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DK127880C - Analogifremgangsmåde til fremstilling af 3-oxo-1,2α-methylen-??dihalogenmethylen-20-spirox-4-en-forbindelser. - Google Patents

Analogifremgangsmåde til fremstilling af 3-oxo-1,2α-methylen-??dihalogenmethylen-20-spirox-4-en-forbindelser.

Info

Publication number
DK127880C
DK127880C DK590571AA DK590571A DK127880C DK 127880 C DK127880 C DK 127880C DK 590571A A DK590571A A DK 590571AA DK 590571 A DK590571 A DK 590571A DK 127880 C DK127880 C DK 127880C
Authority
DK
Denmark
Prior art keywords
spirox
dihalomethylene
oxo
methylene
preparation
Prior art date
Application number
DK590571AA
Other languages
English (en)
Other versions
DK127880B (da
Inventor
Glen Edward Arth
Henry Rasmusson
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of DK127880B publication Critical patent/DK127880B/da
Application granted granted Critical
Publication of DK127880C publication Critical patent/DK127880C/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK590571AA 1969-05-14 1971-12-02 Analogifremgangsmåde til fremstilling af 3-oxo-1,2α-methylen-??dihalogenmethylen-20-spirox-4-en-forbindelser. DK127880C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US82467269A 1969-05-14 1969-05-14
US2118370A 1970-03-19 1970-03-19

Publications (2)

Publication Number Publication Date
DK127880B DK127880B (da) 1974-01-28
DK127880C true DK127880C (da) 1974-06-10

Family

ID=26694377

Family Applications (3)

Application Number Title Priority Date Filing Date
DK243670AA DK126992B (da) 1969-05-14 1970-05-13 Analogifremgangsmåde til fremstilling af 1,2α-methylen-6,7α-dihalogenmethylen-20-spirox-4-en-3-on-forbindelser.
DK377671AA DK127505B (da) 1969-05-14 1971-08-02 Analogifremgangsmåde til fremstilling af 3,21-dioxygenerede 1,2α-methylen-6,7α-dihalogenmethylen-20-spirox-4-en-forbindelser.
DK590571AA DK127880C (da) 1969-05-14 1971-12-02 Analogifremgangsmåde til fremstilling af 3-oxo-1,2α-methylen-??dihalogenmethylen-20-spirox-4-en-forbindelser.

Family Applications Before (2)

Application Number Title Priority Date Filing Date
DK243670AA DK126992B (da) 1969-05-14 1970-05-13 Analogifremgangsmåde til fremstilling af 1,2α-methylen-6,7α-dihalogenmethylen-20-spirox-4-en-3-on-forbindelser.
DK377671AA DK127505B (da) 1969-05-14 1971-08-02 Analogifremgangsmåde til fremstilling af 3,21-dioxygenerede 1,2α-methylen-6,7α-dihalogenmethylen-20-spirox-4-en-forbindelser.

Country Status (17)

Country Link
JP (1) JPS532865B1 (da)
AR (1) AR192305A1 (da)
BE (1) BE750330A (da)
CA (1) CA926385A (da)
CH (2) CH547785A (da)
CS (2) CS151552B2 (da)
DE (1) DE2023450C3 (da)
DK (3) DK126992B (da)
FI (2) FI47355C (da)
FR (1) FR2051526B1 (da)
GB (1) GB1265444A (da)
IE (1) IE34194B1 (da)
IL (1) IL34431A (da)
NL (1) NL168844C (da)
NO (1) NO131131C (da)
SE (2) SE366305B (da)
YU (1) YU34052B (da)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3356677A (en) * 1966-04-05 1967-12-05 Syntex Corp 1alpha, 2alpha-and 6alpha, 7alpha-dihalomethylene androstenes

Also Published As

Publication number Publication date
CS151551B2 (da) 1973-10-19
FI47885C (fi) 1974-04-10
NL168844C (nl) 1982-05-17
NL7006474A (da) 1970-11-17
FR2051526A1 (da) 1971-04-09
DE2023450B2 (de) 1978-10-05
DK127880B (da) 1974-01-28
IE34194L (en) 1970-11-14
DK127505B (da) 1973-11-19
CA926385A (en) 1973-05-15
SE366305B (da) 1974-04-22
GB1265444A (da) 1972-03-01
CH547792A (de) 1974-04-11
FI47355B (da) 1973-07-31
AR192305A1 (es) 1973-02-14
DK126992B (da) 1973-09-10
NL168844B (nl) 1981-12-16
FI47885B (da) 1974-01-02
CS151552B2 (da) 1973-10-19
IL34431A (en) 1974-03-14
YU34052B (en) 1978-10-31
IL34431A0 (en) 1970-07-19
BE750330A (fr) 1970-11-13
DE2023450C3 (de) 1979-05-31
DE2023450A1 (de) 1971-01-14
SE386904B (sv) 1976-08-23
NO131131C (da) 1975-04-09
YU117670A (en) 1978-05-15
CH547785A (de) 1974-04-11
FR2051526B1 (da) 1974-04-12
FI47355C (fi) 1973-11-12
IE34194B1 (en) 1975-03-05
JPS532865B1 (da) 1978-02-01
NO131131B (da) 1974-12-30

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