DK122391A - Terapeutisk aktiv, substitueret benzimidazolderivat og fysiologisk acceptable salte heraf samt fremgangsmaade til fremstilling af samme - Google Patents

Terapeutisk aktiv, substitueret benzimidazolderivat og fysiologisk acceptable salte heraf samt fremgangsmaade til fremstilling af samme Download PDF

Info

Publication number: DK122391A
Authority: DK; Denmark
Prior art keywords: acceptable salts; physiologically acceptable; substituted; procedure; therapeutic activity
Prior art date: 1988-12-22

Application number

DK122391A

Other languages

English (en)

Other versions

DK170801B1 (da

DK122391D0 (da

Inventor

Arne Elof Braendstroem

Per Lennart Lindberg

Gunnel Elisabeth Sunden

Carl Ingemar Starke

Original Assignee

Haessle Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-12-22

Filing date

1991-06-21

Publication date

1991-06-24

1991-06-21 Application filed by Haessle Ab filed Critical Haessle Ab

1991-06-21 Publication of DK122391D0 publication Critical patent/DK122391D0/da

1991-06-24 Publication of DK122391A publication Critical patent/DK122391A/da

1996-01-22 Application granted granted Critical

1996-01-22 Publication of DK170801B1 publication Critical patent/DK170801B1/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pyridine Compounds (AREA)

DK122391A 1988-12-22 1991-06-21 Terapeutisk aktivt, substitueret benzimidazolderivat og fysiologisk acceptable salte og optiske enantiomerer heraf samt fremgangsmåde til fremstilling af samme, farmaceutisk præparat indeholdende benzimidazolderivatet, anvendelse af derivatet til fremstilling af et lægemiddel til hæmning af mavesyresekretionen hos pattedyr og til behandling af inflammatoriske mavetarmkanallidelser hos pattedyr sam DK170801B1 (da)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
SE8804628		1988-12-22
SE19888804628A SE8804628D0 (sv)	1988-12-22	1988-12-22	New compounds
SE8900741		1989-03-13
PCT/SE1989/000741 WO1990006926A1 (en)	1988-12-22	1989-12-20	Therapeutically active substituted benzimidazole and process for its preparation

Publications (3)

Publication Number	Publication Date
DK122391D0 DK122391D0 (da)	1991-06-21
DK122391A true DK122391A (da)	1991-06-24
DK170801B1 DK170801B1 (da)	1996-01-22

Family

ID=20374309

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK122391A DK170801B1 (da)	1988-12-22	1991-06-21	Terapeutisk aktivt, substitueret benzimidazolderivat og fysiologisk acceptable salte og optiske enantiomerer heraf samt fremgangsmåde til fremstilling af samme, farmaceutisk præparat indeholdende benzimidazolderivatet, anvendelse af derivatet til fremstilling af et lægemiddel til hæmning af mavesyresekretionen hos pattedyr og til behandling af inflammatoriske mavetarmkanallidelser hos pattedyr sam

Country Status (26)

