DK165119C - Antibiotiske forbindelser betegnet ll-f28249alfa, beta, gamma, delta, epsilon, zeta, eta, theta, iota, kappa, my og ny og pharmaceutisk or pharmakologisk acceptable salte deraf samt fremgangsmaade til deres fremstilling - Google Patents
Antibiotiske forbindelser betegnet ll-f28249alfa, beta, gamma, delta, epsilon, zeta, eta, theta, iota, kappa, my og ny og pharmaceutisk or pharmakologisk acceptable salte deraf samt fremgangsmaade til deres fremstillingInfo
- Publication number
- DK165119C DK165119C DK248885A DK248885A DK165119C DK 165119 C DK165119 C DK 165119C DK 248885 A DK248885 A DK 248885A DK 248885 A DK248885 A DK 248885A DK 165119 C DK165119 C DK 165119C
- Authority
- DK
- Denmark
- Prior art keywords
- f28249alfa
- iota
- zeta
- eta
- kappa
- Prior art date
Links
- 230000003115 biocidal effect Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
- A01N63/20—Bacteria; Substances produced thereby or obtained therefrom
- A01N63/28—Streptomyces
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
- C12P1/06—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using actinomycetales
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/465—Streptomyces
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Dentistry (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- General Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Environmental Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Mycology (AREA)
- Biomedical Technology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Fodder In General (AREA)
- Protection Of Plants (AREA)
- Compounds Of Unknown Constitution (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US61765084A | 1984-06-05 | 1984-06-05 | |
| US61765084 | 1984-06-05 | ||
| US61764984 | 1984-06-05 | ||
| US06/617,649 US4869901A (en) | 1984-06-05 | 1984-06-05 | Method and compositions for helmintic, arthropod ectoparasitic and acaridal infections with novel agents |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| DK248885D0 DK248885D0 (da) | 1985-06-03 |
| DK248885A DK248885A (da) | 1985-12-06 |
| DK165119B DK165119B (da) | 1992-10-12 |
| DK165119C true DK165119C (da) | 1993-03-01 |
Family
ID=27088071
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK248885A DK165119C (da) | 1984-06-05 | 1985-06-03 | Antibiotiske forbindelser betegnet ll-f28249alfa, beta, gamma, delta, epsilon, zeta, eta, theta, iota, kappa, my og ny og pharmaceutisk or pharmakologisk acceptable salte deraf samt fremgangsmaade til deres fremstilling |
| DK051991A DK165461C (da) | 1984-06-05 | 1991-03-22 | Biologisk ren kultur af mikroorganismen streptomyces cyaneogriseus noncyanogenes ll-f28249 med deponeringsnummeret nrrl 15773 |
| DK053591A DK165210C (da) | 1984-06-05 | 1991-03-25 | Fremgangsmaade til bekaempelse af plantenematoder |
| DK053691A DK165436C (da) | 1984-06-05 | 1991-03-25 | Dyrefoder |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK051991A DK165461C (da) | 1984-06-05 | 1991-03-22 | Biologisk ren kultur af mikroorganismen streptomyces cyaneogriseus noncyanogenes ll-f28249 med deponeringsnummeret nrrl 15773 |
| DK053591A DK165210C (da) | 1984-06-05 | 1991-03-25 | Fremgangsmaade til bekaempelse af plantenematoder |
| DK053691A DK165436C (da) | 1984-06-05 | 1991-03-25 | Dyrefoder |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0170006B1 (da) |
| JP (2) | JPH0776223B2 (da) |
| AU (1) | AU588811B2 (da) |
| DE (1) | DE3519834C2 (da) |
| DK (4) | DK165119C (da) |
| ES (1) | ES8703159A1 (da) |
| HU (1) | HU199900B (da) |
| IE (1) | IE58100B1 (da) |
| PT (1) | PT80577B (da) |
Families Citing this family (66)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2858872A (en) * | 1954-09-24 | 1958-11-04 | Everett D Hougen | Means and method for applying tension to sheet metal |
| CH666690A5 (de) * | 1984-09-14 | 1988-08-15 | Glaxo Group Ltd | Antibiotisch wirkende verbindungen der makrolidgruppe aus streptomyces-mikroorganismen, ihre herstellung und verwendung. |
| AR240943A1 (es) * | 1985-02-05 | 1991-03-27 | Sankio Company Limited | Nuevo compuesto agroquimico denominado "sustancia n*51262" procedimiento para prepararlo y composicion que lo comprende" |
| ES8802229A1 (es) * | 1985-04-30 | 1988-04-16 | Glaxo Group Ltd | Un procedimiento para preparar nuevos derivados lactonicos macrociclicos. |
| IE67373B1 (en) * | 1985-09-13 | 1996-03-20 | American Cyanamid Co | Macrolide antibiotics and their preparation |
| GB8606123D0 (en) * | 1986-03-12 | 1986-04-16 | Glaxo Group Ltd | Chemical compounds |
| GB8606108D0 (en) * | 1986-03-12 | 1986-04-16 | Glaxo Group Ltd | Chemical compounds |
| US4918098A (en) * | 1986-03-12 | 1990-04-17 | American Cyanamid Company | Macrolide compounds |
| US5336789A (en) * | 1986-03-12 | 1994-08-09 | American Cyanamid Company | Macrolide compounds |
| DK168866B1 (da) * | 1986-03-12 | 1994-06-27 | American Cyanamid Co | 5-Keto-S541-macrolidforbindelse; krystallinsk produkt indeholdende over 90 % af forbindelsen; præparater indeholdende forbindelsen til anvendelse inden for human- og veterinærmedicin; skadedyrsbekæmpelsespræparat indeholdende forbindelsen; ikke-terapeutisk fremgangsmåde til bekæmpelse af skadedyr under anvendelse af forbindelsen; fremgangsmåde til fremstilling af et fermentationsmedium indeholdend |
| AT398312B (de) * | 1986-03-12 | 1994-11-25 | American Cyanamid Co | Verfahren zur herstellung einer neuen makroliden verbindung |
| GB8606105D0 (en) * | 1986-03-12 | 1986-04-16 | Glaxo Group Ltd | Chemical compounds |
| GB8606122D0 (en) * | 1986-03-12 | 1986-04-16 | Glaxo Group Ltd | Chemical compounds |
| JPH0794457B2 (ja) * | 1986-03-12 | 1995-10-11 | アメリカン・サイアナミツド・カンパニー | マクロライド抗生物質 |
| US5185456A (en) * | 1986-03-12 | 1993-02-09 | American Cyanamid Company | Macrolide compounds |
| AU609032B2 (en) * | 1986-03-12 | 1991-04-26 | American Cyanamid Company | Macrolide compounds |
| ES2054664T3 (es) * | 1986-03-12 | 1994-08-16 | American Cyanamid Co | Compuestos macrolidos. |
| GB8606116D0 (en) * | 1986-03-12 | 1986-04-16 | Glaxo Group Ltd | Process |
| CA1296329C (en) * | 1986-06-06 | 1992-02-25 | Derek R. Sutherland | Macrolide compounds |
| EP0253378A3 (de) * | 1986-07-18 | 1988-03-23 | Ciba-Geigy Ag | 13Beta-Alkyl-derivate von S541-Antibiotika zur Bekämpfung von Parasiten an Nutztieren und Pflanzen |
| EP0254583B1 (en) * | 1986-07-24 | 1994-09-07 | Beecham Group Plc | Parasiticidal milbemycin derivatives, a process for their production, and compositions containing the same |
| US4916154A (en) * | 1986-09-12 | 1990-04-10 | American Cyanamid Company | 23-Imino derivatives of LL-F28249 compounds |
| DE3750355T2 (de) * | 1986-09-12 | 1995-04-06 | American Cyanamid Co | 23-Oxo(keto) und 23-Imino-Derivate von LL-F28249-Verbindungen. |
| US5019589A (en) * | 1986-09-12 | 1991-05-28 | American Cyanamid Company | Δ23 -LL-F28249 compounds |
| US4886828A (en) * | 1986-09-12 | 1989-12-12 | American Cyanamid Company | Δ22 -derivatives of LL-F28249 compounds |
| ES2055695T3 (es) * | 1986-09-12 | 1994-09-01 | American Cyanamid Co | Derivados 23-desoxi de compuestos ll-f28249. |
| US5149832A (en) * | 1986-09-12 | 1992-09-22 | American Cyanamid Company | Mono and diacyl derivatives of ll-f28249 compounds |
