DE69810724D1 - Verwendung von Protein C Inhibitor zur Behandlung disseminierter intravasaler Gerinnung (DIC) - Google Patents
Verwendung von Protein C Inhibitor zur Behandlung disseminierter intravasaler Gerinnung (DIC)Info
- Publication number
- DE69810724D1 DE69810724D1 DE69810724T DE69810724T DE69810724D1 DE 69810724 D1 DE69810724 D1 DE 69810724D1 DE 69810724 T DE69810724 T DE 69810724T DE 69810724 T DE69810724 T DE 69810724T DE 69810724 D1 DE69810724 D1 DE 69810724D1
- Authority
- DE
- Germany
- Prior art keywords
- inhibitor
- protein
- dic
- treatment
- intravascular coagulation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 102000000873 Protein C Inhibitor Human genes 0.000 title abstract 2
- 108010001953 Protein C Inhibitor Proteins 0.000 title abstract 2
- 229940122929 Protein C inhibitor Drugs 0.000 title abstract 2
- 208000009190 disseminated intravascular coagulation Diseases 0.000 title 1
- 206010020608 Hypercoagulation Diseases 0.000 abstract 1
- 230000023555 blood coagulation Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000003027 hypercoagulation Effects 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 238000002415 sodium dodecyl sulfate polyacrylamide gel electrophoresis Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/57—Protease inhibitors from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
- C07K14/8121—Serpins
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Zoology (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP9230294A JPH1160500A (ja) | 1997-08-11 | 1997-08-11 | 血液凝固異常亢進抑制剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69810724D1 true DE69810724D1 (de) | 2003-02-20 |
| DE69810724T2 DE69810724T2 (de) | 2003-05-08 |
Family
ID=16905575
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69810724T Expired - Fee Related DE69810724T2 (de) | 1997-08-11 | 1998-08-11 | Verwendung von Protein C Inhibitor zur Behandlung disseminierter intravasaler Gerinnung (DIC) |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US5948752A (de) |
| EP (1) | EP0904785B1 (de) |
| JP (1) | JPH1160500A (de) |
| AT (1) | ATE231001T1 (de) |
| CA (1) | CA2244801A1 (de) |
| DE (1) | DE69810724T2 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002010783A (ja) * | 2000-06-29 | 2002-01-15 | Jcr Pharmaceuticals Co Ltd | 改変型ヒトプロテインｃインヒビター |
| TW200407335A (en) * | 2002-07-22 | 2004-05-16 | Chugai Pharmaceutical Co Ltd | Non-neutralizing antibody to inhibit the inactivation of activated protein C |
| US20060167230A1 (en) * | 2003-01-20 | 2006-07-27 | Takaki Koga | Anti-pci neutralizing antibody |
| FR2945126B1 (fr) * | 2009-04-29 | 2019-11-01 | Commissariat A L'energie Atomique | Procede et appareil de comptage des thrombocytes |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3705745A1 (de) * | 1987-02-23 | 1988-09-01 | Behringwerke Ag | Protein c-inhibitor (pci) als pharmazeutikum und in vitro-diagnostikum, verfahren zur herstellung eines solchen pharmazeutikums oder diagnostikums sowie ein mittel enthaltend pci |
| WO1993000926A1 (en) * | 1991-07-02 | 1993-01-21 | Children's Medical Center Corporation | Treatment of periodontal disease with protease inhibitors |
-
1997
- 1997-08-11 JP JP9230294A patent/JPH1160500A/ja active Pending
-
1998
- 1998-08-11 AT AT98115110T patent/ATE231001T1/de not_active IP Right Cessation
- 1998-08-11 US US09/132,534 patent/US5948752A/en not_active Expired - Fee Related
- 1998-08-11 EP EP98115110A patent/EP0904785B1/de not_active Expired - Lifetime
- 1998-08-11 CA CA002244801A patent/CA2244801A1/en not_active Abandoned
- 1998-08-11 DE DE69810724T patent/DE69810724T2/de not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US5948752A (en) | 1999-09-07 |
| EP0904785A1 (de) | 1999-03-31 |
| DE69810724T2 (de) | 2003-05-08 |
| CA2244801A1 (en) | 1999-02-11 |
| EP0904785B1 (de) | 2003-01-15 |
| JPH1160500A (ja) | 1999-03-02 |
| ATE231001T1 (de) | 2003-02-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |