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DK1890698T3 - Fremgangsmåde til fremstilling af et nikotinafgivelses-produkt - Google Patents

Fremgangsmåde til fremstilling af et nikotinafgivelses-produkt

Info

Publication number
DK1890698T3
DK1890698T3 DK06742444.0T DK06742444T DK1890698T3 DK 1890698 T3 DK1890698 T3 DK 1890698T3 DK 06742444 T DK06742444 T DK 06742444T DK 1890698 T3 DK1890698 T3 DK 1890698T3
Authority
DK
Denmark
Prior art keywords
nicotine
preparation
release product
mixture
nicotine release
Prior art date
Application number
DK06742444.0T
Other languages
English (en)
Inventor
Carsten Andersen
Original Assignee
Fertin Pharma As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fertin Pharma As filed Critical Fertin Pharma As
Application granted granted Critical
Publication of DK1890698T3 publication Critical patent/DK1890698T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • A61K47/585Ion exchange resins, e.g. polystyrene sulfonic acid resin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465Nicotine; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A61K9/0058Chewing gums
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34Tobacco-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Zoology (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK06742444.0T 2005-06-01 2006-06-01 Fremgangsmåde til fremstilling af et nikotinafgivelses-produkt DK1890698T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200500796 2005-06-01
PCT/DK2006/000307 WO2006128468A1 (en) 2005-06-01 2006-06-01 A method of manufacturing a nicotine delivery product

Publications (1)

Publication Number Publication Date
DK1890698T3 true DK1890698T3 (da) 2010-03-29

Family

ID=36778046

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06742444.0T DK1890698T3 (da) 2005-06-01 2006-06-01 Fremgangsmåde til fremstilling af et nikotinafgivelses-produkt

Country Status (6)

Country Link
US (1) US8986668B2 (da)
EP (1) EP1890698B1 (da)
AT (1) ATE448786T1 (da)
DE (1) DE602006010542D1 (da)
DK (1) DK1890698T3 (da)
WO (1) WO2006128468A1 (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8642016B2 (en) 2006-07-21 2014-02-04 Jsrnti, Llc Medicinal delivery system, and related methods
US20110268809A1 (en) 2010-04-28 2011-11-03 Paul Andrew Brinkley Nicotine-Containing Pharmaceutical Compositions
US20110274628A1 (en) 2010-05-07 2011-11-10 Borschke August J Nicotine-containing pharmaceutical compositions
WO2011150959A1 (en) * 2010-05-31 2011-12-08 Fertin Pharma A/S Formulation comprising nicotine and a cation exchange resin
WO2011150960A1 (en) * 2010-05-31 2011-12-08 Fertin Pharma A/S Formulation comprising nicotine and a cation exchange resin
US20130078307A1 (en) 2011-09-22 2013-03-28 Niconovum Usa, Inc. Nicotine-containing pharmaceutical composition
US9084439B2 (en) 2011-09-22 2015-07-21 R.J. Reynolds Tobacco Company Translucent smokeless tobacco product
US9474303B2 (en) 2011-09-22 2016-10-25 R.J. Reynolds Tobacco Company Translucent smokeless tobacco product
US9629392B2 (en) 2011-09-22 2017-04-25 R.J. Reynolds Tobacco Company Translucent smokeless tobacco product
US9907748B2 (en) 2011-10-21 2018-03-06 Niconovum Usa, Inc. Excipients for nicotine-containing therapeutic compositions
US9763928B2 (en) 2012-02-10 2017-09-19 Niconovum Usa, Inc. Multi-layer nicotine-containing pharmaceutical composition
US20140255452A1 (en) 2013-03-11 2014-09-11 Niconovum Usa, Inc. Method and apparatus for differentiating oral pouch products
US10130120B2 (en) 2013-03-15 2018-11-20 Altria Client Services Llc Use of pectin or other anionic polymers in the stabilization and controlled release of nicotine in oral sensorial tobacco products or nicotine containing non-tobacco oral sensorial products
US20170165252A1 (en) 2015-12-10 2017-06-15 Niconovum Usa Inc. Protein-enriched therapeutic composition
EP3445344B1 (en) 2016-04-21 2020-08-19 Fertin Pharma A/S Nicotine delivery product, related uses and oral dosage forms, and methods of production
WO2018233795A1 (en) * 2017-06-23 2018-12-27 Fertin Pharma A/S Nicotine pouch
EP3807260B1 (en) 2018-06-15 2024-09-18 R. J. Reynolds Tobacco Company Purification of nicotine

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3901248A (en) 1970-07-22 1975-08-26 Leo Ab Chewable smoking substitute composition
US3845217A (en) * 1972-11-16 1974-10-29 Helsingborg L Ab Buffered smoking substitute compositions
US6607752B2 (en) 2000-07-27 2003-08-19 Rohm And Haas Company Method for the anhydrous loading of nicotine onto ion exchange resins
WO2003061709A1 (en) * 2002-01-18 2003-07-31 Advanced Phytonics Limited A method for preparing resinates
US6586449B1 (en) * 2002-05-28 2003-07-01 Cambrex Charles City, Inc. Nicotine-containing, controlled release composition and method
ATE439839T1 (de) * 2003-12-02 2009-09-15 Fertin Pharma As Nikotin-abgabeprodukt und herstellungsverfahren

Also Published As

Publication number Publication date
DE602006010542D1 (de) 2009-12-31
WO2006128468A1 (en) 2006-12-07
EP1890698A1 (en) 2008-02-27
US20090092573A1 (en) 2009-04-09
EP1890698B1 (en) 2009-11-18
ATE448786T1 (de) 2009-12-15
US8986668B2 (en) 2015-03-24

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