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DE69233234D1 - Genomische hcv-sequenzen für diagnostik und therapie - Google Patents

Genomische hcv-sequenzen für diagnostik und therapie

Info

Publication number
DE69233234D1
DE69233234D1 DE69233234T DE69233234T DE69233234D1 DE 69233234 D1 DE69233234 D1 DE 69233234D1 DE 69233234 T DE69233234 T DE 69233234T DE 69233234 T DE69233234 T DE 69233234T DE 69233234 D1 DE69233234 D1 DE 69233234D1
Authority
DE
Germany
Prior art keywords
diagnostics
therapy
hcv
nucleotide sequence
region
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Revoked
Application number
DE69233234T
Other languages
English (en)
Other versions
DE69233234T2 (de
Inventor
Tai-An Cha
Eileen Beall
Bruce Irvine
Janice Kolberg
S Urdea
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Vaccines and Diagnostics Inc
Original Assignee
Chiron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24800701&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69233234(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Chiron Corp filed Critical Chiron Corp
Publication of DE69233234D1 publication Critical patent/DE69233234D1/de
Application granted granted Critical
Publication of DE69233234T2 publication Critical patent/DE69233234T2/de
Anticipated expiration legal-status Critical
Revoked legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/162—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/706—Specific hybridization probes for hepatitis
    • C12Q1/707—Specific hybridization probes for hepatitis non-A, non-B Hepatitis, excluding hepatitis D
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Reproductive Health (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Endocrinology (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
DE69233234T 1991-05-08 1992-05-08 Genomische hcv-sequenzen für diagnostik und therapie Revoked DE69233234T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US69732691A 1991-05-08 1991-05-08
US697326 1991-05-08
PCT/US1992/004036 WO1992019743A2 (en) 1991-05-08 1992-05-08 Hcv genomic sequences for diagnostics and therapeutics

Publications (2)

Publication Number Publication Date
DE69233234D1 true DE69233234D1 (de) 2003-12-04
DE69233234T2 DE69233234T2 (de) 2004-08-05

Family

ID=24800701

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69233234T Revoked DE69233234T2 (de) 1991-05-08 1992-05-08 Genomische hcv-sequenzen für diagnostik und therapie

Country Status (20)

