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DE69915144D1 - Aerosoldruckdosiergeräte und Aerosolarzneizusammensetzungen - Google Patents

Aerosoldruckdosiergeräte und Aerosolarzneizusammensetzungen

Info

Publication number
DE69915144D1
DE69915144D1 DE69915144T DE69915144T DE69915144D1 DE 69915144 D1 DE69915144 D1 DE 69915144D1 DE 69915144 T DE69915144 T DE 69915144T DE 69915144 T DE69915144 T DE 69915144T DE 69915144 D1 DE69915144 D1 DE 69915144D1
Authority
DE
Germany
Prior art keywords
aerosol
pharmaceutical compositions
dosing devices
pressure dosing
aerosol pharmaceutical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69915144T
Other languages
English (en)
Other versions
DE69915144T2 (de
Inventor
Frank E Blondino
Michael Brucato
Maria W Buenafe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ivax Research Holdings Inc
Original Assignee
Ivax Research Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ivax Research Inc filed Critical Ivax Research Inc
Application granted granted Critical
Publication of DE69915144D1 publication Critical patent/DE69915144D1/de
Publication of DE69915144T2 publication Critical patent/DE69915144T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A61K9/124—Aerosols; Foams characterised by the propellant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69915144T 1998-06-19 1999-06-18 Aerosoldruckdosiergeräte und Aerosolarzneizusammensetzungen Expired - Fee Related DE69915144T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US99779 1998-06-19
US09/099,779 US6451285B2 (en) 1998-06-19 1998-06-19 Suspension aerosol formulations containing formoterol fumarate and a fluoroalkane propellant

Publications (2)

Publication Number Publication Date
DE69915144D1 true DE69915144D1 (de) 2004-04-01
DE69915144T2 DE69915144T2 (de) 2004-12-09

Family

ID=22276581

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69911602T Expired - Fee Related DE69911602T2 (de) 1998-06-19 1999-06-18 Druckdosierinhalator und pharmazeutische aerosol formulierungen enthaltend einen beta-agonisten
DE69915144T Expired - Fee Related DE69915144T2 (de) 1998-06-19 1999-06-18 Aerosoldruckdosiergeräte und Aerosolarzneizusammensetzungen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE69911602T Expired - Fee Related DE69911602T2 (de) 1998-06-19 1999-06-18 Druckdosierinhalator und pharmazeutische aerosol formulierungen enthaltend einen beta-agonisten

Country Status (23)

Country Link
US (2) US6451285B2 (de)
EP (2) EP1306082B1 (de)
JP (1) JP2002518100A (de)
KR (1) KR20010053025A (de)
CN (2) CN1154477C (de)
AR (1) AR018891A1 (de)
AT (2) ATE250409T1 (de)
AU (1) AU762927B2 (de)
BR (1) BR9912170A (de)
CA (1) CA2335303A1 (de)
CO (1) CO5031245A1 (de)
DE (2) DE69911602T2 (de)
DK (2) DK1085856T3 (de)
ES (2) ES2215153T3 (de)
HU (1) HUP0102468A3 (de)
IL (1) IL140340A0 (de)
NO (1) NO20006466L (de)
PL (1) PL345399A1 (de)
PT (2) PT1306082E (de)
RU (1) RU2214230C2 (de)
SK (1) SK19442000A3 (de)
WO (1) WO1999065460A2 (de)
ZA (1) ZA200007455B (de)

