DE69925824D1 - Glutathionderivate und dazugehörige dosisformen - Google Patents
Glutathionderivate und dazugehörige dosisformenInfo
- Publication number
- DE69925824D1 DE69925824D1 DE69925824T DE69925824T DE69925824D1 DE 69925824 D1 DE69925824 D1 DE 69925824D1 DE 69925824 T DE69925824 T DE 69925824T DE 69925824 T DE69925824 T DE 69925824T DE 69925824 D1 DE69925824 D1 DE 69925824D1
- Authority
- DE
- Germany
- Prior art keywords
- alkyl group
- group
- dosage forms
- alkenyl group
- derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- RWSXRVCMGQZWBV-WDSKDSINSA-N glutathione Chemical class OC(=O)[C@@H](N)CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O RWSXRVCMGQZWBV-WDSKDSINSA-N 0.000 title abstract 4
- 239000002552 dosage form Substances 0.000 title 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 4
- 125000000008 (C1-C10) alkyl group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 230000018109 developmental process Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000011132 hemopoiesis Effects 0.000 abstract 1
- 230000001737 promoting effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0215—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10635998 | 1998-04-16 | ||
| PCT/JP1999/002044 WO1999054346A1 (en) | 1998-04-16 | 1999-04-16 | Glutathione derivatives and dosage forms thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE69925824D1 true DE69925824D1 (de) | 2005-07-21 |
Family
ID=14431564
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69925824T Expired - Lifetime DE69925824D1 (de) | 1998-04-16 | 1999-04-16 | Glutathionderivate und dazugehörige dosisformen |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US6627732B1 (de) |
| EP (1) | EP1072608B1 (de) |
| JP (1) | JP4059627B2 (de) |
| KR (1) | KR20010042752A (de) |
| AT (1) | ATE297945T1 (de) |
| AU (1) | AU766515B2 (de) |
| CA (1) | CA2328731A1 (de) |
| DE (1) | DE69925824D1 (de) |
| TW (1) | TW576838B (de) |
| WO (1) | WO1999054346A1 (de) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7029695B2 (en) | 2001-07-10 | 2006-04-18 | Telik, Inc. | Therapeutic compositions containing glutathione analogs |
| US6747009B2 (en) * | 2002-09-19 | 2004-06-08 | Universiteit Leiden | Peptidomimetic glutathione analogs |
| US8198247B2 (en) * | 2004-12-21 | 2012-06-12 | Telik, Inc. | Process for and intermediates in the preparation of canfosfamide and its salts |
| DK1833978T3 (da) | 2005-01-06 | 2009-02-09 | Telik Inc | Tripeptid- og tetrapeptidthioethere |
| US8067380B2 (en) | 2005-12-19 | 2011-11-29 | Industrial Technology Research Institute | Glutathione-based delivery system |
| US7446096B2 (en) * | 2005-12-19 | 2008-11-04 | Industrial Technology Research Institute | Glutathione based delivery system |
| EP2123284A4 (de) * | 2007-03-20 | 2011-07-06 | Univ Osaka | Vorbeugender und/oder therapeutischer wirkstoff für herzinfarkte |
| ES2322121B1 (es) * | 2007-12-10 | 2010-04-19 | Consejo Superior De Investigaciones Cientificas | Nuevos derivados de aminoacidos dicarboxilicos y su aplicacion en el tratamiento de enfermedades neurodegenerativas. |
| US8609604B2 (en) | 2009-12-28 | 2013-12-17 | N.V. Perricone Llc | Methods of improving the appearance of aging skin |
| US8580742B2 (en) * | 2010-03-05 | 2013-11-12 | N.V. Perricone Llc | Topical glutathione formulations for menopausal skin |
| US20110160144A1 (en) * | 2009-12-28 | 2011-06-30 | Perricone Nicholas V | Topical Acyl Glutathione Formulations |
| JP2013528214A (ja) | 2010-06-07 | 2013-07-08 | テリック，インコーポレイテッド | 結晶性エザチオスタット塩酸塩非溶媒和物ｄ型の調製 |
| CN102917694A (zh) * | 2010-06-07 | 2013-02-06 | 泰立克公司 | 依泽替米贝的片剂制剂 |
| EP2724729B1 (de) | 2011-06-21 | 2018-12-26 | Nitto Denko Corporation | Apoptoseauslöser |
| US20140120157A1 (en) * | 2012-09-19 | 2014-05-01 | Georgetown University | Targeted liposomes |
| JP6340162B2 (ja) | 2012-12-20 | 2018-06-06 | 日東電工株式会社 | アポトーシス誘導剤 |
| US10093931B2 (en) | 2014-06-17 | 2018-10-09 | Nitto Denko Corporation | Apoptosis inducer |
| US10264976B2 (en) | 2014-12-26 | 2019-04-23 | The University Of Akron | Biocompatible flavonoid compounds for organelle and cell imaging |
| RU2692065C1 (ru) * | 2018-04-05 | 2019-06-20 | федеральное государственное автономное образовательное учреждение высшего образования "Казанский (Приволжский) федеральный университет" (ФГАОУ ВО КФУ) | Глутатионаммониевые соли o,o-диорганилдитиофосфорных кислот, обладающие антиоксидантной и противоопухолевой активностью |
| ES2972334T3 (es) | 2018-11-16 | 2024-06-12 | Nitto Denko Corp | Formulación y métodos de administración de interferencia de ARN para tumores malignos |
| US11419849B1 (en) | 2019-02-06 | 2022-08-23 | Kitt Bio, Inc. | Methods and products for adverse effects of air travel, jet lag, or a change to a sleep wake timing cycle |
| WO2020230701A1 (ja) | 2019-05-14 | 2020-11-19 | 学校法人 慶應義塾 | 抗腫瘍剤及び配合剤 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995005863A1 (en) | 1993-08-27 | 1995-03-02 | St. Paul Medical, Inc. | Needleless iv medical delivery system |
| WO1996040205A1 (en) * | 1995-06-07 | 1996-12-19 | Terrapin Technologies, Inc. | Metabolic effects of certain glutathione analogs |
| WO1999037802A1 (en) | 1998-01-21 | 1999-07-29 | Telik, Inc. | Methods to identify myelostimulants |
| CN1185008C (zh) | 1999-01-27 | 2005-01-19 | 泰立克公司 | 含有谷胱甘肽类似物的治疗用组合物 |
-
1999
- 1999-04-16 US US09/673,449 patent/US6627732B1/en not_active Expired - Fee Related
- 1999-04-16 JP JP2000544684A patent/JP4059627B2/ja not_active Expired - Fee Related
- 1999-04-16 WO PCT/JP1999/002044 patent/WO1999054346A1/ja not_active Ceased
- 1999-04-16 KR KR1020007011484A patent/KR20010042752A/ko not_active Ceased
- 1999-04-16 TW TW088106145A patent/TW576838B/zh active
- 1999-04-16 CA CA002328731A patent/CA2328731A1/en not_active Abandoned
- 1999-04-16 DE DE69925824T patent/DE69925824D1/de not_active Expired - Lifetime
- 1999-04-16 EP EP99914763A patent/EP1072608B1/de not_active Expired - Lifetime
- 1999-04-16 AU AU33445/99A patent/AU766515B2/en not_active Ceased
- 1999-04-16 AT AT99914763T patent/ATE297945T1/de not_active IP Right Cessation
-
2003
- 2003-07-21 US US10/622,799 patent/US20040018985A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| ATE297945T1 (de) | 2005-07-15 |
| JP4059627B2 (ja) | 2008-03-12 |
| US20040018985A1 (en) | 2004-01-29 |
| AU766515B2 (en) | 2003-10-16 |
| EP1072608A1 (de) | 2001-01-31 |
| AU3344599A (en) | 1999-11-08 |
| US6627732B1 (en) | 2003-09-30 |
| TW576838B (en) | 2004-02-21 |
| WO1999054346A1 (en) | 1999-10-28 |
| KR20010042752A (ko) | 2001-05-25 |
| EP1072608A4 (de) | 2001-09-19 |
| EP1072608B1 (de) | 2005-06-15 |
| CA2328731A1 (en) | 1999-10-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8332 | No legal effect for de |