DE69835438D1 - Photo-empfindlichkeit-erhöhende conjugate zur targeting von pathogene - Google Patents
Photo-empfindlichkeit-erhöhende conjugate zur targeting von pathogeneInfo
- Publication number
- DE69835438D1 DE69835438D1 DE69835438T DE69835438T DE69835438D1 DE 69835438 D1 DE69835438 D1 DE 69835438D1 DE 69835438 T DE69835438 T DE 69835438T DE 69835438 T DE69835438 T DE 69835438T DE 69835438 D1 DE69835438 D1 DE 69835438D1
- Authority
- DE
- Germany
- Prior art keywords
- pathogene
- targeting
- photo
- sensitivity
- conjugate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/10—Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person
- A61K41/17—Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person by ultraviolet [UV] or infrared [IR] light, X-rays or gamma rays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US812606 | 1997-03-06 | ||
| US08/812,606 US6462070B1 (en) | 1997-03-06 | 1997-03-06 | Photosensitizer conjugates for pathogen targeting |
| PCT/US1998/004001 WO1998039011A1 (en) | 1997-03-06 | 1998-02-27 | Photosensitizer conjugates for pathogen targeting |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69835438D1 true DE69835438D1 (de) | 2006-09-14 |
| DE69835438T2 DE69835438T2 (de) | 2007-03-15 |
Family
ID=25210103
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69835438T Expired - Fee Related DE69835438T2 (de) | 1997-03-06 | 1998-02-27 | Photo-empfindlichkeit-erhöhende konjugate zur targeting von pathogene |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US6462070B1 (de) |
| EP (1) | EP1017397B1 (de) |
| JP (1) | JP2001513819A (de) |
| KR (1) | KR20000076016A (de) |
| CN (1) | CN1255063A (de) |
| AT (1) | ATE334676T1 (de) |
| AU (1) | AU737574B2 (de) |
| CA (1) | CA2283868C (de) |
| DE (1) | DE69835438T2 (de) |
| WO (1) | WO1998039011A1 (de) |
Families Citing this family (66)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6462070B1 (en) * | 1997-03-06 | 2002-10-08 | The General Hospital Corporation | Photosensitizer conjugates for pathogen targeting |
| US6919076B1 (en) | 1998-01-20 | 2005-07-19 | Pericor Science, Inc. | Conjugates of agents and transglutaminase substrate linking molecules |
| DE19827417B4 (de) * | 1998-06-19 | 2004-10-28 | Hahn, Rainer, Dr.Med.Dent. | Material zur unterschiedlichen Modifizierung der optischen Eigenschaften unterschiedlicher Zellen |
| US7015309B1 (en) | 1999-06-23 | 2006-03-21 | The Wistar Institute Of Anatomy And Biology | Pyrrhocoricin-derived peptides, and methods of use thereof |
| US20020169107A1 (en) * | 2001-01-19 | 2002-11-14 | Mallinckrodt Inc. | Novel aromatic azides for type I phototherapy |
| US7235685B2 (en) * | 2001-07-03 | 2007-06-26 | Mallinckrodt, Inc. | Aromatic sulfenates for type I phototherapy |
| EP1252517A4 (de) * | 2000-01-21 | 2004-10-20 | Wistar Inst | Biozidmoleküle, makromolekulare ziele und verfahren zur herstellung und verwendung |
| EP1272119B1 (de) * | 2000-02-11 | 2010-11-24 | The General Hospital Corporation | Photochemische gewebeverbindung |
| US7090497B1 (en) * | 2001-02-21 | 2006-08-15 | Harris David M | Method of periodontal laser treatment |
| GB0120022D0 (en) | 2001-08-16 | 2001-10-10 | Photobiotics Ltd | Conjugate |
| US6558653B2 (en) * | 2001-09-19 | 2003-05-06 | Scot N. Andersen | Methods for treating periodontal disease |
| US20040127892A1 (en) * | 2002-01-31 | 2004-07-01 | Harris David M. | Periodontal laser and methods |