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US6451285B2 (en) * 1998-06-19 2002-09-17 Baker Norton Pharmaceuticals, Inc. Suspension aerosol formulations containing formoterol fumarate and a fluoroalkane propellant
DZ2947A1 (fr) * 1998-11-25 2004-03-15 Chiesi Farma Spa Inhalateur à compteur de dose sous pression.
US6315985B1 (en) * 1999-06-18 2001-11-13 3M Innovative Properties Company C-17/21 OH 20-ketosteroid solution aerosol products with enhanced chemical stability
IT1313553B1 (it) 1999-07-23 2002-09-09 Chiesi Farma Spa Formulazioni ottimizzate costituite da soluzioni di steroidi dasomministrare per inalazione.
IT1317720B1 (it) * 2000-01-07 2003-07-15 Chiesi Farma Spa Dispositivo per la somministrazione di aerosol dosati pressurizzati inpropellenti idrofluoroalcani.
IT1317846B1 (it) * 2000-02-22 2003-07-15 Chiesi Farma Spa Formulazioni contenenti un farmaco anticolinergico per il trattamentodella broncopneumopatia cronica ostruttiva.
IT1318514B1 (it) * 2000-05-12 2003-08-27 Chiesi Farma Spa Formulazioni contenenti un farmaco glucocorticosteroide per iltrattamento di patologie broncopolmonari.
MXPA02011414A (es) * 2000-05-22 2003-06-06 Chiesi Farma Spa Formulaciones farmaceuticas en solucion estable para inhaladores presurizados con medicion de dosis.
US20060257324A1 (en) 2000-05-22 2006-11-16 Chiesi Farmaceutici S.P.A. Pharmaceutical solution formulations for pressurised metered dose inhalers
US20030072717A1 (en) * 2001-02-23 2003-04-17 Vapotronics, Inc. Inhalation device having an optimized air flow path
AU2002234476B2 (en) * 2001-03-30 2006-04-27 Jagotec Ag Medical aerosol formulations
ES2222294T3 (es) * 2001-07-02 2005-02-01 Chiesi Farmaceutici S.P.A. Formulacion optimizada de tobramicina para administracion en forma de aerosol.
US20030178022A1 (en) * 2001-12-21 2003-09-25 Chiesi Farmaceutici S.P.A. Pressurized metered dose inhaler (PMDI) actuators and medicinal aerosol solution formulation products comprising therse actuators
DE10205087A1 (de) * 2002-02-07 2003-08-21 Pharmatech Gmbh Cyclodextrine als Suspensionsstabilisatoren in druckverflüssigten Treibmitteln
RS52387B (sr) * 2002-03-01 2013-02-28 Chiesi Farmaceutici S.P.A. Formoterol najfiniji preparat
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US6979580B2 (en) 2002-12-09 2005-12-27 Progressant Technologies, Inc. Process for controlling performance characteristics of a negative differential resistance (NDR) device
GB0323684D0 (en) * 2003-10-09 2003-11-12 Jagotec Ag Improvements in or relating to organic compounds
GB0323685D0 (en) * 2003-10-09 2003-11-12 Jagotec Ag Improvements in or relating to organic compounds
EP1595531A1 (de) 2004-05-13 2005-11-16 CHIESI FARMACEUTICI S.p.A. Stabile Arzneimittellösung für Druckdosierinhalatoren
WO2007008427A2 (en) * 2005-07-08 2007-01-18 Xemplar Pharmaceuticals, Llc Aerosol compositions and methods
US8367734B1 (en) 2005-08-11 2013-02-05 Amphastar Pharmaceuticals Inc. Stable epinephrine suspension formulation with high inhalation delivery efficiency
KR20120015334A (ko) * 2009-05-29 2012-02-21 펄 테라퓨틱스 인코포레이티드 활성제의 호흡기 전달용 조성물, 및 연관된 방법 및 시스템
US8815258B2 (en) 2009-05-29 2014-08-26 Pearl Therapeutics, Inc. Compositions, methods and systems for respiratory delivery of two or more active agents
GB0918149D0 (en) 2009-10-16 2009-12-02 Jagotec Ag Improved medicinal aerosol formulation
EP2512438B1 (de) 2009-12-16 2017-01-25 3M Innovative Properties Company Formulierungen und verfahren zur steuerung der mdi-partikelgrössenfreisetzung
GB201108039D0 (en) 2011-05-13 2011-06-29 Mexichem Amanco Holding Sa Compositions
GB201117621D0 (en) 2011-10-12 2011-11-23 Mexichem Amanco Holding Sa Compositions
GB201117619D0 (en) 2011-10-12 2011-11-23 Mexichem Amanco Holding Sa Compositions
EP2968152B2 (de) 2013-03-15 2022-06-22 Pearl Therapeutics, Inc. Verfahren und systeme zum konditionieren von teilchenförmigen kristallinen materialien
GB201306984D0 (en) 2013-04-17 2013-05-29 Mexichem Amanco Holding Sa Composition
CA3007050C (en) 2015-12-04 2020-12-08 Mexichem Fluor S.A. De C.V. Pharmaceutical composition comprising a formoterol compound
WO2018051133A1 (en) 2016-09-19 2018-03-22 Mexichem Fluor S.A. De C.V. Pharmaceutical composition
WO2018051128A1 (en) 2016-09-19 2018-03-22 Mexichem Fluor S.A. De C.V. Pharmaceutical composition
UA123919C2 (uk) 2016-09-19 2021-06-23 Мехікем Флуор С.А. Де С.В. Фармацевтична композиція
CN109464429B (zh) * 2018-12-13 2021-04-27 上海方予健康医药科技有限公司 一种吸入压力定量气雾剂药物组合物及其制备方法

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Also Published As

Publication number Publication date
DE69911602T2 (de) 2004-07-01
SK19442000A3 (sk) 2001-09-11
NO20006466D0 (no) 2000-12-18
DK1306082T3 (da) 2004-06-01
RU2214230C2 (ru) 2003-10-20
HUP0102468A2 (hu) 2002-03-28
ATE260093T1 (de) 2004-03-15
AU762927B2 (en) 2003-07-10
US20030077230A1 (en) 2003-04-24
PL345399A1 (en) 2001-12-17
DK1085856T3 (da) 2003-12-08
HUP0102468A3 (en) 2002-12-28
WO1999065460A2 (en) 1999-12-23
WO1999065460A3 (en) 2000-04-27
CN1522692A (zh) 2004-08-25
ES2215153T3 (es) 2004-10-01
DE69915144T2 (de) 2004-12-09
CN1154477C (zh) 2004-06-23
IL140340A0 (en) 2002-02-10
ES2205848T3 (es) 2004-05-01
BR9912170A (pt) 2001-10-23
EP1306082B1 (de) 2004-02-25
NO20006466L (no) 2001-02-16
US6451285B2 (en) 2002-09-17
DE69911602D1 (de) 2003-10-30
EP1085856A2 (de) 2001-03-28
ZA200007455B (en) 2002-06-13
US20020018753A1 (en) 2002-02-14
AR018891A1 (es) 2001-12-12
PT1306082E (pt) 2004-05-31
KR20010053025A (ko) 2001-06-25
EP1085856B1 (de) 2003-09-24
CA2335303A1 (en) 1999-12-23
JP2002518100A (ja) 2002-06-25
CN1310611A (zh) 2001-08-29
EP1306082A1 (de) 2003-05-02
CO5031245A1 (es) 2001-04-27
PT1085856E (pt) 2004-01-30
AU4825999A (en) 2000-01-05
ATE250409T1 (de) 2003-10-15

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Legal Events

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8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee