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DE69200474D1 - Verfahren zur herstellung einer festem pharmazeutischen zusammensetzung. - Google Patents

Verfahren zur herstellung einer festem pharmazeutischen zusammensetzung.

Info

Publication number
DE69200474D1
DE69200474D1 DE69200474T DE69200474T DE69200474D1 DE 69200474 D1 DE69200474 D1 DE 69200474D1 DE 69200474 T DE69200474 T DE 69200474T DE 69200474 T DE69200474 T DE 69200474T DE 69200474 D1 DE69200474 D1 DE 69200474D1
Authority
DE
Germany
Prior art keywords
polymer
amorphous
solid pharmaceutical
finely divided
substantially amorphous
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69200474T
Other languages
English (en)
Other versions
DE69200474T2 (de
Inventor
Thomas Molloy
David Lee
Sham Chopra
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline Inc
Original Assignee
Glaxo Canada Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB919100040A external-priority patent/GB9100040D0/en
Priority claimed from GB919117525A external-priority patent/GB9117525D0/en
Application filed by Glaxo Canada Inc filed Critical Glaxo Canada Inc
Publication of DE69200474D1 publication Critical patent/DE69200474D1/de
Application granted granted Critical
Publication of DE69200474T2 publication Critical patent/DE69200474T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69200474T 1991-01-03 1992-01-03 Verfahren zur herstellung einer festem pharmazeutischen zusammensetzung. Expired - Fee Related DE69200474T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB919100040A GB9100040D0 (en) 1991-01-03 1991-01-03 Process
GB919117525A GB9117525D0 (en) 1991-08-14 1991-08-14 Process
PCT/CA1992/000004 WO1992011845A1 (en) 1991-01-03 1992-01-03 Method for production of solid pharmaceutical preparation

Publications (2)

Publication Number Publication Date
DE69200474D1 true DE69200474D1 (de) 1994-11-03
DE69200474T2 DE69200474T2 (de) 1995-02-02

Family

ID=26298203

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69200474T Expired - Fee Related DE69200474T2 (de) 1991-01-03 1992-01-03 Verfahren zur herstellung einer festem pharmazeutischen zusammensetzung.

Country Status (8)

Country Link
EP (1) EP0565560B1 (de)
JP (1) JPH06504276A (de)
AT (1) ATE112163T1 (de)
AU (1) AU657514B2 (de)
CA (1) CA2100272A1 (de)
DE (1) DE69200474T2 (de)
ES (1) ES2060465T3 (de)
WO (1) WO1992011845A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0620728B1 (de) * 1992-01-13 1997-01-08 Pfizer Inc. Verfahren zur herstellung von tabletten mit hoher festigkeit
US5358502A (en) * 1993-02-25 1994-10-25 Pfizer Inc PH-triggered osmotic bursting delivery devices
US5536505A (en) * 1993-12-15 1996-07-16 Eastman Chemical Company Controlled release matrix system using cellulose acetate/poly-2-ethyl-2-oxazoline blends
US5523095A (en) * 1993-12-15 1996-06-04 Eastman Chemical Company Controlled release matrix system using cellulose acetate/polyvinylpyrrolidone blends
DE29502547U1 (de) * 1995-02-16 1995-03-30 Röhm GmbH, 64293 Darmstadt Thermoplastisches Überzugs- und Bindemittel für Arzneiformen
JP3471977B2 (ja) * 1995-06-02 2003-12-02 信越化学工業株式会社 液体状可塑剤を用いる無溶媒腸溶性コーティング剤で被覆した腸溶性製剤
AU6403196A (en) * 1995-06-30 1997-02-05 Baylor University Polyester/carboxylic acid composite materials
US6051607A (en) * 1998-07-02 2000-04-18 Micro Therapeutics, Inc. Vascular embolizing compositions comprising ethyl lactate and methods for their use
DE10114247A1 (de) * 2001-03-22 2002-10-10 Heraeus Kulzer Gmbh & Co Kg Antibiotikum-/Antibiotika-Polymer-Kombination
JP4790597B2 (ja) 2003-04-24 2011-10-12 ヤゴテック アーゲー 規定されたコア幾何学的配置を有する遅延放出錠
EP2049123B2 (de) 2006-08-03 2016-08-24 Horizon Pharma AG Behandlung von rheumatoiden erkrankungen mit einem glucocorticoid mit verzögerter freisetzung
CN106748819A (zh) * 2016-11-21 2017-05-31 河南工业大学 沙丁胺醇苯甲酸盐的制备方法及其晶体结构
CN106748824A (zh) * 2016-11-21 2017-05-31 河南工业大学 一种新的沙丁胺醇药物盐‑沙丁胺醇富马酸盐及其制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2841528A (en) * 1954-09-21 1958-07-01 Collett & Co As Method of making fused tablets
US2852433A (en) * 1956-03-07 1958-09-16 Eastman Kodak Co Method of making enteric medicament compositions
US3325365A (en) * 1963-04-02 1967-06-13 Ciba Geigy Corp Enteric composition for tablet compression coating
JPS5855125B2 (ja) * 1980-03-10 1983-12-08 信越化学工業株式会社 固形薬剤用腸溶性コ−テイング剤組成物
JPS57171428A (en) * 1981-04-13 1982-10-22 Sankyo Co Ltd Preparation of coated solid preparation
JPS6051124A (ja) * 1983-08-31 1985-03-22 Kohjin Co Ltd 腸溶性材コ−ティング液
US4716041A (en) * 1984-02-10 1987-12-29 A/S Alfred Benzon Diffusion coated multiple-units dosage form
HU191246B (en) * 1984-02-21 1987-01-28 Alkaloida Vegyeszeti Gyara,Hu Process for producing oral pharmaceutical compositions of retaed activity
GB2170104A (en) * 1985-01-30 1986-07-30 Warner Lambert Co Coated pharmaceutical dosage forms
GB8820353D0 (en) * 1988-08-26 1988-09-28 Staniforth J N Controlled release tablet

Also Published As

Publication number Publication date
JPH06504276A (ja) 1994-05-19
CA2100272A1 (en) 1992-07-04
WO1992011845A1 (en) 1992-07-23
ES2060465T3 (es) 1994-11-16
EP0565560B1 (de) 1994-09-28
AU1158792A (en) 1992-08-17
AU657514B2 (en) 1995-03-16
ATE112163T1 (de) 1994-10-15
EP0565560A1 (de) 1993-10-20
DE69200474T2 (de) 1995-02-02

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee