DK146342C - Fremgangsmaade til fremstilling af anthracyclinglycosidantibiotika betegnet ma 144-m1 og ma 144-m2 eller ikke toksiske syreadditionssalte eller komplekser deraf med desoxyribonucleinsyre - Google Patents

Fremgangsmaade til fremstilling af anthracyclinglycosidantibiotika betegnet ma 144-m1 og ma 144-m2 eller ikke toksiske syreadditionssalte eller komplekser deraf med desoxyribonucleinsyre

Info

Publication number: DK146342C
Authority: DK; Denmark
Prior art keywords: lycosid; anthracycling; complexes; preparing; addition salts
Prior art date: 1976-04-07

Application number

DK152977A

Other languages

English (en)

Other versions

DK146342B (da

DK152977A (da

Inventor

Hamao Umezawa

Tomio Takeuchi

Hiroshi Naganawa

Masaaki Ishizuka

Norio Shibamoto

Toshikazu Oki

Taiji Inui

Original Assignee

Microbial Chem Res Found

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-04-07

Filing date

1977-04-05

Publication date

1984-04-09

1977-04-05 Application filed by Microbial Chem Res Found filed Critical Microbial Chem Res Found

1977-10-08 Publication of DK152977A publication Critical patent/DK152977A/da

1983-09-12 Publication of DK146342B publication Critical patent/DK146342B/da

1984-04-09 Application granted granted Critical

1984-04-09 Publication of DK146342C publication Critical patent/DK146342C/da

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/56—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound to a condensed ring system having three or more carbocyclic rings, e.g. daunomycin, adriamycin
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/465—Streptomyces
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/465—Streptomyces
- C12R2001/48—Streptomyces antibioticus ; Actinomyces antibioticus
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/886—Streptomyces
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/886—Streptomyces
- Y10S435/888—Streptomyces antibioticus

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Biotechnology (AREA)
Genetics & Genomics (AREA)
General Health & Medical Sciences (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Bioinformatics & Cheminformatics (AREA)
Biochemistry (AREA)
Medicinal Chemistry (AREA)
General Engineering & Computer Science (AREA)
Microbiology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Molecular Biology (AREA)
Biomedical Technology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Virology (AREA)
Tropical Medicine & Parasitology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Saccharide Compounds (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

DK152977A 1976-04-07 1977-04-05 Fremgangsmaade til fremstilling af anthracyclinglycosidantibiotika betegnet ma 144-m1 og ma 144-m2 eller ikke toksiske syreadditionssalte eller komplekser deraf med desoxyribonucleinsyre DK146342C (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP3968876A JPS52136159A (en)	1976-04-07	1976-04-07	Anti/malignanttumor containing the same as active ingredients
JP3968876		1976-04-07

Publications (3)

Publication Number	Publication Date
DK152977A DK152977A (da)	1977-10-08
DK146342B DK146342B (da)	1983-09-12
DK146342C true DK146342C (da)	1984-04-09

Family

ID=12559990

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK152977A DK146342C (da)	1976-04-07	1977-04-05	Fremgangsmaade til fremstilling af anthracyclinglycosidantibiotika betegnet ma 144-m1 og ma 144-m2 eller ikke toksiske syreadditionssalte eller komplekser deraf med desoxyribonucleinsyre

Country Status (11)

Country	Link
US (2)	US4144329A (da)
JP (1)	JPS52136159A (da)
BE (1)	BE853203A (da)
CA (1)	CA1097238A (da)
DE (1)	DE2715255C3 (da)
DK (1)	DK146342C (da)
ES (3)	ES475579A1 (da)
FR (1)	FR2347381A1 (da)
GB (1)	GB1563432A (da)
NL (1)	NL168557C (da)
SE (1)	SE436758B (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4123608A (en) *	1977-07-18	1978-10-31	Bristol-Myers Company	Antibiotic compound
IL60094A0 (en) *	1979-05-22	1980-07-31	Sparamedica Ag	Tetracyclic compounds,their preparation and pharmaceutical compositions containing them
JPS6023679B2 (ja) *	1979-07-13	1985-06-08	メルシャン株式会社	ロドマイシン群抗生物質とその製造法
EP0030255B1 (en) *	1979-09-07	1986-01-29	Sanraku Incorporated	2-hydroxyaclacinomycin a, pharmaceutical composition containing it; 2-hydroxyaclavinone and fermentative process for preparing same
JPS5767518A (en) *	1980-09-17	1982-04-24	Yamasa Shoyu Co Ltd	Radiosensitizing agent or agent for increasing effect of radiomimetic substance
CH648327A5 (de) *	1980-10-16	1985-03-15	Hoffmann La Roche	Anthracycline.
CA1187434A (en) *	1981-08-11	1985-05-21	Akihiro Yoshimoto	Anthracycline antibiotics and their preparation method
JPS6133194A (ja) *	1984-07-25	1986-02-17	Sanraku Inc	新規アントラサイクリン抗生物質
US20050208037A1 (en) *	2003-10-21	2005-09-22	Board Of Regents, The University Of Texas System	Thioredoxin increases redox-cycling of anticancer agents thereby sensitizes cancer cells to apoptosis
CN104644631A (zh) *	2015-01-31	2015-05-27	云南省第一人民医院	新乌头碱对k562细胞生物学特性的改变

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB846130A (en)	1956-03-23	1960-08-24	Ciba Ltd	New antibiotic and derivatives and salts thereof, preparations containing the same and process for the manufacture of these substances
US3864480A (en) *	1974-05-06	1975-02-04	Merck & Co Inc	Cinerubin A and B As Antiparasitic Agents
JPS5134915B2 (da) *	1974-07-27	1976-09-29
JPS5323961A (en) *	1976-08-16	1978-03-06	Microbial Chem Res Found	Antitumors

1976
- 1976-04-07 JP JP3968876A patent/JPS52136159A/ja active Granted
1977
- 1977-03-24 US US05/780,730 patent/US4144329A/en not_active Expired - Lifetime
- 1977-03-31 SE SE7703760A patent/SE436758B/xx not_active IP Right Cessation
- 1977-03-31 FR FR7709758A patent/FR2347381A1/fr active Granted
- 1977-04-04 BE BE176386A patent/BE853203A/xx not_active IP Right Cessation
- 1977-04-05 NL NLAANVRAGE7703753,A patent/NL168557C/xx not_active IP Right Cessation
- 1977-04-05 ES ES475579A patent/ES475579A1/es not_active Expired
- 1977-04-05 DK DK152977A patent/DK146342C/da not_active IP Right Cessation
- 1977-04-05 DE DE2715255A patent/DE2715255C3/de not_active Expired
- 1977-04-05 GB GB14434/77A patent/GB1563432A/en not_active Expired
- 1977-04-05 CA CA275,564A patent/CA1097238A/en not_active Expired
1978
- 1978-05-03 ES ES469423A patent/ES469423A1/es not_active Expired
- 1978-05-03 ES ES469424A patent/ES469424A1/es not_active Expired
1979
- 1979-03-05 US US06/017,525 patent/US4219622A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
NL168557C (nl)	1982-04-16
DE2715255A1 (de)	1977-11-10
ES469423A1 (es)	1979-04-01
US4219622A (en)	1980-08-26
US4144329A (en)	1979-03-13
FR2347381A1 (fr)	1977-11-04
JPS5438100B2 (da)	1979-11-19
JPS52136159A (en)	1977-11-14
GB1563432A (en)	1980-03-26
SE7703760L (sv)	1977-10-08
BE853203A (fr)	1977-08-01
SE436758B (sv)	1985-01-21
CA1097238A (en)	1981-03-10
DE2715255B2 (de)	1979-01-04
DK146342B (da)	1983-09-12
FR2347381B1 (da)	1980-10-17
ES475579A1 (es)	1978-08-01
ES469424A1 (es)	1979-04-01
NL7703753A (nl)	1977-10-11
DK152977A (da)	1977-10-08
DE2715255C3 (de)	1979-08-30