| US4831016A (en) * | 1986-10-31 | 1989-05-16 | Merck & Co., Inc. | Reduced avermectin derivatives |
| US4886829A (en) * | 1987-03-06 | 1989-12-12 | American Cyanamid Company | 23-Oxo (keto) and 23-imino derivatives of mono- and diepoxy LL-F28249 compounds |
| US4956479A (en) * | 1987-03-06 | 1990-09-11 | American Cyanamid Company | 23-deoxy-27-chloro derivatives of LL-F28249 compounds |
| US4851428A (en) * | 1987-03-06 | 1989-07-25 | American Cyanamid Company | Mono- and diepoxide derivatives of Δ22-LL-F28249 compounds |
| US4886830A (en) * | 1987-03-06 | 1989-12-12 | American Cyanamid Company | Mono- and diepoxide derivatives of 23-deoxyl-LL-F28249 compounds |
| US4857544A (en) * | 1987-03-06 | 1989-08-15 | American Cyanamid Company | 27-Halo derivatives of LL-F28249 compounds |
| US4806527A (en) * | 1987-03-16 | 1989-02-21 | Merck & Co., Inc. | Avermectin derivatives |
| EP0285561A3 (de) * | 1987-03-27 | 1989-10-25 | Ciba-Geigy Ag | Parasitizide und insektizide Milbemycin-Derivate |
| NZ225364A (en) * | 1987-07-20 | 1990-04-26 | Merck & Co Inc | 5,23-di-hydroxy 25-(4-methyl-hex-2-en-2-yl) milbemycin and parasiticidal compositions |
| JPS6431776A (en) * | 1987-07-28 | 1989-02-02 | Sankyo Co | Novel macrolide compound and production thereof |
| GB8721371D0 (en) * | 1987-09-11 | 1987-10-21 | Glaxo Group Ltd | Chemical compounds |
| GB8721647D0 (en) * | 1987-09-15 | 1987-10-21 | Pfizer Ltd | Antiparasitic agents |
| DE3888936T2 (de) * | 1987-11-03 | 1994-07-21 | Beecham Group Plc | Zwischenprodukte für die Herstellung makrolider Antibiotika mit anthelmintischer Wirkung. |
| GB8804440D0 (en) * | 1988-02-25 | 1988-03-23 | Pfizer Ltd | Antiparasitic agents |
| GB8805978D0 (en) * | 1988-03-14 | 1988-04-13 | Glaxo Group Ltd | Process |
| US5008250A (en) * | 1988-05-25 | 1991-04-16 | Merck & Co., Inc. | Avermectins with a cleaved furan ring and an 8a hydroxy group |
| GB8815967D0 (en) * | 1988-07-05 | 1988-08-10 | Pfizer Ltd | Antiparasitic agents |
| US5428034A (en) * | 1988-09-02 | 1995-06-27 | Sankyo Co., Ltd. | Milbemycin derivatives, their preparation and their use |
| US5015662A (en) * | 1988-10-18 | 1991-05-14 | Merck & Co., Inc. | Anthelmintic bioconversion products |
| NZ232422A (en) * | 1989-02-16 | 1992-11-25 | Merck & Co Inc | 13-ketal milbemycin derivatives and parasiticides |
| ATE103173T1 (de) * | 1989-02-28 | 1994-04-15 | American Cyanamid Co | Bolus mit lang andauernder wirkstoffabgabe, wirksam bei der prophylaxe, behandlung oder bekaempfung des befalls bei wiederkaeuern durch fadenwuermer, milben und endo- und ektoparasiten. |
| GB8917064D0 (en) * | 1989-07-26 | 1989-09-13 | Pfizer Ltd | Antiparasitic agent |
| US5030650A (en) * | 1989-09-11 | 1991-07-09 | American Cyanamid Company | 13-halo-23-imino derivatives of LL-F28249 compounds and their use as endo- and ectoparasiticidal, insecticidal, acaricidal and nematocidal agents |
| US5055454A (en) * | 1989-10-30 | 1991-10-08 | Merck & Co., Inc. | 13-epi-avermectin derivatives useful as antiparasitic agents |
| US5830875A (en) * | 1989-10-30 | 1998-11-03 | Merck & Co., Inc. | 24-and 25-substituted avermectin and milbemycin derivatives |
| JP2622197B2 (ja) * | 1990-03-01 | 1997-06-18 | 三共株式会社 | 13−エーテル置換ミルベマイシン誘導体 |
| US5208222A (en) * | 1991-03-28 | 1993-05-04 | Merck & Co., Inc. | 4"-and 4'-alkylthio avermectin derivatives |
| US5262400A (en) * | 1991-06-20 | 1993-11-16 | Merck & Co., Inc. | 4α-substituted avermectin derivatives |
| GB9205007D0 (en) * | 1992-03-07 | 1992-04-22 | Pfizer Ltd | Antiparasitic agents |
| EP0672114A1 (en) * | 1992-03-13 | 1995-09-20 | Research Corporation Technologies, Inc. | Nematocidal and fungicidal streptomyces dicklowii biopesticide |
| JP2855181B2 (ja) | 1993-12-10 | 1999-02-10 | 敏雄 鈴木 | 松類の枯損防止用組成物及び防止方法 |
| DE69622541T2 (de) * | 1995-03-10 | 2003-03-20 | Takara Shuzo Co., Ltd. | Antibiotika tkr1912-i und tkr1912-ii und verfahren zu ihrer herstellung |
| GB9825402D0 (en) | 1998-11-19 | 1999-01-13 | Pfizer Ltd | Antiparasitic formulations |
| DK1197215T3 (da) | 2000-10-10 | 2006-07-10 | Wyeth Corp | Anthelmintiske sammensætninger |
| IL160619A0 (en) | 2001-09-17 | 2004-07-25 | Lilly Co Eli | Pesticidal formulations pesticidal formulations |
| EP2327410A1 (en) | 2009-10-28 | 2011-06-01 | Consiglio Nazionale Delle Ricerche - Infm Istituto Nazionale Per La Fisica Della Materia | Avermectins and milbemycins for the treatment of flavivirus infections |
| US8980896B2 (en) | 2009-12-17 | 2015-03-17 | Merial, Inc. | Compositions comprising macrocyclic lactone compounds and spirodioxepinoindoles |
| CN103242338B (zh) * | 2013-05-07 | 2015-03-04 | 东北农业大学 | 一种大环内酯类化合物及其制备方法和应用 |
| CN103588784B (zh) * | 2013-11-14 | 2015-12-30 | 大连九信生物化工科技有限公司 | 一种制备高纯度尼莫克汀的方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4378353A (en) * | 1981-02-17 | 1983-03-29 | Merck & Co., Inc. | Novel C-076 compounds |
| US4412991A (en) * | 1981-08-28 | 1983-11-01 | Merck & Co., Inc. | 22-Hydroxy derivatives of C-076 compounds, pharmaceutical compositions and method of use |
| JPS5920285A (ja) * | 1982-07-23 | 1984-02-01 | Sankyo Co Ltd | ミルベマイシンdの5−二塩基酸エステル誘導体及びその塩 |
-
1985
- 1985-06-03 DK DK248885A patent/DK165119C/da not_active IP Right Cessation
- 1985-06-03 PT PT80577A patent/PT80577B/pt unknown
- 1985-06-03 DE DE3519834A patent/DE3519834C2/de not_active Expired - Lifetime
- 1985-06-03 EP EP85106844A patent/EP0170006B1/en not_active Expired - Lifetime
- 1985-06-04 IE IE139185A patent/IE58100B1/en not_active IP Right Cessation
- 1985-06-04 AU AU43283/85A patent/AU588811B2/en not_active Expired
- 1985-06-04 HU HU852207A patent/HU199900B/hu unknown
- 1985-06-05 JP JP60120729A patent/JPH0776223B2/ja not_active Expired - Lifetime
- 1985-06-05 ES ES543948A patent/ES8703159A1/es not_active Expired
-
1991
- 1991-03-22 DK DK051991A patent/DK165461C/da not_active IP Right Cessation
- 1991-03-25 DK DK053591A patent/DK165210C/da not_active IP Right Cessation
- 1991-03-25 DK DK053691A patent/DK165436C/da not_active IP Right Cessation
-
1995
- 1995-01-05 JP JP7015500A patent/JP2524688B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DK165119B (da) | 1992-10-12 |
| DE3519834C2 (de) | 1993-12-16 |
| ES8703159A1 (es) | 1987-02-01 |
| HU199900B (en) | 1990-03-28 |
| DK165210B (da) | 1992-10-26 |
| PT80577B (pt) | 1987-09-18 |
| DE3519834A1 (de) | 1986-03-27 |
| EP0170006B1 (en) | 1992-07-08 |
| DK53691D0 (da) | 1991-03-25 |
| DK53691A (da) | 1991-03-25 |
| DK248885A (da) | 1985-12-06 |
| DK53591D0 (da) | 1991-03-25 |
| IE851391L (en) | 1985-12-05 |
| JPH0776223B2 (ja) | 1995-08-16 |
| PT80577A (en) | 1985-07-01 |
| DK51991A (da) | 1991-03-22 |
| DK53591A (da) | 1991-03-25 |
| DK51991D0 (da) | 1991-03-22 |
| HUT43637A (en) | 1987-11-30 |
| IE58100B1 (en) | 1993-06-30 |
| DK165210C (da) | 1993-03-22 |
| JPS6110589A (ja) | 1986-01-18 |
| DK165436B (da) | 1992-11-30 |
| AU588811B2 (en) | 1989-09-28 |
| EP0170006A2 (en) | 1986-02-05 |
| JP2524688B2 (ja) | 1996-08-14 |
| JPH07233170A (ja) | 1995-09-05 |
| DK165461C (da) | 1993-04-13 |
| DK248885D0 (da) | 1985-06-03 |
| DK165461B (da) | 1992-11-30 |
| EP0170006A3 (en) | 1988-07-20 |
| DK165436C (da) | 1993-04-13 |
| AU4328385A (en) | 1985-12-12 |
| ES543948A0 (es) | 1987-02-01 |
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