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DK107100C - Process for the preparation of fluorosubstituted 7-nitro-1,4-benzodiazepine compounds or acid addition salts thereof. - Google Patents

Process for the preparation of fluorosubstituted 7-nitro-1,4-benzodiazepine compounds or acid addition salts thereof.

Info

Publication number
DK107100C
DK107100C DK111363A DK111363A DK107100C DK 107100 C DK107100 C DK 107100C DK 111363 A DK111363 A DK 111363A DK 111363 A DK111363 A DK 111363A DK 107100 C DK107100 C DK 107100C
Authority
DK
Denmark
Prior art keywords
fluorosubstituted
nitro
preparation
acid addition
addition salts
Prior art date
Application number
DK111363A
Other languages
Danish (da)
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of DK107100C publication Critical patent/DK107100C/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • C07D243/28Preparation including building-up the benzodiazepine skeleton from compounds containing no hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK111363A 1962-03-21 1963-03-11 Process for the preparation of fluorosubstituted 7-nitro-1,4-benzodiazepine compounds or acid addition salts thereof. DK107100C (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US18144062A 1962-03-21 1962-03-21

Publications (1)

Publication Number Publication Date
DK107100C true DK107100C (en) 1967-04-24

Family

ID=22664289

Family Applications (1)

Application Number Title Priority Date Filing Date
DK111363A DK107100C (en) 1962-03-21 1963-03-11 Process for the preparation of fluorosubstituted 7-nitro-1,4-benzodiazepine compounds or acid addition salts thereof.

Country Status (7)

Country Link
BR (1) BR6347165D0 (en)
CH (3) CH455814A (en)
DE (1) DE1445872A1 (en)
DK (1) DK107100C (en)
ES (1) ES286241A1 (en)
GB (1) GB1039372A (en)
SE (1) SE312808B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2529203A1 (en) * 1982-06-24 1983-12-30 Fabre Sa Pierre INDUSTRIAL PROCESS FOR OBTAINING AND PURIFYING PHARMACEUTICAL-QUALITY FLUNITRAZEPAM

Also Published As

Publication number Publication date
CH454888A (en) 1968-04-30
CH441342A (en) 1967-08-15
ES286241A1 (en) 1963-11-16
DE1445872A1 (en) 1969-04-10
GB1039372A (en) 1966-08-17
CH455814A (en) 1968-05-15
BR6347165D0 (en) 1973-07-19
SE312808B (en) 1969-07-28

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