DK227183D0 - Fremgangsmade til fremstilling af imidazo (1,2-c)-pyrazolo(3,4-e) pyrimidiner med den almene formel i - Google Patents
Fremgangsmade til fremstilling af imidazo (1,2-c)-pyrazolo(3,4-e) pyrimidiner med den almene formel iInfo
- Publication number
- DK227183D0 DK227183D0 DK2271/83A DK227183A DK227183D0 DK 227183 D0 DK227183 D0 DK 227183D0 DK 2271/83 A DK2271/83 A DK 2271/83A DK 227183 A DK227183 A DK 227183A DK 227183 D0 DK227183 D0 DK 227183D0
- Authority
- DK
- Denmark
- Prior art keywords
- pyrazolo
- pyrimidines
- general formula
- preparing imidazo
- imidazo
- Prior art date
Links
- 150000003230 pyrimidines Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/38—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/16—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/38—Nitrogen atoms
- C07D231/40—Acylated on said nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/381,484 US4469868A (en) | 1982-05-24 | 1982-05-24 | Alkylimidazo[1,2-c]pyrazolo[3,4-e]pyrimidines |
| US38148482 | 1982-05-24 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| DK227183D0 true DK227183D0 (da) | 1983-05-20 |
| DK227183A DK227183A (da) | 1983-11-25 |
| DK161968B DK161968B (da) | 1991-09-02 |
| DK161968C DK161968C (da) | 1992-02-03 |
Family
ID=23505215
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK227183A DK161968C (da) | 1982-05-24 | 1983-05-20 | Analogifremgangsmaade til fremstilling af imidazo-pyrazolo-pyrimidiner eller farmaceutisk acceptable salte deraf |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US4469868A (da) |
| EP (1) | EP0095289B1 (da) |
| JP (1) | JPS58210087A (da) |
| KR (1) | KR870000931B1 (da) |
| AR (1) | AR240941A1 (da) |
| AT (1) | ATE24510T1 (da) |
| AU (1) | AU553708B2 (da) |
| CA (1) | CA1210393A (da) |
| DE (1) | DE3368635D1 (da) |
| DK (1) | DK161968C (da) |
| ES (4) | ES8407051A1 (da) |
| FI (1) | FI74012C (da) |
| GR (1) | GR79262B (da) |
| HK (1) | HK102989A (da) |
| HU (1) | HU187913B (da) |
| IE (1) | IE55111B1 (da) |
| IL (1) | IL68360A0 (da) |
| NO (1) | NO160444C (da) |
| NZ (1) | NZ204321A (da) |
| PH (1) | PH18454A (da) |
| PT (1) | PT76745B (da) |
| ZA (1) | ZA832637B (da) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1988000192A1 (en) * | 1986-06-26 | 1988-01-14 | Warner-Lambert Company | 5-SUBSTITUTED PYRAZOLO[4,3-d]PYRIMIDIN-7-ONES |
| AU2005323311A1 (en) * | 2004-11-23 | 2006-07-13 | Venkateswara Rao Batchu | Novel bicyclic heterocyclic compounds, process for their preparation and compositions containing them |
| WO2006133261A2 (en) | 2005-06-06 | 2006-12-14 | Intra-Cellular Therapies, Inc. | Organic compounds |
| EP2089034A4 (en) | 2006-12-05 | 2010-07-28 | Intra Cellular Therapies Inc | NEW USES |
| EA201170769A1 (ru) | 2008-12-06 | 2012-02-28 | Интра-Селлулар Терапиз, Инк. | Органические соединения |
| WO2010132127A1 (en) | 2009-05-13 | 2010-11-18 | Intra-Cellular Therapies, Inc. | Organic compounds |
| EP2576551A4 (en) | 2010-05-31 | 2014-04-16 | Intra Cellular Therapies Inc | ORGANIC CONNECTIONS |
| TW201206937A (en) | 2010-05-31 | 2012-02-16 | Intra Cellular Therapies Inc | Organic compounds |
| CN103492389B (zh) * | 2011-04-21 | 2016-09-14 | 原真股份有限公司 | 用作激酶抑制剂的吡唑并[4,3-d]嘧啶 |
| US9637491B2 (en) | 2012-10-19 | 2017-05-02 | Origenis Gmbh | Pyrazolo[4,3-D]pyrimidines as kinase inhibitors |
| EP2956141A4 (en) | 2013-02-17 | 2016-10-26 | Intra Cellular Therapies Inc | NEW USES |
| EP3479825B1 (en) | 2013-03-15 | 2021-02-17 | Intra-Cellular Therapies, Inc. | Pde1 inhibitors for use in the treatment and/or prevention of cns or pns diseases or disorders |
| AU2014234990B2 (en) | 2013-03-15 | 2017-11-16 | Intra-Cellular Therapies, Inc. | Organic compounds |
| WO2015196186A1 (en) | 2014-06-20 | 2015-12-23 | Intra-Cellular Therapies, Inc. | Organic compounds |
| US10131671B2 (en) | 2014-08-07 | 2018-11-20 | Intra-Cellular Therapies, Inc. | Organic compounds |
| US10285992B2 (en) | 2014-08-07 | 2019-05-14 | Intra-Cellular Therapies, Inc. | Combinations of PDE1 inhibitors and NEP inhibitors and associated methods |
| RU2711442C2 (ru) | 2014-09-17 | 2020-01-17 | Интра-Селлулар Терапиз, Инк. | Соединения и способы |
| US10682354B2 (en) | 2016-03-28 | 2020-06-16 | Intra-Cellular Therapies, Inc. | Compositions and methods |
| US11291666B2 (en) | 2016-09-12 | 2022-04-05 | Intra-Cellular Therapies, Inc. | Uses |
| EP3746081A4 (en) | 2018-01-31 | 2021-10-27 | Intra-Cellular Therapies, Inc. | Novel uses |
| US12410175B2 (en) | 2019-09-03 | 2025-09-09 | Intra-Cellular Therapies, Inc. | Compounds |
| US12364695B2 (en) | 2020-06-02 | 2025-07-22 | Intra-Cellular Therapies, Inc. | Methods of treating inflammatory disease |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH422807A (de) * | 1963-08-16 | 1966-10-31 | Wander Ag Dr A | Verfahren zur Herstellung von Imidazo- und Pyrimidochinazolinen |
| US3313815A (en) * | 1964-05-04 | 1967-04-11 | Sterling Drug Inc | 8-chloropyrazolo-[1, 5-c]quinazoline derivatives and methods of preparing same |
| US3309369A (en) * | 1966-04-11 | 1967-03-14 | Wander Ag Dr A | Imidazo- and pyrimido-quinazolines |
| US3594379A (en) * | 1968-09-16 | 1971-07-20 | Sandoz Ag | 2,3-dihydroimidazo(1,2-c)quinazolines |
| DE2058501A1 (de) * | 1970-11-27 | 1972-05-31 | Bayer Ag | Verfahren zur Herstellung von neuen N-verbrueckten bicyclischen Heteroaromaten |
| GB1347493A (en) * | 1971-02-11 | 1974-02-27 | Aspro Nicholas Ltd | Benzazine derivatives |
| US3984556A (en) * | 1973-01-19 | 1976-10-05 | Sandoz, Inc. | Alkyl-substituted-tricyclic quinazolinones for lowering blood pressure |
| JPS516993A (en) * | 1974-07-05 | 1976-01-20 | Dainippon Pharmaceutical Co | Adeninjudotaino seiho |
| JPS5398997A (en) * | 1977-02-09 | 1978-08-29 | Sumitomo Chem Co Ltd | Fused pyridine derivertives and process for their preparation |
| US4250181A (en) * | 1977-10-31 | 1981-02-10 | The Upjohn Company | Methods of treating psychosis |
| US4247553A (en) * | 1977-10-31 | 1981-01-27 | The Upjohn Company | Methods of treating psychosis |
| US4206123A (en) * | 1977-10-31 | 1980-06-03 | Mccall John M | Isothiochroman |
| US4192803A (en) * | 1978-09-15 | 1980-03-11 | American Cyanamid Company | 5H-Pyrrolo[2,1-c][1,4]benzodiazepine derivatives |
| BG33279A3 (en) * | 1978-11-01 | 1983-01-14 | The Wellcome Foundation Limited | Method for making of carbazole compounds |
| CH643263A5 (de) * | 1979-05-11 | 1984-05-30 | Sandoz Ag | Benzodiazepine, ihre herstellung und verwendung. |
| HU178523B (en) * | 1979-05-18 | 1982-05-28 | Egyt Gyogyszervegyeszeti Gyar | Process for preparing new pyrazolo-quinazoline derivatives |
| US4230707A (en) * | 1979-08-27 | 1980-10-28 | Warner-Lambert Company | Oxo-pyrido[1,2-a]thienopyrimidine compounds and methods for their production |
| US4358456A (en) * | 1980-05-03 | 1982-11-09 | John Wyeth & Brother Limited | Antipsychotic piperidinomethyl-indole derivatives |
| US4396770A (en) * | 1982-04-09 | 1983-08-02 | Hoechst-Roussel Pharmaceuticals Inc. | 1-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-4-hydroxy-4-phenylpiperidines |
| US4352811A (en) * | 1981-11-12 | 1982-10-05 | Hoechst-Roussel Pharmaceuticals Inc. | 3-(1-Substituted-4-piperidyl)-1,2-benzisoxazoles |
| US4374245A (en) * | 1982-04-09 | 1983-02-15 | Hoechst-Roussel Pharmaceuticals Inc. | 8-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one |
| US4390544A (en) * | 1982-04-09 | 1983-06-28 | Hoechst-Roussel Pharmaceuticals Inc. | {1-[3-(6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-4-(2-oxo-1-benzimidazolinyl}p |
| US4415581A (en) * | 1982-04-09 | 1983-11-15 | Hoechst-Roussel Pharmaceuticals Inc. | 1-[3-6-Fluoro-1,2-benzisoxazol-3-yl)propyl]-4-hydroxy-4-phenylpiperidines to treat psychoses |
| US4409230A (en) * | 1982-04-09 | 1983-10-11 | Hoechst-Roussel Pharmaceuticals Inc. | Pharmaceutical compositions and methods employing 8-[3-(6-fluoro-1,2-benzisoxazol-3-yl)propyl]-1-phenyl-1,3,8-triazaspiro-[4.]decan-4-one and derivatives thereof |
| US5059699A (en) * | 1990-08-28 | 1991-10-22 | Virginia Tech Intellectual Properties, Inc. | Water soluble derivatives of taxol |
-
1982
- 1982-05-24 US US06/381,484 patent/US4469868A/en not_active Expired - Fee Related
-
1983
- 1983-04-11 IE IE822/83A patent/IE55111B1/en unknown
- 1983-04-12 IL IL68360A patent/IL68360A0/xx unknown
- 1983-04-12 AU AU13427/83A patent/AU553708B2/en not_active Ceased
- 1983-04-14 ZA ZA832637A patent/ZA832637B/xx unknown
- 1983-04-19 CA CA000426194A patent/CA1210393A/en not_active Expired
- 1983-05-13 DE DE8383302715T patent/DE3368635D1/de not_active Expired
- 1983-05-13 AT AT83302715T patent/ATE24510T1/de not_active IP Right Cessation
- 1983-05-13 EP EP83302715A patent/EP0095289B1/en not_active Expired
- 1983-05-18 PH PH28929A patent/PH18454A/en unknown
- 1983-05-18 FI FI831742A patent/FI74012C/fi not_active IP Right Cessation
- 1983-05-20 DK DK227183A patent/DK161968C/da not_active IP Right Cessation
- 1983-05-20 NO NO831792A patent/NO160444C/no unknown
- 1983-05-23 HU HU831811A patent/HU187913B/hu not_active IP Right Cessation
- 1983-05-23 ES ES522617A patent/ES8407051A1/es not_active Expired
- 1983-05-23 GR GR71429A patent/GR79262B/el unknown
- 1983-05-23 NZ NZ204321A patent/NZ204321A/en unknown
- 1983-05-23 KR KR1019830002255A patent/KR870000931B1/ko not_active Expired
- 1983-05-23 PT PT76745A patent/PT76745B/pt unknown
- 1983-05-24 JP JP58090133A patent/JPS58210087A/ja active Granted
-
1984
- 1984-02-01 ES ES529371A patent/ES529371A0/es active Granted
- 1984-02-01 ES ES529372A patent/ES8506019A1/es not_active Expired
- 1984-02-01 ES ES529373A patent/ES8506004A1/es not_active Expired
-
1985
- 1985-06-26 AR AR300815A patent/AR240941A1/es active
-
1989
- 1989-12-28 HK HK1029/89A patent/HK102989A/xx unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK227183D0 (da) | Fremgangsmade til fremstilling af imidazo (1,2-c)-pyrazolo(3,4-e) pyrimidiner med den almene formel i | |
| DK120783D0 (da) | Fremgangsmade til fremstilling af substituerede 1h-pyrazolo(1,5-a)pyrimidiner | |
| ES531285A0 (es) | Procedimiento de preparacion de derivados de 1,3-dihidro-6-metil-7-hidroxi-furo-(3,4-c)-piridina | |
| NO874302L (no) | Fremgangsmaate for fremstilling av 4,5-dihydro- og 4,5,6,7-tetrahydro- pyrazolo(1,5-a)pyrimidiner. | |
| FI834665A0 (fi) | Imidazo(1,5-a)pyridin-derivat | |
| AR229519A1 (es) | Procedimiento de preparacion de derivados de 2,3-dihidro-9-fenil-1h-pirazolo(1,2-a)-indazolio | |
| DK390583D0 (da) | Fremgangsmade til fremstilling af imidazo(1,2-a)pyrimidiner | |
| PT71197A (en) | Process for the preparation of substituted pyrido/1,2-a/pyrimidines | |
| PT75240A (en) | Process for the preparation of substituted thiazolo <3,2-a>pyrimidines | |
| FI834664A0 (fi) | Substituerade imidazo(1,5-a)pyridiner | |
| DK44383D0 (da) | Fremgangsmade til fremstilling af substituerede 1,3,4-thiadiazolo(3,2-a)pyrimidiner | |
| DK584484D0 (da) | Kemisk fremgangsmaade til fremstilling af antibiotikum l 17054 | |
| DK96379A (da) | Fremgangsmaade til fremstilling af disubstituerede 2,3-dihydroimidazo (1,2-c)-pyrimidiner | |
| DK288079A (da) | Fremgangsmaade til fremstilling af imidazolylethoxyderivater af pyrazolo (3,4-b) pyridin-5-methanoler | |
| DK367388D0 (da) | Til fremstilling af hoejredrejende 3-(3-pyridyl)-1h,3h-pyrrolo(1,2-c)thiazol-7-carboxylsyre | |
| DK133883D0 (da) | Fremgangsmade til fremstilling af substituerede ethenylderivater af 1h-pyrazolo(1,5-a)pyrimidin | |
| DK108283A (da) | Fremgangsmaade til fremstilling af pentacycliske forbindelser | |
| DK154971C (da) | Fremgangsmaade til fremstilling af phenylpyridazinforbindelser | |
| PT75244A (de) | Verfahren zur herstellung von 5,11-dihydro-6h-pyrido <2,3-b>-<1,4> benzodiazepin-6-onen | |
| DK192683D0 (da) | Fremgangsmade til fremstilling af kondenserede cycloaliphatiske derivater af substituerede (1,2-a)pyrimidiner | |
| DK55783A (da) | Fremgangsmaade til fremstilling af 1-substitueret-6-n-propyl-8-methylimidazo(1,5-d)-as-triazin-4(3h)-oner | |
| AR227783A1 (es) | Procedimiento para preparar derivados de 4,5,7,8-tetrahidro-4,4,8,8-tetrametil-1-h-tiepin(4,5-d)imidazol | |
| ATA416882A (de) | Verfahren zur herstellung von neuen spiro-derivaten des pyrazolo (1,5-d) (1,2,4) triazin-ring-systems | |
| IT8048792A0 (it) | Composti di imidazo (1,5-d)as-triazin-4(3h)-oni e -tioni sostituiti e procedimento per laloro preparazione | |
| GR860095B (en) | Method for the preparation of novel heterocyclic compounds |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PBP | Patent lapsed |