DK139814B - Analogous process for the preparation of locally anesthetically active 2-alkyl-2- (dialkylamino- or pyrrolidino) -2 ', 6'-acetoxylidides in optically active or racemic form or pharmaceutically acceptable salts thereof. - Google Patents

Analogous process for the preparation of locally anesthetically active 2-alkyl-2- (dialkylamino- or pyrrolidino) -2 ', 6'-acetoxylidides in optically active or racemic form or pharmaceutically acceptable salts thereof.

Info

Publication number: DK139814B
Authority: DK; Denmark
Prior art keywords: active; acetoxylidides; pyrrolidino; dialkylamino; alkyl
Prior art date: 1970-12-22

Application number

DK619771AA

Other languages

Danish (da)

Other versions

DK139814C (en

Inventor

Herbert J F Adams

George H Kronberg

Bertil H Takman

Original Assignee

Astra Pharma Prod

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1970-12-22

Filing date

1971-12-17

Publication date

1979-04-23

1971-12-17 Application filed by Astra Pharma Prod filed Critical Astra Pharma Prod

1979-04-23 Publication of DK139814B publication Critical patent/DK139814B/en

1979-10-01 Application granted granted Critical

1979-10-01 Publication of DK139814C publication Critical patent/DK139814C/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
- C07C53/38—Acyl halides
- C07C53/46—Acyl halides containing halogen outside the carbonyl halide group
- C07C53/50—Acyl halides containing halogen outside the carbonyl halide group of acids containing three or more carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyridine Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

DK619771AA 1970-12-22 1971-12-17 Analogous process for the preparation of locally anesthetically active 2-alkyl-2- (dialkylamino- or pyrrolidino) -2 ', 6'-acetoxylidides in optically active or racemic form or pharmaceutically acceptable salts thereof. DK139814B (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US10077770A	1970-12-22	1970-12-22
US00164022A US3812147A (en)	1970-12-22	1971-07-19	Acylxylidide local anaesthetics

Publications (2)

Publication Number	Publication Date
DK139814B true DK139814B (en)	1979-04-23
DK139814C DK139814C (en)	1979-10-01

Family

ID=26797539

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK619771AA DK139814B (en)	1970-12-22	1971-12-17	Analogous process for the preparation of locally anesthetically active 2-alkyl-2- (dialkylamino- or pyrrolidino) -2 ', 6'-acetoxylidides in optically active or racemic form or pharmaceutically acceptable salts thereof.

Country Status (23)

Country	Link
US (1)	US3812147A (en)
JP (1)	JPS5644063B1 (en)
AR (1)	AR193840A1 (en)
AT (1)	AT319205B (en)
AU (1)	AU468489B2 (en)
BE (1)	BE776656A (en)
BR (1)	BR7108466D0 (en)
CA (1)	CA943966A (en)
DD (1)	DD99779A5 (en)
DE (1)	DE2162744C3 (en)
DK (1)	DK139814B (en)
ES (2)	ES398210A1 (en)
FI (1)	FI55027C (en)
FR (1)	FR2118985B1 (en)
GB (1)	GB1369259A (en)
HU (1)	HU163373B (en)
IE (1)	IE35909B1 (en)
IT (1)	IT1066334B (en)
NL (2)	NL172149C (en)
NO (1)	NO135934C (en)
PL (1)	PL83097B1 (en)
SE (1)	SE393374B (en)
SU (1)	SU419023A3 (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4237068A (en) *	1971-07-28	1980-12-02	Astra Pharmaceutical Products, Inc.	Primary aminoacylanilides
US3966934A (en) *	1971-12-08	1976-06-29	Astra Pharmaceutical Products, Inc.	Synergistic local anesthetic compositions
US3957996A (en) *	1971-12-08	1976-05-18	Astra Pharmaceutical Products, Inc.	Pharmaceutical local anesthetic compositions
US3975443A (en) *	1972-06-06	1976-08-17	Allen & Hanburys Limited	1-(3,4-dichlorobenzamidomethyl)-cyclohexyldimethylamine
JPS598269B2 (en) *	1975-08-22	1984-02-23	萬有製薬株式会社	Omega - aminoalkanesane arylamide
EP0062322A1 (en) *	1981-04-03	1982-10-13	The B.F. GOODRICH Company	Improved process for synthesis of hindered amine stabilizers for polymeric materials
US4891058A (en) *	1988-07-18	1990-01-02	Ici Americas Inc.	1-alkyl-3-aryl imidazolidine-2,4-diones and herbicidal use
SE8900685D0 (en) *	1989-02-28	1989-02-28	Astra Ab	NEW COMPOUNDS
US5153226A (en) *	1989-08-31	1992-10-06	Warner-Lambert Company	Acat inhibitors for treating hypocholesterolemia
KR20140097446A (en)	2006-11-20	2014-08-06	프레지던트 앤드 펠로우즈 오브 하바드 칼리지	Methods, compositions, and kits for treating pain and pruritis
US20120172429A1 (en)	2009-07-10	2012-07-05	Woolf Clifford J	Permanently charged sodium and calcium channel blockers as anti- inflammatory agents
JP6833811B2 (en)	2015-08-03	2021-02-24	プレジデントアンドフェローズオブハーバードカレッジ	Charged ion channel blockers and how to use
CN113924094A (en)	2019-03-11	2022-01-11	诺西恩医疗公司	Ester-substituted ion channel blockers and methods of use
US10786485B1 (en)	2019-03-11	2020-09-29	Nocion Therapeutics, Inc.	Charged ion channel blockers and methods for use
KR20210143791A (en)	2019-03-11	2021-11-29	녹시온 테라퓨틱스 인코포레이티드	Charged Ion Channel Blockers and Methods of Use
JP7678757B2 (en)	2019-03-11	2025-05-16	ノシオンセラピューティクス，インコーポレイテッド	Charged ion channel blockers and methods of use - Patents.com
US10780083B1 (en)	2019-03-11	2020-09-22	Nocion Therapeutics, Inc.	Charged ion channel blockers and methods for use
WO2021091585A1 (en)	2019-11-06	2021-05-14	Nocion Therapeutics, Inc.	Charged ion channel blockers and methods for use
US10933055B1 (en)	2019-11-06	2021-03-02	Nocion Therapeutics, Inc.	Charged ion channel blockers and methods for use
KR20230022830A (en)	2020-03-11	2023-02-16	녹시온 테라퓨틱스 인코포레이티드	Charged ion channel blockers and methods of use
US12162851B2 (en)	2020-03-11	2024-12-10	Nocion Therapeutics, Inc.	Charged ion channel blockers and methods for use

