DE7000954U - DEVICE FOR AUTOMATIC TAKING OF LIQUID SAMPLES. - Google Patents

Description

H 12 P 4

PATENT LAWYERS DR. CLAUS REINLANDER DIPL-ENG. KLAUS BERNHARDT

D-β MONK 60

BXCKERSTRASSE 5

PACKARD
Palo Alto, California »

Device for the automatic removal of moisture samples

Ma invention relates to “in” device star automatiachen Withdrawal of liquid from above, and in particular a liquid automatiaoh «device, the gate all in one full * automatic analysis system usable iat and eonohl aar Batep recording is suitable for each »or manual processing is.

Now that the methods have been approved for direct manual analysis using τοη iJae-Cbroniatographtn and other analysis devices, there is more and more correct, semi- and fully automatic systems available for the execution of such analyzes. Two of the other functions for the analyst that co-ordinate the time are the sample injection in the foa-ghroaatograph or another analyzer and the interpretation and quantification of the details. Integrators "Httltipl" zer _t iinalog digital WaEdlar and Jüeehner

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enable considerable savings in the latter areas. However, full automation demands a versatile one Usable, reliable device aur automatic Injection of samples. Such an automatic device must be able to take a precise sample a liquid to be analyzed in a sample container and injected into the analyzer.

In a preferred embodiment, one according to the invention Device for automatic sampling isit a sample transfer device, e.g. Precision Mikrollter syringe mounted in a holder arm » Its first actuating device is designed so that they can move the holding arms along the axis of the syringe cylinder · A second actuating device, the is mounted on the holder arm, actuates the syringe plunger · Its third actuating device moves the first Actuating device and thus the syringe and the second actuating device between a sample receiving point and a sample delivery point. Positioned in the sample holder a large number of separate fluid sample containers. If the successive sample containers are in a sample receiving position are indexed, the automatic device extracts the various by selective excitation Actuating devices a sample from the sample container, shifts the syringe to provide a sample delivery point 9, for example, the injection opening of a Gea chromatograph, and injects the sample at the discharge etelleo

In one embodiment of the invention, each confirmation device digitally excited "so that the goesmt" sampling process under the control of three digital signals a

is performed. The sampling process has a number from individual processes to »for example suction and pump cycles» to flush air bubbles out of the syringe. Ss are different Cycles and poles possible, all under the control of a digital program that is easy to set up or to modify ο

The invention is to be explained in more detail on the basis of an embodiment example shown in the drawing; show it:

1 is a perspective view of a device according to the invention Device for automatic sampling »using a syringe» which is positioned this way « one sample into the injection port of an analyzer is injected »for example a Ges-Chromatographsm;

Pig. 2 shows a side view of the device according to Pig.1 in FIG Buheststellungι

Pig. 3 a plan view of the gate direction after I ¹ Ig ₀ 2;

Pig. 4 a rear view of the device according to Pig. 2 with phantom Representation of part of the rinsing cycle of the syringe;

Pig. 5 a view from below of the circular turntable »in dom the samples are held until positioned;

Pig. 6 with a side view of the device according to Pig.2 Syringe inserted into a sample container?

Pig. 7 shows a partial rear view of the door direction according to the invention in the lag shown in Pig.6;

? ig. β «in« side view of the device according to the invention with the fuel in one position immediately Gate of the sample injection in eiaen Gea-07? Omatogxephen;

Fig. 9 "in" calibration on the device according to Yig · 2 "at

who put the sprits "" in · prob "into the injection opening dee Oae-ChronographeninjiBlert, the mode of operation of the syringe piston β being shown in phantom;

FIG. 10 shows a schematic program sequence of the device operational}

Pig «1OA a sequence diagram in which various possible Loops and sub-loops depicted and that in the Konivoll «of the automatic Voxrlightung of the invention

Pig.lOB a socket for ¹ the a6hfl> maeeichnung ia Pig.iO | other

Pig.11 a block diagram of the digital control system · the sam Operation of the drives of the automatic device according to the invention is used

As can be seen from Pig 1 to 5 , the device for automatic sampling according to the invention is in the form of a detachable unit which can be mounted on the injection port 10 of a general analyzer or the sample inlet in other aiialysis devices for the sake of simplicity the invention is to be described in connection with an Oes-GhrcKBatographaa · Me injection opening of a gas chromatograph is provided with a partition wall

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locked * the ait a Oberfangnutter 14 held will. The Oberfangmutt <ir has a widening opening on, through which the thread 16 of the syringe 18 or another suitable power transmission equipment pass through can. The syringe 18 can be a conventional precision fluid principle * be * never they usually in B gas chromatography can be used. The syringe has a cylinder 20 in which a piston or plunger slidable to ^ brightness by a handle 16 in the Syringe on “live” or “not spray this out”.

