DK1285908T3 - Substituerede phenylpropionsyrederivater - Google Patents

Substituerede phenylpropionsyrederivater

Info

Publication number: DK1285908T3
Authority: DK; Denmark
Prior art keywords: group; carbon atoms; denotes; acid derivatives; unsubstituted
Prior art date: 2000-05-29

Application number

DK01932262T

Other languages

English (en)

Inventor

Hiroyuki Miyachi

Masahiro Nomura

Yukie Takahashi

Takahiro Tanase

Kouji Murakami

Masahiro Suzuki

Original Assignee

Kyorin Seiyaku Kk

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-05-29

Filing date

2001-05-25

Publication date

2008-12-01

2001-05-25 Application filed by Kyorin Seiyaku Kk filed Critical Kyorin Seiyaku Kk

2008-12-01 Application granted granted Critical

2008-12-01 Publication of DK1285908T3 publication Critical patent/DK1285908T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
- C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
- C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
- C07C233/46—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/51—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to an acyclic carbon atom of a carbon skeleton containing six-membered aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
- C07C233/53—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
- C07C233/55—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a carbon atom of an unsaturated carbon skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
- C07C233/81—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
- C07C233/82—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/87—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom of a carbon skeleton containing six-membered aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C235/38—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/44—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
- C07C235/52—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/32—Oximes
- C07C251/34—Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
- C07C251/48—Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with the carbon atom of at least one of the oxyimino groups bound to a carbon atom of a six-membered aromatic ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/56—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/734—Ethers
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/738—Esters of keto-carboxylic acids or aldehydo-carboxylic acids

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK01932262T 2000-05-29 2001-05-25 Substituerede phenylpropionsyrederivater DK1285908T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP2000158424		2000-05-29
PCT/JP2001/004385 WO2001092201A1 (fr)	2000-05-29	2001-05-25	Derives substitues d'acide phenylpropionique

Publications (1)

Publication Number	Publication Date
DK1285908T3 true DK1285908T3 (da)	2008-12-01

Family

ID=18662898

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK01932262T DK1285908T3 (da)	2000-05-29	2001-05-25	Substituerede phenylpropionsyrederivater

Country Status (13)

Country	Link
EP (1)	EP1285908B9 (da)
JP (1)	JP4803946B2 (da)
AT (1)	ATE407919T1 (da)
AU (1)	AU2001258838A1 (da)
CA (1)	CA2410647C (da)
CY (1)	CY1108586T1 (da)
DE (1)	DE60135742D1 (da)
DK (1)	DK1285908T3 (da)
ES (1)	ES2312432T3 (da)
PT (1)	PT1285908E (da)
SI (1)	SI1285908T1 (da)
TW (1)	TWI305773B (da)
WO (1)	WO2001092201A1 (da)

