DE69010025D1 - Verfahren zur Herstellung von 14-Alpha-hydroxy-4-androsten-3,6,17, trion. - Google Patents
Verfahren zur Herstellung von 14-Alpha-hydroxy-4-androsten-3,6,17, trion.Info
- Publication number
- DE69010025D1 DE69010025D1 DE69010025T DE69010025T DE69010025D1 DE 69010025 D1 DE69010025 D1 DE 69010025D1 DE 69010025 T DE69010025 T DE 69010025T DE 69010025 T DE69010025 T DE 69010025T DE 69010025 D1 DE69010025 D1 DE 69010025D1
- Authority
- DE
- Germany
- Prior art keywords
- alpha
- trione
- hydroxy
- preparation
- androsten
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- VOYADQIFGGIKAT-UHFFFAOYSA-N 1,3-dibutyl-4-hydroxy-2,6-dioxopyrimidine-5-carboximidamide Chemical compound CCCCn1c(O)c(C(N)=N)c(=O)n(CCCC)c1=O VOYADQIFGGIKAT-UHFFFAOYSA-N 0.000 title 1
- UDHAKZRCGHAPAZ-NFBMXZEVSA-N (6r,8r,9s,10r,13s,14r)-6,14-dihydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,15,16-decahydrocyclopenta[a]phenanthrene-3,17-dione Chemical compound O=C1CC[C@]2(C)[C@H]3CC[C@](C)(C(CC4)=O)[C@]4(O)[C@@H]3C[C@@H](O)C2=C1 UDHAKZRCGHAPAZ-NFBMXZEVSA-N 0.000 abstract 1
- UKVVNEHFNYKGMX-KIVPVIKRSA-N (8r,9s,10r,13s,14r)-14-hydroxy-10,13-dimethyl-2,7,8,9,11,12,15,16-octahydro-1h-cyclopenta[a]phenanthrene-3,6,17-trione Chemical compound O=C1CC[C@]2(C)[C@H]3CC[C@](C)(C(CC4)=O)[C@]4(O)[C@@H]3CC(=O)C2=C1 UKVVNEHFNYKGMX-KIVPVIKRSA-N 0.000 abstract 1
- 102000014654 Aromatase Human genes 0.000 abstract 1
- 108010078554 Aromatase Proteins 0.000 abstract 1
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1027824A JPH0643439B2 (ja) | 1989-02-07 | 1989-02-07 | 光による６β，１４α‐ジヒドロキシ‐４‐アンドロステン‐３，１７‐ジオンの６β位水酸基の酸化方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69010025D1 true DE69010025D1 (de) | 1994-07-28 |
| DE69010025T2 DE69010025T2 (de) | 1994-12-15 |
Family
ID=12231698
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69010025T Expired - Fee Related DE69010025T2 (de) | 1989-02-07 | 1990-02-06 | Verfahren zur Herstellung von 14-Alpha-hydroxy-4-androsten-3,6,17, trion. |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US5098535A (de) |
| EP (1) | EP0382162B1 (de) |
| JP (1) | JPH0643439B2 (de) |
| AT (1) | ATE107656T1 (de) |
| DE (1) | DE69010025T2 (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH06225793A (ja) * | 1992-11-27 | 1994-08-16 | Nippon Kayaku Co Ltd | ６β，１４α−ジヒドロキシ−４−アンドロステン−３，１７−ジオンの新規製造法 |
| EP0626388A3 (en) * | 1993-05-28 | 1996-06-19 | Nippon Kayaku Kk | 14alpha-hydroxy-4-androstene-3,6,17-trione hydrate crystal and process for producing same. |
| ES2817789T3 (es) | 2012-11-12 | 2021-04-08 | Hollister Inc | Conjunto de catéter intermitente |
| DK2919825T3 (en) | 2012-11-14 | 2019-02-11 | Hollister Inc | Disposable catheter with selectively degradable inner core |
| ES2869024T3 (es) | 2013-11-08 | 2021-10-22 | Hollister Inc | Catéteres oleófilos lubricados |
| WO2015089189A2 (en) | 2013-12-12 | 2015-06-18 | Hollister Incorporated | Flushable catheters |
| AU2014363920B2 (en) | 2013-12-12 | 2017-08-31 | Hollister Incorporated | Flushable catheters |
| CA2933525C (en) | 2013-12-12 | 2020-11-17 | Hollister Incorporated | Flushable catheters |
| HUE051635T2 (hu) | 2013-12-12 | 2021-03-01 | Hollister Inc | Toalettben lehúzható szétmálló katéter |
| CA2989330C (en) | 2015-06-17 | 2023-01-31 | Hollister Incorporated | Selectively water disintegrable materials and catheters made of such materials |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2900382A (en) * | 1952-06-28 | 1959-08-18 | Syntex Sa | Method of making delta4,6 steroid compounds from delta4 steroid compounds |
| WO1988005781A1 (fr) * | 1987-02-06 | 1988-08-11 | Snow Brand Milk Products Co., Ltd. | Nouveaux derives d'androst-4-ene-3,17-dione et procede de preparation |
| JPS63192794A (ja) * | 1987-02-06 | 1988-08-10 | Snow Brand Milk Prod Co Ltd | １４α−ヒドロキシ−４−アンドロステン−３，６，１７−トリオン |
-
1989
- 1989-02-07 JP JP1027824A patent/JPH0643439B2/ja not_active Expired - Lifetime
-
1990
- 1990-02-06 DE DE69010025T patent/DE69010025T2/de not_active Expired - Fee Related
- 1990-02-06 EP EP90102302A patent/EP0382162B1/de not_active Expired - Lifetime
- 1990-02-06 AT AT90102302T patent/ATE107656T1/de not_active IP Right Cessation
- 1990-02-06 US US07/475,502 patent/US5098535A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0382162A2 (de) | 1990-08-16 |
| US5098535A (en) | 1992-03-24 |
| JPH0643439B2 (ja) | 1994-06-08 |
| EP0382162A3 (de) | 1991-03-13 |
| ATE107656T1 (de) | 1994-07-15 |
| EP0382162B1 (de) | 1994-06-22 |
| DE69010025T2 (de) | 1994-12-15 |
| JPH02207095A (ja) | 1990-08-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |