DK1733039T3 - Forbedret bakteriel værtscelle til direkte ekspression af peptider - Google Patents

Forbedret bakteriel værtscelle til direkte ekspression af peptider

Info

Publication number: DK1733039T3
Authority: DK; Denmark
Prior art keywords: peptides; host cell; bacterial host; direct expression; improved bacterial
Prior art date: 2004-03-12

Application number

DK05734021.8T

Other languages

English (en)

Inventor

Nozer M Mehta

Angelo P Consalvo

Martha V L Ray

Christopher P Meenan

Original Assignee

Enteris Biopharma Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-03-12

Filing date

2005-03-10

Publication date

2014-01-06

2005-03-10 Application filed by Enteris Biopharma Inc filed Critical Enteris Biopharma Inc

2014-01-06 Application granted granted Critical

2014-01-06 Publication of DK1733039T3 publication Critical patent/DK1733039T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/635—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
Zoology (AREA)
Engineering & Computer Science (AREA)
Wood Science & Technology (AREA)
General Health & Medical Sciences (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Bioinformatics & Cheminformatics (AREA)
Biotechnology (AREA)
Endocrinology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
General Engineering & Computer Science (AREA)
Biophysics (AREA)
Medicinal Chemistry (AREA)
Gastroenterology & Hepatology (AREA)
Toxicology (AREA)
Microbiology (AREA)
Biomedical Technology (AREA)
Physics & Mathematics (AREA)
Plant Pathology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Diabetes (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

DK05734021.8T 2004-03-12 2005-03-10 Forbedret bakteriel værtscelle til direkte ekspression af peptider DK1733039T3 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US55282404P	2004-03-12	2004-03-12
US11/076,260 US8227241B2 (en)	2004-03-12	2005-03-09	Bacterial host cell for the direct expression of peptides
PCT/US2005/007873 WO2005089182A2 (en)	2004-03-12	2005-03-10	Improved bacterial host cell for the direct expression of peptides

Publications (1)

Publication Number	Publication Date
DK1733039T3 true DK1733039T3 (da)	2014-01-06

Family

ID=34994183

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DK09156191.0T DK2067854T3 (da)	2004-03-12	2005-03-10	Kloningsvektorer
DK05734021.8T DK1733039T3 (da)	2004-03-12	2005-03-10	Forbedret bakteriel værtscelle til direkte ekspression af peptider

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
DK09156191.0T DK2067854T3 (da)	2004-03-12	2005-03-10	Kloningsvektorer

Country Status (9)

Country	Link
US (6)	US8227241B2 (da)
EP (2)	EP2067854B1 (da)
JP (2)	JP5591447B2 (da)
CN (3)	CN101389750B (da)
AU (2)	AU2005222860A1 (da)
CA (2)	CA2795418C (da)
DK (2)	DK2067854T3 (da)
ES (2)	ES2440658T3 (da)
WO (1)	WO2005089182A2 (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US8227241B2 (en) *	2004-03-12	2012-07-24	Unigene Laboratories, Inc.	Bacterial host cell for the direct expression of peptides
US7445911B2 (en) *	2004-11-24	2008-11-04	Unigene Laboratories Inc.	Enzymatic reactions in the presence of keto acids
CA2613471C (en)	2005-06-24	2016-09-06	Unigene Laboratories, Inc.	Cell lines for expressing enzyme useful in the preparation of amidated products
PT2061897T (pt)	2006-07-27	2020-05-08	Wyeth Llc	Processo de fermentação em lote alimentado de densidade celular elevada para produção de proteína recombinante
US8377863B2 (en)	2007-05-29	2013-02-19	Unigene Laboratories Inc.	Peptide pharmaceutical for oral delivery
WO2013052168A2 (en) *	2011-05-26	2013-04-11	Georgetown University	Detection aib1-delta 4 protein
US20150353940A1 (en) *	2013-08-05	2015-12-10	Absci, Llc	Vectors for use in an inducible coexpression system
AU2014225822B2 (en)	2013-03-05	2017-05-04	Enteris Biopharma, Inc.	Pharmaceuticals for oral delivery
BR112016002622B1 (pt)	2013-08-20	2023-04-11	Lek Pharmaceuticals D.D	Meio de cultura celular e uso de selênio
CN103911390B (zh) *	2014-04-24	2017-02-15	江南大学	一种通过调节OmpA表达提高大肠杆菌黄酮类物质耐受性的方法
AU2016206950B2 (en)	2015-01-12	2021-05-06	Enteris Biopharma, Inc.	Solid oral dosage forms
WO2017120347A1 (en)	2016-01-06	2017-07-13	Oncobiologics, Inc.	Modulation of afucosylated species in a monoclonal antibody composition
WO2017136433A1 (en)	2016-02-03	2017-08-10	Oncobiologics, Inc.	Buffer formulations for enhanced antibody stability
CN107365779A (zh) *	2017-08-22	2017-11-21	中国科学院天津工业生物技术研究所	利用谷氨酸棒状杆菌生产紫色杆菌素的方法
IL276910B2 (en)	2018-03-26	2025-11-01	Amgen Inc	Total afucosylated glycoforms of antibodies produced in cell culture
CN111954683A (zh)	2018-04-05	2020-11-17	生物辐射Abd瑟罗泰克有限公司	感兴趣的蛋白质的展示系统
AU2020243460A1 (en)	2019-03-18	2021-10-07	Bio-Rad Abd Serotec Gmbh	Protection of SpyTag-containing periplasmic fusion proteins from protease Tsp and ompT degradation
CN114875063A (zh) *	2022-02-28	2022-08-09	华侨大学	一种提高植物基础抗逆的方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4595658A (en)	1982-09-13	1986-06-17	The Rockefeller University	Method for facilitating externalization of proteins synthesized in bacteria
DE3586386T2 (de)	1984-10-05	1993-01-14	Genentech Inc	Dna, zellkulturen und verfahren zur sekretion von heterologen proteinen und periplasmische proteinrueckgewinnung.
US5223407A (en)	1988-08-31	1993-06-29	Allelix Inc.	Excretion of heterologous proteins from e. coli
US5264365A (en) *	1990-11-09	1993-11-23	Board Of Regents, The University Of Texas System	Protease-deficient bacterial strains for production of proteolytically sensitive polypeptides
US6201925B1 (en) *	1996-11-15	2001-03-13	Futuretel, Inc.	Method and apparatus for editing video files
DK1005526T3 (da)	1997-04-16	2011-02-07	Unigene Lab Inc	Direkte ekspression af peptider i kulturmedium
CN1233820C (zh)	2000-12-14	2005-12-28	杰南技术公司	细菌宿主菌株
EP1279739A1 (en) *	2001-07-26	2003-01-29	Vrije Universiteit Brussel	Recombinant vectors derived from adeno-associated virus expressing TAM67 for gene therapy
US8227241B2 (en) *	2004-03-12	2012-07-24	Unigene Laboratories, Inc.	Bacterial host cell for the direct expression of peptides

2005
- 2005-03-09 US US11/076,260 patent/US8227241B2/en not_active Expired - Fee Related
- 2005-03-10 EP EP09156191.0A patent/EP2067854B1/en not_active Expired - Lifetime
- 2005-03-10 WO PCT/US2005/007873 patent/WO2005089182A2/en not_active Ceased
- 2005-03-10 CN CN200580007801XA patent/CN101389750B/zh not_active Expired - Fee Related
- 2005-03-10 DK DK09156191.0T patent/DK2067854T3/da active
- 2005-03-10 DK DK05734021.8T patent/DK1733039T3/da active
- 2005-03-10 EP EP05734021.8A patent/EP1733039B1/en not_active Expired - Lifetime
- 2005-03-10 CN CN201110107199.4A patent/CN102337241B/zh not_active Expired - Fee Related
- 2005-03-10 CN CN2011101072554A patent/CN102337286A/zh active Pending
- 2005-03-10 AU AU2005222860A patent/AU2005222860A1/en not_active Abandoned
- 2005-03-10 JP JP2007502979A patent/JP5591447B2/ja not_active Expired - Fee Related
- 2005-03-10 ES ES05734021.8T patent/ES2440658T3/es not_active Expired - Lifetime
- 2005-03-10 CA CA2795418A patent/CA2795418C/en not_active Expired - Fee Related
- 2005-03-10 CA CA2557295A patent/CA2557295C/en not_active Expired - Fee Related
- 2005-03-10 ES ES09156191.0T patent/ES2528754T3/es not_active Expired - Lifetime
2007
- 2007-10-30 US US11/928,994 patent/US8252580B2/en not_active Expired - Fee Related
- 2007-10-30 US US11/928,936 patent/US8216822B2/en not_active Expired - Fee Related
- 2007-10-30 US US11/929,079 patent/US7553655B2/en not_active Expired - Fee Related
- 2007-10-30 US US11/929,028 patent/US7541174B2/en not_active Expired - Fee Related
2009
- 2009-02-06 AU AU2009200466A patent/AU2009200466B2/en not_active Ceased
2010
- 2010-05-06 JP JP2010106525A patent/JP2010162051A/ja active Pending
2012
- 2012-07-09 US US13/544,228 patent/US8835161B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
CN102337286A (zh)	2012-02-01
ES2440658T3 (es)	2014-01-29
EP2067854A1 (en)	2009-06-10
CA2795418A1 (en)	2005-09-29
DK2067854T3 (da)	2015-01-26
US20080057566A1 (en)	2008-03-06
US8216822B2 (en)	2012-07-10
US20050221442A1 (en)	2005-10-06
CN101389750A (zh)	2009-03-18
US8252580B2 (en)	2012-08-28
CA2557295A1 (en)	2005-09-29
US7541174B2 (en)	2009-06-02
CN102337241A (zh)	2012-02-01
EP1733039A4 (en)	2008-09-24
WO2005089182A3 (en)	2007-12-13
CN102337241B (zh)	2014-12-03
CA2557295C (en)	2013-01-29
AU2009200466A1 (en)	2009-02-26
US8227241B2 (en)	2012-07-24
US8835161B2 (en)	2014-09-16
JP2007535313A (ja)	2007-12-06
ES2528754T3 (es)	2015-02-12
CA2795418C (en)	2015-02-24
AU2009200466B2 (en)	2012-03-15
US20080102509A1 (en)	2008-05-01
EP1733039B1 (en)	2013-09-25
WO2005089182A2 (en)	2005-09-29
JP5591447B2 (ja)	2014-09-17
US7553655B2 (en)	2009-06-30
US20130034897A1 (en)	2013-02-07
JP2010162051A (ja)	2010-07-29
US20080102510A1 (en)	2008-05-01
EP2067854B1 (en)	2014-11-05
EP1733039A2 (en)	2006-12-20
AU2005222860A1 (en)	2005-09-29
CN101389750B (zh)	2012-07-11
AU2009200466A2 (en)	2009-03-12
US20080102491A1 (en)	2008-05-01

Publication	Publication Date	Title
DK1733039T3 (da)	2014-01-06	Forbedret bakteriel værtscelle til direkte ekspression af peptider
EP2007904A4 (en)	2009-06-10	PROPAGATION OF PRIMARY CELLS
DK2213724T3 (da)	2012-10-15	Medium frit for dyreprotein til dyrkning af celler
PL2634243T3 (pl)	2018-02-28	Ulepszony sposób hodowli komórkowej
ATE479434T1 (de)	2010-09-15	Als protein-kinase-inhibitoren nutzbare dyhydrodiazepine
DK2046826T3 (da)	2011-10-24	Exendin-fusionsproteiner
DK2030981T3 (da)	2014-10-13	Forbindelser til proteasom-enzymhæmning
DK1759192T3 (da)	2021-05-03	Heterogene membranelektroder
ATE401893T1 (de)	2008-08-15	Thiophenepyrimidinone als 17-beta-hydroxysteroid dehydrogenase inhibitoren
DK3287525T3 (da)	2020-01-20	RNA-præparater omfattende oprenset modificeret RNA til omprogrammering af celler
NL1029799A1 (nl)	2006-02-28	Enantiomeer zuivere aminoheteroarylverbindingen als proteïnekinaseremmers.
DK2061803T4 (da)	2022-12-05	Fremgangsmåde til oprensning af fc-holdige proteiner
DK1829959T3 (da)	2013-07-08	Rekombinant mikroorganisme
EP2212435A4 (en)	2010-11-03	FUSIONED GENE BZW. FUSIONED GENES
DK2573166T3 (da)	2016-07-04	Fremgangsmåder til fremstilling af T-celler til celleterapi
EP1735335A4 (en)	2007-12-12	Cell-killing peptide
IS8570A (is)	2006-11-20	Stoðfrumulaus framhaldsrækt stofnfrumna
EP1766389A4 (en)	2008-08-27	METHOD OF ISOLATING CELLS
DK1809660T3 (da)	2014-10-20	Thymus-specifikt protein
ATE397618T1 (de)	2008-06-15	Peptidcyclisierung
EP1981537A4 (en)	2009-06-17	HCV-SPECIFIC T CELL ACTIVATION
DE502005000305D1 (de)	2007-02-22	Photobioreaktor
ATE546152T1 (de)	2012-03-15	Bakteriocin-vermittler-peptide
DE112006003688A5 (de)	2008-10-23	Abdeckung von Solarzellen
FI20050753L (fi)	2006-03-04	Uudet peptidit