| NL1020336C2 (nl) * | 2002-04-09 | 2003-10-13 | Photobiochem Leiden N V | Toepassing van een verbinding voor de bereiding van een farmaceutisch preparaat voor het behandelen van brandwonden, en een werkwijze voor het behandelen van brandwonden. |
| US20040052798A1 (en) * | 2002-09-12 | 2004-03-18 | Ceramoptec Industries, Inc. | Microbe reduction in the oral cavity with photosensitizers |
| WO2004044191A1 (en) * | 2002-11-14 | 2004-05-27 | Novartis Ag | Antimicrobial activity of antibodies producing reactive oxygen species |
| GB2397067B (en) | 2002-12-23 | 2005-05-11 | Destiny Pharma Ltd | Porphin & azaporphin derivatives with at least one cationic-nitrogen-containing meso-substituent for use in photodynamic therapy & in vitro sterilisation |
| NL1022597C2 (nl) * | 2003-02-05 | 2004-08-06 | Photobiochem N V | Toepassing van een fotosensitizerverbinding voor de bereiding van een farmaceutisch preparaat, werkwijze voor het bereiden van een farmaceutisch preparaat en een werkwijze voor het behandelen van een zoogdier. |
| GB2415372A (en) | 2004-06-23 | 2005-12-28 | Destiny Pharma Ltd | Non photodynamical or sonodynamical antimicrobial use of porphyrins and azaporphyrins containing at least one cationic-nitrogen-containing substituent |
| KR101277022B1 (ko) * | 2004-08-06 | 2013-06-24 | 파로스 라이프 코오포레이션 | 치료기와 관련 액세서리, 조성물 및 치료방법 |
| US20060047281A1 (en) | 2004-09-01 | 2006-03-02 | Syneron Medical Ltd. | Method and system for invasive skin treatment |
| AU2006283726C1 (en) | 2005-08-24 | 2015-05-07 | Immunogen, Inc. | Process for preparing maytansinoid antibody conjugates |
| EP1933941A2 (de) | 2005-08-25 | 2008-06-25 | Philip R. Houle | Behandlungssysteme zur abgabe von sensibilisatorlösungen |
| CA113237S (en) | 2005-10-26 | 2009-07-15 | John Kennedy | Phototherapy device |
| US20100016208A1 (en) * | 2005-11-15 | 2010-01-21 | The General Hospital Corporation | Photoactivatable antimicrobial agents |
| CA2535276A1 (en) * | 2006-02-06 | 2007-08-06 | John Kennedy | Therapy device and system and method for reducing harmful exposure to electromagnetic radiation |
| AU2006341380B2 (en) * | 2006-03-31 | 2013-01-10 | Emory University | Light activated antiviral materials and devices and methods for decontaminating virus infected environments |
| BRPI0714667A8 (pt) * | 2006-07-27 | 2016-10-18 | Ceramoptec Ind Inc | Conjugado molecular e respectivo uso |
| US20090030257A1 (en) * | 2007-07-25 | 2009-01-29 | Ceramoptec Industries Inc. | Anti-microbial photodynamic therapy |
| DK2244724T3 (en) * | 2008-01-07 | 2015-06-29 | Rapid Pathogen Screening Inc | Use of peptides for promoting wound healing |
| US9090670B2 (en) | 2008-01-07 | 2015-07-28 | Rapid Pathogen Screening, Inc. | Use of peptides for promoting wound healing |
| MX2010007860A (es) | 2008-01-17 | 2010-11-30 | Syneron Medical Ltd | Un aparato de eliminacion de vello para uso personal y metodo para usarlo. |
| WO2009093230A2 (en) | 2008-01-24 | 2009-07-30 | Syneron Medical Ltd. | A device, apparatus, and method of adipose tissue treatment |
| WO2009137062A2 (en) | 2008-05-05 | 2009-11-12 | The General Hospital Corporation | Photoactivatable antimicrobial agents and therapeutic and diagnostic methods of using same |
| US20100017750A1 (en) | 2008-07-16 | 2010-01-21 | Avner Rosenberg | User interface |
| US9314293B2 (en) | 2008-07-16 | 2016-04-19 | Syneron Medical Ltd | RF electrode for aesthetic and body shaping devices and method of using same |
| WO2010014728A1 (en) | 2008-07-29 | 2010-02-04 | Frontier Scientific Inc. | Use of tetrakis (n-alkylpyridinium) -porphyrin derivatives for killing microbes or preventing growth |
| US8859760B2 (en) | 2008-07-29 | 2014-10-14 | Frontier Scientific, Inc. | Compositions for killing or preventing the growth of microbes |
| BRPI0917921A2 (pt) | 2008-09-21 | 2015-11-10 | Syneron Medical Ltd | método e aparelho para tratamento de pele pessoal |
| US8606366B2 (en) | 2009-02-18 | 2013-12-10 | Syneron Medical Ltd. | Skin treatment apparatus for personal use and method for using same |
| US9278230B2 (en) | 2009-02-25 | 2016-03-08 | Syneron Medical Ltd | Electrical skin rejuvenation |
| SI2437790T1 (sl) | 2009-06-03 | 2019-07-31 | Immunogen, Inc. | Konjugacijske metode |
| EP2506773B1 (de) | 2009-12-06 | 2018-08-15 | Syneron Medical Ltd. | Vorrichtung zur hautpflege |
| MX339927B (es) | 2011-03-29 | 2016-06-16 | Immunogen Inc | Preparacion de conjugados de maitansinoides y anticuerpos mediante un proceso de una etapa. |
| KR101385196B1 (ko) * | 2012-05-17 | 2014-04-14 | 주식회사 유니크메디케어 | 광 조사를 이용한 광감각제―펩타이드를 유효성분으로 포함하는 발모 개선 또는 촉진용 조성물 및 이를 이용한 방법 |
| US20130310326A1 (en) | 2012-05-18 | 2013-11-21 | Rapid Pathogen Screening, Inc. | Histatin for Corneal Wound Healing and Ocular Surface Disease |
| JP2015522554A (ja) | 2012-06-04 | 2015-08-06 | サンコー・エナジー・インコーポレーテッド | パラフィン油及び沈降防止剤を含む製剤 |
| WO2013192521A1 (en) * | 2012-06-22 | 2013-12-27 | The General Hospital Corporation | β-LACTAMASE TARGETED PHOTOSENSITIZER FOR PESTICIDE AND PEST DETECTION |
| WO2014004680A1 (en) * | 2012-06-26 | 2014-01-03 | University Of Rochester | Catheter/stent system for activation of photodynamic therapy within the catheter/stent system |
| NZ707091A (en) | 2012-10-04 | 2018-12-21 | Immunogen Inc | Use of a pvdf membrane to purify cell-binding agent cytotoxic agent conjugates |
| US9581594B2 (en) | 2013-03-14 | 2017-02-28 | The United States Of America, As Represented By The Secretary Of The Navy | Porphyrin—modified antimicrobial peptides for application as indicators of microbial targets |
| WO2014159904A1 (en) * | 2013-03-14 | 2014-10-02 | The Government Of The United States Of America, As Represented By The Secretary Of The Navy | Porphyrin-modified antimicrobial peptides for application as indicators of microbial targets |
| US20160286801A1 (en) | 2013-03-15 | 2016-10-06 | Suncor Energy Inc. | Herbicidal Compositions |
| US12109429B2 (en) | 2015-07-28 | 2024-10-08 | Know Bio, Llc | Phototherapeutic light for treatment of pathogens |
| US10569097B2 (en) | 2015-07-28 | 2020-02-25 | Photonmd, Inc. | Systems and methods for phototherapeutic modulation of nitric oxide |
| CN107648587A (zh) * | 2017-10-23 | 2018-02-02 | 安徽科技学院 | 抗菌肽以及融合蛋白在制备治疗幽门螺旋杆菌病的药物中的应用 |
| CN108588093A (zh) * | 2018-04-11 | 2018-09-28 | 湖南文理学院 | 东方铃蟾肠道芽孢杆菌表达蛋白对泌乳奶牛粪便具有强除臭能力的ness1-a基因 |
| US12138308B2 (en) | 2018-09-20 | 2024-11-12 | Enbiar Inc. | Polymer composite for helicobacter pylori recognition and composition for photodynamic therapy comprising same |
| JP7168770B2 (ja) * | 2018-09-20 | 2022-11-09 | エンビアル インコーポレイテッド | ヘリコバクター・ピロリ認知用高分子複合体及びそれを含む光線力学治療用組成物 |
| JP7588289B2 (ja) | 2019-02-15 | 2024-11-22 | ニュートリエン・エージー・ソリューションズ・(カナダ)・インコーポレイテッド | 植物の健康を増進するプロトポルフィリンix誘導体及びその使用 |
| US12447354B2 (en) | 2020-03-19 | 2025-10-21 | Know Bio, Llc | Illumination devices for inducing biological effects |
| US11147984B2 (en) | 2020-03-19 | 2021-10-19 | Know Bio, Llc | Illumination devices for inducing biological effects |
| US12011611B2 (en) | 2020-03-19 | 2024-06-18 | Know Bio, Llc | Illumination devices for inducing biological effects |
