DK169335B1 - N-((5R,8S,10R)-2,6-dimethyl-ergolin-8-yl)-2-ethyl-2-methyl-butanamid, fremgangsmåde til fremstilling_deraf, farmaceutiske præparater indeholdende forbindelsen samt anvendelse af forbindelsen som farmaceutikum - Google Patents

N-((5R,8S,10R)-2,6-dimethyl-ergolin-8-yl)-2-ethyl-2-methyl-butanamid, fremgangsmåde til fremstilling_deraf, farmaceutiske præparater indeholdende forbindelsen samt anvendelse af forbindelsen som farmaceutikum Download PDF

Info

Publication number: DK169335B1
Authority: DK; Denmark
Prior art keywords: compound; formula; acid addition; pharmaceutical; addition salt
Prior art date: 1987-06-23

Application number

DK340188A

Other languages

Danish (da)

English (en)

Other versions

DK340188A (da

DK340188D0 (da

Inventor

Walter Haefliger

Original Assignee

Sandoz Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-06-23

Filing date

1988-06-21

Publication date

1994-10-10

1988-06-21 Application filed by Sandoz Ag filed Critical Sandoz Ag

1988-06-21 Publication of DK340188D0 publication Critical patent/DK340188D0/da

1988-12-24 Publication of DK340188A publication Critical patent/DK340188A/da

1994-10-10 Application granted granted Critical

1994-10-10 Publication of DK169335B1 publication Critical patent/DK169335B1/da

Links

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Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/10—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hetero atoms directly attached in position 8
- C07D457/12—Nitrogen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/48—Ergoline derivatives, e.g. lysergic acid, ergotamine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives

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Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Neurology (AREA)
Chemical Kinetics & Catalysis (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
Anesthesiology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Hydrogenated Pyridines (AREA)

DK340188A 1987-06-23 1988-06-21 N-((5R,8S,10R)-2,6-dimethyl-ergolin-8-yl)-2-ethyl-2-methyl-butanamid, fremgangsmåde til fremstilling_deraf, farmaceutiske præparater indeholdende forbindelsen samt anvendelse af forbindelsen som farmaceutikum DK169335B1 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE3720656		1987-06-23
DE3720656		1987-06-23

Publications (3)

Publication Number	Publication Date
DK340188D0 DK340188D0 (da)	1988-06-21
DK340188A DK340188A (da)	1988-12-24
DK169335B1 true DK169335B1 (da)	1994-10-10

Family

ID=6330087

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK340188A DK169335B1 (da)	1987-06-23	1988-06-21	N-((5R,8S,10R)-2,6-dimethyl-ergolin-8-yl)-2-ethyl-2-methyl-butanamid, fremgangsmåde til fremstilling_deraf, farmaceutiske præparater indeholdende forbindelsen samt anvendelse af forbindelsen som farmaceutikum

Country Status (28)

Country	Link
US (1)	US5075318A (es)
JP (1)	JPH0670052B2 (es)
KR (1)	KR970001527B1 (es)
AT (1)	AT395242B (es)
AU (1)	AU615657B2 (es)
BE (1)	BE1004034A3 (es)
CA (1)	CA1302404C (es)
CH (1)	CH674646A5 (es)
CY (1)	CY1752A (es)
DK (1)	DK169335B1 (es)
ES (1)	ES2010282A6 (es)
FI (1)	FI88302C (es)
FR (1)	FR2617166B1 (es)
GB (1)	GB2206115B (es)
GR (1)	GR1002318B (es)
HK (1)	HK2794A (es)
HU (2)	HU203097B (es)
IE (1)	IE60550B1 (es)
IL (1)	IL86820A (es)
IT (1)	IT1219652B (es)
LU (1)	LU87251A1 (es)
MY (1)	MY103584A (es)
NL (1)	NL8801597A (es)
NZ (1)	NZ225112A (es)
PH (1)	PH24690A (es)
PT (1)	PT87781B (es)
SE (1)	SE467925B (es)
ZA (1)	ZA884505B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HU197569B (en) *	1984-01-12	1989-04-28	Sandoz Ag	Process for producing 8alpha-acylaminoergoline derivatives and pharmaceuticals comprising such compounds
JP3630888B2 (ja) *	1996-10-31	2005-03-23	株式会社ニデック	レンズ搬送装置と眼鏡レンズを搬送するための眼鏡レンズ用固定カップ及びレンズ搬送方法
CN102245625A (zh)	2008-10-17	2011-11-16	威斯康星旧生研究基金会	制备有生物活性的α-β肽的方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HU197569B (en) *	1984-01-12	1989-04-28	Sandoz Ag	Process for producing 8alpha-acylaminoergoline derivatives and pharmaceuticals comprising such compounds
NL8503426A (nl) *	1984-12-24	1986-07-16	Sandoz Ag	8alfa-acylamino-ergolinen, werkwijzen voor hun bereiding en farmaceutische preparaten die ze bevatten.

1988
- 1988-06-17 IT IT48097/88A patent/IT1219652B/it active
- 1988-06-20 GB GB8814615A patent/GB2206115B/en not_active Expired - Lifetime
- 1988-06-20 BE BE8800702A patent/BE1004034A3/fr not_active IP Right Cessation
- 1988-06-20 LU LU87251A patent/LU87251A1/fr unknown
- 1988-06-20 FR FR888808357A patent/FR2617166B1/fr not_active Expired - Lifetime
- 1988-06-21 CH CH2387/88A patent/CH674646A5/de not_active IP Right Cessation
- 1988-06-21 DK DK340188A patent/DK169335B1/da not_active IP Right Cessation
- 1988-06-21 GR GR880100401A patent/GR1002318B/el unknown
- 1988-06-21 AU AU18194/88A patent/AU615657B2/en not_active Ceased
- 1988-06-21 HU HU883159A patent/HU203097B/hu not_active IP Right Cessation
- 1988-06-21 NZ NZ225112A patent/NZ225112A/en unknown
- 1988-06-21 SE SE8802323A patent/SE467925B/sv not_active IP Right Cessation
- 1988-06-21 MY MYPI88000682A patent/MY103584A/en unknown
- 1988-06-21 IE IE186788A patent/IE60550B1/en not_active IP Right Cessation
- 1988-06-21 PT PT87781A patent/PT87781B/pt not_active IP Right Cessation
- 1988-06-21 IL IL86820A patent/IL86820A/xx not_active IP Right Cessation
- 1988-06-22 AT AT0161788A patent/AT395242B/de not_active IP Right Cessation
- 1988-06-22 KR KR1019880007511A patent/KR970001527B1/ko not_active Expired - Fee Related
- 1988-06-22 PH PH37103A patent/PH24690A/en unknown
- 1988-06-22 JP JP63154570A patent/JPH0670052B2/ja not_active Expired - Lifetime
- 1988-06-22 FI FI883008A patent/FI88302C/fi not_active IP Right Cessation
- 1988-06-22 CA CA000570102A patent/CA1302404C/en not_active Expired - Lifetime
- 1988-06-23 ZA ZA884505A patent/ZA884505B/xx unknown
- 1988-06-23 ES ES8801948A patent/ES2010282A6/es not_active Expired
- 1988-06-23 NL NL8801597A patent/NL8801597A/nl active Search and Examination
1990
- 1990-11-02 US US07/608,454 patent/US5075318A/en not_active Expired - Lifetime
1994
- 1994-01-13 HK HK27/94A patent/HK2794A/xx not_active IP Right Cessation
- 1994-06-03 CY CY175294A patent/CY1752A/en unknown
1995
- 1995-06-15 HU HU95P/P00209P patent/HU211651A9/hu unknown

Also Published As

Publication number	Publication date
SE8802323D0 (sv)	1988-06-21
GR880100401A (el)	1989-03-08
SE8802323L (sv)	1988-12-24
NZ225112A (en)	1991-03-26
ES2010282A6 (es)	1989-11-01
FI88302B (fi)	1993-01-15
FR2617166B1 (fr)	1992-07-17
FI88302C (fi)	1993-04-26
US5075318A (en)	1991-12-24
JPS6422876A (en)	1989-01-25
ATA161788A (de)	1992-03-15
HUT50174A (en)	1989-12-28
HU211651A9 (en)	1995-12-28
HK2794A (en)	1994-01-21
NL8801597A (nl)	1989-01-16
IL86820A (en)	1991-07-18
GB8814615D0 (en)	1988-07-27
LU87251A1 (fr)	1989-03-08
ZA884505B (en)	1990-02-28
DK340188A (da)	1988-12-24
HU203097B (en)	1991-05-28
GR1002318B (el)	1996-05-13
AT395242B (de)	1992-10-27
FI883008A0 (fi)	1988-06-22
CY1752A (en)	1994-06-03
SE467925B (sv)	1992-10-05
GB2206115A (en)	1988-12-29
MY103584A (en)	1993-08-28
JPH0670052B2 (ja)	1994-09-07
PT87781A (pt)	1989-05-31
AU615657B2 (en)	1991-10-10
KR970001527B1 (ko)	1997-02-11
DK340188D0 (da)	1988-06-21
KR890000479A (ko)	1989-03-14
IL86820A0 (en)	1988-11-30
PH24690A (en)	1990-09-07
CA1302404C (en)	1992-06-02
IE881867L (en)	1988-12-23
IE60550B1 (en)	1994-07-27
PT87781B (pt)	1992-10-30
IT8848097A0 (it)	1988-06-17
AU1819488A (en)	1989-01-05
GB2206115B (en)	1991-04-03
BE1004034A3 (fr)	1992-09-15
CH674646A5 (es)	1990-06-29
FI883008L (fi)	1988-12-24
FR2617166A1 (fr)	1988-12-30
IT1219652B (it)	1990-05-24

Publication	Publication Date	Title
US5177112A (en)	1993-01-05	Substituted 2-aminotetralins
AU655075B2 (en)	1994-12-01	N-alkyl-3-phenyl-3-(2-alkylthiophenoxy)propylamines
CS227019B2 (en)	1984-04-16	Method of preparing (-)-n-methyl-3-(2-methylphenyloxy)-3-phenylpropylamine
HU211575A9 (en)	1995-12-28	2-methyl-thieno-benzodiazepine
PT85628B (pt)	1990-05-31	Processo para a preparacao de derivados de piperidina
KR100417506B1 (ko)	2004-02-05	항우울 치료를 위한 5ｈｔ1 길항제
ES2204154T3 (es)	2004-04-16	Ligandos del receptor 5-ht-1 azabiciclicos.
DK169335B1 (da)	1994-10-10	N-((5R,8S,10R)-2,6-dimethyl-ergolin-8-yl)-2-ethyl-2-methyl-butanamid, fremgangsmåde til fremstilling_deraf, farmaceutiske præparater indeholdende forbindelsen samt anvendelse af forbindelsen som farmaceutikum
IE45149B1 (en)	1982-06-30	Thienopyridines
US5256661A (en)	1993-10-26	Substituted 2-aminotetralins and pharmaceutical use
CS204036B2 (en)	1981-03-31	Method of producing novel 4-phenyl-thieno/2,3-c/piperid
NO865179L (no)	1987-06-22	Fremgangsmaate for fremstilling av optisk aktive 2-klor-12-(3-dimethylamino-2-methylpropyl)-12h-dibenzo(d,g)(1,3,6)dioxazociner.
NO172339B (no)	1993-03-29	Analogifremgangsmaate for fremstilling av terapeutisk aktiv (+)1-((3,4,5-trimetoksy)benzyloksymetyl)-1-fenyl-n,n-dimetyl-n-propylamin
PT86424B (pt)	1990-11-20	Processo para a preparacao de tetra-hidropirido-indoles substituidos
KR100222238B1 (ko)	1999-10-01	스피로 교상 및 비교상 헤테로고리 화합물
FI89796B (fi)	1993-08-13	Oxisalicylamidoderivaters mellanprodukter
CS216651B2 (en)	1982-11-26	Method of making the p-chloracetophenonoxine derivatives
NZ214066A (en)	1988-04-29	3-amino-2,3-dihydro-1-benzoxepine derivatives and pharmaceutical compositions
DK157925B (da)	1990-03-05	2,3,4,5-tetrahydro-1h-3-benzazepinderivater og farmaceutiske praeparater indeholdende disse
PL157529B1 (en)	1992-06-30	Method for manufacturing 8 alfa-acyloaminergoline
MXPA01006669A (es)	2002-03-26	Antagonistas de 5ht1 para terapia antidepresiva
CS266312B2 (cs)	1989-12-13	Způsob výroby benzamidových derivátů

Legal Events

Date	Code	Title	Description
1994-10-10	B1	Patent granted (law 1993)
2001-03-05	PBP	Patent lapsed