[go: up one dir, main page]

DK139099B - Analogifremgangsmåde til fremstilling af 5,6-4H-dihydro-s-triazolo(4,3-a)benzodiazepiner-1,5. - Google Patents

Analogifremgangsmåde til fremstilling af 5,6-4H-dihydro-s-triazolo(4,3-a)benzodiazepiner-1,5.

Info

Publication number
DK139099B
DK139099B DK125874AA DK125874A DK139099B DK 139099 B DK139099 B DK 139099B DK 125874A A DK125874A A DK 125874AA DK 125874 A DK125874 A DK 125874A DK 139099 B DK139099 B DK 139099B
Authority
DK
Denmark
Prior art keywords
benzodiazepines
triazolo
dihydro
preparation
analogous process
Prior art date
Application number
DK125874AA
Other languages
English (en)
Other versions
DK139099C (da
Inventor
Etienne Szarvasi
Original Assignee
Lipha
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7308510A external-priority patent/FR2220257A1/fr
Priority claimed from FR7335522A external-priority patent/FR2246273A2/fr
Priority claimed from FR7341583A external-priority patent/FR2252102A2/fr
Application filed by Lipha filed Critical Lipha
Publication of DK139099B publication Critical patent/DK139099B/da
Application granted granted Critical
Publication of DK139099C publication Critical patent/DK139099C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK125874AA 1973-03-09 1974-03-08 Analogifremgangsmåde til fremstilling af 5,6-4H-dihydro-s-triazolo(4,3-a)benzodiazepiner-1,5. DK139099B (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR7308510A FR2220257A1 (en) 1973-03-09 1973-03-09 5,6-Dihydro-(4H)-s-triazolo-(4,3-a) (1,5)benzodiazepines - as antiinflam-matory and analgesic agents without tranquillising effects
FR7335522A FR2246273A2 (en) 1973-10-04 1973-10-04 5,6-Dihydro-(4H)-s-triazolo-(4,3-a) (1,5)benzodiazepines - as antiinflam-matory and analgesic agents without tranquillising effects
FR7341583A FR2252102A2 (en) 1973-11-22 1973-11-22 5,6-Dihydro-(4H)-s-triazolo-(4,3-a) (1,5)benzodiazepines - as antiinflam-matory and analgesic agents without tranquillising effects

Publications (2)

Publication Number Publication Date
DK139099B true DK139099B (da) 1978-12-18
DK139099C DK139099C (da) 1979-05-28

Family

ID=27250074

Family Applications (1)

Application Number Title Priority Date Filing Date
DK125874AA DK139099B (da) 1973-03-09 1974-03-08 Analogifremgangsmåde til fremstilling af 5,6-4H-dihydro-s-triazolo(4,3-a)benzodiazepiner-1,5.

Country Status (13)

Country Link
US (1) US4110337A (da)
JP (1) JPS49125395A (da)
CA (1) CA1011333A (da)
CH (1) CH589084A5 (da)
DD (1) DD110497A5 (da)
DE (1) DE2409308C3 (da)
DK (1) DK139099B (da)
ES (1) ES424067A1 (da)
GB (1) GB1409693A (da)
IE (1) IE38931B1 (da)
IL (1) IL44338A (da)
NL (1) NL7403247A (da)
NO (1) NO139048C (da)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4076823A (en) * 1977-08-18 1978-02-28 E. R. Squibb & Sons, Inc. Triazolo-2,4-benzodiazepines
WO1992018505A1 (fr) * 1991-04-23 1992-10-29 Toray Industries, Inc. Derive de triazole tricyclique, production et utilisation de ce derive
US5683998A (en) * 1991-04-23 1997-11-04 Toray Industries, Inc. Tricyclic triazolo derivatives, processes for producing the same and the uses of the same
FR2769309B1 (fr) 1997-10-08 2001-06-15 Oreal Composition de teinture d'oxydation des fibres keratiniques comprenant un derive d'aminoacide en tant que base d'oxydation et nouveaux derives d'aminoacides
US20050113460A1 (en) 1999-04-30 2005-05-26 The Regents Of The University Of Michigan Compositions and methods relating to novel compounds and targets thereof
US7276348B2 (en) * 1999-04-30 2007-10-02 Regents Of The University Of Michigan Compositions and methods relating to F1F0-ATPase inhibitors and targets thereof
US20040176358A1 (en) * 1999-04-30 2004-09-09 The Regents Of The University Of Michigan Compositions and methods relating to novel compounds and targets thereof
US20060025388A1 (en) * 1999-04-30 2006-02-02 Glick Gary D Compositions and methods relating to novel compounds and targets thereof
US7572788B2 (en) * 1999-04-30 2009-08-11 The Regents Of The University Of Michigan Compositions and methods relating to novel compounds and targets thereof
CA2372150C (en) 1999-04-30 2011-08-30 The Regents Of The University Of Michigan Therapeutic applications of pro-apoptotic benzodiazepines
US20030119029A1 (en) * 1999-04-30 2003-06-26 Regents Of The University Of Michigan Compositions and methods relating to novel benzodiazepine compounds and targets thereof
US20050272723A1 (en) * 2004-04-27 2005-12-08 The Regents Of The University Of Michigan Methods and compositions for treating diseases and conditions associated with mitochondrial function
US20060052369A1 (en) * 2004-09-07 2006-03-09 The Regents Of The University Of Michigan Compositions and methods relating to novel compounds and targets thereof
JP2008528448A (ja) * 2005-01-03 2008-07-31 ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン 新規化合物に関連する組成物および方法、ならびにその標的
AU2006309291B2 (en) 2005-06-01 2010-05-27 The Regents Of The University Of Michigan Unsolvated benzodiazepine compositions and methods
US20070105844A1 (en) * 2005-10-26 2007-05-10 Regents Of The University Of Michigan Therapeutic compositions and methods
NZ568254A (en) 2005-11-01 2011-06-30 Univ Michigan 1,4-Benzodiazepine-2,5-diones for regulating cell death and treating autoimmune diseases
DE102005061840A1 (de) 2005-12-23 2007-06-28 Merck Patent Gmbh Triazolderivate
US7759338B2 (en) * 2006-04-27 2010-07-20 The Regents Of The University Of Michigan Soluble 1,4 benzodiazepine compounds and stable salts thereof
JP5264716B2 (ja) 2006-06-09 2013-08-14 ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン 化合物およびその標的に関連する組成物および方法
KR101164718B1 (ko) 2007-03-09 2012-07-11 더 리젠츠 오브 더 유니버시티 오브 미시간 신규 화합물 및 이의 표적에 관한 조성물 및 방법
WO2009036175A2 (en) 2007-09-14 2009-03-19 The Regents Of The University Of Michigan F1f0-atpase inhibitors and related methods
AU2008323945B2 (en) 2007-11-06 2013-11-28 The Regents Of The University Of Michigan Benzodiazepinone compounds useful in the treatment of skin conditions
EP2352724B1 (en) 2008-09-11 2015-04-22 The Regents of the University of Michigan Aryl guanidine f1f0-atpase inhibitors and their medical use
US8604023B2 (en) 2009-04-17 2013-12-10 The Regents Of The University Of Michigan 1,4-benzodiazepinone compounds and their use in treating cancer
EP2470020A4 (en) 2009-09-18 2013-03-13 Univ Michigan BENZODIAZEPINONE COMPOUNDS AND TREATMENT METHODS THEREWITH
AU2010322286B2 (en) 2009-11-17 2014-06-05 The Regents Of The University Of Michigan 1,4-benzodiazepine-2,5-diones and related compounds with therapeutic properties
CA2780287C (en) 2009-11-17 2015-03-17 The Regents Of The University Of Michigan 1,4-benzodiazepine-2,5-diones and related compounds with therapeutic properties
AR084070A1 (es) 2010-12-02 2013-04-17 Constellation Pharmaceuticals Inc Inhibidores del bromodominio y usos de los mismos
US9249161B2 (en) 2010-12-02 2016-02-02 Constellation Pharmaceuticals, Inc. Bromodomain inhibitors and uses thereof
US9422292B2 (en) 2011-05-04 2016-08-23 Constellation Pharmaceuticals, Inc. Bromodomain inhibitors and uses thereof
US9328117B2 (en) 2011-06-17 2016-05-03 Constellation Pharmaceuticals, Inc. Bromodomain inhibitors and uses thereof
TWI602820B (zh) 2012-06-06 2017-10-21 星宿藥物公司 溴域抑制劑及其用途
WO2013184878A1 (en) 2012-06-06 2013-12-12 Constellation Pharmaceuticals, Inc. Benzo [b] isoxazoloazepine bromodomain inhibitors and uses thereof
ES2725928T3 (es) 2014-06-20 2019-09-30 Constellation Pharmaceuticals Inc Formas cristalinas de 2-((4S)-6-(4-clorofenil)-1-metil-4H-benzo[c]isoxazolo[4,5-e]azepin-4-il)acetamida

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3681343A (en) * 1971-05-11 1972-08-01 Upjohn Co 6-phenyl-s-triazolo{8 4,3-a{9 {8 1,4{9 {0 benzodiazepines

Also Published As

Publication number Publication date
AU6627674A (en) 1975-09-11
JPS49125395A (da) 1974-11-30
IE38931B1 (en) 1978-07-05
CH589084A5 (da) 1977-06-30
DE2409308B2 (de) 1977-09-22
DK139099C (da) 1979-05-28
IL44338A0 (en) 1974-06-30
IL44338A (en) 1977-01-31
DE2409308C3 (de) 1978-05-18
NO139048B (no) 1978-09-18
DD110497A5 (da) 1974-12-20
US4110337A (en) 1978-08-29
NO139048C (no) 1979-01-03
GB1409693A (en) 1975-10-15
NL7403247A (da) 1974-09-11
DE2409308A1 (de) 1974-09-19
ES424067A1 (es) 1976-06-01
IE38931L (en) 1974-09-09
NO740833L (no) 1974-09-10
CA1011333A (en) 1977-05-31

Similar Documents

Publication Publication Date Title
DK139099B (da) Analogifremgangsmåde til fremstilling af 5,6-4H-dihydro-s-triazolo(4,3-a)benzodiazepiner-1,5.
DK136718B (da) Analogifremgangsmåde til fremstilling af substituerede hexahydro-dibenzo(b,d)-pyran-9-oner.
DK136719B (da) Analogifremgangsmåde til fremstilling af substituerede hexahydro-dibenzo(b,d)-pyraner.
DK136075B (da) Analogifremgangsmåde til fremstilling af 11beta-hydroxy-16-methyl-3-oxo-17alfa-acyloxyandrosta-1,4,15-trien-17beta-carboxylater.
DK138791B (da) Analogifremgangsmåde til fremstilling af 2,6-disubstituerede fenylaminoguanidinforbindelser.
DK135711B (da) Analogifremgangsmåde til fremstilling af hidtil ukendte, hjerteaktive substituerede fenoxyisopropanolaminer.
DK134490B (da) Analogifremgangsmåde til fremstilling af 2,6-diaminonebularin-derivater.
DK139678B (da) Fremgangsmåde til fremstilling af 2,2,6,6-tetramethyl-4-oxopiperidin.
DK134031B (da) Fremgangsmåde til fremstilling af et endo-beta-glucanase-præparat.
DK140406B (da) Fremgangsmåde til fremstilling af 2,2,6,6-tetramethyl-4-oxopiperidin.
DK137389B (da) Analogifremgangsmåde til fremstilling af 11beta-substituerede delta4-østrener.
DK135723B (da) Analogifremgangsmåde til fremstilling af 7alfa-acylthio-3-oxo-D-homo-21,24-dinor-17aalfa-chlo-4-en-23,17a-lactoner.
DK132328B (da) Analogifremgangsmåde til fremstilling af 17beta-hydroxy-16,16-dimethylestr-4-en-3-on.
DK135167B (da) Analogifremgangsmåde til fremstilling af 7,7'-ditheophyllinderivater.
DK137043B (da) Analogifremgangsmåde til fremstilling af nitrocarbostyrilforbindelser.
DK131855B (da) Fremgangsmåde til fremstilling af 3,4-dihydropyridoner.
DK140480B (da) Analogifremgangsmåde til fremstilling af 2,8-substituerede D-6-alkylergoliner.
DK136619B (da) Fremgangsmåde til fremstilling af dihydrokanadensolid.
DK137928B (da) Fremgangsmåde til fremstilling af 5alfa-hydroxygona-9,11-diener.
DK136776B (da) Analogifremgangsmåde til fremstilling af 17aalfa-alkanoyloxy-D-homopregn-4-en-3,20-dioner.
DK132329B (da) Fremgangsmåde til fremstilling af cardenolid-3,alfa-/2'-desoxy-glycosider/.
DK124331B (da) Analogifremgangsmåde til fremstilling af 14β-hydroksy-15α-acyloksy-4,20(22)-kardadienolider.
DK138314B (da) Fremgangsmåde til fremstilling af racemisk 13beta-ætyl-3-metoxy-8,14-seco-gona-1,3,5(10),8-tetraen-17beta-ol-14-on.
DK134408B (da) Analogifremgangsmåde til fremstilling af 3-oxo-17beta-n-amyloxyestra-4,9,11-trien.
DK135133B (da) Fremgangsmåde til fremstilling af 21-fluor-16alfa,17alfa-alkylidendioxy-20-oxo-steroider.