| US11986666B2 (en) | 2020-03-19 | 2024-05-21 | Know Bio, Llc | Illumination devices for inducing biological effects |
| US12347337B2 (en) | 2020-12-10 | 2025-07-01 | Know Bio, Llc | Enhanced testing and characterization techniques for phototherapeutic light treatments |
| US11654294B2 (en) | 2021-03-15 | 2023-05-23 | Know Bio, Llc | Intranasal illumination devices |
| US12115384B2 (en) | 2021-03-15 | 2024-10-15 | Know Bio, Llc | Devices and methods for illuminating tissue to induce biological effects |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5283255A (en) * | 1987-01-20 | 1994-02-01 | The University Of British Columbia | Wavelength-specific cytotoxic agents |
| EP0349578B2 (de) | 1987-03-02 | 1998-10-28 | Enzon Labs Inc. | Organismus als Träger für "Single Chain Antibody Domain (SCAD)". |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| US5096815A (en) | 1989-01-06 | 1992-03-17 | Protein Engineering Corporation | Generation and selection of novel dna-binding proteins and polypeptides |
| US5198346A (en) | 1989-01-06 | 1993-03-30 | Protein Engineering Corp. | Generation and selection of novel DNA-binding proteins and polypeptides |
| US5041078A (en) * | 1989-03-06 | 1991-08-20 | Baylor Research Foundation, A Nonprofit Corporation Of The State Of Texas | Photodynamic viral deactivation with sapphyrins |
| US5244671A (en) * | 1991-01-29 | 1993-09-14 | Cytopharm, Inc. | Derivatives of porphycene for photodynamic therapy of cancer |
| WO1992014493A1 (en) * | 1991-02-20 | 1992-09-03 | Christopher Capelli | Non-protein intracellular receptor binding conjugates and a method of use thereof |
| US5486503A (en) | 1991-11-01 | 1996-01-23 | The Trustees Of Boston University | Anti-fungal histatin-based peptides |
| US6462070B1 (en) * | 1997-03-06 | 2002-10-08 | The General Hospital Corporation | Photosensitizer conjugates for pathogen targeting |
| JP2001510773A (ja) * | 1997-07-28 | 2001-08-07 | ダーマトレイザー テクノロジーズ リミテッド | 光線療法に基づく病原体の治療方法及びそれを達成するための組成物 |
-
1997
- 1997-03-06 US US08/812,606 patent/US6462070B1/en not_active Expired - Fee Related
-
1998
- 1998-02-27 WO PCT/US1998/004001 patent/WO1998039011A1/en not_active Ceased
- 1998-02-27 CA CA002283868A patent/CA2283868C/en not_active Expired - Fee Related
- 1998-02-27 EP EP98908829A patent/EP1017397B1/de not_active Expired - Lifetime
- 1998-02-27 AU AU66767/98A patent/AU737574B2/en not_active Ceased
- 1998-02-27 AT AT98908829T patent/ATE334676T1/de not_active IP Right Cessation
- 1998-02-27 CN CN98804809A patent/CN1255063A/zh active Pending
- 1998-02-27 DE DE69835438T patent/DE69835438T2/de not_active Expired - Fee Related
- 1998-02-27 KR KR1019997008102A patent/KR20000076016A/ko not_active Withdrawn
- 1998-02-27 JP JP53864298A patent/JP2001513819A/ja not_active Withdrawn
-
2002
- 2002-05-09 US US10/143,593 patent/US7268155B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP1017397A4 (de) | 2004-06-16 |
| US6462070B1 (en) | 2002-10-08 |
| CA2283868C (en) | 2008-05-06 |
| CN1255063A (zh) | 2000-05-31 |
| AU737574B2 (en) | 2001-08-23 |
| US7268155B2 (en) | 2007-09-11 |
| US20020183245A1 (en) | 2002-12-05 |
| CA2283868A1 (en) | 1998-09-11 |
| WO1998039011A1 (en) | 1998-09-11 |
| DE69835438T2 (de) | 2007-03-15 |
| ATE334676T1 (de) | 2006-08-15 |
| EP1017397A1 (de) | 2000-07-12 |
| AU6676798A (en) | 1998-09-22 |
| KR20000076016A (ko) | 2000-12-26 |
| EP1017397B1 (de) | 2006-08-02 |
| JP2001513819A (ja) | 2001-09-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |