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DK218787D0 - Benzamidderivater - Google Patents

Benzamidderivater

Info

Publication number
DK218787D0
DK218787D0 DK218787A DK218787A DK218787D0 DK 218787 D0 DK218787 D0 DK 218787D0 DK 218787 A DK218787 A DK 218787A DK 218787 A DK218787 A DK 218787A DK 218787 D0 DK218787 D0 DK 218787D0
Authority
DK
Denmark
Prior art keywords
benzamide
Prior art date
Application number
DK218787A
Other languages
English (en)
Other versions
DK218787A (da
DK175281B1 (da
Inventor
Tatsuya Kon
Shiro Kato
Toshiya Morie
Kazunori Ohno
Katsuhiko Hino
Tadahiko Karasawa
Naoyuki Yoshida
Original Assignee
Dainippon Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dainippon Pharmaceutical Co filed Critical Dainippon Pharmaceutical Co
Publication of DK218787D0 publication Critical patent/DK218787D0/da
Publication of DK218787A publication Critical patent/DK218787A/da
Application granted granted Critical
Publication of DK175281B1 publication Critical patent/DK175281B1/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D265/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/281,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/301,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D267/00Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D267/02Seven-membered rings
    • C07D267/08Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D267/10Seven-membered rings having the hetero atoms in positions 1 and 4 not condensed with other rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK198702187A 1986-04-30 1987-04-29 Benzamidderivater, en fremgangsmåde til deres fremstilling samt farmaceutisk præparat indeholdende dem DK175281B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP10155286 1986-04-30
JP10155286 1986-04-30
JP31509086 1986-12-31
JP31509086 1986-12-31

Publications (3)

Publication Number Publication Date
DK218787D0 true DK218787D0 (da) 1987-04-29
DK218787A DK218787A (da) 1987-10-31
DK175281B1 DK175281B1 (da) 2004-08-09

Family

ID=26442419

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198702187A DK175281B1 (da) 1986-04-30 1987-04-29 Benzamidderivater, en fremgangsmåde til deres fremstilling samt farmaceutisk præparat indeholdende dem

Country Status (18)

Country Link
US (1) US4870074A (da)
EP (1) EP0243959B1 (da)
KR (1) KR870010030A (da)
AR (1) AR242953A1 (da)
AU (1) AU592177B2 (da)
CA (1) CA1291135C (da)
CZ (1) CZ284687B6 (da)
DE (1) DE3781195T2 (da)
DK (1) DK175281B1 (da)
ES (1) ES2043617T3 (da)
FI (1) FI87776C (da)
GR (1) GR3005934T3 (da)
HK (1) HK18194A (da)
HU (1) HU198193B (da)
NZ (1) NZ220120A (da)
PH (1) PH24049A (da)
SK (1) SK279058B6 (da)
SU (1) SU1597101A3 (da)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2640139A1 (fr) * 1988-12-14 1990-06-15 Delagrange Laboratoires Application de benzamides substitues comme gastromoteurs
US5395832A (en) * 1991-02-15 1995-03-07 Hokuriku Seiyaku Co., Ltd. Benzamide derivatives
TW243449B (da) * 1991-02-15 1995-03-21 Hokuriku Pharmaceutical
WO1995026953A1 (en) * 1994-03-30 1995-10-12 Yoshitomi Pharmaceutical Industries, Ltd. Benzoic acid compound and use thereof as medicine
US5864039A (en) * 1994-03-30 1999-01-26 Yoshitomi Pharmaceutical Industries, Ltd. Benzoic acid compounds and use thereof as medicaments
KR100446099B1 (ko) * 1995-05-23 2004-11-10 얀센 파마슈티카 엔.브이. (2-모르폴리닐메틸)벤즈아미드유도체
JP2001064177A (ja) * 1999-08-16 2001-03-13 Schering Ag ベンズアミド誘導体を有効成分とする製剤
NZ525056A (en) 2000-09-29 2004-11-26 Glaxo Group Ltd Morpholin-acetamide derivatives for the treatment of inflammatory diseases
AU2002224885A1 (en) * 2000-11-28 2002-06-11 Smithkline Beecham Plc Morpholine derivatives as antagonists of orexin receptors
JP4829417B2 (ja) * 2001-03-26 2011-12-07 明夫 乾 インスリン抵抗性改善薬
MXPA04003002A (es) * 2001-10-08 2004-07-15 Sun Pharmaceutical Ind Ltd Un sistema de administracion espacial de farmacos para agentes antiespasmodicos.
GB0207449D0 (en) * 2002-03-28 2002-05-08 Glaxo Group Ltd Novel compounds
GB0208158D0 (en) * 2002-03-28 2002-05-22 Glaxo Group Ltd Novel compounds
GB0207447D0 (en) * 2002-03-28 2002-05-08 Glaxo Group Ltd Novel compounds
HUP0201980A3 (en) * 2002-06-13 2008-06-30 Richter Gedeon Nyrt Process for preparing a benzamide derivative and intermediates thereof
JP4740740B2 (ja) * 2003-12-09 2011-08-03 大日本住友製薬株式会社 薬物含有粒子および該粒子を含む固形製剤
US8138204B2 (en) * 2004-01-07 2012-03-20 Aryx Therapeutics, Inc. Stereoisomeric compounds and methods for the treatment of gastrointestinal and central nervous system disorders
JP5200288B2 (ja) * 2004-01-07 2013-06-05 アルメテオン、インコーポレイテッド 胃腸疾患および中枢神経系疾患の治療のための立体異性体化合物と方法
US8524736B2 (en) 2004-01-07 2013-09-03 Armetheon, Inc. Stereoisomeric compounds and methods for the treatment of gastrointestinal and central nervous system disorders
IN2014CN03493A (da) * 2004-09-08 2015-07-03 Mitsubishi Tanabe Pharma Corp
WO2007002157A2 (en) * 2005-06-23 2007-01-04 Array Biopharma Inc. Process for preparing benzimidazole compounds
KR101351454B1 (ko) * 2005-08-31 2014-01-14 아메데온, 인코포레이티드 위장 및 중추 신경계 장애의 치료에 유용한 입체이성질체 화합물의 합성 방법 및 중간 생성물
WO2007075749A2 (en) * 2005-12-20 2007-07-05 Merck & Co., Inc. Niacin receptor agonists, compositions containing such compounds and methods of treatment
KR100750593B1 (ko) * 2006-03-16 2007-08-20 동우신테크 주식회사 치환된 벤즈아미드 유도체의 제조방법
US20080085915A1 (en) * 2006-06-23 2008-04-10 Cyrus Becker Compounds and methods for the treatment of gastrointestinal and central nervous system disorders
CA2686545C (en) 2007-04-19 2010-11-02 Concert Pharmaceuticals Inc. Deuterated morpholinyl compounds
CN101402633A (zh) * 2007-09-11 2009-04-08 上海恒瑞医药有限公司 苯甲酰胺类衍生物、其制备方法及其在医药上的用途
KR101612137B1 (ko) 2008-02-13 2016-04-12 다이닛본 스미토모 세이야꾸 가부시끼가이샤 구강 내 붕괴정
TWI423967B (zh) * 2008-02-21 2014-01-21 Dainippon Sumitomo Pharma Co 醯胺衍生物及含有其之醫藥組合物
KR20120046766A (ko) 2009-08-11 2012-05-10 다이닛본 스미토모 세이야꾸 가부시끼가이샤 2종 이상의 입자들을 함유하는 구강 속붕해성 정제
WO2011107903A1 (en) 2010-03-04 2011-09-09 Ranbaxy Laboratories Limited Highly pure mosapride citrate dihydrate and processes for its preparation
ES2587304T3 (es) 2011-02-25 2016-10-21 Yuhan Corporation Derivados de diaminopirimidina y procedimientos para la preparación de los mismos
KR101657616B1 (ko) 2013-05-24 2016-09-19 주식회사유한양행 피리미딘 고리를 포함하는 바이사이클릭 유도체 및 그의 제조방법
TWI794171B (zh) 2016-05-11 2023-03-01 美商滬亞生物國際有限公司 Hdac抑制劑與pd-l1抑制劑之組合治療
TWI808055B (zh) 2016-05-11 2023-07-11 美商滬亞生物國際有限公司 Hdac 抑制劑與 pd-1 抑制劑之組合治療
CN111349052B (zh) * 2020-04-07 2021-02-12 福建海西新药创制有限公司 一种枸橼酸莫沙必利的合成方法
CN114560822B (zh) * 2020-11-27 2024-05-28 鲁南制药集团股份有限公司 一种莫沙必利的二羧酸晶体
CN114591260B (zh) * 2020-12-05 2025-07-11 鲁南制药集团股份有限公司 一种莫沙必利有机酸盐
CN119241463A (zh) * 2024-10-22 2025-01-03 吉林修正药业新药开发有限公司 一种枸橼酸莫沙必利杂质化合物及其制备方法
CN119241464A (zh) * 2024-10-22 2025-01-03 吉林修正药业新药开发有限公司 一种枸橼酸莫沙必利杂质化合物及其制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH451142A (de) * 1965-01-19 1968-05-15 Sandoz Ag Verfahren zur Herstellung neuer basisch substituierter Benzoesäureamide
US4029786A (en) * 1972-08-11 1977-06-14 Imperial Chemical Industries Limited Morpholine derivatives for treating depression
US4323503A (en) * 1976-08-04 1982-04-06 Societe D'etudes Scientifiques Et Industrielles De L'ile-De-France Substituted 2,3-alkylene di (oxy) benzamides and derivatives
US4210754A (en) * 1977-02-01 1980-07-01 Hoffmann-La Roche Inc. Morpholino containing benzamides
US4692445A (en) * 1983-04-29 1987-09-08 Rorer Pharmaceutical Corporation Bicyclic benzenoid aminoalkylene ethers and thioethers, pharmaceutical compositions and use
FR2575158B1 (fr) * 1984-12-20 1987-10-02 Pf Medicament Arylalcoyloxymethyl-2 morpholines, leur preparation et leur application en tant que medicaments utiles dans le traitement des troubles du systeme nerveux central
JPH0390274A (ja) * 1989-08-28 1991-04-16 Furukawa Alum Co Ltd Al又はAl合金の気相ろう付法

Also Published As

Publication number Publication date
FI87776C (fi) 1993-02-25
FI87776B (fi) 1992-11-13
AU592177B2 (en) 1990-01-04
AU7227587A (en) 1987-11-05
FI871828A0 (fi) 1987-04-27
HK18194A (en) 1994-03-11
SK289787A3 (en) 1998-06-03
DK218787A (da) 1987-10-31
EP0243959B1 (en) 1992-08-19
SU1597101A3 (ru) 1990-09-30
SK279058B6 (sk) 1998-06-03
US4870074A (en) 1989-09-26
EP0243959A1 (en) 1987-11-04
AR242953A1 (es) 1993-06-30
CZ289787A3 (cs) 1998-11-11
CA1291135C (en) 1991-10-22
DE3781195D1 (de) 1992-09-24
GR3005934T3 (da) 1993-06-07
HU198193B (en) 1989-08-28
HUT45514A (en) 1988-07-28
ES2043617T3 (es) 1994-01-01
DK175281B1 (da) 2004-08-09
FI871828A7 (fi) 1987-10-31
PH24049A (en) 1990-03-05
CZ284687B6 (cs) 1999-02-17
NZ220120A (en) 1989-06-28
KR870010030A (ko) 1987-11-30
DE3781195T2 (de) 1993-02-18

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Legal Events

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PUP Patent expired