Publication	Publication Date	Title
NL185459C (nl)	1990-04-17	Werkwijze ter bereiding van hardbare materialen en voorwerpen daaruit.
DK6177A (da)	1977-07-09	Foretherede hydroxy-benzodiheterocycler eller salte deraf og fremgangsmade til fremstilling deraf
NL7706301A (nl)	1977-12-23	Farmaceutisch inbrengpreparaat en werkwijze ter bereiding daarvan.
NL7502843A (nl)	1975-09-16	Anti-transpiratiemiddel en werkwijze ter berei- ding daarvan.
DK150512C (da)	1987-11-16	Analogifremgangsmaade til fremstilling af 3-quino-lincarboxylsyrederivater eller syreadditionssalte deraf
DK471479A (da)	1980-06-14	Fremgangsmaade til fremstilling af imidazolderivater og salte deraf
NL7712750A (nl)	1978-05-23	1-carba-2-penem-3-carbonzuur en derivaten.
DK149586C (da)	1987-01-05	Fremgangsmaade til fremstilling af 1-amino-cyclopropan-carboxylsyre og derivater deraf
DK146342C (da)	1984-04-09	Fremgangsmaade til fremstilling af anthracyclinglycosidantibiotika betegnet ma 144-m1 og ma 144-m2 eller ikke toksiske syreadditionssalte eller komplekser deraf med desoxyribonucleinsyre
NL7702419A (nl)	1977-09-12	Copolyamiden en werkwijze ter bereiding daarvan.
DK496977A (da)	1978-05-10	Fremgangsmaade til fremstilling af 0-alkylerede hydroxylaminer og syreadditionssalte deraf
HU173105B (hu)	1979-02-28	Sposob poluchenija 1-nitro-9-dialkilamino-izoalkilamino-akridinov i ikh solej
SE437969B (sv)	1985-03-25	Forpackning med vik- eller fellock
NO150559C (no)	1984-11-07	4-halogen-dihydropyran-forbindelser og fremgangsmaate for fremstilling derav
DK144526C (da)	1982-10-04	Herbicide 3-alkylisoxazolderivater og salte deraf
FI803660A7 (fi)	1981-05-27	Menetelmä kalvojen ja päällysteiden valmistamiseksi.
NO1994024I1 (no)	1994-11-25	Romifidin/ 2-brom-6-fluor-N-2-imidazolidinyliden-benzamin og syreaddisjonssalter derav
DK281377A (da)	1977-12-26	Joderede isophthalamsyrederivater og fremgangsmade til fremstilling deraf
NO150761C (no)	1984-12-12	3,4-dihydro-2-metyl-4-okso-2h-1,2-benzotiazin-3-karboksylsyre-1,1-dioksyd og fremgangsmaate for fremstilling derav
DK138427B (da)	1978-09-04	Analogifremgangsmåde til fremstilling af amider af apovincamin- og desoxyvincaminsyre eller syreadditionssalte heraf.
BE825684A (nl)	1975-08-19	N-carbamoyloxypyridiniumzouten en werkwijze voor het bereiding daarvan
DK284977A (da)	1977-12-29	Fremgangsmade til fremstilling af cephemderivater
NO156564C (no)	1987-10-14	Kompleks-salter og fremgangsmaate til fremstilling derav.
DK153377A (da)	1977-10-08	Fremgangsmade til fremstilling af cephemderivater
NL7602646A (nl)	1976-09-16	13.14-dehydro-11-deoxyprostaglandinen en werk- wijze ter bereiding ervan.

Legal Events

Date	Code	Title	Description
1988-03-07	PBP	Patent lapsed
1999-03-15	PBP	Patent lapsed