DE69213207D1 - Verfahren zur haaranalyse - Google Patents
Verfahren zur haaranalyseInfo
- Publication number
- DE69213207D1 DE69213207D1 DE69213207T DE69213207T DE69213207D1 DE 69213207 D1 DE69213207 D1 DE 69213207D1 DE 69213207 T DE69213207 T DE 69213207T DE 69213207 T DE69213207 T DE 69213207T DE 69213207 D1 DE69213207 D1 DE 69213207D1
- Authority
- DE
- Germany
- Prior art keywords
- sample
- keratin
- enzyme
- proteinase
- analyte
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000000034 method Methods 0.000 title abstract 3
- 231100000640 hair analysis Toxicity 0.000 title 1
- 102000011782 Keratins Human genes 0.000 abstract 5
- 108010076876 Keratins Proteins 0.000 abstract 5
- 108090000790 Enzymes Proteins 0.000 abstract 3
- 102000004190 Enzymes Human genes 0.000 abstract 3
- 229940088598 enzyme Drugs 0.000 abstract 3
- 108091005804 Peptidases Proteins 0.000 abstract 2
- 102000035195 Peptidases Human genes 0.000 abstract 2
- 239000012491 analyte Substances 0.000 abstract 2
- 238000004458 analytical method Methods 0.000 abstract 2
- 239000003599 detergent Substances 0.000 abstract 2
- 230000029087 digestion Effects 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 235000019833 protease Nutrition 0.000 abstract 2
- PSBDWGZCVUAZQS-UHFFFAOYSA-N (dimethylsulfonio)acetate Chemical compound C[S+](C)CC([O-])=O PSBDWGZCVUAZQS-UHFFFAOYSA-N 0.000 abstract 1
- KWIUHFFTVRNATP-UHFFFAOYSA-N Betaine Natural products C[N+](C)(C)CC([O-])=O KWIUHFFTVRNATP-UHFFFAOYSA-N 0.000 abstract 1
- 108090001069 Chymopapain Proteins 0.000 abstract 1
- 108010067770 Endopeptidase K Proteins 0.000 abstract 1
- 108010059378 Endopeptidases Proteins 0.000 abstract 1
- 102000005593 Endopeptidases Human genes 0.000 abstract 1
- KWIUHFFTVRNATP-UHFFFAOYSA-O N,N,N-trimethylglycinium Chemical compound C[N+](C)(C)CC(O)=O KWIUHFFTVRNATP-UHFFFAOYSA-O 0.000 abstract 1
- 108090000526 Papain Proteins 0.000 abstract 1
- 239000004365 Protease Substances 0.000 abstract 1
- ISWQCIVKKSOKNN-UHFFFAOYSA-L Tiron Chemical compound [Na+].[Na+].OC1=CC(S([O-])(=O)=O)=CC(S([O-])(=O)=O)=C1O ISWQCIVKKSOKNN-UHFFFAOYSA-L 0.000 abstract 1
- 239000012190 activator Substances 0.000 abstract 1
- 229960003237 betaine Drugs 0.000 abstract 1
- 239000003613 bile acid Substances 0.000 abstract 1
- 230000015556 catabolic process Effects 0.000 abstract 1
- 229960002976 chymopapain Drugs 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- ARUVKPQLZAKDPS-UHFFFAOYSA-L copper(II) sulfate Chemical compound [Cu+2].[O-][S+2]([O-])([O-])[O-] ARUVKPQLZAKDPS-UHFFFAOYSA-L 0.000 abstract 1
- 229910000366 copper(II) sulfate Inorganic materials 0.000 abstract 1
- 238000006731 degradation reaction Methods 0.000 abstract 1
- VHJLVAABSRFDPM-ZXZARUISSA-N dithioerythritol Chemical compound SC[C@H](O)[C@H](O)CS VHJLVAABSRFDPM-ZXZARUISSA-N 0.000 abstract 1
- VHJLVAABSRFDPM-QWWZWVQMSA-N dithiothreitol Chemical compound SC[C@@H](O)[C@H](O)CS VHJLVAABSRFDPM-QWWZWVQMSA-N 0.000 abstract 1
- 210000004905 finger nail Anatomy 0.000 abstract 1
- 229940055729 papain Drugs 0.000 abstract 1
- 235000019834 papain Nutrition 0.000 abstract 1
- 238000003127 radioimmunoassay Methods 0.000 abstract 1
- 229940117986 sulfobetaine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/40—Concentrating samples
