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DK286990D0 - Indanderivater - Google Patents

Indanderivater

Info

Publication number
DK286990D0
DK286990D0 DK286990A DK286990A DK286990D0 DK 286990 D0 DK286990 D0 DK 286990D0 DK 286990 A DK286990 A DK 286990A DK 286990 A DK286990 A DK 286990A DK 286990 D0 DK286990 D0 DK 286990D0
Authority
DK
Denmark
Prior art keywords
optionally substituted
alkyl
hydroxy
hydrogen
cycloalkyl
Prior art date
Application number
DK286990A
Other languages
Danish (da)
English (en)
Inventor
Klaus Boegesoe
Peter Bregnedal
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Priority to DK286990A priority Critical patent/DK286990D0/da
Publication of DK286990D0 publication Critical patent/DK286990D0/da
Priority to IE407691A priority patent/IE914076A1/en
Priority to NZ240734A priority patent/NZ240734A/en
Priority to IL10016491A priority patent/IL100164A/en
Priority to KR1019930701680A priority patent/KR930702980A/ko
Priority to CA002097715A priority patent/CA2097715C/en
Priority to AT92900941T priority patent/ATE121294T1/de
Priority to DE69109132T priority patent/DE69109132T2/de
Priority to PCT/DK1991/000358 priority patent/WO1992010192A1/en
Priority to EP92900941A priority patent/EP0560868B1/en
Priority to ES92900941T priority patent/ES2071479T3/es
Priority to JP50028192A priority patent/JP3245418B2/ja
Priority to DK92900941.3T priority patent/DK0560868T3/da
Priority to AU89599/91A priority patent/AU653375B2/en
Priority to PT99673A priority patent/PT99673B/pt
Priority to ZA919563A priority patent/ZA919563B/xx
Priority to NO932024A priority patent/NO179947C/no
Priority to FI932541A priority patent/FI105685B/fi
Priority to US08/383,708 priority patent/US5643784A/en
Priority to HK122995A priority patent/HK122995A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24Oxygen or sulfur atoms
    • C07D207/262-Pyrrolidones
    • C07D207/2632-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24Oxygen or sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30Oxygen or sulfur atoms
    • C07D233/42Sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/26Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/06Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D239/08Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms directly attached in position 2
    • C07D239/10Oxygen or sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18Oxygen atoms
    • C07D263/20Oxygen atoms attached in position 2
    • C07D263/22Oxygen atoms attached in position 2 with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to other ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/06Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
    • C07D295/073Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Fats And Perfumes (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pyrrole Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK286990A 1990-12-04 1990-12-04 Indanderivater DK286990D0 (da)

Priority Applications (20)

Application Number Priority Date Filing Date Title
DK286990A DK286990D0 (da) 1990-12-04 1990-12-04 Indanderivater
IE407691A IE914076A1 (en) 1990-12-04 1991-11-22 Indan derivatives
NZ240734A NZ240734A (en) 1990-12-04 1991-11-26 5-substituted-trans-1-piperazinoindan derivatives; their preparation and
IL10016491A IL100164A (en) 1990-12-04 1991-11-27 5-substituted-1-piperazinoindan derivatives method for their preparation and pharmaceutical preparations and medicaments containing them
AU89599/91A AU653375B2 (en) 1990-12-04 1991-11-28 Indan derivatives
PCT/DK1991/000358 WO1992010192A1 (en) 1990-12-04 1991-11-28 Indan derivatives
JP50028192A JP3245418B2 (ja) 1990-12-04 1991-11-28 インダン誘導体
AT92900941T ATE121294T1 (de) 1990-12-04 1991-11-28 Indanderivate.
DE69109132T DE69109132T2 (de) 1990-12-04 1991-11-28 Indanderivate.
KR1019930701680A KR930702980A (ko) 1990-12-04 1991-11-28 인단 유도체
EP92900941A EP0560868B1 (en) 1990-12-04 1991-11-28 Indan derivatives
ES92900941T ES2071479T3 (es) 1990-12-04 1991-11-28 Derivados de indano.
CA002097715A CA2097715C (en) 1990-12-04 1991-11-28 Indan derivatives
DK92900941.3T DK0560868T3 (da) 1990-12-04 1991-11-28 Indan derivater
PT99673A PT99673B (pt) 1990-12-04 1991-12-03 Processo para a preparacao de derivados de 1-piperazino-indano e de composicoes farmaceuticas que os contem
ZA919563A ZA919563B (en) 1990-12-04 1991-12-04 Indan derivatives
NO932024A NO179947C (no) 1990-12-04 1993-06-03 Indanderivater
FI932541A FI105685B (fi) 1990-12-04 1993-06-03 Menetelmä uusien terapeuttisesti käyttökelpoisten 5-substituoitujen trans-1-piperatsinoindaanijohdannaisten ja niiden farmaseuttisesti hyväksyttävien happoadditiosuolojen valmistamiseksi
US08/383,708 US5643784A (en) 1990-12-04 1995-02-01 Indan derivatives
HK122995A HK122995A (en) 1990-12-04 1995-07-27 Indan derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK286990A DK286990D0 (da) 1990-12-04 1990-12-04 Indanderivater

