | 1998-03-03 | St. Jude Children's Research Hospital | ARF-p19, a novel regulator of the mammalian cell cycle |
| US5733920A (en) | 1995-10-31 | 1998-03-31 | Mitotix, Inc. | Inhibitors of cyclin dependent kinases |
| US5849733A (en) | 1996-05-10 | 1998-12-15 | Bristol-Myers Squibb Co. | 2-thio or 2-oxo flavopiridol analogs |
| US6281223B1 (en) | 1999-04-13 | 2001-08-28 | Supergen, Inc. | Radioenhanced camptothecin derivative cancer treatments |
| HUP0300382A3 (en) | 2000-03-29 | 2006-11-28 | Cyclacel Ltd | 2-substituted 4-heteroaryl-pyrimidines and their use in the treatmetn of proliferative disorders and pharmaceutical compositions containing the compounds |
| US6683095B2 (en) | 2000-05-03 | 2004-01-27 | Lg Life Sciences Ltd. | CDK inhibitors having 3-hydroxychromen-4-one structure |
| AU2001271639A1 (en) | 2000-06-28 | 2002-01-08 | Teva Pharmaceutical Industries Ltd. | Carvedilol |
| US7915301B2 (en) | 2002-07-08 | 2011-03-29 | Piramal Life Science Limited | Inhibitors of cyclin dependent kinases and their use |
| US7884127B2 (en) | 2002-07-08 | 2011-02-08 | Pirimal Life Sciences Ltd. | Inhibitors of cyclin dependent kinases and their use |
| US7271193B2 (en) * | 2002-07-08 | 2007-09-18 | Nicholas Piramal India, Ltd. | Inhibitors of cyclin-dependent kinases and their use |
| TWI331034B (en) * | 2002-07-08 | 2010-10-01 | Piramal Life Sciences Ltd | Inhibitors of cyclin-dependent kinases and their use |
| EP1558289A1 (en) | 2002-11-06 | 2005-08-03 | Cyclacel Limited | Pharmaceutical composition comprising a cdk inhibitor and gemcitabine |
| GB0328180D0 (en) | 2003-12-04 | 2004-01-07 | Cyclacel Ltd | Combination |
| CA2548491A1 (en) | 2003-12-08 | 2005-06-23 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Synergistic anti-cancer compositions |
| JP2008533039A (ja) | 2005-03-11 | 2008-08-21 | ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン | 抗アポトーシスＢｃｌ−２ファミリーメンバーのクロメン−４−オン阻害剤およびその使用 |
| WO2007002325A1 (en) * | 2005-06-22 | 2007-01-04 | Plexxikon, Inc. | Pyrrolo[2,3-b] pyridine derivatives as protein kinase inhibitors |
| KR101209397B1 (ko) | 2006-06-21 | 2012-12-06 | 피라말 라이프 사이언시스 리미티드 | 증식성 질환 치료용 광학이성적으로 순수한, 증식성 질환 치료용 플라본 유도체 및 이의 제조방법 |
| CN101484445B (zh) | 2006-07-07 | 2012-09-05 | 皮瑞缪生命科学有限公司 | 吡咯烷取代的黄酮的对映选择性合成 |
| GB0706633D0 (en) | 2007-04-04 | 2007-05-16 | Cyclacel Ltd | Combination |
| DK2154971T3 (da) * | 2007-05-15 | 2012-04-02 | Piramal Life Sciences Ltd | Synergistisk farmaceutisk kombination til behandling af cancer |
| US20100152129A1 (en) | 2008-03-31 | 2010-06-17 | Periyasamy Giridharan | Novel synergistic combination of gemcitabine with P276-00 or P1446A in treatment of cancer |
| TWI461194B (zh) | 2009-05-05 | 2014-11-21 | Piramal Entpr Ltd | 吡咯啶取代黃酮作為輻射致敏劑 |
| US8906953B2 (en) | 2010-02-26 | 2014-12-09 | Piramal Enterprises Limited | Pyrrolidine substitute flavones for the treatment of inflammatory disorders |
| CN101841463B (zh) * | 2010-03-05 | 2012-05-16 | 清华大学 | 基于sctp的多路径并发传输方法 |
| JP5903433B2 (ja) * | 2010-08-26 | 2016-04-13 | ノバルティス アーゲー | 癌の治療に有用なｖｅｇｆｒ阻害剤およびｍｅｋ阻害剤の医薬的組み合わせ |
| CN103402517A (zh) | 2010-11-19 | 2013-11-20 | 葛兰素史密斯克莱知识产权（第2号）有限公司 | 使用braf抑制剂的治疗方法 |
| CA2818229A1 (en) | 2010-11-19 | 2012-05-24 | Piramal Enterprises Limited | Pharmaceutical combination of paclitaxel and a cdk inhibitor |
| TW201242597A (en) * | 2011-03-14 | 2012-11-01 | Piramal Life Sciences Ltd | A synergistic pharmaceutical combination for the treatment of pancreatic cancer |
| TW201300105A (zh) | 2011-05-31 | 2013-01-01 | Piramal Life Sciences Ltd | 治療頭頸鱗狀細胞癌之相乘藥物組合物 |
| US20120321637A1 (en) * | 2011-06-20 | 2012-12-20 | The Board Of Regents Of The University Of Texas System | Combination cancer therapy with herv inhibition |
| CN103648588A (zh) | 2011-06-24 | 2014-03-19 | 皮拉马尔企业有限公司 | 治疗人类乳头状瘤病毒相关癌症的化合物 |
