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DK1891446T3 - Fremgangsmåde til identifikation af nye enzymvekselvirkende forbindelser - Google Patents

Fremgangsmåde til identifikation af nye enzymvekselvirkende forbindelser

Info

Publication number
DK1891446T3
DK1891446T3 DK06763568.0T DK06763568T DK1891446T3 DK 1891446 T3 DK1891446 T3 DK 1891446T3 DK 06763568 T DK06763568 T DK 06763568T DK 1891446 T3 DK1891446 T3 DK 1891446T3
Authority
DK
Denmark
Prior art keywords
identifying novel
novel enzyme
interacting compounds
interacting
compounds
Prior art date
Application number
DK06763568.0T
Other languages
English (en)
Inventor
Carsten Hopf
Gerard Drewes
Bernhard Kuester
Ulrich Kruse
Dirk Eberhard
Marcus Bantscheff
Valerie Reader
David Middlemiss
Manfred Raida
Original Assignee
Cellzome Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cellzome Gmbh filed Critical Cellzome Gmbh
Priority claimed from PCT/EP2006/062984 external-priority patent/WO2006134056A1/en
Application granted granted Critical
Publication of DK1891446T3 publication Critical patent/DK1891446T3/da

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848Methods of protein analysis involving mass spectrometry
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • C12Q1/485Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving kinase
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Hematology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Food Science & Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK06763568.0T 2005-06-14 2006-06-07 Fremgangsmåde til identifikation af nye enzymvekselvirkende forbindelser DK1891446T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP05012722A EP1734367A1 (en) 2005-06-14 2005-06-14 Process for the identification of novel enzyme interacting compounds
US71139905P 2005-08-25 2005-08-25
US78217006P 2006-03-14 2006-03-14
PCT/EP2006/062984 WO2006134056A1 (en) 2005-06-14 2006-06-07 Process for the identification of novel enzyme interacting compounds

Publications (1)

Publication Number Publication Date
DK1891446T3 true DK1891446T3 (da) 2013-06-17

Family

ID=34937423

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06763568.0T DK1891446T3 (da) 2005-06-14 2006-06-07 Fremgangsmåde til identifikation af nye enzymvekselvirkende forbindelser

Country Status (8)

Country Link
EP (3) EP1734367A1 (da)
JP (1) JP4932835B2 (da)
CN (1) CN101223447A (da)
DE (1) DE6763568T1 (da)
DK (1) DK1891446T3 (da)
ES (1) ES2412380T3 (da)
PT (1) PT1891446E (da)
SI (1) SI1891446T1 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2375541T3 (es) * 2008-02-04 2012-03-01 Cellzome Ag Obtención del perfil de selectividad de moléculas de interación con pi3k contra dianas múltiples.
ATE547707T1 (de) * 2008-05-16 2012-03-15 Cellzome Ag Verfahren zur identifizierung von mit parp wechselwirkenden molekülen und zur aufreinigung von parp-proteinen
EP2124060A1 (en) * 2008-05-23 2009-11-25 ETH Zurich Method for high throughput peptide/protein assay generation and assays generated therewith
WO2010070394A1 (en) * 2008-12-17 2010-06-24 Universite Pierre Et Marie Curie-Paris Vi Modulators of the cx3cr1 receptor and therapeutic uses thereof
CA2785534C (en) * 2009-12-22 2019-07-30 Expression Pathology, Inc. Epidermal growth factor receptor (egfr) protein srm/mrm assay
CN109690316A (zh) * 2016-05-31 2019-04-26 王帅 测定细胞内配体靶蛋白相互作用持久力的方法
US11442063B2 (en) * 2018-05-30 2022-09-13 Promega Corporation Broad spectrum kinase binding agents
CN113945670A (zh) * 2021-09-30 2022-01-18 上海中科新生命生物科技有限公司 一种基于化学蛋白质组学的激酶富集检测方法
CN116514724A (zh) * 2023-03-23 2023-08-01 上海康鹏科技股份有限公司 一种2,4-二氯-5-氟嘧啶的制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9119240D0 (en) * 1991-09-09 1991-10-23 Avalon Biosciences Ltd Enzyme capture assay for human secretory acetyl cholinesterase
IL106106A0 (en) * 1993-06-22 1993-10-20 Interpharm Lab Ltd Library of polymeric molecules and its preparation
US5536822A (en) 1994-03-09 1996-07-16 University Of Virginia Alumni Patents Foundation γ-phosphate linked adenosine 5' triphosphate sepharose
US6428956B1 (en) * 1998-03-02 2002-08-06 Isis Pharmaceuticals, Inc. Mass spectrometric methods for biomolecular screening
WO2000063694A1 (en) 1999-04-15 2000-10-26 University Of Virginia Patent Foundation Proteome mining
WO2001077684A2 (en) 2000-04-10 2001-10-18 The Scripps Research Institute Proteomic analysis using activity-based probe libraries
US20030143648A1 (en) 2001-11-29 2003-07-31 Cravatt Benjamin F. Enzyme activity profiles
US20030186221A1 (en) 2002-04-02 2003-10-02 Lockhart David J. Phage display affinity filter and forward screen
EP1494695A4 (en) * 2002-04-15 2006-01-25 American Nat Red Cross LIGANDS FOR BINDING TO PLASMA PROTEINS
ATE464392T1 (de) * 2002-07-11 2010-04-15 American Nat Red Cross Verfahren zur identifizierung einzelner aktiver einheiten aus komplexen gemischen
AU2003258542A1 (en) * 2002-07-29 2004-02-23 Axxima Pharmaceuticals Ag Method for isolating atp binding proteins by means of immobolized protein inhibitors

Also Published As

Publication number Publication date
EP2613154A3 (en) 2013-07-17
EP2613153A3 (en) 2014-05-21
EP2613153A2 (en) 2013-07-10
JP2008543296A (ja) 2008-12-04
CN101223447A (zh) 2008-07-16
PT1891446E (pt) 2013-06-12
ES2412380T3 (es) 2013-07-11
EP2613154A2 (en) 2013-07-10
JP4932835B2 (ja) 2012-05-16
EP1734367A1 (en) 2006-12-20
DE6763568T1 (de) 2011-09-22
SI1891446T1 (sl) 2013-07-31

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