[go: up one dir, main page]

DE69829254D1 - Arzneistoffzubereitung mit kontrollierter Wirkstofffreisetzungsrate - Google Patents

Arzneistoffzubereitung mit kontrollierter Wirkstofffreisetzungsrate

Info

Publication number
DE69829254D1
DE69829254D1 DE69829254T DE69829254T DE69829254D1 DE 69829254 D1 DE69829254 D1 DE 69829254D1 DE 69829254 T DE69829254 T DE 69829254T DE 69829254 T DE69829254 T DE 69829254T DE 69829254 D1 DE69829254 D1 DE 69829254D1
Authority
DE
Germany
Prior art keywords
drug
release rate
preparation
controlled
drug release
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69829254T
Other languages
English (en)
Other versions
DE69829254T2 (de
Inventor
Makoto Suzuki
Kenji Ishigaki
Minoru Okada
Kenji Ono
Shuichi Narita-Shi Kasai
Katsumi Imamori
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hisamitsu Pharmaceutical Co Inc
Original Assignee
SSP Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SSP Co Ltd filed Critical SSP Co Ltd
Publication of DE69829254D1 publication Critical patent/DE69829254D1/de
Application granted granted Critical
Publication of DE69829254T2 publication Critical patent/DE69829254T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69829254T 1997-10-27 1998-10-14 Arzneistoffzubereitung mit kontrollierter Wirkstofffreisetzungsrate Expired - Lifetime DE69829254T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP29400897A JP4234803B2 (ja) 1997-10-27 1997-10-27 薬物放出速度が制御された医薬組成物
JP29400897 1997-10-27

Publications (2)

Publication Number Publication Date
DE69829254D1 true DE69829254D1 (de) 2005-04-14
DE69829254T2 DE69829254T2 (de) 2005-08-18

Family

ID=17802062

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69829254T Expired - Lifetime DE69829254T2 (de) 1997-10-27 1998-10-14 Arzneistoffzubereitung mit kontrollierter Wirkstofffreisetzungsrate

Country Status (9)

Country Link
US (1) US6375988B1 (de)
EP (1) EP0913149B1 (de)
JP (1) JP4234803B2 (de)
KR (1) KR100535319B1 (de)
CN (1) CN1136842C (de)
CA (1) CA2251281C (de)
DE (1) DE69829254T2 (de)
ES (1) ES2239376T3 (de)
TW (1) TW520292B (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6974578B1 (en) 1993-12-28 2005-12-13 Allergan, Inc. Method for treating secretions and glands using botulinum toxin
KR100236771B1 (ko) * 1997-04-01 2000-02-01 성재갑 히아루론산을 이용한 약물의 서방성 미세입자 제형
US7276251B2 (en) * 1997-04-01 2007-10-02 Lg Life Sciences, Ltd., Inc. Sustained-release composition of drugs encapsulated in microparticles of hyaluronic acid
US7022683B1 (en) * 1998-05-13 2006-04-04 Carrington Laboratories, Inc. Pharmacological compositions comprising pectins having high molecular weights and low degrees of methoxylation
US7582311B1 (en) * 1999-10-15 2009-09-01 Genentech, Inc. Injection vehicle for polymer-based formulations
US6544555B2 (en) 2000-02-24 2003-04-08 Advancis Pharmaceutical Corp. Antibiotic product, use and formulation thereof
US20020068078A1 (en) 2000-10-13 2002-06-06 Rudnic Edward M. Antifungal product, use and formulation thereof
US6777000B2 (en) * 2001-02-28 2004-08-17 Carrington Laboratories, Inc. In-situ gel formation of pectin
US7494669B2 (en) * 2001-02-28 2009-02-24 Carrington Laboratories, Inc. Delivery of physiological agents with in-situ gels comprising anionic polysaccharides
WO2002100425A1 (fr) * 2001-06-11 2002-12-19 Ltt Institute Co., Ltd. Composition a base d'aggregats pour preparation a liberation prolongee, procede de production afferent, et preparation a liberation prolongee contenant ladite composition
GB0129489D0 (en) * 2001-12-10 2002-01-30 Quadrant Healthcare Uk Ltd Sustained-release compositions
EP1787643A1 (de) * 2004-09-09 2007-05-23 Jimenez Bayardo, Arturo Implantat und mikrokugeln zur dauerhaften abgabe von medikamenten zur ophthalmischen anwendung und herstellungsverfahren dafür
US20070141160A1 (en) * 2005-12-15 2007-06-21 Brown Laura J Method of treatment for osteoarthritis by local intra-articular injection of microparticles
KR100939983B1 (ko) * 2006-10-31 2010-02-03 주식회사 엘지생명과학 히아루론산-소수성 폴리 아미노산 공중합체
JP5255775B2 (ja) * 2007-03-15 2013-08-07 ピアス株式会社 水性ゲル、皮膚外用剤および化粧料
WO2013030348A1 (en) 2011-09-02 2013-03-07 Novozymes Biopharma Dk A/S Oral formulations containing hyaluronic acid for sustained drug release
WO2013052012A1 (en) * 2011-10-03 2013-04-11 Nanyang Technological University Cationic peptidopolysaccharides with excellent broad- spectrum antimicrobial activities and high selectivity
EP2606896B1 (de) * 2011-12-23 2014-08-27 AAP Implantate AG Sterile Emulsion mit Hyaluronat und Glucocorticoid sowie Verwendung einer solchen Emulsion bei der Behandlung entzündlicher Gelenkerkrankungen
JP6120397B2 (ja) * 2012-10-11 2017-04-26 ポーラ化成工業株式会社 キトサン及びヒアルロナンを含むナノ粒子の製造方法
CN105517539A (zh) 2013-08-21 2016-04-20 Nrl制药股份有限公司 微粒的制造方法
CN106665645B (zh) * 2016-12-22 2019-08-27 德州京信药业有限公司 一种精制敌百虫组合物及其制备方法与应用
KR102610937B1 (ko) * 2018-10-30 2023-12-08 (주)아모레퍼시픽 가교 히알루론산 조성물 및 이의 제조방법
KR102501175B1 (ko) * 2020-02-03 2023-02-16 엠앤에이치바이오 주식회사 난청 치료용 제어 방출형 제제 및 이의 제조방법
KR102597505B1 (ko) * 2020-06-01 2023-11-02 주식회사 엘지화학 고분자 마이크로 입자의 제조방법, 고분자 마이크로 입자, 이를 포함하는 의료용 조성물, 미용 조성물, 의료 용품 및 미용 용품
US12296054B2 (en) 2020-06-01 2025-05-13 Lg Chem, Ltd. Method of preparing polymeric microparticles, polymeric microparticles, medical composition, cosmetic composition, medical articles and cosmetic articles using the same
KR20230047294A (ko) * 2021-09-30 2023-04-07 주식회사 엘지화학 마이크로 캐리어, 세포 복합체 및 이를 포함하는 의료용 조성물, 미용 조성물, 의료 용품 및 미용 용품

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60100516A (ja) * 1983-11-04 1985-06-04 Takeda Chem Ind Ltd 徐放型マイクロカプセルの製造法
DE3686275T2 (de) * 1985-01-11 1993-03-18 Teijin Ltd Praeparate mit verzoegerter freisetzung.
JPS61253065A (ja) * 1985-05-02 1986-11-10 片倉チツカリン株式会社 キトサン誘導体およびコラ−ゲンの複合材の医用材料およびその製造法
JP2837675B2 (ja) * 1987-09-22 1998-12-16 中外製薬株式会社 徐放性微粒製剤
EP0528971B1 (de) 1990-05-14 1999-09-01 JERNBERG, Gary R. Chirurgisches implantat und verfahren zum einbetten von chemotherapeutika
JPH04124127A (ja) * 1990-09-14 1992-04-24 Chugai Pharmaceut Co Ltd マイクロカプセル型徐放性製剤及びその製造法
IT1243390B (it) * 1990-11-22 1994-06-10 Vectorpharma Int Composizioni farmaceutiche in forma di particelle atte al rilascio controllato di sostanze farmacologicamente attive e procedimento per la loro preparazione.
JP3283288B2 (ja) * 1991-03-08 2002-05-20 電気化学工業株式会社 生理活性ペプチド製剤
JPH04282322A (ja) * 1991-03-08 1992-10-07 Denki Kagaku Kogyo Kk 生物活性ペプチド製剤
JPH0565231A (ja) * 1991-03-12 1993-03-19 Takeda Chem Ind Ltd エリスロポエチンの持続性製剤
US5416071A (en) * 1991-03-12 1995-05-16 Takeda Chemical Industries, Ltd. Water-soluble composition for sustained-release containing epo and hyaluronic acid
DE4115454A1 (de) * 1991-05-11 1992-11-12 Basf Ag Eisen-(iii)-hyaluronate
JP3449738B2 (ja) * 1991-07-10 2003-09-22 武田薬品工業株式会社 水溶性組成物
AU3064892A (en) * 1991-11-07 1993-06-07 University Of Southern California Compositions and methods for preventing adhesion formation
IT1254170B (it) * 1991-12-18 1995-09-11 Mini Ricerca Scient Tecnolog Membrane composite per la rigenerazione guidata di tessuti
GB9202464D0 (en) * 1992-02-05 1992-03-18 Danbiosyst Uk Composition for nasal administration
GB9206509D0 (en) 1992-03-25 1992-05-06 Jevco Ltd Heteromorphic sponges containing active agents
US6197346B1 (en) 1992-04-24 2001-03-06 Brown Universtiy Research Foundation Bioadhesive microspheres and their use as drug delivery and imaging systems
JPH05310580A (ja) * 1992-04-30 1993-11-22 Shiseido Co Ltd 眼内灌流用液剤
JPH06100468A (ja) * 1992-09-25 1994-04-12 Kibun Food Chemifa Co Ltd 徐放性組成物
US5399358A (en) * 1993-11-12 1995-03-21 Edward Mendell Co., Inc. Sustained release formulations for 24 hour release of metroprolol
IT1273742B (it) * 1994-08-01 1997-07-09 Lifegroup Spa Composizioni ad elevata bioadesivita' e mucoadesivita' utili per il trattamento di epitali e mucose
JPH08198724A (ja) * 1995-01-19 1996-08-06 Yakult Honsha Co Ltd 皮膚化粧料
JPH09221420A (ja) * 1995-12-15 1997-08-26 Takeda Chem Ind Ltd ヒドロキサム酸類の徐放性製剤
KR100236771B1 (ko) * 1997-04-01 2000-02-01 성재갑 히아루론산을 이용한 약물의 서방성 미세입자 제형
US5885609A (en) * 1997-05-23 1999-03-23 Northeastern University Biocompatible articles and method for making same
US6391336B1 (en) * 1997-09-22 2002-05-21 Royer Biomedical, Inc. Inorganic-polymer complexes for the controlled release of compounds including medicinals

Also Published As

Publication number Publication date
TW520292B (en) 2003-02-11
CN1220874A (zh) 1999-06-30
ES2239376T3 (es) 2005-09-16
CA2251281C (en) 2007-09-11
JP4234803B2 (ja) 2009-03-04
KR100535319B1 (ko) 2006-04-21
CA2251281A1 (en) 1999-04-27
HK1019142A1 (en) 2000-01-14
EP0913149A1 (de) 1999-05-06
KR19990037094A (ko) 1999-05-25
EP0913149B1 (de) 2005-03-09
DE69829254T2 (de) 2005-08-18
JPH11130697A (ja) 1999-05-18
CN1136842C (zh) 2004-02-04
US6375988B1 (en) 2002-04-23

Similar Documents

Publication Publication Date Title
DE69829254D1 (de) Arzneistoffzubereitung mit kontrollierter Wirkstofffreisetzungsrate
ATE256389T1 (de) Mikrokapseln mit einfach einstellbarer abgaberate
NO993484D0 (no) Farmasoeytisk preparat med regulert frigjoeringsvirkning
ATE209497T1 (de) Azithromycin enthaltende arzneiverabreichungsformen mit gesteuerter wirkstoffabgabe
ATE308319T1 (de) Dosierungsform mit verlängerter wirkstoffabgabe
ATE548029T1 (de) Wirkstoffabgabevorrichtung mit verzögerter freisetzung
DE69942928D1 (de) Therapeutische formulierung zur verabreichung von tolterodin mit kontrollierter freisetzung
ID23874A (id) Obat
DE69810608D1 (de) Eingekapseltes material mit kontrollierter freisetzung
DK0746310T3 (da) Præparat med styret afgivelse
DE69821457D1 (de) Zusammensetzungen mit kontrollierter Wirkstoffabgabe
DE69622780D1 (de) Transdermales therapeutisches System mit kontrollierter Wirkstofffreisetzung
DE69825049D1 (de) Im magen verweilende mikrosphären mit gesteuerter freisetzung zur verbesserten arzneistoffabgabe
DE69319320D1 (de) Arzneimittelzubereitung mit verspätet einsetzender kontinuierlicher Freisetzung
HUP0301242A3 (en) Controlled release drug dosage form
DE69916922D1 (de) Ibuprofenhaltige Arzneizubereitung
DK0998272T3 (da) Farmaceutisk præparat til kombinationen piperidinoalkanoldekongestivum
DE69739950D1 (de) Kaugummi enthaltend azyklische carboxamide mit kontrollierter freisetzung
BR9607752B1 (pt) formulação farmacêutica de microcápsula de liberação controlada.
DE69810189D1 (de) Zusammensetzungen mit kontrollierter Wirkstoffabgabe
NO20001375L (no) Legemiddelformulering med kontrollert virkestoffrigivning
DE59915033D1 (de) Pharmazeutische Zubereitung
ATE237320T1 (de) Venlafaxinhaltiges arzneimittel mit verlängerter wirkstoffabgabe
BR9708528A (pt) Terapia com libertação uniforme de droga
ATE261764T1 (de) Mikrokapseln mit veränderlicher freisetzung

Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: BIOMEDIX CO., LTD, TOKOY, JP

8327 Change in the person/name/address of the patent owner

Owner name: HISAMITSU MEDICAL CO., LTD., TOKIO/TOKYO, JP

8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: HISAMITSU PHARMACEUTICAL CO., INC., TOSU, SAGA, JP