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DE69132814D1 - Neues insulinähnliches wachstumsfaktor bindendes protein igfbp-5 - Google Patents

Neues insulinähnliches wachstumsfaktor bindendes protein igfbp-5

Info

Publication number
DE69132814D1
DE69132814D1 DE69132814T DE69132814T DE69132814D1 DE 69132814 D1 DE69132814 D1 DE 69132814D1 DE 69132814 T DE69132814 T DE 69132814T DE 69132814 T DE69132814 T DE 69132814T DE 69132814 D1 DE69132814 D1 DE 69132814D1
Authority
DE
Germany
Prior art keywords
growth factor
binding protein
protein
dna molecules
binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69132814T
Other languages
English (en)
Other versions
DE69132814T2 (de
Inventor
C Kiefer
Frank Masiarz
Johann Zapf
Hans Born
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Vaccines and Diagnostics Inc
Original Assignee
Chiron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiron Corp filed Critical Chiron Corp
Publication of DE69132814D1 publication Critical patent/DE69132814D1/de
Application granted granted Critical
Publication of DE69132814T2 publication Critical patent/DE69132814T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4743Insulin-like growth factor binding protein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE69132814T 1990-08-28 1991-08-28 Neues insulinähnliches wachstumsfaktor bindendes protein igfbp-5 Expired - Fee Related DE69132814T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US57461390A 1990-08-28 1990-08-28
US57739190A 1990-08-31 1990-08-31
PCT/US1991/006141 WO1992003471A1 (en) 1990-08-28 1991-08-28 New insulin-like growth factor binding protein igfbp-5

Publications (2)

Publication Number Publication Date
DE69132814D1 true DE69132814D1 (de) 2002-01-03
DE69132814T2 DE69132814T2 (de) 2002-06-13

Family

ID=27076437

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69132814T Expired - Fee Related DE69132814T2 (de) 1990-08-28 1991-08-28 Neues insulinähnliches wachstumsfaktor bindendes protein igfbp-5

Country Status (8)

Country Link
EP (1) EP0546110B1 (de)
JP (1) JPH06503949A (de)
AT (1) ATE208816T1 (de)
CA (1) CA2090702A1 (de)
DE (1) DE69132814T2 (de)
IE (1) IE913034A1 (de)
PT (1) PT98805B (de)
WO (1) WO1992003471A1 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5969124A (en) * 1992-06-26 1999-10-19 Case Western Reserve University Nucleotide sequence of L1CAM
CA2148685A1 (en) 1992-11-04 1994-05-11 Dennis L. Andress Truncated insulin-like growth factor binding proteins having mitogenic activity
FI953615A7 (fi) * 1993-01-29 1995-07-28 Amgen Boulder Inc Haavanparannuskoostumus
US5712381A (en) * 1994-10-19 1998-01-27 Genetics Institute, Inc. MADD, a TNF receptor death domain ligand protein
US5847099A (en) * 1994-10-19 1998-12-08 Genetics Institute, Inc. TNF receptor death domain ligand proteins
US5852173A (en) * 1994-10-19 1998-12-22 Genetics Institute, Inc. TNF receptor death ligand proteins and inhibitors of ligand binding
US5849501A (en) * 1994-10-19 1998-12-15 Genetics Institute, Inc. TNF receptor death domain ligand proteins and method to identify inhibitors of ligand binding
AU710568B2 (en) * 1994-12-09 1999-09-23 Human Genome Sciences, Inc. Human vascular IBP-like growth factor
PT871730E (pt) 1995-10-11 2004-11-30 Chiron Corp Combinacao de pdgf, kgf, igf e igfbp para cicatrizacao de ferimentos
WO2000036105A1 (en) * 1998-12-18 2000-06-22 Human Genome Sciences, Inc. Prostacyclin-stimulating factor-2
EP1870464A3 (de) * 1999-06-02 2008-03-12 Genentech, Inc. Verfahren und Zusammensetzungen zur Hemmung des neoplastischen Zellenwachstums
US7491816B2 (en) 1999-07-19 2009-02-17 The University Of British Columbia Antisense therapy for hormone-regulated tumors
KR100856475B1 (ko) 1999-07-19 2008-09-08 더 유니버시티 오브 브리티쉬 콜롬비아 호르몬으로 조절되는 종양에 적합한 안티센스 치료법
US20020142963A1 (en) * 2000-10-24 2002-10-03 Andress Dennis L. Methods for increasing bone formation and enhancing bone accretion
AUPR633101A0 (en) * 2001-07-13 2001-08-02 University Of Sydney, The Method
NZ577565A (en) 2001-10-09 2010-10-29 Isis Pharmaceuticals Inc Antisense modulation of insulin-like growth factor binding protein 5 expressions
US6750019B2 (en) 2001-10-09 2004-06-15 Isis Pharmaceuticals, Inc. Antisense modulation of insulin-like growth factor binding protein 5 expression
JP4491240B2 (ja) 2002-01-17 2010-06-30 ザ ユニバーシティ オブ ブリティッシュ コロンビア Igfbp−2およびigfbp−5を阻害する二重特異性アンチセンスオリゴヌクレオチド、並びにこれらの使用方法
US7538195B2 (en) 2002-06-14 2009-05-26 Immunogen Inc. Anti-IGF-I receptor antibody
EP1667731B1 (de) 2003-10-01 2013-05-22 The University Of British Columbia Bispezifisches oligonucleotid zur behandlung von malignen zns-erkrankungen
AU2004278311A1 (en) 2003-10-03 2005-04-14 Genentech, Inc. IGF binding proteins
JP5093783B2 (ja) 2006-04-20 2012-12-12 クリングルファーマ株式会社 Hgf前駆体蛋白質改変体及びその活性型蛋白質

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK131988A (da) * 1988-03-11 1989-09-12 Erasmus University Igf-bindingsprotein, dna-struktur, der koder for igf-bindingsproteinet og vektor indeholdende denne dna-struktur

Also Published As

Publication number Publication date
ATE208816T1 (de) 2001-11-15
PT98805B (pt) 1999-01-29
EP0546110A1 (de) 1993-06-16
EP0546110A4 (en) 1994-08-17
CA2090702A1 (en) 1992-03-01
PT98805A (pt) 1992-08-31
WO1992003471A1 (en) 1992-03-05
EP0546110B1 (de) 2001-11-14
JPH06503949A (ja) 1994-05-12
DE69132814T2 (de) 2002-06-13
IE913034A1 (en) 1992-03-11

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: NOVARTIS VACCINES AND DIAGNOSTICS,INC.(N.D.GES, US

8339 Ceased/non-payment of the annual fee