DK1610768T3 - Matrikskompositioner til styret afgivelse af lægemiddelsubstanser - Google Patents
Matrikskompositioner til styret afgivelse af lægemiddelsubstanserInfo
- Publication number
- DK1610768T3 DK1610768T3 DK04723523T DK04723523T DK1610768T3 DK 1610768 T3 DK1610768 T3 DK 1610768T3 DK 04723523 T DK04723523 T DK 04723523T DK 04723523 T DK04723523 T DK 04723523T DK 1610768 T3 DK1610768 T3 DK 1610768T3
- Authority
- DK
- Denmark
- Prior art keywords
- polymer
- polyethylene
- ethylene
- matrix composition
- styrene
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 7
- 239000011159 matrix material Substances 0.000 title abstract 6
- 229940088679 drug related substance Drugs 0.000 title 1
- 229920000642 polymer Polymers 0.000 abstract 7
- 239000011248 coating agent Substances 0.000 abstract 3
- 238000000576 coating method Methods 0.000 abstract 3
- LYCAIKOWRPUZTN-UHFFFAOYSA-N ethylene glycol Natural products OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 abstract 3
- VSKJLJHPAFKHBX-UHFFFAOYSA-N 2-methylbuta-1,3-diene;styrene Chemical compound CC(=C)C=C.C=CC1=CC=CC=C1.C=CC1=CC=CC=C1 VSKJLJHPAFKHBX-UHFFFAOYSA-N 0.000 abstract 2
- 229920003171 Poly (ethylene oxide) Polymers 0.000 abstract 2
- FACXGONDLDSNOE-UHFFFAOYSA-N buta-1,3-diene;styrene Chemical compound C=CC=C.C=CC1=CC=CC=C1.C=CC1=CC=CC=C1 FACXGONDLDSNOE-UHFFFAOYSA-N 0.000 abstract 2
- 229920001577 copolymer Polymers 0.000 abstract 2
- 238000002844 melting Methods 0.000 abstract 2
- 230000008018 melting Effects 0.000 abstract 2
- -1 polyethylene Polymers 0.000 abstract 2
- 229920001223 polyethylene glycol Polymers 0.000 abstract 2
- 229920000468 styrene butadiene styrene block copolymer Polymers 0.000 abstract 2
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 abstract 1
- 229920006022 Poly(L-lactide-co-glycolide)-b-poly(ethylene glycol) Polymers 0.000 abstract 1
- 239000004952 Polyamide Substances 0.000 abstract 1
- 239000004698 Polyethylene Substances 0.000 abstract 1
- 229920000954 Polyglycolide Polymers 0.000 abstract 1
- 229920000331 Polyhydroxybutyrate Polymers 0.000 abstract 1
- GOOHAUXETOMSMM-UHFFFAOYSA-N Propylene oxide Chemical compound CC1CO1 GOOHAUXETOMSMM-UHFFFAOYSA-N 0.000 abstract 1
- 239000004809 Teflon Substances 0.000 abstract 1
- 229920006362 Teflon® Polymers 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 229920001400 block copolymer Polymers 0.000 abstract 1
- 210000001124 body fluid Anatomy 0.000 abstract 1
- 239000010839 body fluid Substances 0.000 abstract 1
- 229920002301 cellulose acetate Polymers 0.000 abstract 1
- 238000013270 controlled release Methods 0.000 abstract 1
- 239000006185 dispersion Substances 0.000 abstract 1
- 239000005038 ethylene vinyl acetate Substances 0.000 abstract 1
- 238000001125 extrusion Methods 0.000 abstract 1
- 239000012530 fluid Substances 0.000 abstract 1
- 239000004816 latex Substances 0.000 abstract 1
- 229920000126 latex Polymers 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229920001983 poloxamer Polymers 0.000 abstract 1
- 239000005015 poly(hydroxybutyrate) Substances 0.000 abstract 1
- 229920000218 poly(hydroxyvalerate) Polymers 0.000 abstract 1
- 229920000747 poly(lactic acid) Polymers 0.000 abstract 1
- 229920002647 polyamide Polymers 0.000 abstract 1
- 229920000573 polyethylene Polymers 0.000 abstract 1
- 229920000139 polyethylene terephthalate Polymers 0.000 abstract 1
- 239000005020 polyethylene terephthalate Substances 0.000 abstract 1
- 239000004633 polyglycolic acid Substances 0.000 abstract 1
- 239000004626 polylactic acid Substances 0.000 abstract 1
- 229920001451 polypropylene glycol Polymers 0.000 abstract 1
- 229920002635 polyurethane Polymers 0.000 abstract 1
- 239000004814 polyurethane Substances 0.000 abstract 1
- 229920002689 polyvinyl acetate Polymers 0.000 abstract 1
- 239000011118 polyvinyl acetate Substances 0.000 abstract 1
- 229920000915 polyvinyl chloride Polymers 0.000 abstract 1
- 239000004800 polyvinyl chloride Substances 0.000 abstract 1
- 229920002379 silicone rubber Polymers 0.000 abstract 1
- 239000004945 silicone rubber Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0092—Hollow drug-filled fibres, tubes of the core-shell type, coated fibres, coated rods, microtubules or nanotubes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2893—Tablet coating processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nanotechnology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200300464 | 2003-03-26 | ||
| PCT/DK2003/000765 WO2004041252A1 (en) | 2002-11-08 | 2003-11-07 | Controlled release carvedilol compositions |
| PCT/DK2004/000217 WO2004084869A1 (en) | 2003-03-26 | 2004-03-26 | Matrix compositions for controlled delivery of drug substances |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1610768T3 true DK1610768T3 (da) | 2008-09-22 |
Family
ID=33099580
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK04723523T DK1610768T3 (da) | 2003-03-26 | 2004-03-26 | Matrikskompositioner til styret afgivelse af lægemiddelsubstanser |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US8298581B2 (da) |
| EP (3) | EP1974726B1 (da) |
| JP (1) | JP4989217B2 (da) |
| AT (2) | ATE454886T1 (da) |
| CA (1) | CA2520312C (da) |
| DE (2) | DE602004014747D1 (da) |
| DK (1) | DK1610768T3 (da) |
| ES (1) | ES2307003T3 (da) |
| WO (1) | WO2004084869A1 (da) |
Families Citing this family (103)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1067910T3 (da) * | 1998-04-03 | 2004-10-04 | Egalet As | Komposition med styret afgivelse |
| DE10026698A1 (de) * | 2000-05-30 | 2001-12-06 | Basf Ag | Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung |
| WO2003024430A1 (en) | 2001-09-21 | 2003-03-27 | Egalet A/S | Morphine polymer release system |
| EP2957281A1 (en) | 2001-09-21 | 2015-12-23 | Egalet Ltd. | Polymer release system |
| US7776314B2 (en) | 2002-06-17 | 2010-08-17 | Grunenthal Gmbh | Abuse-proofed dosage system |
| US20040151772A1 (en) * | 2002-11-08 | 2004-08-05 | Egalet A/S | Controlled release carvedilol compositions |
| DE602004031096D1 (de) * | 2003-03-26 | 2011-03-03 | Egalet As | Morphin-system mit kontrollierter freisetzung |
| ATE454886T1 (de) * | 2003-03-26 | 2010-01-15 | Egalet As | Matrixzubereitungen für die kontrollierte darreichung von arzneistoffen |
| DE102004032051A1 (de) | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten, festen Darreichungsform |
| US8075872B2 (en) | 2003-08-06 | 2011-12-13 | Gruenenthal Gmbh | Abuse-proofed dosage form |
| DE10336400A1 (de) | 2003-08-06 | 2005-03-24 | Grünenthal GmbH | Gegen Missbrauch gesicherte Darreichungsform |
| DE102005005446A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Bruchfeste Darreichungsformen mit retardierter Freisetzung |
| DE10361596A1 (de) | 2003-12-24 | 2005-09-29 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
| US20070048228A1 (en) | 2003-08-06 | 2007-03-01 | Elisabeth Arkenau-Maric | Abuse-proofed dosage form |
| US8377952B2 (en) * | 2003-08-28 | 2013-02-19 | Abbott Laboratories | Solid pharmaceutical dosage formulation |
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| US7201920B2 (en) | 2003-11-26 | 2007-04-10 | Acura Pharmaceuticals, Inc. | Methods and compositions for deterring abuse of opioid containing dosage forms |
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| DE102005005449A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
| US20060252831A1 (en) * | 2005-05-06 | 2006-11-09 | Christopher Offen | Method for the treatment of magnesium and potassium deficiencies |
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| KR100932613B1 (ko) * | 2007-04-27 | 2009-12-17 | 한남대학교 산학협력단 | 고분자 용융공정을 이용한 약물전달용 생체적합성 고분자나노 미립구의 제조방법 및 그 나노 미립구 |
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-
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- 2004-03-26 AT AT08158752T patent/ATE454886T1/de not_active IP Right Cessation
- 2004-03-26 EP EP08158752A patent/EP1974726B1/en not_active Expired - Lifetime
- 2004-03-26 EP EP09179452.9A patent/EP2186510B1/en not_active Expired - Lifetime
- 2004-03-26 DK DK04723523T patent/DK1610768T3/da active
- 2004-03-26 CA CA2520312A patent/CA2520312C/en not_active Expired - Fee Related
- 2004-03-26 DE DE602004014747T patent/DE602004014747D1/de not_active Expired - Lifetime
- 2004-03-26 WO PCT/DK2004/000217 patent/WO2004084869A1/en not_active Ceased
- 2004-03-26 US US10/550,685 patent/US8298581B2/en not_active Expired - Fee Related
- 2004-03-26 DE DE602004025159T patent/DE602004025159D1/de not_active Expired - Lifetime
- 2004-03-26 JP JP2006504340A patent/JP4989217B2/ja not_active Expired - Fee Related
- 2004-03-26 AT AT04723523T patent/ATE399538T1/de active
- 2004-03-26 EP EP04723523A patent/EP1610768B1/en not_active Expired - Lifetime
- 2004-03-26 ES ES04723523T patent/ES2307003T3/es not_active Expired - Lifetime
-
2009
- 2009-12-18 US US12/642,416 patent/US20100166866A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP2186510A2 (en) | 2010-05-19 |
| EP2186510B1 (en) | 2013-07-10 |
| CA2520312A1 (en) | 2004-10-07 |
| EP1974726A2 (en) | 2008-10-01 |
| US20100166866A1 (en) | 2010-07-01 |
| JP4989217B2 (ja) | 2012-08-01 |
| JP2006521301A (ja) | 2006-09-21 |
| CA2520312C (en) | 2013-06-18 |
| US8298581B2 (en) | 2012-10-30 |
| WO2004084869A1 (en) | 2004-10-07 |
| DE602004025159D1 (de) | 2010-03-04 |
| ES2307003T3 (es) | 2008-11-16 |
| US20070042044A1 (en) | 2007-02-22 |
| ATE399538T1 (de) | 2008-07-15 |
| EP1610768B1 (en) | 2008-07-02 |
| DE602004014747D1 (de) | 2008-08-14 |
| EP1974726B1 (en) | 2010-01-13 |
| EP1610768A1 (en) | 2006-01-04 |
| EP1974726A3 (en) | 2008-11-05 |
| ATE454886T1 (de) | 2010-01-15 |
| EP2186510A3 (en) | 2010-06-09 |
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