[go: up one dir, main page]

DK0625912T3 - Behandling af inflammatorisk tarmsygdom - Google Patents

Behandling af inflammatorisk tarmsygdom

Info

Publication number
DK0625912T3
DK0625912T3 DK93904830.2T DK93904830T DK0625912T3 DK 0625912 T3 DK0625912 T3 DK 0625912T3 DK 93904830 T DK93904830 T DK 93904830T DK 0625912 T3 DK0625912 T3 DK 0625912T3
Authority
DK
Denmark
Prior art keywords
treatment
inflammatory bowel
bowel disease
tissus
ibd
Prior art date
Application number
DK93904830.2T
Other languages
Danish (da)
English (en)
Inventor
Roy R Lobb
Original Assignee
Biogen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25268692&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0625912(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biogen Inc filed Critical Biogen Inc
Application granted granted Critical
Publication of DK0625912T3 publication Critical patent/DK0625912T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • C07K16/2842Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta1-subunit-containing molecules, e.g. CD29, CD49
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/70542CD106
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK93904830.2T 1992-02-12 1993-02-02 Behandling af inflammatorisk tarmsygdom DK0625912T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US83513992A 1992-02-12 1992-02-12

Publications (1)

Publication Number Publication Date
DK0625912T3 true DK0625912T3 (da) 1997-10-27

Family

ID=25268692

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93904830.2T DK0625912T3 (da) 1992-02-12 1993-02-02 Behandling af inflammatorisk tarmsygdom

Country Status (11)

Country Link
EP (1) EP0625912B1 (fr)
JP (3) JPH07506566A (fr)
AT (1) ATE151642T1 (fr)
AU (1) AU674302B2 (fr)
CA (1) CA2129637C (fr)
DE (1) DE69309906T2 (fr)
DK (1) DK0625912T3 (fr)
ES (1) ES2103468T3 (fr)
GR (1) GR3024041T3 (fr)
HK (1) HK1007683A1 (fr)
WO (1) WO1993015764A1 (fr)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5932214A (en) * 1994-08-11 1999-08-03 Biogen, Inc. Treatment for inflammatory bowel disease with VLA-4 blockers
ATE150975T1 (de) 1992-11-13 1997-04-15 Univ Washington Peripheralisierung hämatopoietischer stammzellen
NZ262615A (en) * 1993-02-09 1996-02-27 Biogen Inc Treating insulin dependent diabetes (type i) with anti vla4 (very late antigen) antibodies
AU727187B2 (en) * 1993-02-09 2000-12-07 Biogen Idec Ma Inc. Treatment for insulin dependent diabetes
ZA947006B (en) * 1993-09-15 1995-05-02 Univ Emory Method of inhibiting binding of reticulocytes to endothelium by interfering with vla-4/vcam-1 interactions
DK1759709T3 (da) * 1994-01-25 2013-06-10 Elan Pharm Inc Humaniserede antistoffer mod leukocytadhæsionsmolekyle VLA-4
US5840299A (en) * 1994-01-25 1998-11-24 Athena Neurosciences, Inc. Humanized antibodies against leukocyte adhesion molecule VLA-4
US7435802B2 (en) 1994-01-25 2008-10-14 Elan Pharaceuticals, Inc. Humanized anti-VLA4 immunoglobulins
US7803904B2 (en) 1995-09-01 2010-09-28 Millennium Pharmaceuticals, Inc. Mucosal vascular addressing and uses thereof
US6551593B1 (en) 1995-02-10 2003-04-22 Millennium Pharmaceuticals, Inc. Treatment of Inflammatory bowel disease by inhibiting binding and/or signalling through α 4 β 7 and its ligands and madcam
US7750137B2 (en) 1995-09-01 2010-07-06 Millennium Pharmaceuticals, Inc. Mucosal vascular addressins
US7147851B1 (en) 1996-08-15 2006-12-12 Millennium Pharmaceuticals, Inc. Humanized immunoglobulin reactive with α4β7 integrin
DE19741235A1 (de) 1997-09-18 1999-03-25 Hoechst Marion Roussel De Gmbh Neue Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
DE19741873A1 (de) * 1997-09-23 1999-03-25 Hoechst Marion Roussel De Gmbh Neue 5-Ring-Heterocyclen, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
DE19751251A1 (de) 1997-11-19 1999-05-20 Hoechst Marion Roussel De Gmbh Substituierte Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmezeutische Präparate
DE19821483A1 (de) 1998-05-14 1999-11-18 Hoechst Marion Roussel De Gmbh Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
DE69940206D1 (de) 1998-09-14 2009-02-12 Univ Texas Verfahren zur behandlung von multiplem myelom und von myelom- induzierter knochenresorption mit antagonisten der integrin-/rezeptorbindung
US7618630B2 (en) 1998-09-14 2009-11-17 Board Of Regents, The University Of Texas System Methods of treating multiple myeloma and myeloma-induced bone resorption using integrin antagonists
DE19922462A1 (de) 1999-05-17 2000-11-23 Aventis Pharma Gmbh Spiro-imidazolidinderivate, ihre Herstellung ihre Verwendung und sie enthaltende pharmazeutische Präparate
DE10111877A1 (de) 2001-03-10 2002-09-12 Aventis Pharma Gmbh Neue Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
DE10137595A1 (de) 2001-08-01 2003-02-13 Aventis Pharma Gmbh Neue Imidazolidinderivate, ihre Herstellung und ihre Verwendung
DE60332093D1 (de) 2002-02-20 2010-05-27 Ajinomoto Kk Neues phenylalaninderivat
DK2336184T3 (en) 2002-02-25 2015-02-16 Biogen Idec Inc Administration of agents for the treatment of inflammation.
EP2803667A1 (fr) 2003-12-22 2014-11-19 Ajinomoto Co., Inc. Dérivés de phenylalanine
CA2714335A1 (fr) 2007-02-20 2008-08-28 Merrimack Pharmaceuticals, Inc. Methodes de traitement de la sclerose en plaques par administration d'une alpha-foetoproteine combinee a un antagoniste de l'integrine
JP4652356B2 (ja) 2007-02-26 2011-03-16 アルプス電気株式会社 ターンシグナルスイッチ装置
CA2721093A1 (fr) 2008-04-11 2009-10-15 Merrimack Pharmaceuticals, Inc. Lieurs d'albumine de serum humain, et ses conjugues
PT2558499T (pt) 2010-04-16 2017-07-14 Biogen Ma Inc Anticorpos anti-vla-4
US10040855B2 (en) 2011-05-02 2018-08-07 Millennium Pharmaceuticals, Inc. Formulation for anti-α4β7 antibody
UA116189C2 (uk) 2011-05-02 2018-02-26 Мілленніум Фармасьютікалз, Інк. КОМПОЗИЦІЯ АНТИ-α4β7 АНТИТІЛА
CN109884295B (zh) * 2017-12-25 2022-03-08 苏州和锐生物科技有限公司 假单胞菌多肽、抗体捕获器件及试剂盒
CN112867394B9 (zh) 2018-06-04 2024-12-06 马萨诸塞州渤健公司 具有降低的效应功能的抗vla-4抗体