Publications (1)

Publication Number Publication Date
DK286990D0 true DK286990D0 (da) 1990-12-04

Family

ID=8116621

Family Applications (2)

Application Number Title Priority Date Filing Date
DK286990A DK286990D0 (da) 1990-12-04 1990-12-04 Indanderivater
DK92900941.3T DK0560868T3 (da) 1990-12-04 1991-11-28 Indan derivater

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK92900941.3T DK0560868T3 (da) 1990-12-04 1991-11-28 Indan derivater

Country Status (18)

Country Link
EP (1) EP0560868B1 (no)
JP (1) JP3245418B2 (no)
KR (1) KR930702980A (no)
AT (1) ATE121294T1 (no)
AU (1) AU653375B2 (no)
CA (1) CA2097715C (no)
DE (1) DE69109132T2 (no)
DK (2) DK286990D0 (no)
ES (1) ES2071479T3 (no)
FI (1) FI105685B (no)
HK (1) HK122995A (no)
IE (1) IE914076A1 (no)
IL (1) IL100164A (no)
NO (1) NO179947C (no)
NZ (1) NZ240734A (no)
PT (1) PT99673B (no)
WO (1) WO1992010192A1 (no)
ZA (1) ZA919563B (no)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ243065A (en) * 1991-06-13 1995-07-26 Lundbeck & Co As H Piperidine derivatives and pharmaceutical compositions
DK55192D0 (da) * 1992-04-28 1992-04-28 Lundbeck & Co As H 1-piperazino-1,2-dihydroindenderivater
DK78692D0 (da) * 1992-06-12 1992-06-12 Lundbeck & Co As H Dimere piperidin- og piperazinderivater
SK94393A3 (en) * 1992-09-11 1994-08-10 Thomae Gmbh Dr K Cyclic derivatives of urea, process for their production and their pharmaceutical agents with the content of those
JP2000514060A (ja) * 1996-07-01 2000-10-24 シェーリング コーポレイション ムスカリン様アンタゴニスト
US5935958A (en) * 1996-07-01 1999-08-10 Schering Corporation Muscarinic antagonists
TWI242011B (en) 1997-03-31 2005-10-21 Eisai Co Ltd 1,4-substituted cyclic amine derivatives
IS7282A (is) * 2001-12-21 2004-05-21 H. Lundbeck A/S Amínóindan afleiður sem serótónín og noradrenalínupptökuhindrar
MXPA04006119A (es) * 2001-12-21 2004-11-01 Lundbeck & Co As H Derivados aminoindano como inhibidores de la absorcion de la serotonina y de la norepinefrina.
FR2883876B1 (fr) * 2005-03-30 2007-05-04 Servier Lab Derives d'indanyl-piperazines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
TW200819426A (en) 2006-08-31 2008-05-01 Lundbeck & Co As H Novel indane compounds
KR101939546B1 (ko) 2011-06-20 2019-01-16 하. 룬드벡 아크티에셀스카브 정신 분열증의 치료를 위한 중수소화 1-피페라지노-3-페닐 인단
CN113056457B (zh) * 2018-12-03 2025-06-20 H.隆德贝克有限公司 用于治疗cns疾病的前药

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE50867B1 (en) * 1980-02-29 1986-08-06 Kefalas As Indane derivatives
GB8427125D0 (en) * 1984-10-26 1984-12-05 Lundbeck & Co As H Organic compounds

Also Published As

Publication number Publication date
CA2097715C (en) 2003-04-15
DE69109132T2 (de) 1995-08-31
NO179947C (no) 1997-01-15
NO179947B (no) 1996-10-07
DK0560868T3 (da) 1995-10-02
ZA919563B (en) 1992-08-26
WO1992010192A1 (en) 1992-06-25
AU8959991A (en) 1992-07-08
NZ240734A (en) 1994-02-25
CA2097715A1 (en) 1992-06-05
KR930702980A (ko) 1993-11-29
IL100164A0 (en) 1992-08-18
JPH06503073A (ja) 1994-04-07
IL100164A (en) 1996-06-18
PT99673B (pt) 1999-05-31
NO932024L (no) 1993-07-30
IE914076A1 (en) 1992-06-17
FI105685B (fi) 2000-09-29
PT99673A (pt) 1992-10-30
EP0560868B1 (en) 1995-04-19
DE69109132D1 (de) 1995-05-24
AU653375B2 (en) 1994-09-29
EP0560868A1 (en) 1993-09-22
HK122995A (en) 1995-08-04
ES2071479T3 (es) 1995-06-16
NO932024D0 (no) 1993-06-03
ATE121294T1 (de) 1995-05-15
FI932541A7 (fi) 1993-07-23
JP3245418B2 (ja) 2002-01-15
FI932541A0 (fi) 1993-06-03

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