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DE69133314D1 - Aerosolzubereitungen zur dosierten Abgabe - Google Patents

Aerosolzubereitungen zur dosierten Abgabe

Info

Publication number
DE69133314D1
DE69133314D1 DE69133314T DE69133314T DE69133314D1 DE 69133314 D1 DE69133314 D1 DE 69133314D1 DE 69133314 T DE69133314 T DE 69133314T DE 69133314 T DE69133314 T DE 69133314T DE 69133314 D1 DE69133314 D1 DE 69133314D1
Authority
DE
Germany
Prior art keywords
aerosol preparations
metered delivery
metered
delivery
aerosol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69133314T
Other languages
English (en)
Inventor
Robert K Schultz
Stephen N Quessy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
3M Co
Original Assignee
Minnesota Mining and Manufacturing Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Minnesota Mining and Manufacturing Co filed Critical Minnesota Mining and Manufacturing Co
Application granted granted Critical
Publication of DE69133314D1 publication Critical patent/DE69133314D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/12Aerosols; Foams
    • A61K9/124Aerosols; Foams characterised by the propellant
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Nanotechnology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Otolaryngology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69133314T 1990-03-23 1991-03-22 Aerosolzubereitungen zur dosierten Abgabe Expired - Lifetime DE69133314D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US49833390A 1990-03-23 1990-03-23

Publications (1)

Publication Number Publication Date
DE69133314D1 true DE69133314D1 (de) 2003-10-23

Family

ID=23980625

Family Applications (3)

Application Number Title Priority Date Filing Date
DE69131867T Expired - Fee Related DE69131867T2 (de) 1990-03-23 1991-03-22 Anwendung von löslichen fluorhaltigen Tensiden zur Herstellung von Aerosol-Präparaten mit dosierter Abgabe
DE69133314T Expired - Lifetime DE69133314D1 (de) 1990-03-23 1991-03-22 Aerosolzubereitungen zur dosierten Abgabe
DE69109284T Expired - Fee Related DE69109284T2 (de) 1990-03-23 1991-03-22 Verwendung von fluorierten löslichen tensiden zur herstellung von aerosolarzneimitteln mit dosierter abgabe.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE69131867T Expired - Fee Related DE69131867T2 (de) 1990-03-23 1991-03-22 Anwendung von löslichen fluorhaltigen Tensiden zur Herstellung von Aerosol-Präparaten mit dosierter Abgabe

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69109284T Expired - Fee Related DE69109284T2 (de) 1990-03-23 1991-03-22 Verwendung von fluorierten löslichen tensiden zur herstellung von aerosolarzneimitteln mit dosierter abgabe.

Country Status (7)

Country Link
EP (3) EP0526481B1 (de)
JP (1) JPH05505824A (de)
AU (1) AU654813B2 (de)
CA (1) CA2077354A1 (de)
DE (3) DE69131867T2 (de)
ES (1) ES2071306T3 (de)
WO (1) WO1991014422A1 (de)

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US5126123A (en) * 1990-06-28 1992-06-30 Glaxo, Inc. Aerosol drug formulations
IE912246A1 (en) * 1990-06-28 1992-01-01 Glaxo Inc Aerosol drug formulations
US5785952A (en) * 1990-11-09 1998-07-28 Glaxo Group Limited Aerosol medicament formulation having a surface coating of surfactant
ATE134509T1 (de) * 1991-06-10 1996-03-15 Schering Corp Fluorchlorkohlenwasserstoffreie aerosolformulierungen
HUT67445A (en) 1991-06-10 1995-04-28 Schering Corp Aerosol formulations containing 1,1,1,2-tetrafluorethane
DE4123663A1 (de) * 1991-07-17 1993-01-21 Schwabe Willmar Gmbh & Co Aerosol-zubereitung und verwendung eines treibmittels dafuer
EP0616524B1 (de) 1991-12-12 1998-10-07 Glaxo Group Limited Arzneimittel
US5744123A (en) * 1991-12-12 1998-04-28 Glaxo Group Limited Aerosol formulations containing P134a and particulate medicaments
US5658549A (en) * 1991-12-12 1997-08-19 Glaxo Group Limited Aerosol formulations containing propellant 134a and fluticasone propionate
IL104068A (en) * 1991-12-12 1998-10-30 Glaxo Group Ltd Surfactant-free pharmaceutical aerosol formulation comprising 1,1,1,2-tetrafluoroethane or 1,1,1,2,3,3,3-heptafluoro-n- propane as propellant
US5674471A (en) * 1991-12-12 1997-10-07 Glaxo Group Limited Aerosol formulations containing P134a and salbutamol
NZ246046A (en) * 1991-12-12 1995-12-21 Glaxo Group Ltd Aerosol comprising a particulate medicament in a fluorocarbon or chlorofluorohydrocarbon and a polar cosolvent
US5683676A (en) * 1991-12-12 1997-11-04 Glaxo Group Limited Canister containing aerosol formulations containing P134a and particulate medicaments
US5916540A (en) 1994-10-24 1999-06-29 Glaxo Group Limited Aerosol formulations containing P134A and/or P227 and particulate medicament
US5736124A (en) * 1991-12-12 1998-04-07 Glaxo Group Limited Aerosol formulations containing P134a and particulate medicament
US7105152B1 (en) 1991-12-18 2006-09-12 3M Innovative Properties Company Suspension aerosol formulations
US7101534B1 (en) 1991-12-18 2006-09-05 3M Innovative Properties Company Suspension aerosol formulations
US5376359A (en) * 1992-07-07 1994-12-27 Glaxo, Inc. Method of stabilizing aerosol formulations
MX9304585A (es) 1992-07-31 1994-03-31 Glaxo Group Ltd Formulacion farmaceutica en aerosol, lata adecuada para liberar la formulacion e inhalador de dosis dosificada que comprende la lata.
NZ263410A (en) * 1993-03-17 1997-05-26 Minnesota Mining & Mfg Pharmaceutical aerosol containing diol-diacid derived dispersing aid
AU679511B2 (en) * 1993-03-17 1997-07-03 Minnesota Mining And Manufacturing Company Aerosol formulation containing an ester-, amide-, or mercaptoester-derived dispersing aid
GB9322014D0 (en) 1993-10-26 1993-12-15 Co Ordinated Drug Dev Improvements in and relating to carrier particles for use in dry powder inhalers
DE69424181T2 (de) * 1993-12-20 2000-10-19 Minnesota Mining And Mfg. Co., Saint Paul Flunisolide aerosolformulierungen
PE44995A1 (es) * 1994-01-27 1995-12-18 Schering Corp Furoato de mometasona para el tratamiento de las enfermedades pulmonares y de las vias respiratorias
GB9419536D0 (en) * 1994-09-28 1994-11-16 Glaxo Inc Medicaments
GB9425160D0 (en) * 1994-12-10 1995-02-08 Glaxo Group Ltd Medicaments
US6524557B1 (en) 1994-12-22 2003-02-25 Astrazeneca Ab Aerosol formulations of peptides and proteins
ATE236617T1 (de) 1994-12-22 2003-04-15 Astrazeneca Ab Aerosol-arzneiformulierungen
GB9501841D0 (en) 1995-01-31 1995-03-22 Co Ordinated Drug Dev Improvements in and relating to carrier particles for use in dry powder inhalers
GB9507768D0 (en) * 1995-04-13 1995-05-31 Glaxo Group Ltd Method of apparatus
GB9515182D0 (en) * 1995-07-24 1995-09-20 Co Ordinated Drug Dev Improvements in and relating to powders for use in dry powder inhalers
US5874469A (en) * 1996-01-05 1999-02-23 Alcon Laboratories, Inc. Fluoroalkyl hydrocarbons for administering water insoluble or unstable drugs
GB9616237D0 (en) 1996-08-01 1996-09-11 Norton Healthcare Ltd Aerosol formulations
US6120752A (en) * 1997-05-21 2000-09-19 3M Innovative Properties Company Medicinal aerosol products containing formulations of ciclesonide and related steroids
GB9805938D0 (en) 1998-03-19 1998-05-13 Glaxo Group Ltd Valve for aerosol container
US6264923B1 (en) 1998-05-13 2001-07-24 3M Innovative Properties Company Medicinal aerosol formulation of ciclesonide and related compounds
AU777278B2 (en) 1999-06-05 2004-10-07 Innovata Biomed Limited Delivery system
GB9920839D0 (en) 1999-09-04 1999-11-10 Innovata Biomed Ltd Inhaler
US6451287B1 (en) * 2000-05-26 2002-09-17 Smithkline Beecham Corporation Fluorinated copolymer surfactants and use thereof in aerosol compositions
WO2002024623A2 (en) 2000-09-22 2002-03-28 Glaxo Group Limited Novel alkanoic acid derivatives
AU2002222304B2 (en) 2000-12-22 2004-03-18 Glaxo Group Limited Metered dose inhaler for salmeterol xinafoate
GB0208742D0 (en) 2002-04-17 2002-05-29 Bradford Particle Design Ltd Particulate materials
AU2002321422B2 (en) 2001-08-03 2006-05-25 Glaxo Group Limited Surfactant compounds and uses thereof
GB0125127D0 (en) 2001-10-19 2001-12-12 Glaxo Group Ltd Compounds
GB0128148D0 (en) 2001-11-23 2002-01-16 Innovata Biomed Ltd Assembly
EP1474376A1 (de) 2002-02-13 2004-11-10 Glaxo Group Limited Carbonsäureverbindungen als tenside
GB0205327D0 (en) 2002-03-06 2002-04-17 Glaxo Group Ltd compounds
US7185651B2 (en) 2002-06-18 2007-03-06 Nektar Therapeutics Flow regulator for aerosol drug delivery and methods
WO2004110460A1 (en) 2003-06-13 2004-12-23 Altana Pharma Ag Formoterol and ciclesonide combination
US7589234B2 (en) 2003-07-02 2009-09-15 Daikin Industries, Ltd. Fluoroalkyl carboxylic acid derivative, method for producing fluorine-containing polymer, and aqueous dispersion of fluorine-containing polymer
AU2004264941B2 (en) 2003-08-11 2008-11-27 Glaxo Group Limited Pharmaceutical metered dose inhaler and methods relating thereto
WO2005023330A2 (en) 2003-08-29 2005-03-17 Glaxo Group Limited Pharmaceutical metered dose inhaler and methods relating thereto
DK1670482T4 (da) 2003-09-16 2022-08-22 Covis Pharma B V Anvendelse af ciclesonid til behandlingen af respiratoriske sygdomme
JP2007533387A (ja) 2004-04-21 2007-11-22 イノベータ バイオメド リミテッド 吸入器
EP2120875B1 (de) 2007-02-11 2018-07-11 Map Pharmaceuticals Inc. Verfahren zur therapeutischen verabreichung von dhe zur schnellen linderung von migräne bei gleichzeitiger minimierung von nebenwirkungsprofilen
CA2747790A1 (en) 2009-01-05 2010-07-08 Fraunhofer-Gesellschaft Zur Foerderung Der Angewandten Forschung E.V. Means and method for the treatment of antibody deficiency diseases based on il-21 and il-21 variants
AR079451A1 (es) 2009-12-18 2012-01-25 Nycomed Gmbh Compuestos 3,4,4a,10b-tetrahidro-1h-tiopirano[4,3-c]isoquinolina
CN103096917A (zh) 2010-06-04 2013-05-08 三叶草私人有限公司 用于治疗慢性肺病的三叶因子(tff)
EP2613773A2 (de) 2010-09-09 2013-07-17 Trifoilium ApS Verabreichung von angiogenesehemmern über die atemwege
EP2721036B1 (de) 2011-06-15 2015-07-22 Takeda GmbH Neuartige 3,4,4a,10b-tetrahydro-1h-thiopyrano[4,3-c]isochinolin-verbindungen
AR086915A1 (es) 2011-06-17 2014-01-29 Nycomed Gmbh Derivados de ftalazinona-pirrolopirimidinacarboxamida y composiciones farmaceuticas que los contiene
WO2018069210A1 (en) 2016-10-10 2018-04-19 Takeda Gmbh Tetrahydrofuro[3,4-c]isoquinolines as inhibitors of pde4

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US3250808A (en) * 1963-10-31 1966-05-10 Du Pont Fluorocarbon ethers derived from hexafluoropropylene epoxide
US4044126A (en) * 1972-04-20 1977-08-23 Allen & Hanburys Limited Steroidal aerosol compositions and process for the preparation thereof
JPS5331582A (en) * 1976-09-04 1978-03-24 Daikin Ind Ltd Aerosol composition
US4352789A (en) * 1980-03-17 1982-10-05 Minnesota Mining And Manufacturing Company Aerosol compositions containing finely divided solid materials
GB8900267D0 (en) * 1989-01-06 1989-03-08 Riker Laboratories Inc Narcotic analgesic formulations and apparatus containing same
IL97065A (en) * 1990-02-02 1994-01-25 Fisons Plc Repellent preparations for aerosol

Also Published As

Publication number Publication date
DE69131867D1 (de) 2000-01-27
EP0636362A2 (de) 1995-02-01
DE69131867T2 (de) 2000-05-18
AU654813B2 (en) 1994-11-24
AU7668691A (en) 1991-10-21
EP0636362B1 (de) 1999-12-22
EP0526481A1 (de) 1993-02-10
DE69109284D1 (de) 1995-06-01
ES2071306T3 (es) 1995-06-16
EP0965335B1 (de) 2003-09-17
DE69109284T2 (de) 1995-08-24
JPH05505824A (ja) 1993-08-26
WO1991014422A1 (en) 1991-10-03
CA2077354A1 (en) 1991-09-24
EP0636362A3 (de) 1995-12-27
EP0965335A1 (de) 1999-12-22
EP0526481B1 (de) 1995-04-26

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Legal Events

Date Code Title Description
8332 No legal effect for de