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DK2702147T3 - Fremgangsmåder til oprensning af vira ved hjælp af gelpermeationskromatografi - Google Patents

Fremgangsmåder til oprensning af vira ved hjælp af gelpermeationskromatografi Download PDF

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Publication number
DK2702147T3
DK2702147T3 DK12776970.1T DK12776970T DK2702147T3 DK 2702147 T3 DK2702147 T3 DK 2702147T3 DK 12776970 T DK12776970 T DK 12776970T DK 2702147 T3 DK2702147 T3 DK 2702147T3
Authority
DK
Denmark
Prior art keywords
vira
cleaning
methods
gel permeation
permeation chromatography
Prior art date
Application number
DK12776970.1T
Other languages
English (en)
Inventor
Matthew C Coffey
Allison Hagerman
Roxna Kapadia
Sarah Serl
Original Assignee
Oncolytics Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oncolytics Biotech Inc filed Critical Oncolytics Biotech Inc
Application granted granted Critical
Publication of DK2702147T3 publication Critical patent/DK2702147T3/da

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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/34Size-selective separation, e.g. size-exclusion chromatography; Gel filtration; Permeation
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/42Selective adsorption, e.g. chromatography characterised by the development mode, e.g. by displacement or by elution
    • B01D15/424Elution mode
    • B01D15/426Specific type of solvent
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/02Separating microorganisms from their culture media
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011Details
    • C12N2720/12011Reoviridae
    • C12N2720/12051Methods of production or purification of viral material

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Medicinal Preparation (AREA)
DK12776970.1T 2011-04-29 2012-04-27 Fremgangsmåder til oprensning af vira ved hjælp af gelpermeationskromatografi DK2702147T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161480561P 2011-04-29 2011-04-29
PCT/CA2012/000406 WO2012145837A1 (en) 2011-04-29 2012-04-27 Methods of purifying viruses using gel permeation chromatography

Publications (1)

Publication Number Publication Date
DK2702147T3 true DK2702147T3 (da) 2020-09-28

Family

ID=47067091

Family Applications (1)

Application Number Title Priority Date Filing Date
DK12776970.1T DK2702147T3 (da) 2011-04-29 2012-04-27 Fremgangsmåder til oprensning af vira ved hjælp af gelpermeationskromatografi

Country Status (15)

Country Link
US (1) US20120273424A1 (da)
EP (1) EP2702147B1 (da)
JP (1) JP6029651B2 (da)
KR (2) KR102151890B1 (da)
CN (1) CN103492557B (da)
AU (1) AU2012248082B2 (da)
CA (1) CA2832367A1 (da)
DK (1) DK2702147T3 (da)
EA (1) EA201391605A1 (da)
ES (1) ES2822199T3 (da)
IL (1) IL228491A (da)
MX (1) MX337348B (da)
SG (1) SG194449A1 (da)
TW (1) TW201307561A (da)
WO (1) WO2012145837A1 (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA201390812A1 (ru) 2010-12-02 2013-11-29 Онколитикс Байотек Инк. Лиофилизированные вирусные составы
EA201390810A1 (ru) * 2010-12-02 2013-09-30 Онколитикс Байотек Инк. Жидкие вирусные составы
DK3010537T3 (da) * 2013-06-17 2018-09-24 De Staat Der Nederlanden Vert Door De Mini Van Vws Mini Van Volksgezondheit Welzijn En Sport Fremgangsmåde til forebyggelse af aggregation af viruskomponenter
US11999975B2 (en) 2018-07-04 2024-06-04 Probiogen Ag Method for purifying an enveloped virus
CN111812313B (zh) * 2020-06-22 2021-10-08 北京生物制品研究所有限责任公司 铝佐剂吸附型新型冠状病毒灭活疫苗中抗原的解离方法
CN114544815B (zh) * 2022-03-01 2023-10-27 中牧实业股份有限公司 一种山羊痘病毒的定量检测方法
CN116718524B (zh) * 2023-06-26 2025-11-07 西安交通大学 一种基于细胞膜色谱技术的病毒颗粒检测方法
HUP2400154A1 (hu) * 2024-02-29 2025-09-28 Pecsi Tudomanyegyetem Elúciós oldat és tisztítási eljárás

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5096885A (en) * 1988-04-15 1992-03-17 Genentech, Inc. Human growth hormone formulation
EP0410207B1 (en) * 1989-07-24 1997-01-22 Bayer Corporation Stabilization of highly purified proteins
WO1995031532A1 (en) * 1994-05-16 1995-11-23 Merck & Co., Inc. Papillomavirus vaccines
ES2290613T3 (es) * 1998-02-17 2008-02-16 Schering Corporation Composiciones que comprenden virus y metodos para concentrar preparaciones de virus.
WO2002074940A1 (en) 2001-03-16 2002-09-26 Oncolytics Biotech, Inc. Method of extracting virus from cell culture
NZ535944A (en) 2002-04-30 2007-11-30 Oncolytics Biotech Inc Viral purification method comprising a simple extraction step in which a detergent is directly added to the cell culture, thereafter, cell debris is removed from the extraction mixture by filtration or centrifugation
US7901921B2 (en) 2004-10-22 2011-03-08 Oncolytics Biotech Inc. Viral purification methods
EP1878791A1 (en) * 2006-07-11 2008-01-16 Bia Separations D.O.O. Method for influenza virus purification
US8030020B2 (en) * 2006-08-07 2011-10-04 Juridicial Foundation The Chemo-Sero-Therapeutic Research Institute Process for preparing live smallpox vaccine
MX2009009598A (es) * 2007-03-12 2009-09-21 Oncolytics Biotech Inc Reovirus que tienen secuencias modificadas.
DK2220116T3 (da) * 2007-11-12 2012-11-26 Theraclone Sciences Inc Sammensætninger og fremgangsmåder til terapien og diagnosticeringen af influenza
US8227577B2 (en) * 2007-12-21 2012-07-24 Hoffman-La Roche Inc. Bivalent, bispecific antibodies
EA201390812A1 (ru) * 2010-12-02 2013-11-29 Онколитикс Байотек Инк. Лиофилизированные вирусные составы
EA201390810A1 (ru) * 2010-12-02 2013-09-30 Онколитикс Байотек Инк. Жидкие вирусные составы

Also Published As

Publication number Publication date
CA2832367A1 (en) 2012-11-01
KR20190026059A (ko) 2019-03-12
CN103492557A (zh) 2014-01-01
JP2014516515A (ja) 2014-07-17
AU2012248082A1 (en) 2013-05-09
US20120273424A1 (en) 2012-11-01
WO2012145837A1 (en) 2012-11-01
MX337348B (es) 2016-02-29
KR102151890B1 (ko) 2020-09-03
AU2012248082B2 (en) 2015-08-20
EA201391605A1 (ru) 2014-02-28
MX2013012627A (es) 2014-05-13
IL228491A (en) 2017-05-29
EP2702147A4 (en) 2014-11-05
EP2702147B1 (en) 2020-07-15
KR20140024406A (ko) 2014-02-28
ES2822199T3 (es) 2021-04-29
JP6029651B2 (ja) 2016-11-24
TW201307561A (zh) 2013-02-16
EP2702147A1 (en) 2014-03-05
CN103492557B (zh) 2015-07-29
IL228491A0 (en) 2013-12-31
SG194449A1 (en) 2013-12-30

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DK2702147T3 (da) Fremgangsmåder til oprensning af vira ved hjælp af gelpermeationskromatografi