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DE69837664D1 - Wässrige suspensionspräparationen mit exzellenter redispersibilität - Google Patents

Wässrige suspensionspräparationen mit exzellenter redispersibilität

Info

Publication number
DE69837664D1
DE69837664D1 DE69837664T DE69837664T DE69837664D1 DE 69837664 D1 DE69837664 D1 DE 69837664D1 DE 69837664 T DE69837664 T DE 69837664T DE 69837664 T DE69837664 T DE 69837664T DE 69837664 D1 DE69837664 D1 DE 69837664D1
Authority
DE
Germany
Prior art keywords
aqueous suspension
suspension preparations
excellent redispersibility
redispersibility
preparations
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69837664T
Other languages
English (en)
Other versions
DE69837664T2 (de
Inventor
Shin-Ichi Yasueda
Keiichi Matsuhisa
Hideo Terayama
Katsuhiro Inada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Senju Pharmaceutical Co Ltd
Original Assignee
Senju Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Senju Pharmaceutical Co Ltd filed Critical Senju Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE69837664D1 publication Critical patent/DE69837664D1/de
Publication of DE69837664T2 publication Critical patent/DE69837664T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Otolaryngology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69837664T 1997-05-14 1998-04-30 Wässrige suspensionspräparationen mit exzellenter redispersibilität Expired - Lifetime DE69837664T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP12416697 1997-05-14
JP12416697 1997-05-14
PCT/JP1998/001998 WO1998051281A1 (en) 1997-05-14 1998-04-30 Aqueous suspension preparations with excellent redispersibility

Publications (2)

Publication Number Publication Date
DE69837664D1 true DE69837664D1 (de) 2007-06-06
DE69837664T2 DE69837664T2 (de) 2008-01-03

Family

ID=14878589

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69837664T Expired - Lifetime DE69837664T2 (de) 1997-05-14 1998-04-30 Wässrige suspensionspräparationen mit exzellenter redispersibilität

Country Status (7)

Country Link
US (3) US6274634B1 (de)
EP (1) EP0995435B1 (de)
KR (1) KR20010012188A (de)
CA (1) CA2289618A1 (de)
DE (1) DE69837664T2 (de)
ES (1) ES2284202T3 (de)
WO (1) WO1998051281A1 (de)

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EP1140021B1 (de) 1998-12-23 2004-08-04 Idea Ag Verbesserte formulierung zur topischen, nichtinvasiven anwendung in vivo
EP1031346B1 (de) 1999-01-27 2002-05-02 Idea Ag Nichtinvasive Impfung durch die Haut
ATE216223T1 (de) 1999-01-27 2002-05-15 Idea Ag Transnasaler transport bzw. impfung mit hochadaptierbaren trägern
MXPA02000053A (es) 1999-07-05 2003-07-21 Idea Ag Un metodo para mejorar el tratamiento a traves de barreras adaptables semipermeables.
US20020061281A1 (en) * 1999-07-06 2002-05-23 Osbakken Robert S. Aerosolized anti-infectives, anti-inflammatories, and decongestants for the treatment of sinusitis
US6576224B1 (en) * 1999-07-06 2003-06-10 Sinuspharma, Inc. Aerosolized anti-infectives, anti-inflammatories, and decongestants for the treatment of sinusitis
WO2001087262A2 (en) * 2000-05-15 2001-11-22 Pharmacia Italia S.P.A. Stabilized steroidal suspension
WO2002015878A1 (fr) * 2000-08-25 2002-02-28 Senju Pharmaceutical Co., Ltd. Preparations en suspension aqueuse
AU2001290328A1 (en) * 2000-09-29 2002-04-08 Wakamoto Pharmaceutical Co., Ltd. Eye drops comprising acyclovir suspension
WO2002048141A1 (fr) * 2000-12-11 2002-06-20 Takeda Chemical Industries, Ltd. Composition medicinale dont la solubilite dans l'eau est amelioree
FI112282B (fi) * 2001-01-12 2003-11-14 Kibron Inc Oy Menetelmä vesipitoisen liuoksen pintajännityksen mittaamiseksi
JP3805203B2 (ja) * 2001-02-16 2006-08-02 日本油脂株式会社 点眼用水性懸濁製剤およびその製造方法
AU2002257104B2 (en) * 2001-04-03 2006-02-09 Merck Sharp & Dohme Corp. Antifungal composition with enhanced bioavailability
US20030055026A1 (en) * 2001-04-17 2003-03-20 Dey L.P. Formoterol/steroid bronchodilating compositions and methods of use thereof
US20040023935A1 (en) * 2002-08-02 2004-02-05 Dey, L.P. Inhalation compositions, methods of use thereof, and process for preparation of same
US7473432B2 (en) * 2002-10-11 2009-01-06 Idea Ag NSAID formulations, based on highly adaptable aggregates, for improved transport through barriers and topical drug delivery
US20040109826A1 (en) * 2002-12-06 2004-06-10 Dey, L.P. Stabilized albuterol compositions and method of preparation thereof
WO2004073748A1 (ja) * 2003-02-20 2004-09-02 Senju Pharmaceutical Co., Ltd. 水性懸濁液剤
TWI359675B (en) 2003-07-10 2012-03-11 Dey L P Bronchodilating β-agonist compositions
EP1663144A1 (de) * 2003-09-23 2006-06-07 Alcon, Inc. Triamcinolon-acetonid und anecortav-acetat-formulierungen zur injektion
US20050136116A1 (en) * 2003-12-18 2005-06-23 Keith Whitehead Stabilized prednisolone sodium phosphate solutions
EP1802373B1 (de) * 2004-09-24 2011-07-06 RFE Pharma LLC Carboxy-amido-triazole zur lokalisierten behandlung von augenerkrankungen
WO2006050926A2 (en) * 2004-11-12 2006-05-18 Idea Ag Extended surface aggregates in the treatment of skin conditions
TWI363626B (en) 2004-11-15 2012-05-11 Otsuka Pharma Co Ltd Aqueous ophthalmic suspension of crystalline rebamipide
CN101237851B (zh) * 2005-06-16 2013-09-18 沃纳奇尔科特有限责任公司 用于阴道给药的雌激素组合物
US20070004693A1 (en) * 2005-06-16 2007-01-04 Warner Chilcott Company Inc. Estrogen compositions for vaginal administration
CA2612456C (en) * 2005-06-16 2017-06-06 Warner Chilcott Company, Inc. Gel compositions for topical administration
US20070099883A1 (en) * 2005-10-07 2007-05-03 Cheryl Lynn Calis Anhydrous mometasone furoate formulation
US7597333B2 (en) * 2006-04-05 2009-10-06 Acorn Products, Llc Brake assembly and scooters and skateboards including the same
TWI415629B (zh) * 2006-10-26 2013-11-21 Otsuka Pharma Co Ltd 含有瑞巴匹特之水性醫藥懸浮物及其製造方法
WO2008123396A1 (ja) * 2007-03-29 2008-10-16 Santen Pharmaceutical Co., Ltd. フルオロメトロンを含有する懸濁型点眼剤
US8300252B2 (en) * 2008-06-18 2012-10-30 Livescribe, Inc. Managing objects with varying and repeated printed positioning information
PL2366408T3 (pl) * 2010-03-01 2013-01-31 Salvat Lab Sa Klarowne roztwory wodne acetonidu fluocinolonu do leczenia zapalenia uszu
AR090775A1 (es) 2012-04-23 2014-12-03 Otsuka Pharma Co Ltd Preparado inyectable
EP2847207B1 (de) * 2012-05-08 2019-03-27 Nicox Ophthalmics, Inc. Nanokristalle von Fluticasonpropionat
US9308165B2 (en) * 2013-08-22 2016-04-12 Therapeutic Vision, Inc. Composition for treating ocular effects of diabetes
ES2865262T3 (es) 2013-08-30 2021-10-15 Nof Corp Solución oftálmica
ES2951202T3 (es) 2014-07-28 2023-10-19 Sun Pharma Advanced Res Co Ltd Método para aumentar la biodisponibilidad y/o prolongar la acción oftálmica de un fármaco
TWI773641B (zh) 2015-05-08 2022-08-11 日商活效製藥股份有限公司 含有糖皮質類固醇（ｇｌｕｃｏｃｏｒｔｉｃｏｉｄｓ）之奈米微粒子之水性懸浮液劑
JP7297308B2 (ja) 2016-08-19 2023-06-26 オラシス ファーマシューティカルズ リミティド 眼科用医薬組成物及びそれに関する使用
JP7175431B1 (ja) * 2021-03-30 2022-11-18 千寿製薬株式会社 ヘテロシクリデンアセトアミド誘導体含有懸濁液