Country Link
EP (2) EP1394256A3 (de)
JP (7) JPH06508026A (de)
KR (1) KR100193801B1 (de)
AT (1) ATE252154T1 (de)
BG (3) BG62142B1 (de)
CA (1) CA2108466C (de)
CZ (2) CZ288720B6 (de)
DE (1) DE69233234T2 (de)
DK (1) DK0585398T3 (de)
ES (1) ES2207633T3 (de)
FI (1) FI115725B (de)
HU (1) HU227548B1 (de)
IE (1) IE921482A1 (de)
NO (1) NO309532B1 (de)
PL (2) PL169880B1 (de)
PT (1) PT100472B (de)
RO (1) RO117267B1 (de)
RU (1) RU2155228C2 (de)
SK (1) SK284205B6 (de)
WO (1) WO1992019743A2 (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5428145A (en) * 1991-08-09 1995-06-27 Immuno Japan, Inc. Non-A, non-B, hepatitis virus genome, polynucleotides, polypeptides, antigen, antibody and detection systems
EP0532167A3 (en) * 1991-08-09 1993-03-31 Immuno Japan Inc. Non-a, non-b hepatitis virus genome, polynucleotides, polypeptides, antigen, antibody and detection systems
EP0532258A2 (de) * 1991-09-09 1993-03-17 Immuno Japan Inc. Oligonukleotide und Verfahren zum Nachweis von HCV-Gentypen
DE610436T1 (de) * 1991-11-21 1995-08-03 Common Services Agency Detektion des Hepatis-C Virus.
US6709828B1 (en) 1992-03-06 2004-03-23 N.V. Innogenetics S.A. Process for the determination of peptides corresponding to immunologically important epitopes and their use in a process for determination of antibodies or biotinylated peptides corresponding to immunologically important epitopes, a process for preparing them and compositions containing them
US6667387B1 (en) 1996-09-30 2003-12-23 N.V. Innogenetics S.A. HCV core peptides
EP1262560A2 (de) * 1992-05-29 2002-12-04 Abbott Laboratories Methode zur Herstellung von cDNA ausgehend von einer RNA Zielsequenz in einer Probe
CA2143678A1 (en) * 1992-09-10 1994-03-17 Kevin P. Anderson Compositions and methods for treatment of hepatitis c virus-associated diseases
US6423489B1 (en) * 1992-09-10 2002-07-23 Isis Pharmaceuticals, Inc. Compositions and methods for treatment of Hepatitis C virus-associated diseases
JPH06153961A (ja) * 1992-11-27 1994-06-03 Imuno Japan:Kk Ｃ型肝炎ウイルス部分遺伝子、ならびにｃ型肝炎ウイルス遺 伝子の高感度検出法
US7258977B1 (en) 1992-11-27 2007-08-21 Innogenetics N.V. Process for typing of HCV isolates
DE69324678T2 (de) 1992-11-27 1999-12-09 Naamloze Vennootschap Innogenetics S.A., Gent Verfahren zur typisierung von hcv-isolaten
WO1994025601A2 (en) 1993-04-27 1994-11-10 N.V. Innogenetics S.A. New sequences of hepatitis c virus genotypes and their use as therapeutic and diagnostic agents
US7255997B1 (en) 1993-04-27 2007-08-14 N.V. Innogenetics S.A. Sequences of hepatitis C virus genotypes and their use as therapeutic and diagnostic agents
JPH0775585A (ja) * 1993-06-14 1995-03-20 Immuno Japan:Kk Ｃ型肝炎ウイルス関連オリゴヌクレオチドならびにｃ型肝炎 ウイルス遺伝子型判定方法
US7070790B1 (en) 1993-06-29 2006-07-04 The United States Of America As Represented By The Department Of Health And Human Services Nucleotide and deduced amino acid sequences of the envelope 1 and core genes of isolates of hepatitis C virus and the use of reagents derived from these sequences in diagnostic methods and vaccines
US5514539A (en) * 1993-06-29 1996-05-07 The United States Of America As Represented By The Department Of Health And Human Services Nucleotide and deduced amino acid sequences of the envelope 1 gene of 51 isolates of hepatitis C virus and the use of reagents derived from these sequences in diagnostic methods and vaccines
US5882852A (en) * 1993-06-29 1999-03-16 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Hepatitic C virus (HCV) core gene nucleotide sequences and related methods of detecting major and minor genotypes of HCV isolates
WO1995011918A1 (en) * 1993-10-29 1995-05-04 Srl, Inc. Antigen peptide compound and immunoassay method
EP0759979A4 (de) * 1994-05-10 1999-10-20 Gen Hospital Corp Die antisense-inhibition des hepatitis c virus
CA2201703A1 (en) 1994-10-21 1996-05-09 Geert Maertens New sequences of hepatitis c virus genotypes and their use as prophylactic, therapeutic and diagnostic agents
US5851759A (en) * 1996-04-19 1998-12-22 Chiron Corporation Heteroduplex tracking assay (HTA) for genotyping HCV
IT1284847B1 (it) * 1996-06-07 1998-05-22 Sorin Biomedica Diagnostics Sp Procedimento per la rivelazione di acidi nucleici specifici di hcv
WO1999023250A2 (de) * 1997-11-04 1999-05-14 Roche Diagnostics Gmbh Spezifisches und sensitives nukleinsäurenachweisverfahren
US6680059B2 (en) 2000-08-29 2004-01-20 Tripep Ab Vaccines containing ribavirin and methods of use thereof
JP5175417B2 (ja) 2000-08-17 2013-04-03 トリペップ アクチ ボラゲット リバビリンを含むワクチンおよびその使用方法
US7022830B2 (en) 2000-08-17 2006-04-04 Tripep Ab Hepatitis C virus codon optimized non-structural NS3/4A fusion gene
US6858590B2 (en) 2000-08-17 2005-02-22 Tripep Ab Vaccines containing ribavirin and methods of use thereof
US6586584B2 (en) 2001-01-29 2003-07-01 Becton, Dickinson And Company Sequences and methods for detection of Hepatitis C virus
US7196183B2 (en) 2001-08-31 2007-03-27 Innogenetics N.V. Hepatitis C virus genotype, and its use as prophylactic, therapeutic and diagnostic agent
US8124747B2 (en) 2003-08-29 2012-02-28 Innogenetics HCV clade and prototype sequences thereof
WO2005067643A2 (en) 2004-01-07 2005-07-28 Third Wave Technologies, Inc. Determination of hepatitis c virus genotype
KR100733186B1 (ko) * 2005-05-31 2007-06-27 재단법인 목암생명공학연구소 Ｈｃｖ 유전자에 특이적인 작은 간섭 ｒｎａ 및 그를유효성분으로 포함하는 ｃ형 간염 치료제
WO2009022236A2 (en) 2007-08-16 2009-02-19 Tripep Ab Immunogen platform

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3886363T3 (de) * 1987-11-18 2004-09-09 Chiron Corp. (N.D.Ges.D. Staates Delaware), Emeryville NANBV-Diagnostika
SU1645302A1 (ru) * 1989-01-05 1991-04-30 Московский Научно-Исследовательский Институт Педиатрии И Детской Хирургии Минздрава Рсфср Способ дифференциальной индикации вирусспецифических нуклеотидных последовательностей вируса герпеса простого типа 1 и 2.
UA50829C2 (uk) * 1989-03-17 2002-11-15 Чірон Корпорейшн Очищений поліпептид, що містить антиген вірусу гепатиту с, полінуклеотид, вектор, клітини, система експресії, моноклональне антитіло, препарат поліклональних антитіл, нуклеотидна проба, аналітичні набори, спосіб виявлення нуклеїнових кислот, способи імуноаналізу, вакцина, спосіб одержання антитіл
AU642942B2 (en) * 1989-12-18 1993-11-04 Wellcome Foundation Limited, The Viral agent
WO1991014779A1 (fr) * 1990-03-28 1991-10-03 Mitsui Toatsu Chemicals, Incorporated Diagnostic du virus de l'hepatite
EP0527815B1 (de) * 1990-04-06 2000-07-19 Genelabs Technologies, Inc. Hepatitis c-virus-epitope
NZ238681A (en) * 1990-06-25 1992-03-26 Univ Osaka Res Found Non-a, non-b hepatitis virus particles and their production
EP0933426A1 (de) * 1990-06-25 1999-08-04 The Research Foundation for Microbial Diseases of Osaka University Non-A, Non-B Hepatitis Virus genomisches DNS und Antigenpolypeptide
EP0510952A1 (de) * 1991-04-26 1992-10-28 Immuno Japan Inc. Oligonukleotid-Primer und ihre Anwendung zum Nachweis von Non-A, Non-B-Hepatitis mit höchster Genauigkeit

Also Published As

Publication number Publication date
JP2003009893A (ja) 2003-01-14
NO309532B1 (no) 2001-02-12
RO117267B1 (ro) 2001-12-28
JP2003009891A (ja) 2003-01-14
CZ288722B6 (cs) 2001-08-15
CZ288720B6 (cs) 2001-08-15
CA2108466C (en) 2007-07-10
FI934937L (fi) 1994-01-05
PT100472B (pt) 1999-08-31
EP0585398A1 (de) 1994-03-09
PL169880B1 (pl) 1996-09-30
JP2003009892A (ja) 2003-01-14
CZ121096A3 (en) 1996-08-14
SK284205B6 (sk) 2004-10-05
HU9303166D0 (en) 1994-03-28
BG101876A (en) 1998-11-30
WO1992019743A2 (en) 1992-11-12
RU2155228C2 (ru) 2000-08-27
ATE252154T1 (de) 2003-11-15
SK123293A3 (en) 1994-06-08
KR100193801B1 (ko) 1999-06-15
BG62142B1 (bg) 1999-03-31
JPH06508026A (ja) 1994-09-14
NO934019D0 (no) 1993-11-05
BG98200A (bg) 1995-01-31
CA2108466A1 (en) 1992-11-09
ES2207633T3 (es) 2004-06-01
CZ237793A3 (en) 1994-04-13
FI115725B (fi) 2005-06-30
HUT69609A (en) 1995-09-28
EP1394256A3 (de) 2008-03-12
PT100472A (pt) 1993-08-31
PL170151B1 (pl) 1996-10-31
DK0585398T3 (da) 2004-02-02
WO1992019743A3 (en) 1993-11-25
JP2008178416A (ja) 2008-08-07
AU2155892A (en) 1992-12-21
JP2003024090A (ja) 2003-01-28
FI934937A0 (fi) 1993-11-08
JP2004290204A (ja) 2004-10-21
EP0585398B1 (de) 2003-10-15
NO934019L (no) 1993-11-05
BG64627B1 (bg) 2005-09-30
DE69233234T2 (de) 2004-08-05
EP1394256A2 (de) 2004-03-03
HU227548B1 (en) 2011-08-29
IE921482A1 (en) 1992-11-18
AU668355B2 (en) 1996-05-02

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8331 Complete revocation
8327 Change in the person/name/address of the patent owner

Owner name: NOVARTIS VACCINES AND DIAGNOSTICS,INC.(N.D.GES, US