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3852374T2 (de) * 1987-11-02 1995-05-04 Baylor College Medicine Verwendung von ICAM-1 oder ihre funktionelle Derivate zur Behandlung unspezifischer Entzündungen.
US5147637A (en) * 1988-06-07 1992-09-15 The Rockefeller University Method of inhibiting the influx of leukocytes into organs during sepsis or other trauma
DK162890D0 (da) 1990-07-06 1990-07-06 Novo Nordisk As Polypeptid
WO1993006864A1 (fr) * 1991-10-01 1993-04-15 The General Hospital Corporation Prevention du rejet d'une allogreffe a l'aide d'anticorps contre des molecules d'adhesion

Also Published As

Publication number Publication date
AU3605993A (en) 1993-09-03
ATE151642T1 (de) 1997-05-15
CA2129637A1 (fr) 1993-08-19
HK1007683A1 (en) 1999-04-23
DE69309906T2 (de) 1997-11-06
JP2004002472A (ja) 2004-01-08
EP0625912B1 (fr) 1997-04-16
JP2007045843A (ja) 2007-02-22
CA2129637C (fr) 1999-05-04
DE69309906D1 (de) 1997-05-22
JPH07506566A (ja) 1995-07-20
JP4108572B2 (ja) 2008-06-25
GR3024041T3 (en) 1997-10-31
ES2103468T3 (es) 1997-09-16
EP0625912A1 (fr) 1994-11-30
AU674302B2 (en) 1996-12-19
WO1993015764A1 (fr) 1993-08-19

Similar Documents

Publication Publication Date Title
DK0625912T3 (da) Behandling af inflammatorisk tarmsygdom
ATE332159T1 (de) System zum sammeln von blut ohne es zu beschädigen
ATE150319T1 (de) Behandlung von asthma
DE69228436D1 (de) Monoklonaler Antikörper, der den C-Terminus von hBNP erkennt
RU95109441A (ru) Способ изготовления целлюлозного волокна и устройство для осуществления способа
ATE250625T1 (de) IM WESENTLICHEN REINES ZONULIN ALS PHYSIOLOGISCHER MODULATOR VON ßTIGHT JUNCTIONSß BEI SÄUGERN
FR2714327B1 (fr) Procédé et appareil de fixation d'un joint sur le bord périphérique d'un article.
CA2034881A1 (fr) Proteine hybride facteur x-laci
EP0937982A3 (fr) Agent diagnostique et thérapeutique pour le traitement de l'hépatite auto-immune
DE69705721D1 (de) Verfahren zur Herstellung von 3-Isochromanon
FR2658197B1 (fr) Anticorps monoclonaux restreints reconnaissant un peptide associe a un antigene du complexe majeur d'histocompatibilite - applications au diagnostic et au traitement.
FI922666A0 (fi) Diagnostiskt foerfarande.
ATE408418T1 (de) Methoden zur inhibition von hiv-assoziierten krankheiten mittels monoklonaler antikörper gegen sich selbstgerichtete zytotoxische t-zellen
FR2710539B1 (fr) Ensemble d'aiguille chirurgicale.
FR2665643B1 (fr) Filtre d'aspiration.
SE8904007D0 (sv) Monoklona antikroppar och diagnostiseringsmetod
DE69434087D1 (de) ENTEROTOXINE VON SHIGELLA FLEXNERI 2a
ES2049021T3 (es) Metodo de recuperar la proteina epi purificada a partir de una solucion, especialmente una solucion de fermentacion.
ATE205529T1 (de) Reninaktive substanz enthaltend humanes prorenin und antikörper gegen das prorenin profragment
DE69825976D1 (de) Verwendung von anti-il-12 antikörpern bei transplantationsabstossungen
DE3850750D1 (de) Verfahren zur Verhütung von GVHD.
RU96109171A (ru) Способ идентификации тела погибшего
FR2737209B1 (fr) Peptide capable d'etre reconnu par des anticorps reconnaissant l'antigene c33 du virus de l'hepatite c
DE69023500D1 (de) Verfahren zum nachweis von antikörpern gegen streptokinase.
ATE231167T1 (de) Pd-ecgf / thymidin phosphorylase spezifischer monoklonaler antikörper