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DE69825164D1 - Arzneizubereitungen enthaltend vitamin d und kalzium,ihre herstellung und therapeutische verwendung - Google Patents

Arzneizubereitungen enthaltend vitamin d und kalzium,ihre herstellung und therapeutische verwendung

Info

Publication number
DE69825164D1
DE69825164D1 DE69825164T DE69825164T DE69825164D1 DE 69825164 D1 DE69825164 D1 DE 69825164D1 DE 69825164 T DE69825164 T DE 69825164T DE 69825164 T DE69825164 T DE 69825164T DE 69825164 D1 DE69825164 D1 DE 69825164D1
Authority
DE
Germany
Prior art keywords
calcium
production
containing vitamin
therapeutic use
preparations containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69825164T
Other languages
English (en)
Inventor
Maurizio Valleri
Alessandro Tosetti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Menarini International Operations Luxembourg SA
Original Assignee
Menarini International Operations Luxembourg SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Menarini International Operations Luxembourg SA filed Critical Menarini International Operations Luxembourg SA
Application granted granted Critical
Publication of DE69825164D1 publication Critical patent/DE69825164D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Inorganic Chemistry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Vascular Medicine (AREA)
  • Nutrition Science (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69825164T 1997-07-30 1998-07-21 Arzneizubereitungen enthaltend vitamin d und kalzium,ihre herstellung und therapeutische verwendung Expired - Fee Related DE69825164D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT97FI000184A ITFI970184A1 (it) 1997-07-30 1997-07-30 Composizioni farmaceutiche contenenti vitamina d e calcio,loro preparazione ed uso terapeutico
PCT/EP1998/004567 WO1999006051A1 (en) 1997-07-30 1998-07-21 Pharmaceutical compositions containing vitamin d and calcium, their preparation and therapeutic use

Publications (1)

Publication Number Publication Date
DE69825164D1 true DE69825164D1 (de) 2004-08-26

Family

ID=11352223

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69825164T Expired - Fee Related DE69825164D1 (de) 1997-07-30 1998-07-21 Arzneizubereitungen enthaltend vitamin d und kalzium,ihre herstellung und therapeutische verwendung

Country Status (28)

Country Link
US (1) US7067154B1 (de)
EP (1) EP0999843B1 (de)
JP (1) JP4497496B2 (de)
KR (1) KR100573421B1 (de)
AT (1) ATE271387T1 (de)
AU (1) AU8978198A (de)
BG (1) BG65044B1 (de)
BR (1) BR9810832B1 (de)
CA (1) CA2299420C (de)
CZ (1) CZ297670B6 (de)
DE (1) DE69825164D1 (de)
EA (1) EA002492B1 (de)
EE (1) EE04046B1 (de)
ES (1) ES2223135T3 (de)
HU (1) HU226112B1 (de)
ID (1) ID23504A (de)
IL (1) IL134268A0 (de)
IS (1) IS5359A (de)
IT (1) ITFI970184A1 (de)
NO (1) NO20000310D0 (de)
PL (1) PL189295B1 (de)
PT (1) PT999843E (de)
RS (1) RS49703B (de)
SI (1) SI0999843T1 (de)
SK (1) SK284873B6 (de)
TR (1) TR200000261T2 (de)
UA (1) UA61968C2 (de)
WO (1) WO1999006051A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040071789A1 (en) * 2002-02-14 2004-04-15 Baron John A Calcium supplementation to reduce prostate cancer risk
ES2192136B1 (es) * 2002-01-04 2005-03-16 Italfarmaco, S.A. Composiciones farmaceuticas para el tratamiento o prevencion de la osteoporosis.
ITFI20030194A1 (it) * 2003-07-17 2005-01-18 Menarini Int Operations Lu Sa Composizione farmaceutiche effervescenti contenenti
MY144631A (en) 2004-05-24 2011-10-14 Nycomed Pharma As Particulate comprising a calcium-containing compound and a sugar alcohol
MXPA06013840A (es) 2004-06-01 2007-04-16 Nycomed Pharma As Tableta masticable, chupable y tragable que contiene un compuesto que contiene calcio, como una sustancia activa.
CN103479582A (zh) 2005-02-03 2014-01-01 武田奈科明有限公司 制备含钙组合物的快速湿聚结方法
DE602006001295D1 (de) 2005-02-03 2008-07-03 Nycomed Pharma As Schmelzgranulation einer zusammensetzung mit einer calziumhaltigen verbindung
CA2624897C (en) * 2005-10-12 2017-02-14 Proventiv Therapeutics, Llc Methods and articles for treating 25-hydroxyvitamin d insufficiency and deficiency
UA95093C2 (uk) 2005-12-07 2011-07-11 Нікомед Фарма Ас Спосіб одержання кальцієвмісної сполуки
CN101365426B (zh) 2005-12-07 2012-08-08 奈科明制药有限公司 预先压实的含钙组合物
MXPA05014091A (es) * 2005-12-20 2007-06-20 Leopoldo De Jesus Espinosa Abdala Composiciones farmaceuticas que comprenden derivados de esteroides sinteticos, minerales y el metabolito activo de la vitamina d, 1,25(oh)2d3 (calcitriol) para la prevencion y tratamiento de la osteoporosis y el control de los sintomas de la menopaus
CA2835910C (en) 2007-04-25 2016-06-28 Warner Chilcott Company, Llc Improved vitamin d content uniformity in pharmaceutical dosage forms
SI2358374T1 (sl) 2008-11-17 2014-01-31 Takeda Nycomed As Izboljšana topna stabilnost tablet, ki vsebujejo kalcijev karbonat
TR200900880A2 (tr) 2009-02-05 2010-08-23 Bi̇lgi̇ç Mahmut Tek bir dozaj formunda kombine edilen farmasötik bileşimler.
TR200900878A2 (tr) 2009-02-05 2010-08-23 Bi̇lgi̇ç Mahmut Tek bir dozaj formunda kombine edilen farmasötik formülasyonlar
TR200908237A2 (tr) 2009-11-02 2011-05-23 Bi̇lgi̇ç Mahmut Kalsiyum ve D vitamini içeren farmasötik bileşimler.
US20120015913A1 (en) 2010-07-15 2012-01-19 Delansorne Remi Formulations of 14-EPI-Analogues of Vitamin D
JP6554034B2 (ja) * 2013-08-09 2019-07-31 日東薬品工業株式会社 カルシウム剤
CN105166935B (zh) * 2015-09-01 2018-08-31 张伟 一种含有维生素d3的液体制剂及其制备方法
FI3787596T3 (fi) 2018-05-02 2025-09-29 Ferring Bv Parannettuja farmaseuttisia formulaatioita
KR102211287B1 (ko) * 2018-12-21 2021-02-03 (주)휴온스 비타민 d 또는 이의 유도체를 포함하는 안정성이 개선된 액상 제제
MX2023010739A (es) * 2021-03-12 2023-09-20 Nicoventures Trading Ltd Productos orales con sistema autoemulsificante.
WO2025079114A1 (en) * 2023-10-13 2025-04-17 Vytals Wellbeing India Pvt. Ltd. A self-nano emulsifying drug formulation for cholecalciferol