The cylinder 20 of the syringe 18 can be in one piece U-shaped holder arm 24 adjustable width to be held The width of the opening See TF-shaped Halterania can be adjusted, for example, using the Yerschiebeglleä 26 »das alt the screw 28 is fixed in a slot 30 (Pig. 4 and 7) fits in sliding element 26. The ("adjustable width is necessary or desirable" around different syringes with different cylinder lengths. When a only syringe should be used »the U-fönaige can EaIterarm 24 consist of one piece o

The upright parts 34 of the TJ-shaped Haltera ras 24 have every concave indentation 35 (Pig.i) on the inner surfaces » to create a set-up level with the bottom of the cylinder 20 can be zoomed in and positioned more safely. The leg 34 of the ϋ-shaped holder arms, which the plunger end positioned »is slotted at 32» so the plunger can be pushed in from the side when the cylinder is being mounted the needle positions its not shown opening on to pick up the ladel 16 that leads through it.

The U-shaped holder arm 24 has a side projection 40 on »

one part of which is bent upwards (? ig.i), so that it » Side arm 42 is formed into a drive or eix »e Actuating device 44 is mounted. It can «was sine any type of drive 44 can be used * however, drives are preferably used with which a linear or sifting movement under the influence of a digital signal is possible. His type of actuator * that has been used with success * is made up of a pneumatic cylinder a cylinder 46 and a piston 48 · the cylinder 46 iet provided with an external thread and attached to the side arm 42, for example with a bolt 50 Oig.4). air, or another fluid «that can be used to actuate the drive 44 su is read out by a Hippel 52. The piston 48 is normally sucked out * as can best be seen in Fig.4, and if he is for example has been actuated with air pressure on the hippel 52, the piston 48 looks into the cylinder 46, as through the Pfatantomllnlen in? Ig «4 is indicated. The drive 44 is spring-loaded * so that * when the air pressure drops «the Piston 48 returns to the sucked-out position, the iii Pig.4- is shown with full lines. Instead of deeaen can also be used in a double acting pneumatic cylinder and then the piston 48 is in both gauges fearfully rubbed

The end of the piston 48 is an L-shaped holder arm 60 " for example with two cutters 62, attached · The L-shaped « Retainer arm 60 extends the length of the side of the cylinder and mounts a clip 64 »der as der Plasgwr ^ Sassss ^ Disk 66 is in contact (best recognizable in Pig * 9) at the end of the plunger 22. The plunger clip 64 is mounted on a box-shaped holder 65 which, by bending, becomes rectangular Sheet metal is formed and from which its side, beieplels wise with a screw * 66 * on a slot 68 in the L-arm

43 \

is attached "As a result, the length of the plunger stroke corresponding to the size of the syringe used .öße ₁ set" ground. The piunger clip 64 consists of a piece of Pedermetal 68 which is attached to the box-shaped holder 65 and bent to accommodate the plunger o The plunger clip 64 is also slotted so that the plunger thumb washer 66 is simply pushed into the clip can be. Other plunger-olip arrangements can be used, for example, the plunger can be attached with a tube that has a hole to receive the plunger and an adjusting screw to hold the rod in place.

In the side arm 42 of the U-arm 24 a screw 70 is inserted, which extends through a slot 72 in the L-arm 60 to facilitate the axial movement (Pig.4) of the L-arm when the drive 44 is actuated. A Handel nut 74, which is screwed onto the screw 70, can be turned to adjust the length of the plunger stroke by limiting the return stroke of the piston. The L-shaped arm 60 has a Voreprung 61 which engages a Pührungsschiltζ 63 in the holder-side arm 40 to prevent rotation of the H _a lter © when it is operated with the plunger drives the 44th

Let the U-arm, which carries the syringe, on the end of the dee Piston 80 of a second actuating device or a drive 82 mounted. The second drive 82 can be in the same Be constructed like the first-mentioned drive 44 and has an input-air-hippel 48, which ensures that the plunger or piston 80 extends linearly out of the cylinder 86 which forms the drive 82. In this way when the second drive of the syringe cylinder 20 is actuated moves along an axis parallel to the axis of the cylinder 20 under the control of a digital input signal which

that excites the drive. Sa the plunger of the drive 62 from U-arm 24 is worn, it also moves for a long time same axis. The plunger 80 of the drive 44 can of course individually energized "earth" via the plunger 22 of the To operate the syringe regardless of the position of the cylinder 20.

