DK178386A - Rekombinant dna-udtrykkelsesvektor og dna-forbindelser, der udtrykker isopenicillin n synthetase - Google Patents

Rekombinant dna-udtrykkelsesvektor og dna-forbindelser, der udtrykker isopenicillin n synthetase Download PDF

Info

Publication number: DK178386A
Authority: DK; Denmark
Prior art keywords: isopenicillin; synthetase; expression vector; dna; recombinant dna
Prior art date: 1985-04-22

Application number

DK178386A

Other languages

Afrikaans (af)

English (en)

Other versions

DK178386D0 (da

Inventor

Thomas Dominick Ingolia

Stephen Wyatt Queener

Suellen Mary Samson

Paul Luther Skatrud

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-04-22

Filing date

1986-04-18

Publication date

1986-10-23

1986-04-18 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

1986-04-18 Publication of DK178386D0 publication Critical patent/DK178386D0/da

1986-10-23 Publication of DK178386A publication Critical patent/DK178386A/da

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/93—Ligases (6)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
- C12N15/69—Increasing the copy number of the vector
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi

Landscapes

Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Biomedical Technology (AREA)
General Engineering & Computer Science (AREA)
Biotechnology (AREA)
Molecular Biology (AREA)
General Health & Medical Sciences (AREA)
Microbiology (AREA)
Biochemistry (AREA)
Physics & Mathematics (AREA)
Biophysics (AREA)
Plant Pathology (AREA)
Mycology (AREA)
Medicinal Chemistry (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Enzymes And Modification Thereof (AREA)
Saccharide Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

Description

DK178386A 1985-04-22 1986-04-18 Rekombinant dna-udtrykkelsesvektor og dna-forbindelser, der udtrykker isopenicillin n synthetase DK178386A (da)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date
US72587085A	1985-04-22	1985-04-22
US72587085		1985-04-22
US79938485A	1985-11-18	1985-11-18
US79938485		1985-11-18

Publications (2)

Publication Number	Publication Date
DK178386D0 DK178386D0 (da)	1986-04-18
DK178386A true DK178386A (da)	1986-10-23

Family

ID=27111238

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK178386A DK178386A (da)	1985-04-22	1986-04-18	Rekombinant dna-udtrykkelsesvektor og dna-forbindelser, der udtrykker isopenicillin n synthetase

Country Status (14)

Country	Link
EP (1)	EP0200425B1 (da)
JP (1)	JPH0787788B2 (da)
KR (1)	KR860008287A (da)
CN (1)	CN86102604A (da)
AU (2)	AU592791B2 (da)
BG (2)	BG45047A3 (da)
CA (1)	CA1309673C (da)
DE (1)	DE3683080D1 (da)
DK (1)	DK178386A (da)
ES (3)	ES8800344A1 (da)
FI (1)	FI95810C (da)
HU (1)	HU202279B (da)
IE (1)	IE58780B1 (da)
IL (1)	IL78531A0 (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU564690B2 (en)	1980-04-03	1987-08-20	Biogen Idec Ma Inc.	Process for producing human fibroblast interferon-like polypeptides using recombinant dna
GB8508800D0 (en) *	1985-04-04	1985-05-09	Glaxo Group Ltd	Microbiological process
US4892819A (en) *	1985-11-25	1990-01-09	Eli Lilly And Company	Recombinant DNA expression vectors and DNA compounds that encode isopenicillin N synthetase from penicillium chrysogenum
EP0233715B1 (en) *	1986-01-31	1994-05-25	BEECHAM GROUP plc	Isolation and expression of genes involved in the biosynthesis of beta-lactams
IL85535A (en) *	1987-03-04	1994-02-27	Lilly Co Eli	Recombinant dna expression vectors and dna compounds that encode deacetoxycephalosporin c synthetase and deacetylcephalosporin c synthetase
GB2208077A (en) *	1987-04-24	1989-02-22	Antibioticos Sa	Isopenicillin n synthetase gene derived from aspergillus nidulans
EP0303364A1 (en) *	1987-08-10	1989-02-15	The Governors of the University of Alberta	Cloning and nucleotide sequence determination of the isopenicillin N synthetase gene from streptomyces clavuligerus
US4885252A (en) *	1987-09-08	1989-12-05	Eli Lilly And Company	Recombinant DNA expression vectors and DNA compounds that encode isopenicillin N synthetase from aspergillus nidulans
US4950603A (en) *	1987-11-02	1990-08-21	Eli Lilly And Company	Recombinant DNA expression vectors and DNA compounds that encode isopenicillin N synthetase from Streptomyces lipmanii
GB8728811D0 (en) *	1987-12-09	1988-01-27	Beecham Group Plc	Novel substance
US6258555B1 (en)	1987-12-09	2001-07-10	Beecham Group P.L.C.	DNA encoding ACV synthetase
KR0171897B1 (ko) *	1989-12-27	1999-02-01	후지사와 도모끼찌로	7-아미노세펨 화합물 또는 그 염류의 제조 방법
ATE180279T1 (de) *	1990-01-12	1999-06-15	Glaxo Group Ltd	Für ein enzym der antibiotika-biosynthese kodierende dna-sequenz
AU3517895A (en) *	1994-09-28	1996-04-19	Novo Nordisk A/S	Process for the production of secondary metabolites
DE19755302A1 (de) *	1997-12-12	1999-06-17	Hoechst Marion Roussel De Gmbh	Neuer Transkriptionsfaktor CPCR1 zur Regulation des Isopenicillin N-Synthetase-Gens (pcbC) und des AC-/ACV-Synthetase-Gens (pcbAB)
EP1165546A2 (en)	1999-04-02	2002-01-02	Du Pont Pharmaceuticals Company	Novel lactam inhibitors of matrix metalloproteinases, tnf-alpha, and aggrecanase