Country	Link
US (1)	US5019584A (da)
EP (1)	EP0451188B1 (da)
JP (1)	JP2793907B2 (da)
CN (1)	CN1028232C (da)
AT (1)	ATE110379T1 (da)
AU (1)	AU636866B2 (da)
CA (1)	CA2005987C (da)
DD (1)	DD296077A5 (da)
DE (1)	DE68917738T2 (da)
DK (1)	DK170801B1 (da)
FI (1)	FI913036A7 (da)
GR (1)	GR1000318B (da)
HU (1)	HUT57203A (da)
IE (1)	IE64850B1 (da)
IL (1)	IL92797A (da)
LT (1)	LT3981B (da)
LV (1)	LV10268B (da)
NO (1)	NO178338C (da)
PH (1)	PH27257A (da)
PT (1)	PT92647B (da)
RO (1)	RO110496B1 (da)
RU (1)	RU2070199C1 (da)
SE (1)	SE8804628D0 (da)
WO (1)	WO1990006926A1 (da)
YU (1)	YU242589A (da)
ZA (1)	ZA899796B (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE184602T1 (de) *	1990-06-20	1999-10-15	Astra Ab	Dialkoxypyridinylbenzimidazolderivate, verfahren zur herstellung und ihre pharmazeutische verwendung
NZ244301A (en) *	1991-09-20	1994-08-26	Merck & Co Inc	Preparation of 2-pyridylmethylsulphinylbenzimidazole and pyridoimidazole derivatives from the corresponding sulphenyl compounds
US6016044A (en) *	1995-09-11	2000-01-18	Alaris Medical Systems, Inc.	Open-loop step motor control system
US6489346B1 (en)	1996-01-04	2002-12-03	The Curators Of The University Of Missouri	Substituted benzimidazole dosage forms and method of using same
US6645988B2 (en) *	1996-01-04	2003-11-11	Curators Of The University Of Missouri	Substituted benzimidazole dosage forms and method of using same
US5840737A (en)	1996-01-04	1998-11-24	The Curators Of The University Of Missouri	Omeprazole solution and method for using same
US6699885B2 (en)	1996-01-04	2004-03-02	The Curators Of The University Of Missouri	Substituted benzimidazole dosage forms and methods of using same
RU2144823C1 (ru) *	1998-11-20	2000-01-27	Научно-исследовательский институт фармакологии Томского научного центра РАМН	Лекарственное средство, обладающее слабительным действием
JP2005521662A (ja) *	2002-01-25	2005-07-21	サンタラスインコーポレイティッド	プロトンポンプ阻害剤の経粘膜送達
AU2003224781A1 (en) *	2002-03-26	2003-10-13	Dr. Reddy's Laboratories Limited	Crystalline forms of rabeprazole sodium
WO2004073654A2 (en) *	2003-02-20	2004-09-02	Santarus, Inc.	A novel formulation, omeprazole antacid complex-immediate release for rapid and sustained supression of gastric acid
CA2531566C (en) *	2003-07-18	2013-05-07	Santarus, Inc.	Pharmaceutical formulation and method for treating acid-caused gastrointestinal disorders
US8993599B2 (en) *	2003-07-18	2015-03-31	Santarus, Inc.	Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
MXPA06000529A (es) *	2003-07-18	2006-08-11	Santarus Inc	Formulaciones farmaceuticas utiles para inhibir la secrecion de acido y metodos para elaborarlas y utilizarlas.
US20070292498A1 (en) *	2003-11-05	2007-12-20	Warren Hall	Combinations of proton pump inhibitors, sleep aids, buffers and pain relievers
US8906940B2 (en) *	2004-05-25	2014-12-09	Santarus, Inc.	Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US8815916B2 (en) *	2004-05-25	2014-08-26	Santarus, Inc.	Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US20090092658A1 (en) *	2007-10-05	2009-04-09	Santarus, Inc.	Novel formulations of proton pump inhibitors and methods of using these formulations

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE418966B (sv)	1974-02-18	1981-07-06	Haessle Ab	Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan
SE416649B (sv)	1974-05-16	1981-01-26	Haessle Ab	Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
IN148930B (da)	1977-09-19	1981-07-25	Hoffmann La Roche
SE7804231L (sv)	1978-04-14	1979-10-15	Haessle Ab	Magsyrasekretionsmedel
US4359465A (en)	1980-07-28	1982-11-16	The Upjohn Company	Methods for treating gastrointestinal inflammation
CH644116A5 (de)	1980-08-21	1984-07-13	Hoffmann La Roche	Imidazolderivate.
US4331671A (en) *	1981-01-09	1982-05-25	Sterling Drug Inc.	5-(Pyridinyl)-1H-benzimidazoles and 1-hydroxy-6-(pyridinyl)-1H-benzimidazoles and their cardiotonic use
HU195220B (en)	1983-05-03	1988-04-28	Byk Gulden Lomberg Chem Fqb	Process for production of new fluor-alkoxi-benzimidasole-derivatives and medical compositions containig them
JPS6150979A (ja)	1984-08-16	1986-03-13	Takeda Chem Ind Ltd	ピリジン誘導体およびその製造法
JPS6150978A (ja)	1984-08-16	1986-03-13	Takeda Chem Ind Ltd	ピリジン誘導体およびその製造法
SE8500996D0 (sv) *	1985-03-01	1985-03-01	Haessle Ab	Method of treatment
US4738975A (en) *	1985-07-02	1988-04-19	Takeda Chemical Industries, Ltd.	Pyridine derivatives, and use as anti-ulcer agents
GB8610607D0 (en) *	1986-04-30	1986-06-04	Smith Kline French Lab	Chemical compounds
FR2593178B1 (fr) *	1986-01-20	1988-04-29	Esteve Labor Dr	Derives de 2-benzimidazolylalkylthio (ou sulfinyle ou sulfonyle) leur preparation et leur application en tant que medicaments.
EP0338066A1 (en) *	1987-10-30	1989-10-25	Aktiebolaget Hässle	2-pyridinylmethyl (sulfinyl or thio)benzimidazoles for treatment of diseases related to bone loss

1988
- 1988-12-22 SE SE19888804628A patent/SE8804628D0/xx unknown
1989
- 1989-12-18 IE IE404989A patent/IE64850B1/xx not_active IP Right Cessation
- 1989-12-19 CA CA002005987A patent/CA2005987C/en not_active Expired - Lifetime
- 1989-12-19 PH PH39730A patent/PH27257A/en unknown
- 1989-12-19 GR GR890100834A patent/GR1000318B/el unknown
- 1989-12-19 IL IL9279789A patent/IL92797A/en not_active IP Right Cessation
- 1989-12-20 JP JP2501538A patent/JP2793907B2/ja not_active Expired - Fee Related
- 1989-12-20 HU HU901085A patent/HUT57203A/hu unknown
- 1989-12-20 EP EP90901080A patent/EP0451188B1/en not_active Expired - Lifetime
- 1989-12-20 WO PCT/SE1989/000741 patent/WO1990006926A1/en not_active Ceased
- 1989-12-20 AT AT90901080T patent/ATE110379T1/de not_active IP Right Cessation
- 1989-12-20 DD DD89335979A patent/DD296077A5/de not_active IP Right Cessation
- 1989-12-20 RU SU894895822A patent/RU2070199C1/ru active
- 1989-12-20 US US07/454,046 patent/US5019584A/en not_active Expired - Lifetime
- 1989-12-20 FI FI913036A patent/FI913036A7/fi not_active Application Discontinuation
- 1989-12-20 RO RO147868A patent/RO110496B1/ro unknown
- 1989-12-20 AU AU48176/90A patent/AU636866B2/en not_active Ceased
- 1989-12-20 DE DE68917738T patent/DE68917738T2/de not_active Expired - Fee Related
- 1989-12-20 ZA ZA899796A patent/ZA899796B/xx unknown
- 1989-12-21 YU YU02425/89A patent/YU242589A/xx unknown
- 1989-12-21 PT PT92647A patent/PT92647B/pt not_active IP Right Cessation
- 1989-12-21 CN CN89109588A patent/CN1028232C/zh not_active Expired - Fee Related
1991
- 1991-06-20 NO NO912416A patent/NO178338C/no unknown
- 1991-06-21 DK DK122391A patent/DK170801B1/da not_active IP Right Cessation
1993
- 1993-06-28 LV LVP-93-692A patent/LV10268B/lv unknown
- 1993-12-30 LT LTIP1722A patent/LT3981B/lt not_active IP Right Cessation

Also Published As

Publication number	Publication date
JP2793907B2 (ja)	1998-09-03
DE68917738D1 (de)	1994-09-29
HU901085D0 (en)	1991-09-30
NO912416L (no)	1991-07-31
SE8804628D0 (sv)	1988-12-22
JPH04502462A (ja)	1992-05-07
DK170801B1 (da)	1996-01-22
CA2005987C (en)	1999-04-13
YU242589A (en)	1991-04-30
HUT57203A (en)	1991-11-28
PT92647A (pt)	1990-06-29
CN1028232C (zh)	1995-04-19
ZA899796B (en)	1990-08-29
NO178338C (no)	1996-03-06
US5019584A (en)	1991-05-28
AU636866B2 (en)	1993-05-13
IL92797A (en)	1994-12-29
RU2070199C1 (ru)	1996-12-10
IL92797A0 (en)	1990-09-17
ATE110379T1 (de)	1994-09-15
LTIP1722A (en)	1995-07-25
AU4817690A (en)	1990-07-10
IE64850B1 (en)	1995-09-06
LT3981B (en)	1996-06-25
NO912416D0 (no)	1991-06-20
IE894049L (en)	1990-06-22
LV10268A (lv)	1994-10-20
DK122391D0 (da)	1991-06-21
LV10268B (en)	1995-02-20
FI913036A0 (fi)	1991-06-20
GR1000318B (el)	1992-06-25
DE68917738T2 (de)	1994-12-22
WO1990006926A1 (en)	1990-06-28
NO178338B (no)	1995-11-27
GR890100834A (en)	1991-03-15
DD296077A5 (de)	1991-11-21
EP0451188A1 (en)	1991-10-16
CN1043714A (zh)	1990-07-11
PT92647B (pt)	1995-09-12
RO110496B1 (ro)	1996-01-30
PH27257A (en)	1993-05-04
FI913036A7 (fi)	1991-06-20
CA2005987A1 (en)	1990-06-22
EP0451188B1 (en)	1994-08-24

Publication	Publication Date	Title
DK122291A (da)	1991-06-24	Benzimidazolderivat og fysiologisk acceptable salte heraf samt fremgangsmaade til fremstilling af samme
DK122391A (da)	1991-06-24	Terapeutisk aktiv, substitueret benzimidazolderivat og fysiologisk acceptable salte heraf samt fremgangsmaade til fremstilling af samme
NO882732L (no)	1988-12-23	Fremgangsmaate for fremstilling av terapeutisk aktive aminosyrederivater.
NO904694L (no)	1991-05-02	Fremgangsmaate for fremstilling av terapeutisk aktive imidazolderivater.
NO901684L (no)	1990-10-19	Fremgangsmaate for fremstilling av terapeutisk aktive 3-substituerte-2-oksindol-derivater.
NO167202C (no)	1991-10-16	Analogifremgangsmaate for fremstilling av terapeutisk aktive (1h-imidazol-1-ylmetyl)-substituerte benzimidazolderivater.
FI885460L (fi)	1988-11-24	Menetelmä suun kautta annettavaksi tarkoitetun, aktiiviyhdistettä kontrolloidusti vapauttavan farmaseuttisen formulaation valmistamiseksi
NO871295D0 (no)	1987-03-27	Fremgangsmaate for fremstilling av terapeutisk aktive aminosyrederivater.
NO883122L (no)	1989-01-17	Fremgangsmaate for fremstilling av terapeutisk aktive arylamid-derivater.
NO167204C (no)	1991-10-23	Analogifremgangsmaate for fremstilling av terapeutisk aktive diacylderivater av 4-(trialkylbenzyl)-piperazinylforbindelser.
NO870049L (no)	1987-07-08	Analogifremgangsmaate for fremstilling av terapeutisk aktive aminosyrederivater.
NO178336C (no)	1996-03-06	Analogifremgangsmåte for fremstilling av en terapeutisk aktiv benzimidazolforbindelse og mellomprodukter
NO167734C (no)	1991-12-04	Analogifremgangsmaate for fremstilling av terapeutisk aktive substituerte aminderivater.
NO902710D0 (no)	1990-06-19	Analogifremgangsmaate for fremstilling av terapeutisk aktive r(-) 3-kinuklidinol-derivater.
NO874850D0 (no)	1987-11-20	Fremgangsmaate for fremstilling av benzotiadiazinforbindelser og farmasoeytisk akseptable salter derav.
NO884175L (no)	1989-03-22	Fremgangsmaate for fremstilling av terapeutiske aktive heterocykliske derivater.
NO913644D0 (no)	1991-09-16	Fremgangsmaate for fremstilling av terapeutisk aktive aminosyrederivater.
NO172491C (no)	1993-07-28	Analogifremgangsmaate for fremstilling av terapeutisk aktive 1,3-dioksan-alkensyre-dervater
NO900972L (no)	1990-09-04	Fremgangsmaate for fremstilling av terapeutisk aktive naftalen-derivater.
NO874780D0 (no)	1987-11-17	Analogifremgangsmaate for fremstilling av terapeutisk aktive pyrrolo-benzimidazol-derivater.
NO900942D0 (no)	1990-02-28	Fremgangsmaate for fremstilling av terapeutisk aktive azacyklooktadien-derivater.
NO167381C (no)	1991-10-30	Analogifremgangsmaate for fremstilling av terapeutisk aktiv (e)-2-(p-fluorfenethyl)-3-fluorallylamin.
NO172120C (no)	1993-06-09	Analogifremgangsmaate for fremstilling av terapeutisk aktive isoxazoler
NO167511C (no)	1991-11-13	Analogifremgangsmaate for fremstilling av terapeutisk aktive substituerte tieno(3,4-d)imidazolderivater.
NO890502D0 (no)	1989-02-07	Fremgangsmaate for fremstilling av terapeutisk aktive etanolamin-derivater.

Legal Events

Date	Code	Title	Description
1996-01-22	B1	Patent granted (law 1993)
1997-08-25	PBP	Patent lapsed