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1124837A (en) *	1966-06-03	1968-08-21	Wyeth John & Brother Ltd	Substituted anilides

1971
- 1971-07-19 US US00164022A patent/US3812147A/en not_active Expired - Lifetime
- 1971-12-07 SE SE7115656A patent/SE393374B/en unknown
- 1971-12-14 BE BE776656A patent/BE776656A/en not_active IP Right Cessation
- 1971-12-15 SU SU1726195A patent/SU419023A3/en active
- 1971-12-16 HU HUAA690A patent/HU163373B/hu unknown
- 1971-12-17 NO NO4669/71A patent/NO135934C/no unknown
- 1971-12-17 DE DE2162744A patent/DE2162744C3/en not_active Expired
- 1971-12-17 DK DK619771AA patent/DK139814B/en not_active IP Right Cessation
- 1971-12-18 IT IT54845/71A patent/IT1066334B/en active
- 1971-12-20 AU AU37099/71A patent/AU468489B2/en not_active Expired
- 1971-12-20 IE IE1609/71A patent/IE35909B1/en unknown
- 1971-12-20 AT AT1089671A patent/AT319205B/en not_active IP Right Cessation
- 1971-12-21 ES ES398210A patent/ES398210A1/en not_active Expired
- 1971-12-21 AR AR239721A patent/AR193840A1/en active
- 1971-12-21 GB GB5937771A patent/GB1369259A/en not_active Expired
- 1971-12-21 DD DD159785A patent/DD99779A5/xx unknown
- 1971-12-21 CA CA130,662A patent/CA943966A/en not_active Expired
- 1971-12-21 PL PL1971152331A patent/PL83097B1/pl unknown
- 1971-12-21 FR FR7145983A patent/FR2118985B1/fr not_active Expired
- 1971-12-21 BR BR8466/71A patent/BR7108466D0/en unknown
- 1971-12-22 NL NLAANVRAGE7117644,A patent/NL172149C/en not_active IP Right Cessation
- 1971-12-22 FI FI3658/71A patent/FI55027C/en active
- 1971-12-22 JP JP10453571A patent/JPS5644063B1/ja active Pending
1974
- 1974-04-24 ES ES425626A patent/ES425626A1/en not_active Expired
1982
- 1982-10-26 NL NL8204126A patent/NL8204126A/en not_active Application Discontinuation

Also Published As

Publication number	Publication date
JPS5644063B1 (en)	1981-10-16
AU468489B2 (en)	1976-01-15
NL8204126A (en)	1983-02-01
ES425626A1 (en)	1976-06-16
DE2162744C3 (en)	1982-04-15
SU419023A3 (en)	1974-03-05
PL83097B1 (en)	1975-12-31
AU3709971A (en)	1973-06-28
FR2118985A1 (en)	1972-08-04
NL172149C (en)	1983-07-18
FI55027C (en)	1979-05-10
BR7108466D0 (en)	1973-06-14
HU163373B (en)	1973-08-28
FR2118985B1 (en)	1975-12-26
DE2162744A1 (en)	1972-07-06
DE2162744B2 (en)	1981-07-02
GB1369259A (en)	1974-10-23
NL172149B (en)	1983-02-16
ES398210A1 (en)	1975-03-16
NO135934B (en)	1977-03-21
AR193840A1 (en)	1973-05-31
DK139814C (en)	1979-10-01
SE393374B (en)	1977-05-09
IT1066334B (en)	1985-03-04
NO135934C (en)	1977-06-29
US3812147A (en)	1974-05-21
FI55027B (en)	1979-01-31
IE35909B1 (en)	1976-06-23
IE35909L (en)	1972-06-22
CA943966A (en)	1974-03-19
BE776656A (en)	1972-06-14
NL7117644A (en)	1972-06-26
DD99779A5 (en)	1973-08-20
AT319205B (en)	1974-12-10

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Legal Events

Date	Code	Title	Description
1988-08-29	PBP	Patent lapsed