| US20140348950A1 (en) | 2012-01-13 | 2014-11-27 | Piramal Enterprises Limited | Pyrrolidine- substituted flavone derivatives for prevention or treatment of oral mucositis |
| WO2014049515A1 (en) | 2012-09-25 | 2014-04-03 | Piramal Enterprises Limited | Pyrrolidine substituted flavones for treatment of renal cystic diseases |
| WO2014128523A1 (en) | 2013-02-19 | 2014-08-28 | Piramal Enterprises Limited | A process for preparation of an intermediate of the pyrrolidine substituted flavones |
| EP3019166B1 (en) | 2013-07-12 | 2019-05-08 | Piramal Enterprises Limited | A pharmaceutical combination for the treatment of melanoma |
| ES2873959T3 (es) | 2014-05-28 | 2021-11-04 | Piramal Entpr Ltd | Combinación farmacéutica que comprende un inhibidor de CDK y un inhibidor de tiorredoxina reductasa para el tratamiento del cáncer |
-
2014
- 2014-07-11 EP EP14822283.9A patent/EP3019166B1/en active Active
- 2014-07-11 TW TW111106633A patent/TWI839690B/zh active
- 2014-07-11 US US14/904,407 patent/US11007174B2/en active Active
- 2014-07-11 JP JP2016524936A patent/JP6568060B2/ja active Active
- 2014-07-11 CA CA2917742A patent/CA2917742C/en active Active
- 2014-07-11 CN CN201480050507.6A patent/CN105530931B/zh active Active
- 2014-07-11 WO PCT/IB2014/063022 patent/WO2015004636A1/en not_active Ceased
- 2014-07-11 TW TW113110009A patent/TW202502325A/zh unknown
- 2014-07-11 ES ES14822283T patent/ES2733929T3/es active Active
- 2014-07-11 TW TW108142557A patent/TW202031253A/zh unknown
- 2014-07-11 TW TW103123951A patent/TWI680760B/zh active
- 2014-07-11 AU AU2014288857A patent/AU2014288857B2/en active Active
- 2014-07-11 CN CN201911007262.XA patent/CN111053768B/zh active Active
- 2014-07-11 AR ARP140102577A patent/AR096892A1/es not_active Application Discontinuation
- 2014-07-11 DK DK14822283.9T patent/DK3019166T3/da active
- 2014-07-11 CN CN202311581824.8A patent/CN117731786A/zh active Pending
-
2016
- 2016-01-11 IL IL24357216A patent/IL243572B/en active IP Right Grant
-
2018
- 2018-12-13 US US16/218,576 patent/US20190282544A1/en not_active Abandoned
-
2019
- 2019-08-01 JP JP2019141995A patent/JP2019206565A/ja active Pending
-
2020
- 2020-09-10 JP JP2020152028A patent/JP2021001186A/ja active Pending
-
2021
- 2021-02-05 US US17/168,876 patent/US11839591B2/en active Active
-
2022
- 2022-02-24 JP JP2022026851A patent/JP7799508B2/ja active Active
-
2023
- 2023-10-30 US US18/497,653 patent/US12383530B2/en active Active
- 2023-12-14 JP JP2023210858A patent/JP2024037891A/ja active Pending
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK3019166T3 (da) | A Pharmaceutical Combination for the Treatment of Melanoma | |
| HUE046964T2 (hu) | Kombinált gyógyászati készítmény | |
| IL240388A0 (en) | Methods of treating melanoma | |
| HUE037275T2 (hu) | Gyógyszer-kombináció | |
| LT3080100T (lt) | Lizinui specifinės demetilazės-1 inhibitoriai | |
| EP2968894A4 (en) | MEDICAL CONNECTOR | |
| DK2970389T3 (da) | Farmaceutiske forbindelser | |
| BR112016009485A2 (pt) | Inalador de medicamento | |
| LT2981255T (lt) | Empagliflozino terapiniai panaudojimo būdai | |
| HRP20190101T1 (hr) | Terapeutske uporabe empagliflozina | |
| DOS2013000177S (es) | Capsulas | |
| DK2767269T3 (da) | Terapeutisk anordning | |
| LT3563837T (lt) | Terapija bakteriofagu | |
| DK3079655T3 (da) | Inhalerbare lægemidler | |
| DK3079667T3 (da) | Farmaceutiske doseringsformer | |
| HRP20181307T1 (hr) | Postupak izrade zubne proteze | |
| DK3003401T3 (da) | Farmaceutisk præparat | |
| LT3046537T (lt) | Farmacinis angliavandenių preparatas, skirtas terapiniam panaudojimui | |
| DK2976101T3 (da) | Behandlingsfremgangsmåde | |
| DK2897588T3 (da) | Inhalerbart lægemiddel | |
| EP2992915A4 (en) | MEDICAL HELP | |
| DK3041506T3 (da) | Behandlingsfremgangsmåde | |
| FI20136034A7 (fi) | Sauna | |
| UA28330S (uk) | Капсула для лікарського засобу | |
| UA28338S (uk) | Медичний пристрій-шприц |