The cylinder 86 of the 2 "flashed drive 82 is in turn mounted on a Sghwenkeinhelt _f 90 pivotally seated on a mounting unit 92nd The pivot unit 90 has the general shape of an angled arm with a pivot point 94 through which a pivot rod 96 passes. The swivel rod 96 is attached to an L-flange 98 "which is part of the assembly unit 92" with a bend nut 100 "which is attached to the swivel rod" for example with a single screw. An axially directed pin (not shown) engages the button 100 in a receptacle in the L-Planech 98 to prevent the knob from turning. A coil spring 102 '' which sits over the rod 96 is fastened with one end in a slot in the pivot rod 96 and with the other band "as shown at 104" on the pivot unit 90. Each 102 is so loaded that the Swivel unit 90 in an upright or vertical position »seen in the drawing, in which the cylinders stand upright, borrowed in the drawing ·

The cylinder 110 is one on the lower part of the L-Flanecb.ee 98 Swivel drive 112 (Fig. 2) attached. The swivel drive shows “Inen piston 114” when the drive is energized linearly emerges from the cylinder HO. The piston 114 has, for example, a pin 116 on an arm of the pivot 90 fastened "so there" when the swivel drive 112 excited; "the syringe 18 is from a vertical in" ine horizontal position is pivoted »seen in the drawing

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song Fig.i. The S äiw erikantrieb 112 is spring-loaded, βο that the syringe 18 with the support of the spring 102 normally assumes an upright position, ie the axes of the syringe and the cylinder bind vertically. If air nipples 118 are available on cylinder 110, if the oscillating drive can be energized, "Again, the rotary actuator 112 can be of the same type""ie the drives described.

Am "vertically arranged" Brtthtiech ~ 8ttfts "tange 120 let attached to a longitudinal flange 122 ( ^ν 1 | (· 1 and 3) of the L-flange 98, for example old screws 124. From the L-flange an angle arm 130 is attached, for example A bolt with a knurled Binetellknopf 132 (Fig. 3) · Separately attached to the L-Plariech 98 is an injection opening frame holder arm 134 which has an opening 136 which surrounds the protective mat 14 of the injection opening 134 may have separate adjustment screws, so that it can be set relatively close to the L-Plaueoh, to facilitate the correct adjustment and alignment of the syringe needle 16 with the injection opening. The details of the manner in which the L-flange 98 is mounted -Xlnhelt 92 an analysis instrument is attached, do not form part of the invention, since any suitable device for attaching the membrane to the device can be used in the desired manner. Torcugewel ee the angle arm 130 can be bolted to the instrument housing 12. The described honing unit 92 has a unit which has been used with success and facilitates the quick assembly and flattening of the automatic sampling device. 98 allow · are perhaps aa clearly recognizable in Figo3 and denoted by the reference sign 131 ·

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The illustrated turntable 140 is generally circular in shape and has a circular row of openings 141 Scope on. A complementary shaped container 142 for The liquid sample can be recognized by the test in Pig.6 - is arranged in the openings 141 of the row. Everyone who

Sample container 142 may take the form of a vial with a cap * or partition wall 141 which closes the upper end

I and a flange that the sample container 142

I prevents falling through the slots that form openings 141. A Haltererm 143 · of the rotary table \ montage8tange 120 is mounted attacks on the turntable

f in a position in which the upper edges of the vial

«End walls 144 in the sampling position of the syringe

I covered «ground · This prevents the syringe

; when withdrawing a vial, the vial is displaced.