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WO2002081428A1 (en) *	2001-03-30	2002-10-17	Eisai Co., Ltd.	Benzene compound and salt thereof
TWI311133B (en)	2001-04-20	2009-06-21	Eisai R&D Man Co Ltd	Carboxylic acid derivativeand the salt thereof
JPWO2003016265A1 (ja)	2001-08-17	2004-12-02	エーザイ株式会社	環状化合物およびｐｐａｒアゴニスト
ITRM20020014A1 (it) *	2002-01-15	2003-07-15	Sigma Tau Ind Farmaceuti	Derivati di acidi a-feniltiocarbossilici e a-fenilossicarbossilici utili per il trattamento di patologie che rispondono all'attivazione del
EP1614417A4 (en) *	2003-04-16	2007-08-29	Kyorin Seiyaku Kk	SOLID PREPARATION FOR ORAL USE
US7348338B2 (en)	2003-07-17	2008-03-25	Plexxikon, Inc.	PPAR active compounds
RU2356889C2 (ru)	2003-07-17	2009-05-27	Плекссикон, Инк.	Соединения, являющиеся активными по отношению к рецепторам, активируемым пролифератором пероксисом
AR048931A1 (es) *	2004-04-21	2006-06-14	Janssen Pharmaceutica Nv	Proceso para la preparacion de derivados de tetralina sustituida e indano sustituido y preparacion de intermediarios de sintesis
AU2005311925A1 (en)	2004-11-30	2006-06-08	Plexxikon, Inc.	Indole derivatives for use as PPAR PPAR active compounds
JP2007001912A (ja) *	2005-06-22	2007-01-11	Univ Of Tokyo	置換フェニルプロピオン酸誘導体
CA2613517A1 (en)	2005-06-27	2007-01-04	Exelixis, Inc.	Pyrazole based lxr modulators
ITRM20050390A1 (it)	2005-07-22	2007-01-23	Giuliani Spa	Composti e loro sali specifici per i recettori ppar ed i recettori per l'egf e loro uso in campo medico.
ITRM20050389A1 (it)	2005-07-22	2007-01-23	Giuliani Spa	Composti e loro sali specifici per i recettori ppar ed i recettori per l'egf e loro uso in campo medico.
BRPI0615948A2 (pt) *	2005-09-07	2011-05-31	Plexxikon Inc	composto ativo de ppar, sua composição, seu kit e seu uso
UA95613C2 (ru) *	2005-11-09	2011-08-25	Уеллстат Терепьютикс Корпорейшн	Соединения для лечения расстройсв метаболизма
JP5147071B2 (ja) *	2006-07-03	2013-02-20	国立大学法人東京大学	α−置換フェニルプロピオン酸誘導体
EP2121621B1 (en)	2006-12-08	2014-05-07	Exelixis Patent Company LLC	Lxr and fxr modulators
PE20090159A1 (es)	2007-03-08	2009-02-21	Plexxikon Inc	COMPUESTOS DERIVADOS DE ACIDO INDOL-PROPIONICO COMO MODULADORES PPARs
DE102008018675A1 (de)	2008-04-14	2009-10-15	Bayer Schering Pharma Aktiengesellschaft	Oxo-heterocyclisch substituierte Carbonsäure-Derivate und ihre Verwendung
UA107562C2 (uk)	2008-12-05	2015-01-26		Спосіб лікування псоріазу
CA2752626C (en)	2009-02-16	2018-03-27	Giuliani International Limited	Use of ppar modulators in treating hair related conditions
DE102009012314A1 (de)	2009-03-09	2010-09-16	Bayer Schering Pharma Aktiengesellschaft	Oxo-heterocyclisch substituierte Alkylcarbonsäuren und ihre Verwendung
DE102009046115A1 (de)	2009-10-28	2011-09-08	Bayer Schering Pharma Aktiengesellschaft	Substituierte 3-Phenylpropansäuren und ihre Verwendung
CN103492361B (zh) *	2010-12-07	2015-07-15	拜耳知识产权有限责任公司	取代的1-苄基环烷基羧酸及其用途
DE102011006974A1 (de)	2011-04-07	2012-10-11	Bayer Pharma Aktiengesellschaft	Substituierte 1-Benzylcycloalkylcarbonsäuren und ihre Verwendung
DE102011007272A1 (de)	2011-04-13	2012-10-18	Bayer Pharma Aktiengesellschaft	Verzweigte 3-Phenylpropionsäure-Derivate und ihre Verwendung
CA2864059C (en)	2012-02-09	2020-04-28	Nogra Pharma Limited	Methods of treating fibrosis
EA201491894A1 (ru)	2012-04-18	2015-02-27	Ногра Фарма Лимитед	Способы лечения непереносимости лактозы
DE102012208530A1 (de)	2012-05-22	2013-11-28	Bayer Pharma AG	Substituierte Piperidinoacetamide und ihre Verwendung
JPWO2015046317A1 (ja) *	2013-09-30	2017-03-09	国立大学法人岡山大学	新規アセチレンアミド誘導体
CN104356000B (zh) *	2014-11-18	2016-09-28	响水恒利达科技化工有限公司	一种3-硝基-4-甲氧基苯甲酸的制备方法
US12473312B2 (en)	2018-03-16	2025-11-18	The Board Of Regents Of The University Of Oklahoma	Agonists of peroxisome proliferator-activated receptor alpha (PPAR+60 ) and methods of use
CN112351975B (zh) *	2018-03-16	2024-07-16	俄克拉何马大学董事会	过氧化物酶体增殖物活化受体α的激动剂和使用方法
US10905667B2 (en)	2018-07-24	2021-02-02	Bayer Pharma Aktiengesellschaft	Orally administrable modified-release pharmaceutical dosage form
HUE070120T2 (hu)	2019-02-08	2025-05-28	Nogra Pharma Ltd	Eljárás 3-(4'-aminofenil)-2-metoxipropionsav és analógjai és intermedierei elõállítására

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AU2337097A (en) *	1996-03-29	1997-10-22	G.D. Searle & Co.	Meta-substituted phenylene derivatives and their use as alphavbeta3 integrin antagonists or inhibitors
JP3215048B2 (ja) *	1996-04-03	2001-10-02	日本たばこ産業株式会社	プロピオン酸誘導体及びその用途
CA2263721A1 (en) *	1996-08-19	1998-02-26	Satoshi Ohrui	Propionic acid derivatives and applications thereof
JP4618845B2 (ja) *	1999-06-09	2011-01-26	杏林製薬株式会社	ヒトペルオキシゾーム増殖薬活性化受容体（ＰＰＡＲ）αアゴニストとしての置換フェニルプロピオン酸誘導体
TWI262185B (en) *	1999-10-01	2006-09-21	Eisai Co Ltd	Carboxylic acid derivatives having anti-hyperglycemia and anti-hyperlipemia action, and pharmaceutical composition containing the derivatives

2001
- 2001-05-25 DK DK01932262T patent/DK1285908T3/da active
- 2001-05-25 EP EP01932262A patent/EP1285908B9/en not_active Expired - Lifetime
- 2001-05-25 JP JP2002500817A patent/JP4803946B2/ja not_active Expired - Fee Related
- 2001-05-25 WO PCT/JP2001/004385 patent/WO2001092201A1/ja not_active Ceased
- 2001-05-25 SI SI200130861T patent/SI1285908T1/sl unknown
- 2001-05-25 ES ES01932262T patent/ES2312432T3/es not_active Expired - Lifetime
- 2001-05-25 DE DE60135742T patent/DE60135742D1/de not_active Expired - Lifetime
- 2001-05-25 PT PT01932262T patent/PT1285908E/pt unknown
- 2001-05-25 CA CA2410647A patent/CA2410647C/en not_active Expired - Fee Related
- 2001-05-25 AT AT01932262T patent/ATE407919T1/de active
- 2001-05-25 AU AU2001258838A patent/AU2001258838A1/en not_active Abandoned
- 2001-05-28 TW TW090112780A patent/TWI305773B/zh not_active IP Right Cessation
2008
- 2008-11-24 CY CY20081101345T patent/CY1108586T1/el unknown

Also Published As

Publication number	Publication date
CY1108586T1 (el)	2014-04-09
CA2410647C (en)	2010-02-09
EP1285908A4 (en)	2005-09-21
PT1285908E (pt)	2008-12-04
EP1285908B9 (en)	2009-04-22
ES2312432T3 (es)	2009-03-01
CA2410647A1 (en)	2002-11-28
WO2001092201A1 (fr)	2001-12-06
AU2001258838A1 (en)	2001-12-11
ATE407919T1 (de)	2008-09-15
DE60135742D1 (de)	2008-10-23
EP1285908A1 (en)	2003-02-26
JP4803946B2 (ja)	2011-10-26
SI1285908T1 (sl)	2008-12-31
TWI305773B (en)	2009-02-01
EP1285908B1 (en)	2008-09-10

Publication	Publication Date	Title
CY1108586T1 (el)	2014-04-09	Υποκαταστημενα παραγωγα φαινυλοπροπιονικου οξεος
ATE296294T1 (de)	2005-06-15	Substituierte benzylthiazolidin-2,4-dion-derivate
ATE288887T1 (de)	2005-02-15	Substituierte phenylpropionsäurederivate als agonisten des menschlichen peroxisom-proliferator-aktiverten rezeptors alpha(ppar)
DE60020573D1 (de)	2005-07-07	Substituierte benzylthiazolidin-2,4-dion derivate
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