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DK189584D0 - (5alfa)-20-spirox-1-en-3-oner samt deres fremstilling og anvendelse - Google Patents

(5alfa)-20-spirox-1-en-3-oner samt deres fremstilling og anvendelse

Info

Publication number
DK189584D0
DK189584D0 DK1895/84A DK189584A DK189584D0 DK 189584 D0 DK189584 D0 DK 189584D0 DK 1895/84 A DK1895/84 A DK 1895/84A DK 189584 A DK189584 A DK 189584A DK 189584 D0 DK189584 D0 DK 189584D0
Authority
DK
Denmark
Prior art keywords
5alfa
spirox
oner
preparation
Prior art date
Application number
DK1895/84A
Other languages
English (en)
Other versions
DK189584A (da
Inventor
Juergen Grob
Jaroslav Kalvoda
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of DK189584D0 publication Critical patent/DK189584D0/da
Publication of DK189584A publication Critical patent/DK189584A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005Oxygen-containing hetero ring
    • C07J71/001Oxiranes
    • C07J71/0015Oxiranes at position 9(11)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A61K31/585Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J21/00Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/001Lactones
    • C07J21/003Lactones at position 17

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
DK189584A 1983-04-13 1984-04-12 (5alfa)-20-spirox-1-en-3-oner samt deres fremstilling og anvendelse DK189584A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH197983 1983-04-13
CH197983 1983-04-13

Publications (2)

Publication Number Publication Date
DK189584D0 true DK189584D0 (da) 1984-04-12
DK189584A DK189584A (da) 1984-10-14

Family

ID=4223075

Family Applications (1)

Application Number Title Priority Date Filing Date
DK189584A DK189584A (da) 1983-04-13 1984-04-12 (5alfa)-20-spirox-1-en-3-oner samt deres fremstilling og anvendelse

Country Status (6)

Country Link
US (1) US4552871A (da)
EP (1) EP0122882A1 (da)
JP (1) JPS59205400A (da)
AU (1) AU2685284A (da)
DK (1) DK189584A (da)
ES (1) ES531516A0 (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999061055A1 (en) 1998-05-22 1999-12-02 The Board Of Trustees Of The Leland Stanford Junior University Bifunctional molecules and therapies based thereon
CA2469616A1 (en) 2001-12-12 2003-06-19 James W. Aiken Method of treating ophthalmic disorders with epoxy-steroidal aldosterone receptor antagonists
CA2789097C (en) 2005-04-28 2017-02-21 Proteus Digital Health, Inc. Pharma-informatics system
WO2007035716A2 (en) 2005-09-16 2007-03-29 Raptor Pharmaceutical Inc. Compositions comprising receptor-associated protein (rap) variants specific for cr-containing proteins and uses thereof
NZ616673A (en) 2009-02-20 2014-08-29 To Bbb Holding B V Glutathione-based drug delivery system
ES2942923T3 (es) 2009-05-06 2023-06-07 Laboratory Skin Care Inc Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3095412A (en) * 1961-12-19 1963-06-25 Searle & Co 9alpha, 11alpha-epoxy and 11beta-chloro-9alpha-hydroxy 17alpha-(2-carboxyethyl)-17beta-hydroxyandrost-4-en-3-one gamma-lactones and delta1 and delta6 analogs
GB1368731A (en) * 1972-01-24 1974-10-02 Searle & Co 9alpha 11alpha-epoxy spirolactones and corresponding spirolactols and lactol ethers
CH631462A5 (de) * 1976-03-05 1982-08-13 Schering Ag Verfahren zur herstellung von neuen steroiden der androstan- oder oestranreihe.
US4079054A (en) * 1976-12-22 1978-03-14 Schering Corporation 7α-Halogeno-3-oxo-1,4-pregnadiene-21,17β-carbolactones and related compounds

Also Published As

Publication number Publication date
EP0122882A1 (de) 1984-10-24
US4552871A (en) 1985-11-12
JPS59205400A (ja) 1984-11-20
ES8602845A1 (es) 1985-12-01
AU2685284A (en) 1984-10-18
ES531516A0 (es) 1985-12-01
DK189584A (da) 1984-10-14

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment
AHS Application shelved for other reasons than non-payment