- G01N1/405—Concentrating samples by adsorption or absorption
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
- G01N33/948—Sedatives, e.g. cannabinoids, barbiturates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/40—Concentrating samples
- G01N1/4044—Concentrating samples by chemical techniques; Digestion; Chemical decomposition
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N2001/002—Devices for supplying or distributing samples to an analysing apparatus
- G01N2001/007—Devices specially adapted for forensic samples, e.g. tamper-proofing, sample tracking
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4742—Keratin; Cytokeratin
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
- G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
- G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
- G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
- G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
- G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
- G01N2333/96433—Serine endopeptidases (3.4.21)
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/815—Test for named compound or class of compounds
- Y10S436/816—Alkaloids, amphetamines, and barbiturates
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/825—Pretreatment for removal of interfering factors from sample
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/901—Drugs of abuse, e.g. narcotics, amphetamine
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25125—Digestion or removing interfering materials
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Anesthesiology (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Cosmetics (AREA)
- Sampling And Sample Adjustment (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/737,703 US6949344B1 (en) | 1987-12-28 | 1991-07-30 | Hair analysis method |
| PCT/US1992/006337 WO1993003368A1 (en) | 1991-07-30 | 1992-07-30 | Hair analysis method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE69213207D1 true DE69213207D1 (de) | 1996-10-02 |
Family
ID=24964952
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69213207T Expired - Lifetime DE69213207D1 (de) | 1991-07-30 | 1992-07-30 | Verfahren zur haaranalyse |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US6949344B1 (de) |
| EP (1) | EP0555440B1 (de) |
| JP (1) | JP3229320B2 (de) |
| AT (1) | ATE142020T1 (de) |
| CA (1) | CA2092917C (de) |
| DE (1) | DE69213207D1 (de) |
| WO (1) | WO1993003368A1 (de) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5466579A (en) * | 1987-12-28 | 1995-11-14 | Psychemedics Corporation | Hair analysis method |
| DE19835055A1 (de) * | 1998-08-04 | 2000-02-24 | Wella Ag | Verfahren zur Bestimmung des Zustandes von Haaren sowie hierfür geeignete Vorrichtungen und Mittel |
| IT1309450B1 (it) * | 1999-07-20 | 2002-01-23 | Azienda Provinciale Per I Serv | Procedimento per la determinazione quantitativa di cocaina ed altresostanze similari presenti in un campione ottenuto partendo da un |
| JP2008232674A (ja) * | 2007-03-16 | 2008-10-02 | National Research Institute Of Police Science Japan | 毛髪中に蓄積された化学物質の抽出方法と分析方法 |
| US8084215B2 (en) | 2008-04-29 | 2011-12-27 | Psychemedics Corporation | Non-proteolytic method for the determination of analytes in keratinized structures |
| BRPI0911552B8 (pt) * | 2008-04-29 | 2021-07-27 | Psychemedics Corp | métodos para determinar a presença de um analito de interesse, e de uma pluralidade de analitos de interesse diferentes, e, composição |
| DK2313776T3 (da) | 2008-07-09 | 2014-01-27 | Inst Ethnomedicine | Immunoassay til detektion af neurotoksisk aminosyre forbundet med neurologiske sygdomme |
| CA2794248C (en) * | 2010-03-24 | 2018-02-20 | Glendon John Parker | Methods for conducting genetic analysis using protein polymorphisms |
| BR112014032907A2 (pt) | 2012-06-28 | 2017-06-27 | Psychemedics Corp | detecção de analitos em amostras de lavagem de cabelo |
| EP3039432B1 (de) | 2013-08-28 | 2019-10-09 | Psychemedics Corporation | Unversehrtheitsprüfung von haarproben |
| CN104422607A (zh) * | 2013-09-05 | 2015-03-18 | 杭州优玛达生物科技有限公司 | 一种毛发的前处理方法 |
| KR101374193B1 (ko) * | 2013-09-17 | 2014-03-14 | 대한민국 | 면역 반응 측정법을 이용한 모발 중 마약 성분 신속 분석법 |
| JP7195847B2 (ja) * | 2017-10-02 | 2022-12-26 | アークレイ株式会社 | 糖化蛋白質の測定 |
| CN113341135A (zh) * | 2018-07-30 | 2021-09-03 | 杭州莱和生物技术有限公司 | 一种荧光免疫检测毛发痕量毒品的试剂盒及其图像检测方法与系统 |
| CN112198315B (zh) * | 2020-09-11 | 2023-10-27 | 杭州奥泰生物技术股份有限公司 | 一种采集及检测指甲或趾甲样本中滥用药物的方法 |
| CN113607521B (zh) * | 2021-08-02 | 2024-02-09 | 中国刑事警察学院 | 一种科研用药品/毒品阳性毛发的制备方法 |
| CN115060562B (zh) * | 2022-06-27 | 2023-05-05 | 上海凯创生物技术有限公司 | 一种毛发毒品痕量检测提取液及其制备、使用方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5772009A (en) * | 1980-08-29 | 1982-05-06 | Aisin Seiki Co Ltd | Sensor for rotating angle |
| US5288611A (en) * | 1983-01-10 | 1994-02-22 | Gen-Probe Incorporated | Method for detecting, identifying, and quantitating organisms and viruses |
| US4939240A (en) * | 1983-03-04 | 1990-07-03 | Health Research, Inc. | Monoclonal antibodies to human breast carcinoma cells and their use in diagnosis and therapy |
| US4762706A (en) * | 1984-10-17 | 1988-08-09 | Cetus Corporation | Peptide antibodies and their use in detecting oncogene products |
| US4853335A (en) * | 1987-09-28 | 1989-08-01 | Olsen Duane A | Colloidal gold particle concentration immunoassay |
| CA2004068C (en) * | 1988-12-16 | 2001-06-19 | Werner A. Baumgartner | Hair analysis method |
| JP2837921B2 (ja) * | 1990-05-22 | 1998-12-16 | サイケメディクス コーポレイション | 毛髪分析法 |
-
1991
- 1991-07-30 US US07/737,703 patent/US6949344B1/en not_active Expired - Lifetime
-
1992
- 1992-07-30 DE DE69213207T patent/DE69213207D1/de not_active Expired - Lifetime
- 1992-07-30 JP JP50373293A patent/JP3229320B2/ja not_active Expired - Lifetime
- 1992-07-30 AT AT92917839T patent/ATE142020T1/de not_active IP Right Cessation
- 1992-07-30 EP EP92917839A patent/EP0555440B1/de not_active Expired - Lifetime
- 1992-07-30 WO PCT/US1992/006337 patent/WO1993003368A1/en not_active Ceased
- 1992-07-30 CA CA002092917A patent/CA2092917C/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US6949344B1 (en) | 2005-09-27 |
| EP0555440A4 (de) | 1994-03-23 |
| CA2092917A1 (en) | 1993-01-31 |
| EP0555440A1 (de) | 1993-08-18 |
| ATE142020T1 (de) | 1996-09-15 |
| WO1993003368A1 (en) | 1993-02-18 |
| JP3229320B2 (ja) | 2001-11-19 |
| JPH06503424A (ja) | 1994-04-14 |
| CA2092917C (en) | 2002-06-25 |
| EP0555440B1 (de) | 1996-08-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8332 | No legal effect for de |