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JPS60161915A (ja) 1984-02-01 1985-08-23 Sato Seiyaku Kk 制酸剤含有内用液剤
US5124392A (en) * 1988-10-03 1992-06-23 Alcon Laboratories, Inc. Pharmaceutical compositions and methods of treatment to prevent and treat corneal scar formation produced by laser irradiation
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JPH03135924A (ja) 1989-10-23 1991-06-10 Takada Seiyaku Kk 新規な消炎作用物質含有外用製剤
JP2554784B2 (ja) 1991-03-15 1996-11-13 杏林製薬株式会社 懸濁シロップ剤
JP2808378B2 (ja) * 1991-03-27 1998-10-08 武田薬品工業株式会社 水性懸濁液剤の製造法
DE69123248T2 (de) 1991-03-27 1997-03-13 Senju Pharma Co Verfahren zur herstellung einer wässrigen suspension
ES2079994B1 (es) * 1992-10-07 1996-08-01 Cusi Lab Formulacion farmaceutica a base de polimixina-trimetoprim y un agente antiinflamatorio para su utilizacion topica oftalmica y otica.
EP0694310B1 (de) * 1993-04-16 2000-02-16 Wakamoto Pharmaceutical Co., Ltd. Unter wärmeeinwirkung reversibel gelierende medizinische zusammensetzung auf wasserbasis
JPH08151332A (ja) 1994-09-28 1996-06-11 Senju Pharmaceut Co Ltd 点鼻用水性懸濁液
EP0709099A3 (de) 1994-09-28 1996-07-24 Senju Pharma Co Wässrige Suspension zur nasalen Verabreichung enthaltend Cyclodextrin
US5516808A (en) * 1994-10-27 1996-05-14 Sawaya; Assad S. Topical cellulose pharmaceutical formulation
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JP3269770B2 (ja) 1995-03-02 2002-04-02 参天製薬株式会社 再分散性の優れたイオン性高分子配合水性懸濁点眼剤
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US5811446A (en) * 1997-04-18 1998-09-22 Cytos Pharmaceuticals Llc Prophylactic and therapeutic methods for ocular degenerative diseases and inflammations and histidine compositions therefor
KR20010012188A (ko) * 1997-05-14 2001-02-15 요시다 쇼지 재분산성이 양호한 수성 현탁액제
CA2318642A1 (en) 1998-01-22 1999-07-29 Santen Pharmaceutical Co., Ltd. Fluorometholone ophthalmic suspension

Also Published As

Publication number Publication date
EP0995435B1 (de) 2007-04-25
ES2284202T3 (es) 2007-11-01
US6683070B2 (en) 2004-01-27
WO1998051281A1 (en) 1998-11-19
US6448296B2 (en) 2002-09-10
EP0995435A4 (de) 2004-11-10
US6274634B1 (en) 2001-08-14
CA2289618A1 (en) 1998-11-19
DE69837664T2 (de) 2008-01-03
US20010036966A1 (en) 2001-11-01
EP0995435A1 (de) 2000-04-26
US20030008010A1 (en) 2003-01-09
KR20010012188A (ko) 2001-02-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition