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DK2035549T3 - Abcb5-positive mesenkymale stamceller som immunmodulatorer - Google Patents

Abcb5-positive mesenkymale stamceller som immunmodulatorer

Info

Publication number
DK2035549T3
DK2035549T3 DK07795647.2T DK07795647T DK2035549T3 DK 2035549 T3 DK2035549 T3 DK 2035549T3 DK 07795647 T DK07795647 T DK 07795647T DK 2035549 T3 DK2035549 T3 DK 2035549T3
Authority
DK
Denmark
Prior art keywords
mesenkymal
abcb5
positive
stem cells
immune modulators
Prior art date
Application number
DK07795647.2T
Other languages
English (en)
Inventor
Markus H Frank
Original Assignee
Childrens Medical Center
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Childrens Medical Center filed Critical Childrens Medical Center
Application granted granted Critical
Publication of DK2035549T3 publication Critical patent/DK2035549T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0625—Epidermal cells, skin cells; Cells of the oral mucosa
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0668—Mesenchymal stem cells from other natural sources

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Neurology (AREA)
  • Vascular Medicine (AREA)
  • Neurosurgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK07795647.2T 2006-05-31 2007-05-31 Abcb5-positive mesenkymale stamceller som immunmodulatorer DK2035549T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80940706P 2006-05-31 2006-05-31
PCT/US2007/013022 WO2007143139A1 (en) 2006-05-31 2007-05-31 Abcb5 positive mesenchymal stem cells as immunomodulators

Publications (1)

Publication Number Publication Date
DK2035549T3 true DK2035549T3 (da) 2014-10-13

Family

ID=38594403

Family Applications (2)

Application Number Title Priority Date Filing Date
DK14168199.9T DK2772535T3 (da) 2006-05-31 2007-05-31 ABC5-positive mesenkymale stamceller som immunmodulatorer
DK07795647.2T DK2035549T3 (da) 2006-05-31 2007-05-31 Abcb5-positive mesenkymale stamceller som immunmodulatorer

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK14168199.9T DK2772535T3 (da) 2006-05-31 2007-05-31 ABC5-positive mesenkymale stamceller som immunmodulatorer

Country Status (12)

Country Link
US (4) US8455245B2 (da)
EP (2) EP2772535B1 (da)
AU (1) AU2007254894B9 (da)
CA (1) CA2685492C (da)
DK (2) DK2772535T3 (da)
ES (2) ES2918323T3 (da)
HU (1) HUE059011T2 (da)
LT (1) LT2772535T (da)
PL (2) PL2035549T3 (da)
PT (2) PT2772535T (da)
SI (2) SI2772535T1 (da)
WO (1) WO2007143139A1 (da)

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AU2007254894B9 (en) 2006-05-31 2014-11-13 Children's Medical Center Corporation ABCB5 positive mesenchymal stem cells as immunomodulators
CA2718573C (en) 2007-04-12 2020-07-14 The Brigham And Women's Hospital, Inc. Targeting abcb5 for cancer therapy
US11542328B2 (en) 2008-11-14 2023-01-03 The Brigham And Women's Hospital, Inc. Therapeutic and diagnostic methods relating to cancer stem cells
WO2010056332A1 (en) 2008-11-14 2010-05-20 The Brigham And Women's Hospital, Inc. Therapeutic and diagnostic methods relating to cancer stem cells
DK2964238T3 (da) 2013-02-19 2021-03-22 Childrens Medical Center Abcb5(+) stem cells for treating ocular disease
CA2911232C (en) * 2013-05-10 2021-11-09 Children's Medical Center Corporation Wound healing and tissue engineering
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EP3946389A4 (en) * 2019-03-28 2023-05-10 Children's Medical Center Corporation HIGH FUNCTIONAL ENGINEERED ABCB5+ MESENCHYMAL STEM CELLS
AU2020263509A1 (en) * 2019-04-24 2021-11-11 Children's Medical Center Corporation ABCB5+ stem cell therapeutics for liver disease
US20230148432A1 (en) * 2020-03-30 2023-05-11 Children's Medical Center Corporation Use of stem cells for treatment of excessive inflammation
AU2022273715A1 (en) * 2021-05-13 2023-11-30 Primegen Us, Inc. Methods and compositions for treating liver disease
US20230256065A1 (en) * 2022-02-16 2023-08-17 Elena RUSYN Autologous stem cell vaccine and methods
CN115260098B (zh) * 2022-06-09 2024-06-04 澳门科技大学 Abcb5抑制剂在制备多耐药性类风湿性关节炎治疗药物中的应用

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US11542328B2 (en) 2008-11-14 2023-01-03 The Brigham And Women's Hospital, Inc. Therapeutic and diagnostic methods relating to cancer stem cells
DK2964238T3 (da) 2013-02-19 2021-03-22 Childrens Medical Center Abcb5(+) stem cells for treating ocular disease
CA2911232C (en) 2013-05-10 2021-11-09 Children's Medical Center Corporation Wound healing and tissue engineering
KR20210005118A (ko) 2018-04-25 2021-01-13 칠드런'즈 메디컬 센터 코포레이션 Abcb5 리간드 및 기질
EP3946389A4 (en) 2019-03-28 2023-05-10 Children's Medical Center Corporation HIGH FUNCTIONAL ENGINEERED ABCB5+ MESENCHYMAL STEM CELLS

Also Published As

Publication number Publication date
ES2918323T3 (es) 2022-07-15
CA2685492A1 (en) 2007-12-13
US11624054B2 (en) 2023-04-11
SI2772535T1 (sl) 2022-08-31
DK2772535T3 (da) 2022-07-04
US20230313136A1 (en) 2023-10-05
PL2772535T3 (pl) 2022-09-05
CA2685492C (en) 2018-01-16
PT2772535T (pt) 2022-07-04
US20080003206A1 (en) 2008-01-03
LT2772535T (lt) 2022-08-25
US20130315880A1 (en) 2013-11-28
AU2007254894B9 (en) 2014-11-13
AU2007254894B2 (en) 2014-10-23
US8455245B2 (en) 2013-06-04
HUE059011T2 (hu) 2022-09-28
US10017738B2 (en) 2018-07-10
HK1201295A1 (en) 2015-08-28
SI2035549T1 (sl) 2015-03-31
HK1129703A1 (en) 2009-12-04
EP2035549A1 (en) 2009-03-18
WO2007143139A1 (en) 2007-12-13
ES2511791T3 (es) 2014-10-23
EP2772535B1 (en) 2022-04-06
PT2035549E (pt) 2014-10-06
AU2007254894A1 (en) 2007-12-13
PL2035549T3 (pl) 2014-12-31
US20180320131A1 (en) 2018-11-08
EP2772535A1 (en) 2014-09-03
EP2035549B1 (en) 2014-07-09

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