[go: up one dir, main page]

DK1308168T3 - Nye lægemidler mod cancer - Google Patents

Nye lægemidler mod cancer

Info

Publication number
DK1308168T3
DK1308168T3 DK01954360T DK01954360T DK1308168T3 DK 1308168 T3 DK1308168 T3 DK 1308168T3 DK 01954360 T DK01954360 T DK 01954360T DK 01954360 T DK01954360 T DK 01954360T DK 1308168 T3 DK1308168 T3 DK 1308168T3
Authority
DK
Denmark
Prior art keywords
cancer drugs
new anti
medicament
pharmaceutically acceptable
acceptable salt
Prior art date
Application number
DK01954360T
Other languages
English (en)
Inventor
Toshihiro Noguchi
Akemi Baba
Mitsuharu Hanada
Original Assignee
Dainippon Sumitomo Pharma Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dainippon Sumitomo Pharma Co filed Critical Dainippon Sumitomo Pharma Co
Application granted granted Critical
Publication of DK1308168T3 publication Critical patent/DK1308168T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/7036Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
DK01954360T 2000-07-28 2001-07-26 Nye lægemidler mod cancer DK1308168T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2000228239 2000-07-28
PCT/JP2001/006467 WO2002009754A1 (en) 2000-07-28 2001-07-26 Novel remedies for cancer

Publications (1)

Publication Number Publication Date
DK1308168T3 true DK1308168T3 (da) 2008-07-28

Family

ID=18721568

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01954360T DK1308168T3 (da) 2000-07-28 2001-07-26 Nye lægemidler mod cancer

Country Status (13)

Country Link
US (3) US7449181B2 (da)
EP (1) EP1308168B1 (da)
JP (1) JP5117660B2 (da)
KR (1) KR20030019623A (da)
CN (2) CN100581585C (da)
AT (1) ATE397458T1 (da)
AU (1) AU2001276689A1 (da)
CA (1) CA2417255C (da)
DE (1) DE60134324D1 (da)
DK (1) DK1308168T3 (da)
ES (1) ES2307633T3 (da)
TW (1) TWI317285B (da)
WO (1) WO2002009754A1 (da)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7393823B1 (en) 1999-01-20 2008-07-01 Oregon Health And Science University HER-2 binding antagonists
US7625859B1 (en) * 2000-02-16 2009-12-01 Oregon Health & Science University HER-2 binding antagonists
NZ522444A (en) * 2000-05-19 2004-09-24 Genentech Inc Gene detection assay for improving the likelihood of an effective response to an ErbB antagonist cancer therapy
KR100978705B1 (ko) * 2002-03-18 2010-08-30 다이닛본 스미토모 세이야꾸 가부시끼가이샤 폐암 치료
FR2844455B1 (fr) * 2002-09-13 2007-12-14 Lab Francais Du Fractionnement Traitement des pathologies echappant a la reponse immune par des anticorps optimises
WO2006042002A2 (en) * 2004-10-05 2006-04-20 Oregon Health And Science University Compositions and methods for treating disease
CN100464783C (zh) * 2004-11-22 2009-03-04 山东蓝金生物工程有限公司 一种含抗肿瘤抗生素的抗癌药物组合物
BRPI0518104B8 (pt) 2005-01-21 2021-05-25 Genentech Inc artigo industrializado e uso de anticorpo her2
RU2404806C2 (ru) * 2005-02-23 2010-11-27 Дженентек, Инк. Продление времени до прогрессирования заболевания или продолжительности жизни у онкологических больных с применением ингибиторов димеризации her
TW200642695A (en) * 2005-03-08 2006-12-16 Genentech Inc Methods for identifying tumors responsive to treatment with her dimerization inhibitors (HDIs)
JP2006316040A (ja) 2005-05-13 2006-11-24 Genentech Inc Herceptin(登録商標)補助療法
CA2677108A1 (en) 2007-03-02 2008-09-12 Genentech, Inc. Predicting response to a her inhibitor
WO2008154249A2 (en) 2007-06-08 2008-12-18 Genentech, Inc. Gene expression markers of tumor resistance to her2 inhibitor treatment
US9551033B2 (en) * 2007-06-08 2017-01-24 Genentech, Inc. Gene expression markers of tumor resistance to HER2 inhibitor treatment
BRPI0812682A2 (pt) 2008-06-16 2010-06-22 Genentech Inc tratamento de cáncer de mama metastático
EP2362783A2 (en) 2008-10-31 2011-09-07 Biogen Idec MA Inc. Light targeting molecules and uses thereof
EP2408817B1 (en) 2009-03-20 2016-03-16 F.Hoffmann-La Roche Ag Bispecific anti-her antibodies
US20120121586A1 (en) 2009-05-29 2012-05-17 Astrid Kiermaier Modulators for her2 signaling in her2 expressing patients with gastric cancer
SG183333A1 (en) 2010-02-18 2012-09-27 Genentech Inc Neuregulin antagonists and use thereof in treating cancer
WO2011146568A1 (en) 2010-05-19 2011-11-24 Genentech, Inc. Predicting response to a her inhibitor
EP2643353A1 (en) 2010-11-24 2013-10-02 Novartis AG Multispecific molecules
JP5766296B2 (ja) 2010-12-23 2015-08-19 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft ポリペプチド−ポリヌクレオチド複合体、およびエフェクター成分の標的化された送達におけるその使用
CA2842375A1 (en) 2011-08-17 2013-02-21 Erica Jackson Neuregulin antibodies and uses thereof
WO2013063229A1 (en) 2011-10-25 2013-05-02 The Regents Of The University Of Michigan Her2 targeting agent treatment in non-her2-amplified cancers having her2 expressing cancer stem cells
CA2857114A1 (en) 2011-11-30 2013-06-06 Genentech, Inc. Erbb3 mutations in cancer
EP2788500A1 (en) 2011-12-09 2014-10-15 F.Hoffmann-La Roche Ag Identification of non-responders to her2 inhibitors
CN104220457A (zh) 2012-03-27 2014-12-17 霍夫曼-拉罗奇有限公司 涉及her3抑制剂的诊断和治疗
EP3511718A1 (en) 2012-11-30 2019-07-17 F. Hoffmann-La Roche AG Pd-l1 inhibitor
US20190151346A1 (en) 2016-05-10 2019-05-23 INSERM (Institute National de la Santé et de la Recherche Médicale) Combinations therapies for the treatment of cancer
CN107349426B (zh) * 2017-07-12 2018-03-23 马骥 阿司匹林与曲妥珠单抗联合或协同在肿瘤治疗中的应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6075473A (ja) 1983-09-30 1985-04-27 Sumitomo Chem Co Ltd アミノナフタセン誘導体
US5185432A (en) * 1986-02-26 1993-02-09 Oncogen Monoclonal antibodies and antigen for human non-small cell lung carcinoma and other certain human carcinomas
JP3040121B2 (ja) * 1988-01-12 2000-05-08 ジェネンテク,インコーポレイテッド 増殖因子レセプターの機能を阻害することにより腫瘍細胞を処置する方法
US5077220A (en) * 1988-08-26 1991-12-31 John Muir Cancer & Aging Institute Monoclonal antibody specific to a novel glycoprotein antigen on human carcinoma cells
JPH035397A (ja) 1989-05-31 1991-01-11 Toshiba Corp 酸化物結晶薄膜の気相成長方法
JP3005397B2 (ja) 1993-09-06 2000-01-31 関西日本電気ソフトウェア株式会社 デッドロック多発自動回避方式
US5686278A (en) * 1994-03-25 1997-11-11 Indiana University Foundation Methods for enhanced retrovirus-mediated gene transfer
CN1164238A (zh) * 1994-09-12 1997-11-05 国际生物免疫有限公司 抗人结肠癌相关抗原的单克隆抗体及其应用
BR9707495A (pt) * 1996-02-13 1999-07-27 Zeneca Ltd Derivado de quinazolina processo para a preparação do mesmo composição farmacêutica e processo para a produç o de um efeito antiangiogênico e/ou de redução de permeabilidade vascular em um animal de sangue quente
CN1082187C (zh) * 1996-11-26 2002-04-03 北京市肿瘤防治研究所 一种检测雌激素受体水平的生物试剂及免疫组化方法
CN100333796C (zh) * 1997-01-22 2007-08-29 德克萨斯州立大学董事会 凝血和肿瘤治疗的组织因子及其组合物
US20030068318A1 (en) * 2001-09-28 2003-04-10 O'brien Timothy Treatment of uterine serous papillary cancer

Also Published As

Publication number Publication date
AU2001276689A1 (en) 2002-02-13
US9139658B2 (en) 2015-09-22
CN101732333B (zh) 2012-08-15
EP1308168A1 (en) 2003-05-07
US20080031881A1 (en) 2008-02-07
KR20030019623A (ko) 2003-03-06
CN100581585C (zh) 2010-01-20
CA2417255C (en) 2011-08-02
EP1308168B1 (en) 2008-06-04
US20030157097A1 (en) 2003-08-21
TWI317285B (en) 2009-11-21
EP1308168A4 (en) 2004-09-01
US20110104160A1 (en) 2011-05-05
ATE397458T1 (de) 2008-06-15
CN1466464A (zh) 2004-01-07
DE60134324D1 (de) 2008-07-17
CN101732333A (zh) 2010-06-16
ES2307633T3 (es) 2008-12-01
US7449181B2 (en) 2008-11-11
WO2002009754A1 (en) 2002-02-07
CA2417255A1 (en) 2003-01-24
JP5117660B2 (ja) 2013-01-16
US7879327B2 (en) 2011-02-01

Similar Documents

Publication Publication Date Title
DK1308168T3 (da) Nye lægemidler mod cancer
BR0311443A (pt) Método e dispositivo para controlar farmacocinética de droga
DE602004027936D1 (de) Tocopherolmodifizierte therapeutische arzneimittelverbindung
NO20053224D0 (no) Patient controlled drug administration device.
AR027355A1 (es) Acidos tiazolidincarboxilicos
HU0102039D0 (en) Use of paclitaxel stabilized with albumin for the preparation of pharmaceutical compositions treating solid tumors and the pharmaceutical compositions obtained thereby
IT1317735B1 (it) Sali di agenti antimicrobici.
ITTO20001224A0 (it) Dispositivo portatile per infusione di farmaci.
CY1112473T1 (el) Μεθοδοι θεραπειας για καρκινους σχετιζομενους με β κυτταρα
NO20032027L (no) Effektive antitumorbehandlinger
UY27455A1 (es) Derivados n-(1,4,5,6-tetrahidro-ciclopentapirazol -3-il)- sustituidos. su obtención y uso como fármacos.
EP1379508A4 (en) N- (ARYL) -2-ARYLETHESULFONAMIDES AND THEIR THERAPEUTIC APPLICATIONS
DE60102590D1 (de) Darreichungsformen zur behandlung von oralen mykosen
BR0008402A (pt) Usos de doxepina, cloridreto de doxepina ou um metabólito de doxepina ou cloridreto de doxepina, e de um tca, composição farmacêutica, métodos para prover um tratamento analgésico, e para melhorar a dor profunda localizada ou interna
EP1453507A4 (en) SOLUBILIZED TOPOISOMERASE GIFT MEDIUM
ITTO991129A0 (it) Siringa per infusione di farmaci.
NO20031410L (no) Anvendelse av distamycinderivater for fremstilling av medikamenter
HRP20080597T3 (en) Cancer combination therapy comprising azd2171 and zd1839
RU2000102259A (ru) Способ лечения хламидийного конъюнктивита
AR109456A2 (es) Uso de et743 para la preparación de un medicamento para el tratamiento de un paciente humano afectado por cáncer mediante terapia de combinación
DE60214412D1 (de) Simplifizierte sarcodictyn-derivate als anti-tumor-mittel
RU99118112A (ru) Способ лечения больных с невротическими расстройствами препаратом "миелопид"
AR033579A1 (es) Terapia antitumoral que comprende derivados de distamicina
RU2000110690A (ru) Способ антибиотикотерапии
UA3848U (uk) Спосіб активації процесів метаболізму у високопродуктивних корів