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DK157387A - SUBSTITUTED 4-AMINO-3-HYDROXYLIC ACID DERIVATIVES AND PHYSIOLOGICALLY ACCEPTABLE SALTS THEREOF, THEIR PREPARATION AND USE - Google Patents

SUBSTITUTED 4-AMINO-3-HYDROXYLIC ACID DERIVATIVES AND PHYSIOLOGICALLY ACCEPTABLE SALTS THEREOF, THEIR PREPARATION AND USE

Info

Publication number
DK157387A
DK157387A DK157387A DK157387A DK157387A DK 157387 A DK157387 A DK 157387A DK 157387 A DK157387 A DK 157387A DK 157387 A DK157387 A DK 157387A DK 157387 A DK157387 A DK 157387A
Authority
DK
Denmark
Prior art keywords
amino
substituted
preparation
acceptable salts
acid derivatives
Prior art date
Application number
DK157387A
Other languages
Danish (da)
Other versions
DK157387D0 (en
Inventor
Helmut Wegmann
Adalbert Wagner
Heinz-Werner Kleemann
Dieter Ruppert
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of DK157387D0 publication Critical patent/DK157387D0/en
Publication of DK157387A publication Critical patent/DK157387A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0227—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the (partial) peptide sequence -Phe-His-NH-(X)2-C(=0)-, e.g. Renin-inhibitors with n = 2 - 6; for n > 6 see C07K5/06 - C07K5/10

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Pyridine Compounds (AREA)
DK157387A 1986-03-29 1987-03-27 SUBSTITUTED 4-AMINO-3-HYDROXYLIC ACID DERIVATIVES AND PHYSIOLOGICALLY ACCEPTABLE SALTS THEREOF, THEIR PREPARATION AND USE DK157387A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19863610593 DE3610593A1 (en) 1986-03-29 1986-03-29 SUBSTITUTED 4-AMINO-3-HYDROXYBUTTERIC ACID DERIVATIVES METHOD FOR THE PRODUCTION THEREOF, THE CONTAINERS THEREOF AND THEIR USE

Publications (2)

Publication Number Publication Date
DK157387D0 DK157387D0 (en) 1987-03-27
DK157387A true DK157387A (en) 1987-09-30

Family

ID=6297500

Family Applications (1)

Application Number Title Priority Date Filing Date
DK157387A DK157387A (en) 1986-03-29 1987-03-27 SUBSTITUTED 4-AMINO-3-HYDROXYLIC ACID DERIVATIVES AND PHYSIOLOGICALLY ACCEPTABLE SALTS THEREOF, THEIR PREPARATION AND USE

Country Status (5)

Country Link
EP (1) EP0239874A3 (en)
JP (1) JPS62258349A (en)
DE (1) DE3610593A1 (en)
DK (1) DK157387A (en)
PT (1) PT84565B (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2533905B2 (en) * 1987-03-11 1996-09-11 三共株式会社 Peptide derivative having renin inhibitory activity
WO1989004833A1 (en) * 1987-11-16 1989-06-01 The Upjohn Company Renin inhibiting peptides that contain amino and hydroxy dicarboxylic acids
ATE135368T1 (en) * 1989-09-12 1996-03-15 Hoechst Ag AMINO ACID DERIVATIVES WITH RENIN-INHIBITING PROPERTIES, METHOD FOR THE PRODUCTION THEREOF, AGENTS CONTAINING THEM AND THEIR USE
JP2887560B2 (en) * 1994-04-21 1999-04-26 参天製薬株式会社 New sulfur-containing amino acid derivative
EP1265849B1 (en) 2000-03-23 2006-10-25 Elan Pharmaceuticals, Inc. Compounds and methods to treat alzheimer's disease
US6992081B2 (en) 2000-03-23 2006-01-31 Elan Pharmaceuticals, Inc. Compounds to treat Alzheimer's disease
PE20020276A1 (en) 2000-06-30 2002-04-06 Elan Pharm Inc SUBSTITUTE AMINE COMPOUNDS AS ß-SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER
US6846813B2 (en) 2000-06-30 2005-01-25 Pharmacia & Upjohn Company Compounds to treat alzheimer's disease
CA2410972A1 (en) 2000-06-30 2002-01-10 Elan Pharmaceuticals, Inc. Compounds to treat alzheimer's disease
BR0210721A (en) 2001-06-27 2004-07-20 Elan Pharm Inc Pharmaceutically acceptable compound, salt or ester, method for making a compound, and method for treating a patient having, or preventing the patient from acquiring a disease or condition.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK110285A (en) * 1984-03-12 1985-09-13 Pfizer POLYPEPTIDES AND POLYPEPTIDE DERIVATIVES CONTAINING STATIN OR DERIVATIVES THEREOF AND PHARMACEUTICAL PREPARATIONS
EP0163237A3 (en) * 1984-05-29 1988-04-27 Merck & Co. Inc. Di- and tri-peptidal renin inhibitors
EP0173481A3 (en) * 1984-08-06 1988-12-21 The Upjohn Company Peptides
SU1676454A3 (en) * 1984-11-30 1991-09-07 Санкио Компани Лимитед (Фирма) Method for peptides preparation of theirs pharmaceutically accessible salts
DE3601248A1 (en) * 1986-01-17 1987-07-23 Hoechst Ag SUBSTITUTED 4-AMINO-3-HYDROXYBUTTERIC ACID DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, THESE AGENTS AND THEIR USE

Also Published As

Publication number Publication date
DK157387D0 (en) 1987-03-27
JPS62258349A (en) 1987-11-10
PT84565A (en) 1987-04-01
DE3610593A1 (en) 1987-10-01
PT84565B (en) 1989-11-10
EP0239874A2 (en) 1987-10-07
EP0239874A3 (en) 1989-08-30

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