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3330003A1 (de) *	1982-10-21	1984-10-31	Gesellschaft für Biotechnologische Forschung mbH (GBF), 3300 Braunschweig	Dna-sequenz und dna-strukturen und sie verwendendes verfahren zur herstellung von penicillin-acylase
CA1278540C (en) *	1983-07-22	1991-01-02	Eli Lilly And Company	Modified antibiotic resistance gene
US4762786A (en) *	1984-09-27	1988-08-09	Eli Lilly And Company	Vectors and conditions which allow genetic transformation of cephalosporium
GB8508800D0 (en) *	1985-04-04	1985-05-09	Glaxo Group Ltd	Microbiological process
US4892819A (en) *	1985-11-25	1990-01-09	Eli Lilly And Company	Recombinant DNA expression vectors and DNA compounds that encode isopenicillin N synthetase from penicillium chrysogenum

1986
- 1986-04-17 EP EP86302873A patent/EP0200425B1/en not_active Expired - Lifetime
- 1986-04-17 IL IL78531A patent/IL78531A0/xx not_active IP Right Cessation
- 1986-04-17 CA CA000506967A patent/CA1309673C/en not_active Expired - Lifetime
- 1986-04-17 DE DE8686302873T patent/DE3683080D1/de not_active Expired - Lifetime
- 1986-04-18 FI FI861653A patent/FI95810C/fi not_active IP Right Cessation
- 1986-04-18 IE IE102986A patent/IE58780B1/en not_active IP Right Cessation
- 1986-04-18 BG BG074576A patent/BG45047A3/xx unknown
- 1986-04-18 BG BG078442A patent/BG45219A3/xx unknown
- 1986-04-18 DK DK178386A patent/DK178386A/da not_active Application Discontinuation
- 1986-04-21 ES ES554218A patent/ES8800344A1/es not_active Expired
- 1986-04-21 AU AU56431/86A patent/AU592791B2/en not_active Ceased
- 1986-04-21 CN CN198686102604A patent/CN86102604A/zh active Pending
- 1986-04-21 KR KR1019860003061A patent/KR860008287A/ko not_active Ceased
- 1986-04-21 HU HU861666A patent/HU202279B/hu not_active IP Right Cessation
- 1986-04-21 JP JP61093178A patent/JPH0787788B2/ja not_active Expired - Fee Related
1987
- 1987-08-11 ES ES557658A patent/ES8802585A1/es not_active Expired
1988
- 1988-04-15 ES ES557829A patent/ES8900142A1/es not_active Expired
1989
- 1989-09-27 AU AU42347/89A patent/AU619596B2/en not_active Ceased

Also Published As

Publication number	Publication date
KR860008287A (ko)	1986-11-14
IE861029L (en)	1986-10-22
CN86102604A (zh)	1986-11-26
FI861653A7 (fi)	1986-10-23
AU619596B2 (en)	1992-01-30
JPH0787788B2 (ja)	1995-09-27
ES557658A0 (es)	1988-08-16
DE3683080D1 (de)	1992-02-06
AU5643186A (en)	1986-10-30
FI95810B (fi)	1995-12-15
JPS61254192A (ja)	1986-11-11
CA1309673C (en)	1992-11-03
FI95810C (fi)	1996-03-25
EP0200425A2 (en)	1986-11-05
ES557829A0 (es)	1989-01-16
FI861653A0 (fi)	1986-04-18
BG45047A3 (bg)	1989-03-15
AU4234789A (en)	1990-01-11
ES8900142A1 (es)	1989-01-16
IL78531A0 (en)	1986-08-31
BG45219A3 (bg)	1989-04-14
HUT40705A (en)	1987-01-28
ES8802585A1 (es)	1988-08-16
ES8800344A1 (es)	1987-11-01
IE58780B1 (en)	1993-11-17
HU202279B (en)	1991-02-28
AU592791B2 (en)	1990-01-25
EP0200425B1 (en)	1991-12-27
DK178386D0 (da)	1986-04-18
EP0200425A3 (en)	1988-07-06
ES554218A0 (es)	1987-11-01

Publication	Publication Date	Title
DK217889D0 (da)	1989-05-03	Rekombinant-dna-udtrykkelsesvektorer og dna-forbindelser, der koder for desacetoxycephalosporin c synthetase
DK178386A (da)	1986-10-23	Rekombinant dna-udtrykkelsesvektor og dna-forbindelser, der udtrykker isopenicillin n synthetase
DK188686A (da)	1986-10-27	Vindmaelle
DK180486A (da)	1986-10-20	Varmeapparat
DK110885D0 (da)	1985-03-11	Nucleinsyre-proteinkonjugater, disses anvendelse samt fremgangsmaade til fremstilling heraf
NO891818D0 (no)	1989-05-02	T4-reseptor-protein, relaterte dna-sekvenser samt fremstilling derav.
FI863096L (fi)	1987-02-01	Absorberande material, helst anvaendning i engaongsartiklar saosom bloejor, sanitetsbindor eller saorfoerband.
DE3685913D1 (de)	1992-08-13	Vektorenverarbeitung.
DK122687A (da)	1987-09-15	Polypeptid, dna og anvendelse deraf
DE3781140D1 (de)	1992-09-17	Plattenfoermige, ionenempfindliche elektrode.
DE3674675D1 (de)	1990-11-08	Klassifizierung von stahl.
DK102088A (da)	1988-12-16	Rekombinant-dna-udtrykkelsesvektorer og dna-produkter, der koder deacetoxycephalosporin c syntetase og deacetylsephalosporin c synthetase
DK300787A (da)	1987-12-14	Dna-struktur fra cytomegalivirus, ekspressionsvektor derfor samt dermed kodede proteinstrukturer og disses anvendelse
NO872174D0 (no)	1987-05-25	Polypetidpreparater med oekt biologisk tilgjengelighet.
DK606088D0 (da)	1988-10-31	Rekombinant-dna-udtrykkelsesvektorer og dna-forbindelser, der koder for isopenicillin n synthetase
FI860677A7 (fi)	1986-08-16	Rhinoviruskannan HRV2 polypeptidi ja sitä koodaava DNA-molekyyli.
DK224985A (da)	1985-11-22	Peptider, og midler indeholdende peptiderne
IL88095A0 (en)	1989-06-30	Dna sequences,proteins and gene preparations
FI864070A0 (fi)	1986-10-08	Sammansatt keramiskt material och foder foer metallurgiska smaeltugnar, i vilka anvaends sammansatta keramiska material.
NO905561D0 (no)	1990-12-21	Proteiner og nukleinsyrer.
DE3682358D1 (de)	1991-12-12	Expressionsvektoren zur verwendung in e. coli.
DK199985A (da)	1986-07-26	Roerboejle
DK493788D0 (da)	1988-09-06	Rekombinant-dna-udtrykkelsesvektorer og dna-forbi ndelser, der indkoder isopenicillin n synthetase fra aspergillus nidulans
NO833542L (no)	1984-04-02	Nytt dna og rekombinantplasmid inneholdende samme
EP0245459A4 (en)	1989-04-27	T CELL LYMPHOTROPHIC VIRUS PROTEIN AND TEST PROCEDURE.

Legal Events

Date	Code	Title	Description
2004-12-27	AHS	Application shelved for other reasons than non-payment