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DK146005C - METHOD OF ANALOGUE FOR THE PREPARATION OF ALKYLTHIOPHENOXYPROPANOLAMINES OR ACID ADDITION SALTS THEREOF - Google Patents

METHOD OF ANALOGUE FOR THE PREPARATION OF ALKYLTHIOPHENOXYPROPANOLAMINES OR ACID ADDITION SALTS THEREOF

Info

Publication number
DK146005C
DK146005C DK450978A DK450978A DK146005C DK 146005 C DK146005 C DK 146005C DK 450978 A DK450978 A DK 450978A DK 450978 A DK450978 A DK 450978A DK 146005 C DK146005 C DK 146005C
Authority
DK
Denmark
Prior art keywords
alkylthiophenoxypropanolamines
analogue
preparation
acid addition
addition salts
Prior art date
Application number
DK450978A
Other languages
Danish (da)
Other versions
DK450978A (en
DK146005B (en
Inventor
Duane F Morrow
William L Matier
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of DK450978A publication Critical patent/DK450978A/en
Publication of DK146005B publication Critical patent/DK146005B/en
Application granted granted Critical
Publication of DK146005C publication Critical patent/DK146005C/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/31Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
    • C07C323/32Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton having at least one of the nitrogen atoms bound to an acyclic carbon atom of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/12Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK450978A 1977-10-11 1978-10-10 METHOD OF ANALOGUE FOR THE PREPARATION OF ALKYLTHIOPHENOXYPROPANOLAMINES OR ACID ADDITION SALTS THEREOF DK146005C (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US84116877A 1977-10-11 1977-10-11
US84116877 1977-10-11
US94222278A 1978-09-14 1978-09-14
US94222278 1978-09-14

Publications (3)

Publication Number Publication Date
DK450978A DK450978A (en) 1979-04-12
DK146005B DK146005B (en) 1983-05-16
DK146005C true DK146005C (en) 1989-05-29

Family

ID=27126241

Family Applications (1)

Application Number Title Priority Date Filing Date
DK450978A DK146005C (en) 1977-10-11 1978-10-10 METHOD OF ANALOGUE FOR THE PREPARATION OF ALKYLTHIOPHENOXYPROPANOLAMINES OR ACID ADDITION SALTS THEREOF

Country Status (21)

Country Link
JP (1) JPS6049188B2 (en)
AR (2) AR224239A1 (en)
AU (1) AU520181B2 (en)
CA (1) CA1116636A (en)
CH (1) CH642349A5 (en)
DE (1) DE2844353C2 (en)
DK (1) DK146005C (en)
ES (1) ES474156A1 (en)
FI (1) FI70883C (en)
FR (1) FR2405932A1 (en)
GB (1) GB2006197B (en)
GR (1) GR73919B (en)
IE (1) IE47449B1 (en)
IL (1) IL55695A (en)
IT (1) IT1109310B (en)
LU (1) LU80345A1 (en)
NL (1) NL7810156A (en)
NO (1) NO146161C (en)
PH (1) PH15824A (en)
SE (1) SE443782B (en)
YU (1) YU41602B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4396629A (en) 1980-12-29 1983-08-02 Sterling Drug Inc. Compositions, processes and method

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL6504268A (en) * 1965-04-03 1966-10-04
DE2551141A1 (en) * 1975-11-14 1977-05-18 Dolorgiet Arzneimittelfabrik (1)-Cyclododecylamino'(2)-hydroxy-propane derivs. - selective beta-receptor blockers
DE2552266A1 (en) * 1975-11-21 1977-05-26 Dolorgiet Arzneimittelfabrik (1)-Aryloxy or arylthio-(3)-cyclohexylamino-(2)-propanol derivs. - prepd. e.g. by reacting epoxy propane cpds. with (3,3,5)-trimethyl-cyclohexylamine

Also Published As

Publication number Publication date
PH15824A (en) 1983-04-08
NO146161C (en) 1982-08-11
ES474156A1 (en) 1979-10-16
AU520181B2 (en) 1982-01-21
GB2006197A (en) 1979-05-02
FR2405932A1 (en) 1979-05-11
DK450978A (en) 1979-04-12
SE7810574L (en) 1979-04-12
IE47449B1 (en) 1984-03-21
GR73919B (en) 1984-05-22
FR2405932B1 (en) 1981-03-20
YU41602B (en) 1987-12-31
AR223016A1 (en) 1981-07-15
JPS5488232A (en) 1979-07-13
DE2844353A1 (en) 1979-04-19
IE782018L (en) 1979-04-11
GB2006197B (en) 1982-01-27
CA1116636A (en) 1982-01-19
AR224239A1 (en) 1981-11-13
FI783068A7 (en) 1979-04-12
FI70883B (en) 1986-07-18
AU4039378A (en) 1980-04-17
DE2844353C2 (en) 1984-01-26
NO146161B (en) 1982-05-03
LU80345A1 (en) 1979-06-15
IT1109310B (en) 1985-12-16
JPS6049188B2 (en) 1985-10-31
DK146005B (en) 1983-05-16
FI70883C (en) 1986-10-27
SE443782B (en) 1986-03-10
CH642349A5 (en) 1984-04-13
IT7851437A0 (en) 1978-10-10
YU235278A (en) 1983-01-21
NL7810156A (en) 1979-04-17
NO783416L (en) 1979-05-25
IL55695A0 (en) 1978-12-17
IL55695A (en) 1982-01-31

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