The openings 141 bind to the outer circumference of the turntable 'open to indexing the turntable with reference to the

\ Syringe 18 to facilitate. Indexing of the turntable

can be brought about in any way, for example with an electric servo motor or another drive

■ mechaniemue, but preferably a digital one j actuator is used, so that the whole thing is automatic

■ working sampling device under the control

■ can work with digital Itt pulses. A preferred digital

■ The actuator for the turntable can best be seen in Fig.'J, ee is an indexing drive 150 in the form

: 'of a pneumatic cylinder with a cylinder 152 * a

r Mppel 154 for admitting gas under pressure, and a

I ben 156 · The piston is attached to an indexing arm 158 with a

The end 160, which is slightly bent inwards, is attached to the In

f each of the exposed circumferential slots dex openings 141

intervenes. Every time the indexing drive 150 (is sjxngt,

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If the indexing arm 16O engages outwards, so that the turntable is rotated gradually in a clockwise direction, it is never indicated by arrow 170 in FIG. The Ipiexierarm 15b is made of spring metal, so that when the spring-loaded piston 156 returns, the indexing arm 136 can only slide over the next position so that it can engage in the next opening when it is called leather aroused. To aid in properly locating the openings 141 with respect to the syringe, a positioning arm 172 is attached to the Ir flange 3Q and has a cylindrical bearing 174 which engages the exposed slot of each of the openings 141 so as to engage the turntable is always indexed or rotated by the correct stride length. The indexing drive 150 is mounted with an arm 176 which is attached to the flange 98 of the mounting unit 92.

The vertical position of the turntable 140 on the turntable mounting rod 120 is determined by several grooves 178 (FIG. 6) in the lower circumference of the mounting rod 120. An adjustment screw 180 can engage in each of these grooves 178. The vertical adjustment of the turntable allows the adjustment on point needles *) of different sizes.

The various drives, including the cylinder drive 82, the plunger drive 64, the swivel drive 112 and the indexing drive 150, which are denoted by the letters A, 5, 0 bss *, are operated separately the respective nipples 84 "52" 200 and 154 are connected. "These nipples are connected by lines not shown to excitation valves V ^, Vg, V" and V _D , which are shown in PIg.11. Those with "to A""to B "," at C "or ⁿ and D" denote lines

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the connection of these lines with the respective drives A, B, Ο * or Γ. These valves, indicated by the blocks with the inscriptions V _A , Vg, V _Q and V ^, supply pressurized gas from a pressurized gas source 202 which is connected by a feed line 24 to the valves V _A , V _B, V _Q and Vpj ^, individually to. Here individual valves

V, V ", Y _n and V _n cookers individually by electric

ABC D

Signals actuated by preferably a control line be derived. In this case, the control source indicated as strip reader 206 can also include one a program read punched strips 206, the control or Control signal «is generated with which valves are individually opened or closed that operate the respective drives. The special programming sequence can easily changed by simply punching a new strip 208 with the desired program, as will be described later.

Other sources of control can also be used if desired »Ee can, for example, be a rotary step switch can be used, or control or control can be obtained directly from a computer instead who also controls the analysis instrumentation.

The operation of the automatic sample injector can be tested in conjunction with Pig. 10, 10A and 10B explained. The three movements of the syringe are shown in Pig * iQA. These three movements are denoted in the following by symbols of Boolean algebra, namely ¹ A "when the injection cylinder drive is actuated, and ⁿ A ⁿ when it is de-excited. Similarly, the operations of the plunger are denoted by the designation" B "' symbolizes when the plunger is withdrawn when

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the valve V _x i is actuated and with "1" if the plunger is depressed when the plunger valve 62 is not actuated. Similarly, the syringe is swiveled clockwise around the pivot point 94 so that it is aligned with the injection opening 10 according to FIG. The pivot point 94 is pivoted so that it comes into a position in which samples can be taken from a sample container when the drive 112 is not energized "S". Finally, the indexer drive 150 is designated by the symbol "D" and turns the turntable clockwise, viewed from above, every time the indexer drive is actuated 10 contains. In this way, the syringe is either pivoted so that it enters the injection port 10, or that it enters a sample container in the sampling point, which is immediately below the syringe when it is in a vertical position.

Using the three basic movements of the syringe, the C are referred to Boole ¹ shear ring with the symbols A, B, or, samples are taken in succession from the various sample containers and ia the injection port 10 of the gas-Ghronatographen or and older analyzer injected . The sequence of these special processes is controlled by digital digits, as shown in Fig. 11, and accordingly the individual movements of the syringe can follow any desired sequence. A typical operational sequence that has long been used to achieve consistency and repeatability of analyzes is shown in Pig. 10

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shown.

Pig. 10 schematically shows the syringe, the cylinder, plunger and needle of which are shown in each of fifteen different steps, starting nobly with block 1 in the upper left corner of the block arrangement, with none of the drives A, B or C being actuated . Each is in the normal or rest position. This original position is the one in which the plunger is depressed and the syringe barrel is in a vertical or upright position, so that it is inserted into a sample container 142 in turntable 140 (Pig. 2) can be. The injection suffix 10 appears in the diagram as a block in the left rope of each of the schematic block representations. The sample container 142 is shown as a box in the lower wire in the center of each S ⁿ hrlttderstellung. When the program paper tape moves forward through the tape reader 206 (Pig.11) 208 "is first sole that valve V ₁ oldbetätigte opened (S _c hritt 2), so that air pressure to the cylinder drive is supplied 62 · The barrel of the syringe 18 then moves downwards so that the syringe needle penetrates the sample container 142. In the third step of the pole, the B drive 46 is excited. The plunger 42 of the syringe 18 is then withdrawn. Pi'obenflüselgkeit is 1st been aspirated from the sample container 142 _v used to the syringe needle.

In the fourth step of this PolgekemäB block 4 "valve V _{A is} closed (A), and the syringe cylinder moves upwards again so that the syringe needle is withdrawn from the sample container 142" This state is shown in Figure 7 of the drawing. Bel Ce «next shrill

000

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the sequence shown in block 5 becomes the B drive de-excited, so that the planger leather is depressed. As a result, the one that has just been withdrawn from the sample container Sample sprayed on the outside of the container cap. That represented by blocks 2-5 The sequence of steps can be repeated as many times as necessary to flush the inside of the syringe, leaving any trace a previous sample is removed. During this Rinsing cycle turns the syringe needle into one at a time Sample container inserted, aas which part of the sample is withdrawn. The needle is then removed from the sample container peeled off and the sample popped out

After the syringe has been sufficiently rinsed., Calls the sixth step of the Polge that the AA _n is excited drive "so that the syringe needle penetrates into the sample container 142 with depressed flask. In step 7 the plunger is pulled out of the syringe by energizing the B drive to ensure that the syringe is free of air bubbles or trapped gases, the plunger is moved back and forth while the syringe needle is in the sample container . This pole is represented by blocks 7, 8 and 9 in PIg.10 and also in Fig. 7, in which the two positions of the plunger are shown in phantom the plunger is withdrawn and depressed in sequence to ensure that a full® volume of sample is withdrawn from the sample vial 142 *

The tenth step in this series of examples is the Plungsr drive A is excited so that the tip needle comes out is drawn from the sample container In step 11 it is

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know that the swivel drive C is now excited, βο that the syringe cylinder is pivoted in its plane, eo that the syringe acb.ee is aligned with the insect ion opening 10 will. In step 12, the Α drive is excited again, so that the syringe cylinder along its new Orientation axis in alignment with the injection port 10 moved forward »so that the needle enters the insect Opening 10 is inserted. In step 13 the plunger drive de-excited so that the plunger is depressed, causing the sample to enter the injection port quickly and safely of the gas chromatograph is injected · The syringe needle is la step 14 with the plunger depressed sucked back again · simply by the cylinder drive A is de-energized · In step 15 the swivel drive is de-energized »so that the sample injector is brought into the boom position shown in block 1 · in which the sprits« has an upright position. i.e. ready to be rinsed are used as preparation for taking the next sample

In this sequence of steps is the puncture of the Indexler drive 150 not shown. This drive will normally excited · after the step 15 has been carried out according to the sequence shown in Pig.10 · The excitation of the indexing drives, which can best be seen in Pig · 3 is, the pivot arm 160 engages in one of the exposed openings 141 and rotates the turntable 140 in the unreeigerslnin at a given angle. At this point the indexing element 172 engages in another opening 141 and data the turntable so that the next sample in the sequence is in the position in which the syringe one Fluid sample can be taken. Desired case can the samples in the turntable are arranged in such a way that an alternating sequence of a sample and then one

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will

Rinsing liquid results. In this sequence / the Indexicr drive

advanced every time after the syringe in any has been rinsed in the desired manner. This rinsing normally takes place after the liquid has been removed from the next sample container.

As appointed "orden ieit, are" was the drives as pneumatic Solenoids have been described · but they also know be operated mechanically or electrically. The pneumatic However, control is preferred because it is continuous Driving force over the entire linear movement of the drive is available.

The design shapes shown in connection with parts i - 11 are suitable for "pivoting the syringe or the other sample transfer mechanism in one plane", which contains the axis of the Spvitsensylindere «Indeed There are many other movements carried out by the three individually actuated actuators according to the invention are «around the axis of the syringe cylinder in different Move as follows »Apart from the mode of operation described in connection with Pig.1-11, the axis of the Syringe cylinders can be moved from one position to another. Another possible design the axis of the syringe cylinder can be paralel about an axis be pivoted to the axis of the syringe cylinder. Every of these embodiments is obtained by changing the manner in which the Sctaienkantrleb C acts on the arm assembly containing the syringe and plunger drive.

A mark «1 of the described device is that so does the arm that carries the syringe barrel itself

, is positioned so that it we driven by a drive r the can, the cylinder-A _n drive which is mounted so as to he shifted da3 with the G-drive
can be. Thus, the syringe and plunger drive are gcibracht in one of two operating positions _t such that they can operate either with the sample container or the Inetrumenteneinlaß. The through the
The degree of movement made possible by the plunger drive is controlled by the adjusting screw 74. This moxitage arrangement allows each of the drives to be operated individually under the control of a digital control signal, so that a large number of different fermentations can be carried out.

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Claims (1)

• I * t f · »Ii »■ - 20 - H 12 P 4 D η sayings Device for the automatic collection of flueaigiraita samples, consisting of a syringe with a cylinder, a plunger and a hollow needle * which is in a longitudinal axis are aligned * a holder arm for the cylinder of the syringe at least one container for a liquid Sample »an injection opening for receiving the sample» a first actuating device with which the arm is displaced along the longitudinal axis, a second actuating device, which is mounted on the arm »to move the plunger relative to the cylinder along the Achue, and a third actuating device with which the erυta actuating device and thus the The holder arm can be moved between two positions, the first being the position of the evacuation of the Syringe with a selected container for liquid I samples corresponds and the second position of the curse I device of the syringe with the injection opening, characterized in that that the syringe is a Prezieiona plushy syringe is and that a device for generating digital signals is provided with the selectively the Displacement devices can be excited in a predetermined Pölgv, so that the precision syringe causes is to transfer liquid from the sample container into the injection port «whereby the excitation device sloe iterative control strip device has, with which the two first-mentioned displacement devices be controlled so that the first dose is taken to the syringe with liquid To flush out of the sample container, a second iterative steaerach loop device is provided »with which the second displacement device is controlled in the first position, so that a repeatable and precisely measured Flue-Bigeevolume is removed from the sample container and a device is provided with which the second displacement device in the second position, the liquid is controlled from the syringe into the injection opening is injected. 2. Device according to "" nspruch 1, characterized in that the container for the liquid sample is sealed with an elastomer material that can be pierced by the needle of the syringe is. 3. Apparatus according to claim 2, characterized in that the first iterative control loop facility has, with which the two displacement devices are digitally controlled ao that they the syringe arm and the Plungers alternate in a sequence for a given number One way len of M _a and fro-moving, so that the Hadel multiple E punctured the elaetomeren completion of the sample container and liquid aud the container transmits, having the second iterative Steuerschleifaneinrichtung means with which the second displacement device is digitally controlled so that the plunger moved back and forth a predetermined number of times, "if the needle is immersed in the liquid in the sample container" and both iterative control loop devices can be operated in a sequence for each sample liquid. 4. Device according spoke 3, characterized in that the Digital control of the first iterative control loop delimitation can be operated in such a way that the plunger is in a position can «ground» within the syringe container before and not after the needle into the sample liquid is immersed, on the contamination of the sample fluid to prevent by any residual liquid, which is retained by a previous sample in the handle. Device according to one of Claims 1 to 4, characterized in that the second displacement device has a device with which the displacement of the plunger and thus the amount of the transferred Fluid is limited ο Device according to claim 5 »characterized in that that the limiting device is adjustable 7. Device according to one of claims 1 to 6, characterized in that each of the displacement devices is a pneumatic cylinder with a drive piston actuated by pneumatic signals is, in particular by pneumatic digital signal · «. 8. Device according to one of claims 1 to 7 with eixter variety of containers for liquid samples and a device with which the containers are held, characterized in that a fourth actuating device is provided with which the container individually in a predetermined sequence with the first Position of the cylinder axis aligned or «brought out of this alignment» , / 23 700Ö954 * #, 2.72 Device according to one of Claims 1-8, characterized in that the third displacement device is the first displacement device in a cylinder axis containing level wasted. Device according to one of Claims 1 to 8, characterized in that that the last-mentioned displacement device ensures that the first-mentioned displacement device rotated around a wide axis parallel to the cylinder axis.