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2073271A1 (en) * 1969-12-11 1971-10-01 Boivin Jean Calcium salt - vitamin d2 compn - for treatment of decalcification of
ZA813205B (en) * 1980-12-05 1983-03-30 Smith Kline French Lab Dosage units
DK8603837A (de) * 1985-08-13 1987-02-14
US5624683A (en) * 1986-08-06 1997-04-29 Eisai Co., Ltd. Sustained-release multi-granule tablet
DE69124223T2 (de) * 1990-02-05 1997-04-30 Lifescience Corp Vitamine und mineralien enthaltende nahrungszusätze
JPH06504259A (ja) * 1990-05-16 1994-05-19 ボード オブ リージェンツ，ザ ユニバーシティ オブ テキサス システム 高コレステロール血症および細胞過増殖性障害の予防および処置用処方および方法
RO113611B1 (ro) * 1990-08-03 1998-09-30 Asta Pharma Ag Preparate solide de ifosfamida, administrate oral si procedeu de obtinere
IL103224A (en) * 1992-09-18 1998-08-16 Teva Pharma Stabilized pharmaceutical compositions containing derivatives of vitamins d2 and d3
FR2724844B1 (fr) 1994-09-23 1997-01-24 Innothera Lab Sa Association therapeutique vitamino-calcique, son procede d'obtention et son utilisation
IL115241A (en) * 1994-09-26 2000-08-31 American Cyanamid Co Calcium dietary supplement
FR2760639B1 (fr) * 1997-03-14 2000-09-22 Innothera Lab Sa Association therapeutique mineralo-vitaminique sous forme de preparation unitaire liquide buvable

Also Published As

Publication number Publication date
SK802000A3 (en) 2000-07-11
EA200000181A1 (ru) 2000-10-30
EP0999843A1 (de) 2000-05-17
JP2001511453A (ja) 2001-08-14
ITFI970184A1 (it) 1999-01-30
NO20000310L (no) 2000-01-21
CA2299420C (en) 2009-04-21
KR20010022319A (ko) 2001-03-15
ES2223135T3 (es) 2005-02-16
SK284873B6 (sk) 2006-01-05
ATE271387T1 (de) 2004-08-15
HU226112B1 (en) 2008-04-28
SI0999843T1 (en) 2005-02-28
BG65044B1 (bg) 2007-01-31
TR200000261T2 (tr) 2000-09-21
PL189295B1 (pl) 2005-07-29
ID23504A (id) 2000-04-27
EP0999843B1 (de) 2004-07-21
YU3700A (sh) 2002-11-15
BG104057A (en) 2000-07-31
PL338237A1 (en) 2000-10-09
BR9810832A (pt) 2000-07-25
IL134268A0 (en) 2001-04-30
KR100573421B1 (ko) 2006-04-26
UA61968C2 (en) 2003-12-15
BR9810832B1 (pt) 2010-11-16
EE200000054A (et) 2000-10-16
US7067154B1 (en) 2006-06-27
JP4497496B2 (ja) 2010-07-07
EA002492B1 (ru) 2002-06-27
CZ297670B6 (cs) 2007-02-28
AU8978198A (en) 1999-02-22
IS5359A (is) 2000-01-24
PT999843E (pt) 2004-11-30
NO20000310D0 (no) 2000-01-21
CA2299420A1 (en) 1999-02-11
EE04046B1 (et) 2003-06-16
WO1999006051A1 (en) 1999-02-11
CZ2000199A3 (cs) 2000-05-17
HK1027751A1 (en) 2001-01-23
RS49703B (sr) 2007-12-31
HUP0100539A2 (hu) 2001-08-28

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Legal Events

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8339 Ceased/non-payment of the annual fee